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A. Kunisato, S. Chiba, E. Nakagami-Yamaguchi, K. Kumano, T. Saito, S. Masuda, T. Yamaguchi, M. Osawa, R. Kageyama, H. Nakauchi, et al. HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo Blood, March 1, 2003; 101(5): 1777 - 1783. [Abstract] [Full Text] [PDF] |
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B. Varnum-Finney, C. Brashem-Stein, and I. D. Bernstein Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability Blood, March 1, 2003; 101(5): 1784 - 1789. [Abstract] [Full Text] [PDF] |
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K. Fujimori, Y. Fujitani, K. Kadoyama, H. Kumanogoh, K. Ishikawa, and Y. Urade Regulation of Lipocalin-type Prostaglandin D Synthase Gene Expression by Hes-1 through E-box and Interleukin-1beta via Two NF-kappa B Elements in Rat Leptomeningeal Cells J. Biol. Chem., February 14, 2003; 278(8): 6018 - 6026. [Abstract] [Full Text] [PDF] |
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M. Dorsch, G. Zheng, D. Yowe, P. Rao, Y. Wang, Q. Shen, C. Murphy, X. Xiong, Q. Shi, J.-C. Gutierrez-Ramos, et al. Ectopic expression of Delta4 impairs hematopoietic development and leads to lymphoproliferative disease Blood, August 28, 2002; 100(6): 2046 - 2055. [Abstract] [Full Text] [PDF] |
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V. Sriuranpong, M. W. Borges, C. L. Strock, E. K. Nakakura, D. N. Watkins, C. M. Blaumueller, B. D. Nelkin, and D. W. Ball Notch Signaling Induces Rapid Degradation of Achaete-Scute Homolog 1 Mol. Cell. Biol., May 1, 2002; 22(9): 3129 - 3139. [Abstract] [Full Text] [PDF] |
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S. Stier, T. Cheng, D. Dombkowski, N. Carlesso, and D. T. Scadden Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome Blood, April 1, 2002; 99(7): 2369 - 2378. [Abstract] [Full Text] [PDF] |
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S. L. Dunwoodie, M. Clements, D. B. Sparrow, X. Sa, R. A. Conlon, and R. S. P. Beddington Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm Development, January 4, 2002; 129(7): 1795 - 1806. [Abstract] [Full Text] [PDF] |
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K. Kumano, S. Chiba, K. Shimizu, T. Yamagata, N. Hosoya, T. Saito, T. Takahashi, Y. Hamada, and H. Hirai Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression Blood, December 1, 2001; 98(12): 3283 - 3289. [Abstract] [Full Text] [PDF] |
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K. Ohishi, B. Varnum-Finney, R. E. Serda, C. Anasetti, and I. D. Bernstein The Notch ligand, Delta-1, inhibits the differentiation of monocytes into macrophages but permits their differentiation into dendritic cells Blood, September 1, 2001; 98(5): 1402 - 1407. [Abstract] [Full Text] [PDF] |
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T. Mizutani, Y. Taniguchi, T. Aoki, N. Hashimoto, and T. Honjo Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members PNAS, July 13, 2001; (2001) 161269998. [Abstract] [Full Text] [PDF] |
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A. V. Gordadze, R. Peng, J. Tan, G. Liu, R. Sutton, B. Kempkes, G. W. Bornkamm, and P. D. Ling Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus J. Virol., July 1, 2001; 75(13): 5899 - 5912. [Abstract] [Full Text] [PDF] |
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J. Wang, L. Shelly, L. Miele, R. Boykins, M. A. Norcross, and E. Guan Human Notch-1 Inhibits NF-{{kappa}}B Activity in the Nucleus Through a Direct Interaction Involving a Novel Domain J. Immunol., July 1, 2001; 167(1): 289 - 295. [Abstract] [Full Text] [PDF] |
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K. W. Makar, D. Ulgiati, J. Hagman, and V. M. Holers A site in the complement receptor 2 (CR2/CD21) silencer is necessary for lineage specific transcriptional regulation Int. Immunol., May 1, 2001; 13(5): 657 - 664. [Abstract] [Full Text] [PDF] |
