Molecular organization and embryonic expression of the hedgehog gene involved in cell-cell communication in segmental patterning of Drosophila

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Akam, M (1987). The molecular basis for metameric pattern in the Drosophila embryo. Development 101, 1-22.[Abstract]

Baker, N.E (1987). Molecular cloning of sequences from wingless , a segment polarity gene in Drosophila : the spatial distribution of a transcript in embryos. EMBO J 6, 1765-1773.[Medline]

Baker, N.E (1988). Embryonic and imaginal requirements for wingless , a segment-polarity gene in Drosophila. Dev. Biol 125, 96-108.[Medline]

Bejsovec, A. and Martinez-Arias, A (1991). Roles of wingless in patterning the larval epidermis of Drosophila. Development 113, 471-485.[Abstract]

Biggs, J., Tripoulas, N., Hersperger, E., Dearlof, C. and Shearn, A (1988). Analysis of the lethal interaction between the prune and Killer of prune mutations of Drosophila. Genes Dev 2, 1333-1343.[Abstract/Free Full Text]

Bopp, D., Murri, M., Baumgartner, S., Frigerio, G. and Noll, M (1986). Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila. Cell 48, 745-755.

Brown, N.H. and Kafatos, F.C (1988). Functional cDNA libraries from Drosophila embryos. J. Mol. Biol 203, 425-437.[Medline]

Chou, T.-B., Zachar, Z. and Bingham, P.M (1987). Developmental expression of a regulatory gene is programmed at the level of splicing. EMBO J 7, 4095-4104.

Cohen, S.M. and Jurgens, G (1990). Gap-like segmentation genes that mediate Drosophila head development. Nature 346, 482-485.[Medline]

DiNardo, S., Kuner, J.M., Theis, J. and O'Farrell, P.H (1985). Development of embryonic pattern in D. melanogaster as revealed by accumulation of the nuclear engrailed protein. Cell 43, 59-69.[Medline]

DiNardo, S., Sher, E., Heemskerek-Jongens, J., Kassis, J.A. and O'Farrell, P.H (1988). Two-tiered regulation of spatially patterned engrailed expression during Drosophila embryogenesis. Nature 332, 604-609.[Medline]

Driever, W. and Nusslein-Volhard, C (1988). The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 54, 95-104.[Medline]

Frigerio, G., Burri, M., Bopp, D., Baumgartner, S. and Noll, M (1988). Structure of segmentation gene paired and Drosophila PRD gene set as part of a gene network. Cell 47, 735-746.

Garber, R.L., Kuroiwa, A. and Gehring, W.J (1983). Genomic and971hedgehogexpression and sequencecDNA clones of the homeotic locus Antennapedia of Drosophila. EMBO J 2, 2027-2036.[Medline]

Hazelrigg, T., Levis, R. and Rubin, G (1984). Transformation of white locus DNA in Drosophila , dosage compensation, zeste interaction and position effects. Cell 36, 469-481.[Medline]

Hidalgo, A. and Ingham, P (1990). Cell patterning in the Drosophila segment: spatial regulation of the segment polarity gene, patched. Development 110, 291-301.[Abstract]

Hooper, J.E. and Scott, M.P (1989). The Drosophilapatched gene encodes a putative membrane protein required for segmental patterning. Cell 59, 751-765.[Medline]

Ingham, P.W., Howard, K.R. and Ish-Horowicz, D (1985). Transcription pattern of the Drosophila segmentation gene, hairy. Nature 318, 439-445.

Ingham, P (1988). The molecular genetics of embryonic pattern formation in Drosophila. Nature 335, 25-34.[Medline]

Ingham, P.W., Taylor, A.M. and Nakano, Y (1991). Role of the Drosophilapatched gene in positional signalling. Nature 353, 184-186.[Medline]

Klingensmith, J., Noll, E. and Perrimon, N (1989). The segment polarity phenotype of Drosophila involves differential tendencies toward transformation and cell death. Dev. Biol 134, 130-145.[Medline]

Kornberg, T., Siden, I., O'Farrell, P. and Simon, M (1985). The engrailed locus of Drosophila : in situ localization of transcripts reveals compartment-specific expression. Cell 40, 45-53.[Medline]

