spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article
(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.


Figure 4


Fig. 4. Shortened cycle 11 interphase of mnk nopo-derived embryos. (A,B) Cell-cycle timing during cortical embryonic divisions. Bar graph (A) shows mean cycle 11 interphase lengths for various genotypes. Table (B) summarizes mean cycle 11-13 interphase (I) and mitosis (M) lengths. n, number of embryos. Error bars (A) and ±values (B) represent s.e.m. Single and double asterisks mark interphases significantly shorter than wild type (P<0.01 and <0.001, respectively). (C,D) Immunoblotting reveals normal pY15-CDK1 (C) and Cyclin B (D) levels in mnk nopoZ1447-derived embryos (1-2 hours). Control grp-derived embryos have reduced pY15-CDK1 levels. Anti-{alpha}-tubulin or anti-GAPDH was used as a loading control.





Right arrow Return to article