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H. Höfelmayr, L. J. Strobl, G. Marschall, G. W. Bornkamm, and U. Zimber-Strobl Activated Notch1 Can Transiently Substitute for EBNA2 in the Maintenance of Proliferation of LMP1-Expressing Immortalized B Cells J. Virol., March 1, 2001; 75(5): 2033 - 2040. [Abstract] [Full Text] |
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T. Morimura, S. Miyatani, D. Kitamura, and R. Goitsuka Notch Signaling Suppresses IgH Gene Expression in Chicken B Cells: Implication in Spatially Restricted Expression of Serrate2/Notch1 in the Bursa of Fabricius J. Immunol., March 1, 2001; 166(5): 3277 - 3283. [Abstract] [Full Text] [PDF] |
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K. Koizumi, M Nakajima, S Yuasa, Y Saga, T Sakai, T Kuriyama, T Shirasawa, and H Koseki The role of presenilin 1 during somite segmentation Development, January 4, 2001; 128(8): 1391 - 1402. [Abstract] [PDF] |
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B McCright, X Gao, L Shen, J Lozier, Y Lan, M Maguire, D Herzlinger, G Weinmaster, R Jiang, and T Gridley Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation Development, January 2, 2001; 128(4): 491 - 502. [Abstract] [PDF] |
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K. Shimizu, S. Chiba, N. Hosoya, K. Kumano, T. Saito, M. Kurokawa, Y. Kanda, Y. Hamada, and H. Hirai Binding of Delta1, Jagged1, and Jagged2 to Notch2 Rapidly Induces Cleavage, Nuclear Translocation, and Hyperphosphorylation of Notch2 Mol. Cell. Biol., September 15, 2000; 20(18): 6913 - 6922. [Abstract] [Full Text] |
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S. Tsai, J. Fero, and S. Bartelmez Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact Blood, August 1, 2000; 96(3): 950 - 957. [Abstract] [Full Text] [PDF] |
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S. Jeffries and A. J. Capobianco Neoplastic Transformation by Notch Requires Nuclear Localization Mol. Cell. Biol., June 1, 2000; 20(11): 3928 - 3941. [Abstract] [Full Text] |
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J. R. Shutter, S. Scully, W. Fan, W. G. Richards, J. Kitajewski, G. A. Deblandre, C. R. Kintner, and K. L. Stark Dll4, a novel Notch ligand expressed in arterial endothelium Genes & Dev., June 1, 2000; 14(11): 1313 - 1318. [Abstract] [Full Text] |
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K. Ohishi, B. Varnum-Finney, D. Flowers, C. Anasetti, D. Myerson, and I. D. Bernstein Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1 Blood, May 1, 2000; 95(9): 2847 - 2854. [Abstract] [Full Text] [PDF] |
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F. Radtke, I. Ferrero, A. Wilson, R. Lees, M. Aguet, and H. R. MacDonald Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells J. Exp. Med., April 3, 2000; 191(7): 1085 - 1094. [Abstract] [Full Text] [PDF] |
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W. Han, Q. Ye, and M. A. S. Moore A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells Blood, March 1, 2000; 95(5): 1616 - 1625. [Abstract] [Full Text] [PDF] |
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L. J. Strobl, H. Höfelmayr, G. Marschall, M. Brielmeier, G. W. Bornkamm, and U. Zimber-Strobl Activated Notch1 Modulates Gene Expression in B Cells Similarly to Epstein-Barr Viral Nuclear Antigen 2 J. Virol., February 15, 2000; 74(4): 1727 - 1735. [Abstract] [Full Text] |
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G. F. Hoyne, I. Le Roux, M. Corsin-Jimenez, K. Tan, J. Dunne, L. M. G. Forsyth, M. J. Dallman, M. J. Owen, D. Ish-Horowicz, and J. R. Lamb Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4+ T cells Int. Immunol., February 1, 2000; 12(2): 177 - 185. [Abstract] [Full Text] [PDF] |
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M. Rones, K. McLaughlin, M Raffin, and M Mercola Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis Development, January 9, 2000; 127(17): 3865 - 3876. [Abstract] [PDF] |
