Platelet-derived growth factor-A and its receptor are expressed in separate, but adjacent cell layers of the mouse embryo

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Azar, Y. and Eyal-Giladi, H (1981). Interaction of epiblast and hypoblast in the formation of the primitive streak and the embryonic axis in chick, as revealed by hypoblast-rotation experiments. J. Embryol. exp. Morphol 61, 133-141.[Medline]

Bovolenta, P. and Dodd, J (1991). Perturbation of neuronal differentiation and axon guidance in the spinal cord of mouse embryos lacking a floor plate: analysis of Danforth's short tail mutation. Development 113, 625-639.[Abstract]

Cooke, J. and Wong, A (1991). Growth-factor-related proteins that are inducers in early amphibian development may mediate similar steps in amniote (bird) embryogenesis. Development 111, 197-212.[Abstract]

Doolittle, R. F., Hunkapiller, M. W., Hood, L. E., Devare, C. G., Robbins, K. C., Aaronson, S. A. and Antoniades, H. M (1983). Simian sarcoma virus onc gene, v- sis , is derived from the gene(s) encoding a platelet-derived growth factor. Science 221, 275-277.[Abstract/Free Full Text]

Dziadek, M (1978). Modulation of alpha-fetoprotein synthesis in the early post-implantation mouse embryo. J. Embryol. exp. Morph 46, 135-146.[Medline]

Dziadek, M. and Adamson, E (1978). Localization and synthesis of alphafetoprotein in post-implantation mouse embryos. J. Embryol. exp. Morph 43, 289-313.[Medline]

Ferns, G. A., Raines, E. W., Sprugel, K. H., Motani, A. S., Reidy, M. A. and Ross, R (1991). Inhibition of neointimal smooth muscle accumulation after angioplasty by an antibody to PDGF. Science 253, 1129-1132.[Abstract/Free Full Text]

Flanagan, J. G., Chan, D. C. and Leder, P (1991). Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant. Cell 64, 1025-1035.[Medline]

Gardner, R. L. and Rossant, J (1979). Investigation of the fate of 4.5 d post coitum mouse ICM cells by blastocyst injection. J. Embryol. exp. Morph 52, 141-152.[Medline]

Haub, O. and Goldfarb, M (1991). Expression of the fibroblast growth factor-5 gene in the mouse embryo. Development 112, 397-406.[Abstract]

Hebert, J. M., Boyle, M. and Martin, G. M (1991). mRNA localization studies suggest that murine FGF-5 plays a role in gastrulation. Development 112, 407-415.[Abstract]

Heldin, C-H., Betsholtz, C., Claesson-Welsh, L. and Westermark, B (1987). Subversion of growth regulatory pathways in malignant transformation. Biochim. Biophys. Acta 907, 219-244.[Medline]

Heldin, C-E. and Westermark, B (1989). Platelet derived growth factor: three isoforms and two receptor types. Trends Genet 5, 108-111.[Medline]

Hogan, B. L. M., Taylor, A. and Adamson, E (1981). Cell interactions modulate embryonal carcinoma cell differentiation into parietal or visceral endoderm. Nature 291, 235-237.[Medline]

Holmgren, L. Glaser, A., Pfeifer-Ohlsson, S. and Ohlsson, R (1991). Angiogenesis during human extraembryonic development involves the spatiotemporal control of PDGF ligand and receptor gene expression. Development 113, 749-754.[Abstract]

Keshet, E., Lyman, S. D., Williams, D. E., Anderson, D. M., Jenkins, N. A., Copeland, N. G. and Parada, L. F (1991). Embryonic RNA expression patterns of the c-kit receptor and its cognate ligand suggest multiple functional roles in mouse development. EMBO J 10, 2425-2435.[Medline]

Klagsbrun, M. and Baird, A (1991). A dual receptor system is required for basic fibroblast growth factor activity. Cell 67, 229-231.[Medline]

Kollar, E. J. and Fisher, S (1980). Tooth induction in chick epithelium. Science 207, 993-995.[Abstract/Free Full Text]

LaRochelle, W. J., May-Siroff, M., Robbins, K. C. and Aaronson, S. A (1991). A novel mechanism regulating growth factor association with the cell surface: identification of a PDGF retention domain. Genes Dev 5, 1191-1199.[Abstract/Free Full Text]

Lyons, K. M., Jones, C. M. and Hogan, B. L. M (1991). The DVR gene family in embryonic development. Trends Genet 7, 408-412.[Medline]

Massague, J (1991). A helping hand from proteoglycans. Current Biology 1, 117-119.