Kuroiwa, A., Hafen, E. and Gehring, W.J (1984). Cloning and transcriptional analysis of the segmentation gene fushi tarazu of Drosophila. Cell 37, 825-831.[Medline]

Kyte, J. and Doolittle, R.F (1982). A simple method for displaying the hydropathic character of a protein. J. Mol. Biol 157, 133-148.[Medline]

Levis, R., Hazelrigg, T. and Rubin, G.M (1985). Effects of genomic position on the expression of transduced copies of the white gene of Drosophila. Science 229, 558-561.[Abstract/Free Full Text]

Limbourg-Bouchon, B., Busson, D. and Lamour-Isnard, C (1991). Interaction between fused , a segment-polarity gene in Drosophila , and other segmentation genes. Development 112, 417-429.[Abstract]

Martinez-Arias, A (1985). The development of fused-embryos of Drosophilamelanogaster. J. Embryol. Exp. Morph 87, 99-114.[Medline]

Martinez-Arias, A. and Lawrence, P.A (1985). Parasegments and compartments in the Drosophila embryo. Nature 313, 639-642.[Medline]

Martinez-Arias, A., Baker, N.E. and Ingham, P.W (1988). Role of segment polarity genes in the definition and maintenance of cell states in the Drosophila embryo. Development 103, 157-170.[Abstract]

McCrea, P.D., Turck, C.W. and Gumbinger, B (1991). A homolog of the armadillo protein in Drosophila (plakoglobin) associated with E-cadherin. Science 254, 1259-1361.

Mohler, J (1988). Requirements for hedgehog , a segmental polarity gene, in patterning larval and adult cuticle of Drosophila. Genetics 120, 1061-1072.[Abstract/Free Full Text]

Mohler, J., Vani, K., Leung, S. and Epstein, A (1991). Segmentally restricted, cephalic expression of a leucine zipper gene during Drosophila embryogenesis. Mech. Dev 34, 3-10.[Medline]

Mohler, J., Weiss, N., Murli, S., Mohammadi, S., Vani, K., Vasilakis, G., Song, C.H., Epstein, A., Kuang, T., English, J. and Cherdak, D (1992). The embryonically active gene, unkempt , of Drosophila encodes a Cys3 His finger protein. Genetics 131, 377-388.[Abstract]

Mount, S.M (1982). A catalog of splice junction sequences. Nucleic Acids Res 10, 459-472.[Abstract/Free Full Text]

Orenic, T.V., Slusarski, D.C., Kroll, K.L. and Holmgren, R.A (1990). Cloning and characterization of the segment polarity gene cubitus interruptus dominant of Drosophila. Genes Dev 4, 1053-1067.[Abstract/Free Full Text]

Pankratz, M.J. and J\212ckle, H (1990). Making stripes in the Drosophila embryo. Trends Genet 6, 287-292.[Medline]

Perkins, K., Admon, A., Patel, N. and Tjian, R (1989). The Drosophila Fos-related AP-1 protein is a developmentally regulated transcription factor. Genes Dev 4, 822-834.[Abstract/Free Full Text]

Perrimon, N. and Mahowald, A.P (1987). Multiple functions of segment polarity genes in Drosophila. Dev. Biol 119, 587-600.[Medline]

Perrimon, N., Engstrom, L. and Mahowald, A.P (1989). Zygotic lethals with specific maternal effect phenotypes in Drosophila melanogaster . I. Loci on the X chromosome. Genetics 121, 333-352.[Abstract/Free Full Text]

Peifer, M. and Wieschaus, E (1990). The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin. Cell 63, 1167-1178.[Medline]

Pirrotta, V., Hadfield, C. and Pretorius, G.M.J (1983). Microdissection and cloning of the white gene and the 3B1-3C2 region of the Drosophila X chromosome. EMBO J 2, 927-934.[Medline]

Pirrotta, V. and Br\232ckl, C (1984). Transcription of the Drosophilawhite locus and some of its mutants. EMBO J 3, 563-568.[Medline]

Preat, T., Therond, P., Lamour-Isnard, C., Limbourg-Bouchon, B., Tricare, H., Erk, I., Mariol, M.-C. and Busson, D (1990). A putative serine/threonine kinase encoded by the segment polarity gene fused of Drosophila. Nature 347, 87-89.[Medline]