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T Ito, N Udaka, T Yazawa, K Okudela, H Hayashi, T Sudo, F Guillemot, R Kageyama, and H Kitamura Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium Development, January 9, 2000; 127(18): 3913 - 3921. [Abstract] [PDF] |
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A Zine, T. Van De Water, and F de Ribaupierre Notch signaling regulates the pattern of auditory hair cell differentiation in mammals Development, January 8, 2000; 127(15): 3373 - 3383. [Abstract] [PDF] |
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M. Lin, C Leimeister, M Gessler, and R Kopan Activation of the Notch pathway in the hair cortex leads to aberrant differentiation of the adjacent hair-shaft layers Development, January 6, 2000; 127(11): 2421 - 2432. [Abstract] [PDF] |
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K. Shimizu, S. Chiba, K. Kumano, N. Hosoya, T. Takahashi, Y. Kanda, Y. Hamada, Y. Yazaki, and H. Hirai Mouse Jagged1 Physically Interacts with Notch2 and Other Notch Receptors. ASSESSMENT BY QUANTITATIVE METHODS J. Biol. Chem., November 12, 1999; 274(46): 32961 - 32969. [Abstract] [Full Text] [PDF] |
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M. P. Felli, M. Maroder, T. A. Mitsiadis, A. F. Campese, D. Bellavia, A. Vacca, R. S. Mann, L. Frati, U. Lendahl, A. Gulino, et al. Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand–receptor interactions in intrathymic T cell development Int. Immunol., July 1, 1999; 11(7): 1017 - 1025. [Abstract] [Full Text] [PDF] |
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J. Wilson-Rawls, J. D. Molkentin, B. L. Black, and E. N. Olson Activated Notch Inhibits Myogenic Activity of the MADS-Box Transcription Factor Myocyte Enhancer Factor 2C Mol. Cell. Biol., April 1, 1999; 19(4): 2853 - 2862. [Abstract] [Full Text] [PDF] |
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N. Carlesso, J. C. Aster, J. Sklar, and D. T. Scadden Notch1-Induced Delay of Human Hematopoietic Progenitor Cell Differentiation Is Associated With Altered Cell Cycle Kinetics Blood, February 1, 1999; 93(3): 838 - 848. [Abstract] [Full Text] [PDF] |
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Y Hamada, Y Kadokawa, M Okabe, M Ikawa, J. Coleman, and Y Tsujimoto Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality Development, January 8, 1999; 126(15): 3415 - 3424. [Abstract] [PDF] |
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W. PEAR, Z. TANG, S. DEROCCO, D. ALLMAN, R. HARDY, J. PUI, L. XU, F. KARNELL, J. ASTER, and T. KADESCH Consequences of Notch-mediated Inhibition of the Transcription Factor E47 Cold Spring Harb Symp Quant Biol, January 1, 1999; 64(0): 33 - 38. [Abstract] [PDF] |
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H. K. Kim and G. Siu The Notch Pathway Intermediate HES-1 Silences CD4 Gene Expression Mol. Cell. Biol., December 1, 1998; 18(12): 7166 - 7175. [Abstract] [Full Text] |
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S. Jarriault, O. Le Bail, E. Hirsinger, O. Pourquié, F. Logeat, C. F. Strong, C. Brou, N. G. Seidah, and A. Israël Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation Mol. Cell. Biol., December 1, 1998; 18(12): 7423 - 7431. [Abstract] [Full Text] |
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S. V. Ivanov, I. Kuzmin, M.-H. Wei, S. Pack, L. Geil, B. E. Johnson, E. J. Stanbridge, and M. I. Lerman Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes PNAS, October 13, 1998; 95(21): 12596 - 12601. [Abstract] [Full Text] [PDF] |
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P. Jones, G. May, L. Healy, J. Brown, G. Hoyne, S. Delassus, and T. Enver Stromal Expression of Jagged 1 Promotes Colony Formation by Fetal Hematopoietic Progenitor Cells Blood, September 1, 1998; 92(5): 1505 - 1511. [Abstract] [Full Text] [PDF] |