Motro, B., Van Der Kooy, D., Rossant, J., Reith, A. and Bernstein, A (1991). Contiguous patterns of c- kit and steel expression: analysis of mutations at the W and Sl loci. Development 113, 1207-1221.[Abstract]

Noble, M., Murray, K., Strooban, E. P., Waterfield, M. D. and Riddle, P (1988). Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type 2 astrocyte progenitor cell. Nature 333, 560-562.[Medline]

Niswander, L. and Martin, G. R (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.[Abstract]

Orr-Urtreger, A., Avivi, A., Zimmer, I., Givol, D., Yarden, Y. and Lonai, P (1990). Development expression of c- kit , a proto-oncogene encoded by the W locus. Development 109, 911-923.[Abstract/Free Full Text]

Orr-Urtreger, A., Givol, D., Yayon, A., Yarden, Y. and Lonai, P (1991). Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development 113, 1419-1434.[Abstract]

Orr-Urtreger, A., Bedford, M. T., Do, M-S, Eisenbach, L. and Lonai, P (1992). Developmental expression of thereceptor for the platelet derived growth factor, which is deleted in the embryonic lethal Patch mutation. Development 115, 289-303.[Abstract]

Raff, M. C., Lillien, L. E., Richardson, W. D., Burne, J. F. and Noble, M. D (1988). Platelet-derived growth factors from astrocytes drive the clock that times oligodendrocyte development in culture. Nature 333, 562-565.[Medline]

Ross, R., Raines, E. W. and Bowen-Pope, D. F (1986). The biology of platelet-derived growth factor. Cell 46, 155-169.[Medline]

Seifert, R. A., Hart, C. A., Phillips, P. E., Forstrom, J. W., Ross, R., Murray, M. J. and Bowen-Pope, D (1989). Two different subunits associate to make isoform-specific platelet-derived growth factor receptors. J. Biol. Chem 264, 8771-8778.[Abstract/Free Full Text]

Sherr, C. J., Rettenmier, C. W., Sacca, R., Roussel, M. F., Look, A. T. and Stanley, E. R (1985). The c- fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1. Cell 41, 665-676.[Medline]

Sporn, M. B. and Todaro, G. J (1980). Autocrine secretion and malignant transformation of cells. New Engl. J. Med 303, 878-880.[Medline]

Stephenson, D. A., Mercola, M., Anderson, E., Wang, C., Stiles, C. D., Bowen-Pope, D. F. and Chapman, V. M (1991). Platelet-derived growth factor-subunit gene (Pdgfra) is deleted in the mouse Patch (Ph) mutation. Proc. Natl. Acad. Sci. USA 88, 6-10.[Abstract/Free Full Text]

Todd, J. A., Bell, J. I. and McDevitt, H. O (1987). HLA-DQgene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature 329, 599-604.[Medline]

Ullrich, A. and Schlessinger, J (1990). Signal transduction by receptors with tyrosine kinase activity. Cell 61, 203-212.[Medline]

Waddington, C. H (1932). Experiments in the development of chick and duck embryos cultivatedin vitro. Philos. Trans. Roy. Soc. Lond. (Biol.) 221, 179-230.

Yamada, T., Placzek, M., Tanaka, H., Dodd, J. and Jessell, T. M (1991). Control of cell pattern in the developing nervous system: polarizing activity of the floor plate and the notochord. Cell 64, 635-647.[Medline]

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				J. Andrae, R. Gallini, and C. Betsholtz Role of platelet-derived growth factors in physiology and medicine Genes & Dev., May 15, 2008; 22(10): 1276 - 1312. [Abstract] [Full Text] [PDF]

				E. A. Pickett, G. S. Olsen, and M. D. Tallquist Disruption of PDGFR{alpha}-initiated PI3K activation and migration of somite derivatives leads to spina bifida Development, February 1, 2008; 135(3): 589 - 598. [Abstract] [Full Text] [PDF]

				S. F. Gilbert, G. Bender, E. Betters, M. Yin, and J. A. Cebra-Thomas The contribution of neural crest cells to the nuchal bone and plastron of the turtle shell Integr. Comp. Biol., September 1, 2007; 47(3): 401 - 408. [Abstract] [Full Text] [PDF]

				M. Itoi, N. Tsukamoto, H. Yoshida, and T. Amagai Mesenchymal cells are required for functional development of thymic epithelial cells Int. Immunol., August 1, 2007; 19(8): 953 - 964. [Abstract] [Full Text] [PDF]