Rao, J.K.M. and Argos, P (1986). A conformational preference parameter to predict helices in integral membrane proteins. Biochim. Biophys. Acta 869, 197-214.[Medline]

Riggleman, B., Schedl, P. and Wieschaus, E (1990). Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless. Cell 63, 549-560.[Medline]

Ruskin, B., Krainer, A.R., Maniatis, T. and Green, M.R (1984). Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro. Cell 38, 317-331.[Medline]

Scott, M.P., Weiner, A.J., Hazelrigg, T.I., Polisky, B.A., Pirrotta, V., Scalenge, F. and Kaufman, T.C (1983). The molecular organization of the Antennapedia locus of Drosophila. Cell 35, 763-776.[Medline]

Shermoen, A.W. and O'Farrell, P.H (1991). Progression of the cell cycle through mitosis leads to abortion of nascent transcripts. Cell 67, 303-310.[Medline]

Seigfried, E., Perkins, L.A., Capaci, T.M. and Perrimon, N (1990). Putative protein kinase product of the Drosophila segment polarity gene zeste-white3. Nature 345, 825-829.[Medline]

Tautz, D. and Pfeifle, C (1989). A non-radioactive in situ hybridization method for the localization of specific RNAs. Chromosoma 98, 81-85.[Medline]

van Den Heuvel, M., Nusse, R., Johnston, P. and Lawrence, P.A (1989). Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell 59, 739-749.[Medline]

Wang, C. and Lehmann, R (1991). Nanos is the localized posterior determinant in Drosophila. Cell 66, 637-647.[Medline]

Wiener, A.J., Scott, M.P. and Kaufman, T.C (1984). A molecular analysis of fushi tarazu , a gene in Drosophilamelanogaster that encodes a product affecting embryonic segment number and cell fate. Cell 37, 843-851.[Medline]

Wilson, C., Pearson, R.K., Bellen, H.J., O'Kane, C.J., Grossniklaus, U. and Gehring, W.J (1989). P-element-mediated enhancer detection: an efficient method for isolating and characterizing developmentally regulated genes in Drosophila. Genes Dev 3, 1301-1313.[Abstract/Free Full Text]

Zachar, Z., Davidson, D., Garza, D. and Bingham, P.M (1985). A detailed developmental and structural study of the transcriptional effects of insertion of the copia transposon into the white locus of Drosophila melanogaster. Genetics 111, 495-515.[Abstract/Free Full Text]

Zachar, Z., Chou, T.-B. and Bingham, P.M (1987). Evidence that a regulatory gene autoregulates splicing of its transcript. EMBO J 7, 4105-4111.

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				M. Kango-Singh, R. Nolo, C. Tao, P. Verstreken, P. R. Hiesinger, H. J. Bellen, and G. Halder Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila Development, March 14, 2003; 129(24): 5719 - 5730. [Abstract] [Full Text] [PDF]

				K. E. Nybakken, C. W. Turck, D. J. Robbins, and J. M. Bishop Hedgehog-stimulated Phosphorylation of the Kinesin-related Protein Costal2 Is Mediated by the Serine/Threonine Kinase Fused J. Biol. Chem., June 28, 2002; 277(27): 24638 - 24647. [Abstract] [Full Text] [PDF]

				M. Ruiz-Gomez, N. Coutts, M. L. Suster, M. Landgraf, and M. Bate myoblasts incompetent encodes a zinc finger transcription factor required to specify fusion-competent myoblasts in Drosophila Development, January 1, 2002; 129(1): 133 - 141. [Abstract] [Full Text] [PDF]

				H. Duan, J. B. Skeath, and H. T. Nguyen Drosophila Lame duck, a novel member of the Gli superfamily, acts as a key regulator of myogenesis by controlling fusion-competent myoblast development Development, November 15, 2001; 128(22): 4489 - 4500. [Abstract] [Full Text] [PDF]

				F. Pierucci-Alves, A. M. Clark, and L. D. Russell A Developmental Study of the Desert Hedgehog-Null Mouse Testis Biol Reprod, November 1, 2001; 65(5): 1392 - 1402. [Abstract] [Full Text] [PDF]