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S. K. Halder, H. Takemori, O. Hatano, Y. Nonaka, A. Wada, and M. Okamoto Cloning of a Membrane-Spanning Protein with Epidermal Growth Factor-Like Repeat Motifs from Adrenal Glomerulosa Cells Endocrinology, July 1, 1998; 139(7): 3316 - 3328. [Abstract] [Full Text] [PDF] |
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B. Varnum-Finney, L. E. Purton, M. Yu, C. Brashem-Stein, D. Flowers, S. Staats, K. A. Moore, I. Le Roux, R. Mann, G. Gray, et al. The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells Blood, June 1, 1998; 91(11): 4084 - 4091. [Abstract] [Full Text] [PDF] |
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A. Bigas, D. I. K. Martin, and L. A. Milner Notch1 and Notch2 Inhibit Myeloid Differentiation in Response to Different Cytokines Mol. Cell. Biol., April 1, 1998; 18(4): 2324 - 2333. [Abstract] [Full Text] |
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Z.-Z. Bao and C. L. Cepko The Expression and Function of Notch Pathway Genes in the Developing Rat Eye J. Neurosci., February 15, 1997; 17(4): 1425 - 1434. [Abstract] [Full Text] [PDF] |
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W Zhong, M. Jiang, G Weinmaster, L. Jan, and Y. Jan Differential expression of mammalian Numb, Numblike and Notch1 suggests distinct roles during mouse cortical neurogenesis Development, January 5, 1997; 124(10): 1887 - 1897. [Abstract] [PDF] |
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T. Mitsiadis, D Henrique, I Thesleff, and U Lendahl Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4 Development, January 4, 1997; 124(8): 1473 - 1483. [Abstract] [PDF] |
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J. de la Pompa, A Wakeham, K. Correia, E Samper, S Brown, R. Aguilera, T Nakano, T Honjo, T. Mak, J Rossant, et al. Conservation of the Notch signalling pathway in mammalian neurogenesis Development, January 3, 1997; 124(6): 1139 - 1148. [Abstract] [PDF] |
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M. K. Lee, H. H. Slunt, L. J. Martin, G. Thinakaran, G. Kim, S. E. Gandy, M. Seeger, E. Koo, D. L. Price, and S. S. Sisodia Expression of Presenilin 1 and 2 (PS1 and PS2) in Human and Murine Tissues J. Neurosci., December 1, 1996; 16(23): 7513 - 7525. [Abstract] [Full Text] [PDF] |
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L. A. Milner, A. Bigas, R. Kopan, C. Brashem-Stein, I. D. Bernstein, and D. I. K. Martin Inhibition of granulocytic differentiation by mNotch1 PNAS, November 12, 1996; 93(23): 13014 - 13019. [Abstract] [Full Text] [PDF] |
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L Girard, Z Hanna, N Beaulieu, C D Hoemann, C Simard, C A Kozak, and P Jolicoeur Frequent provirus insertional mutagenesis of Notch1 in thymomas of MMTVD/myc transgenic mice suggests a collaboration of c-myc and Notch1 for oncogenesis. Genes & Dev., August 1, 1996; 10(15): 1930 - 1944. [Abstract] [PDF] |
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H Uyttendaele, G Marazzi, G Wu, Q Yan, D Sassoon, and J Kitajewski Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene Development, July 1, 1996; 122(7): 2251 - 2259. [Abstract] [PDF] |
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C Shawber, D Nofziger, J. Hsieh, C Lindsell, O Bogler, D Hayward, and G Weinmaster Notch signaling inhibits muscle cell differentiation through a CBF1-independent pathway Development, January 12, 1996; 122(12): 3765 - 3773. [Abstract] [PDF] |
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D. Raible and J. Eisen Regulative interactions in zebrafish neural crest Development, January 2, 1996; 122(2): 501 - 507. [Abstract] [PDF] |
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S Artavanis-Tsakonas, K Matsuno, and M. Fortini Notch signaling Science, April 14, 1995; 268(5208): 225 - 232. [Abstract] [PDF] |