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				Z. Gao, T. Sasaoka, T. Fujimori, T. Oya, Y. Ishii, H. Sabit, M. Kawaguchi, Y. Kurotaki, M. Naito, T. Wada, et al. Deletion of the PDGFR-{beta} Gene Affects Key Fibroblast Functions Important for Wound Healing J. Biol. Chem., March 11, 2005; 280(10): 9375 - 9389. [Abstract] [Full Text] [PDF]

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				A. Liebeskind, S. Srinivasan, D. Kaetzel, and M. Bruce Retinoic acid stimulates immature lung fibroblast growth via a PDGF-mediated autocrine mechanism Am J Physiol Lung Cell Mol Physiol, July 1, 2000; 279(1): L81 - L90. [Abstract] [Full Text] [PDF]

				A. Blixt, M. Mahlapuu, M. Aitola, M. Pelto-Huikko, S. Enerbäck, and P. Carlsson A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle Genes & Dev., January 15, 2000; 14(2): 245 - 254. [Abstract] [Full Text]

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				T Sun, D Jayatilake, G. Afink, P Ataliotis, M Nister, W. Richardson, and H. Smith A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth Development, January 11, 2000; 127(21): 4519 - 4529. [Abstract] [PDF]

				C.-H. Heldin and B. Westermark Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor Physiol Rev, October 1, 1999; 79(4): 1283 - 1316. [Abstract] [Full Text] [PDF]

				G. W. Hoyle, J. Li, J. B. Finkelstein, T. Eisenberg, J.-Y. Liu, J. A. Lasky, G. Athas, G. F. Morris, and A. R. Brody Emphysematous Lesions, Inflammation, and Fibrosis in the Lungs of Transgenic Mice Overexpressing Platelet-Derived Growth Factor Am. J. Pathol., June 1, 1999; 154(6): 1763 - 1775. [Abstract] [Full Text] [PDF]

				J. R. Crosby, K. A. Tappan, R. A. Seifert, and D. F. Bowen-Pope Chimera Analysis Reveals That Fibroblasts and Endothelial Cells Require Platelet-Derived Growth Factor Receptor� Expression for Participation in Reactive Connective Tissue Formation in Adults but Not during Development Am. J. Pathol., May 1, 1999; 154(5): 1315 - 1321. [Abstract] [Full Text] [PDF]

				L Karlsson, C Bondjers, and C Betsholtz Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle Development, January 6, 1999; 126(12): 2611 - 2621. [Abstract] [PDF]

				M Fruttiger, L Karlsson, A. Hall, A Abramsson, A. Calver, H Bostrom, K Willetts, C. Bertold, J. Heath, C Betsholtz, et al. Defective oligodendrocyte development and severe hypomyelination in PDGF-A knockout mice Development, January 2, 1999; 126(3): 457 - 467. [Abstract] [PDF]

				J. A. Epstein, B. Song, M. Lakkis, and C. Wang Tumor-Specific PAX3-FKHR Transcription Factor, but Not PAX3, Activates the Platelet-Derived Growth Factor Alpha Receptor Mol. Cell. Biol., July 1, 1998; 18(7): 4118 - 4130. [Abstract] [Full Text]

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				N. Takakura, H. Yoshida, Y. Ogura, H. Kataoka, S. Nishikawa, and S.-I. Nishikawa PDGFR{alpha} Expression During Mouse Embryogenesis: Immunolocalization Analyzed by Whole-mount Immunohistostaining Using the Monoclonal Anti-mouse PDGFR{alpha} Antibody APA5 J. Histochem. Cytochem., June 1, 1997; 45(6): 883 - 894. [Abstract] [Full Text] [PDF]

				P Lindahl, L Karlsson, M Hellstrom, S Gebre-Medhin, K Willetts, J. Heath, and C Betsholtz Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development Development, January 10, 1997; 124(20): 3943 - 3953. [Abstract] [PDF]

				P Soriano The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites Development, January 7, 1997; 124(14): 2691 - 2700. [Abstract] [PDF]

				JoanneM. Arrandale, A. Gore-Willse, S. Rocks, J.-M. Ren, J. Zhu, A. Davis, JamesN. Livingston, and DanielU. Rabin Insulin Signaling in Mice Expressing Reduced Levels of Syp J. Biol. Chem., August 30, 1996; 271(35): 21353 - 21358. [Abstract] [Full Text] [PDF]

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				P Ataliotis, K Symes, M. Chou, L Ho, and M Mercola PDGF signalling is required for gastrulation of Xenopus laevis Development, January 9, 1995; 121(9): 3099 - 3110. [Abstract] [PDF]