				N. Haines and M. van den Heuvel A Directed Mutagenesis Screen in Drosophila melanogaster Reveals New Mutants That Influence hedgehog Signaling Genetics, December 1, 2000; 156(4): 1777 - 1785. [Abstract] [Full Text]

				F. Chanut, A. Luk, and U. Heberlein A Screen for Dominant Modifiers of roDom, a Mutation That Disrupts Morphogenetic Furrow Progression in Drosophila, Identifies Groucho and Hairless as Regulators of atonal Expression Genetics, November 1, 2000; 156(3): 1203 - 1217. [Abstract] [Full Text]

				A Gallet, C Angelats, S Kerridge, and P. Therond Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila Development, January 12, 2000; 127(24): 5509 - 5522. [Abstract] [PDF]

				S. Hakeda, S. Endo, and K. Saigo Requirements of Kettin, a Giant Muscle Protein Highly Conserved in Overall Structure in Evolution, for Normal Muscle Function, Viability, and Flight Activity of Drosophila J. Cell Biol., January 10, 2000; 148(1): 101 - 114. [Abstract] [Full Text] [PDF]

				T. R. Breen Mutant Alleles of the Drosophila trithorax Gene Produce Common and Unusual Homeotic and Other Developmental Phenotypes Genetics, May 1, 1999; 152(1): 319 - 344. [Abstract] [Full Text]

				P. Therond, B Limbourg Bouchon, A Gallet, F Dussilol, T Pietri, M van den Heuvel, and H Tricoire Differential requirements of the fused kinase for hedgehog signalling in the Drosophila embryo Development, January 9, 1999; 126(18): 4039 - 4051. [Abstract] [PDF]

				U Gritzan, V Hatini, and S DiNardo Mutual antagonism between signals secreted by adjacent wingless and engrailed cells leads to specification of complementary regions of the Drosophila parasegment Development, January 9, 1999; 126(18): 4107 - 4115. [Abstract] [PDF]

				Y. Chen, N. Gallaher, R. H. Goodman, and S. M. Smolik Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus PNAS, March 3, 1998; 95(5): 2349 - 2354. [Abstract] [Full Text] [PDF]

				Z Huang and S Kunes Signals transmitted along retinal axons in Drosophila: Hedgehog signal reception and the cell circuitry of lamina cartridge assembly Development, January 10, 1998; 125(19): 3753 - 3764. [Abstract] [PDF]

				N. Miao, M. Wang, J. A. Ott, J. S. D'Alessandro, T. M. Woolf, D. A. Bumcrot, N. K. Mahanthappa, and K. Pang Sonic Hedgehog Promotes the Survival of Specific CNS Neuron Populations and Protects These Cells from Toxic Insult In Vitro J. Neurosci., August 1, 1997; 17(15): 5891 - 5899. [Abstract] [Full Text] [PDF]

				T. Von Ohlen, D. Lessing, R. Nusse, and J. E. Hooper Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding�protein PNAS, March 18, 1997; 94(6): 2404 - 2409. [Abstract] [Full Text] [PDF]

				A Kopp, M. Muskavitch, and I Duncan The roles of hedgehog and engrailed in patterning adult abdominal segments of Drosophila Development, January 10, 1997; 124(19): 3703 - 3714. [Abstract] [PDF]

				A Kopp and I Duncan Control of cell fate and polarity in the adult abdominal segments of Drosophila by optomotor-blind Development, January 10, 1997; 124(19): 3715 - 3726. [Abstract] [PDF]

				S. Blair and A Ralston Smoothened-mediated Hedgehog signalling is required for the maintenance of the anterior-posterior lineage restriction in the developing wing of Drosophila Development, January 10, 1997; 124(20): 4053 - 4063. [Abstract] [PDF]

				J. McDonald and C. Doe Establishing neuroblast-specific gene expression in the Drosophila CNS: huckebein is activated by Wingless and Hedgehog and repressed by Engrailed and Gooseberry Development, January 3, 1997; 124(5): 1079 - 1087. [Abstract] [PDF]

				J Hepker, Q. Wang, C. Motzny, R Holmgren, and T. Orenic Drosophila cubitus interruptus forms a negative feedback loop with patched and regulates expression of Hedgehog target genes Development, January 1, 1997; 124(2): 549 - 558. [Abstract] [PDF]