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C. Austin, D. Feldman, J. Ida, and C. Cepko Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch Development, January 11, 1995; 121(11): 3637 - 3650. [Abstract] [PDF] |
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C Oka, T Nakano, A Wakeham, J. de la Pompa, C Mori, T Sakai, S Okazaki, M Kawaichi, K Shiota, T. Mak, et al. Disruption of the mouse RBP-J kappa gene results in early embryonic death Development, January 10, 1995; 121(10): 3291 - 3301. [Abstract] [PDF] |
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B Bettenhausen, M Hrabe de Angelis, D Simon, J. Guenet, and A Gossler Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila Delta Development, January 8, 1995; 121(8): 2407 - 2418. [Abstract] [PDF] |
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R. Conlon, A. Reaume, and J Rossant Notch1 is required for the coordinate segmentation of somites Development, January 5, 1995; 121(5): 1533 - 1545. [Abstract] [PDF] |
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A. Newman, J. White, and P. Sternberg The Caenorhabditis elegans lin-12 gene mediates induction of ventral uterine specialization by the anchor cell Development, January 2, 1995; 121(2): 263 - 271. [Abstract] [PDF] |
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R. Kopan, J. S. Nye, and H. Weintraub The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD Development, September 1, 1994; 120(9): 2385 - 2396. [Abstract] [PDF] |
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J. S. Nye, R. Kopan, and R. Axel An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells Development, September 1, 1994; 120(9): 2421 - 2430. [Abstract] [PDF] |
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P J Swiatek, C E Lindsell, F F del Amo, G Weinmaster, and T Gridley Notch1 is essential for postimplantation development in mice. Genes & Dev., March 15, 1994; 8(6): 707 - 719. [Abstract] [PDF] |
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R. Diederich, K Matsuno, H Hing, and S Artavanis-Tsakonas Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway Development, January 3, 1994; 120(3): 473 - 481. [Abstract] [PDF] |
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J. Aster, W. Pear, R. Hasserjian, H. Erba, F. Davi, B. Luo, M. Scott, D. Baltimore, and J. Sklar Functional Analysis of the TAN-1 Gene, a Human Homolog of Drosophila Notch Cold Spring Harb Symp Quant Biol, January 1, 1994; 59(0): 125 - 136. [Abstract] [PDF] |
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K. Fitzgerald, H. A. Wilkinson, and I. Greenwald glp-1 can substitute for lin-12 in specifying cell fate decisions in Caenorhabditis elegans Development, December 1, 1993; 119(4): 1019 - 1027. [Abstract] [PDF] |
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T Lieber, S Kidd, E Alcamo, V Corbin, and M W Young Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes & Dev., October 1, 1993; 7(10): 1949 - 1965. [Abstract] [PDF] |
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K. Shimizu, S. Chiba, T. Saito, K. Kumano, T. Takahashi, and H. Hirai Manic Fringe and Lunatic Fringe Modify Different Sites of the Notch2 Extracellular Region, Resulting in Different Signaling Modulation J. Biol. Chem., July 6, 2001; 276(28): 25753 - 25758. [Abstract] [Full Text] [PDF] |
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J. Ingles-Esteve, L. Espinosa, L. A. Milner, C. Caelles, and A. Bigas Phosphorylation of Ser2078 Modulates the Notch2 Function in 32D Cell Differentiation J. Biol. Chem., November 21, 2001; 276(48): 44873 - 44880. [Abstract] [Full Text] [PDF] |
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T. Mizutani, Y. Taniguchi, T. Aoki, N. Hashimoto, and T. Honjo Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members PNAS, July 31, 2001; 98(16): 9026 - 9031. [Abstract] [Full Text] [PDF] |
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