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Fig. 1. Modulation of hipk affects wing development. (A)
Wild-type wing. (B,C) Reducing hipk function by
generating somatic hipk4 clones (B) or through expression
of UAS-hipk-RNAi in the wing with sd-gal4 (C) both led to
the loss of the wing margin (arrow). (D,E) Overexpression of
hipk in the wing blade with the omb-gal4 driver caused the
formation of an additional wing margin (D) and outgrowths from the ventral
side of the wing (E). (F) Misexpressing two copies of hipk led
to the formation of additional wing tissue outgrowths.