Multiple extracellular signals are required for long-term oligodendrocyte survival

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Arakawa, Y., Sendtner, M. and Thoenen, H (1990). Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparision with other neurotrophic factors and cytokines. J. Neurosci 10, 3507-3515.[Abstract]

Barbin, G., Manthorpe, M. and Varon, S (1984). Purification of the chick eye ciliary neurotrophic factor. J. Neurochem 43, 1468-1478.[Medline]

Barde, Y. A (1989). Trophic factors and neuronal survival. Neuron 2, 1525-34.[Medline]

Barde, Y. A (1990). The nerve growth family. Prog. Growth Factor Res 2, 237-48.[Medline]

Barres, B. A. and Raff M. C (1993). Proliferation of oligodendrocyte precursor cells depends on electrical activity in axons. Nature 361, 258-260.[Medline]

Cohen, J. J (1991). Programmed cell death in the immune system. Adv. Immunol 50, 55-85.[Medline]

Dohrmann, U., Edgar, D. and Thoenen, H (1986). Muscle-derived factors that support survival and promote fiber outgrowth from embryonic chick spinal motor neurons in culture. Dev. Biol 118, 209-221.[Medline]

Gratzner, H. G (1982). Monoclonal antibody to 5-bromo-and 5-iododeoxyuridine:a new reagent for detection of DNA replication. Science 318, 474-475.

Huber, J., Thoenen, H. and Sendtner, M (1992). Characterisation of a high and low affinity receptor for CNTF. Soc. Neurosci. Abstr._Fb_276.1. Hughes, S. M., Lillien, L. E., Raff, M. C., Rohrer, H. and Sendtner,_Fb_M. (1988). Ciliary neurotrophic factor induces type-2 astrocyte differentiation in culture. Nature 335, 70-73.

Levi-Montalcini, R (1987). The nerve growth factor: 35 years later. EMBO J 6, 1145-1154.[Medline]

Levine, J. M (1989). Neuronal influences in glial progenitor cell development. Neuron 3, 103-113.[Medline]

Louis, J. C., Magal, E., Takayama, S. and Varon, S (1992). Differential effects of CNTF, LIF, and IL-6 on oligodendrocyte-type-2 astrocyte progenitor cells. Soc. Neurosci. Abstr._Fb_467.10. Louis, J. C., Magal, E., Takayama, S. and Varon, S. (1993).CNTF protection of oligodendrocytes against natural and tumor necrosis factor-induced death. Science 259, 689-692.

Martin, D. P., Schmidt, R. E., DiStefano, P. S., Lowry, O. H., Carter, J. G. and Johnson, E. M., Jr (1988). Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J. Cell Biol 106, 829-844.[Abstract/Free Full Text]

Mosmann, T (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Meth 65, 55-63.[Medline]

Patterson, P. H (1992). The emerging neuropoietic cytokine family. Curr. Opin. Neurobiol 2, 94-97.[Medline]

Pruss, R (1979). Thy-1 antigen on astrocytes in long-term cultures of rat central nervous system. Nature 303, 390-396.

Raff, M. C (1992). Social controls on cell survival and death: an extreme view. Nature 356, 397-400.[Medline]

Rudge, J. S., Manthorpe, M. and Varon, S (1985). The output of neuronotrophic and neurite-promoting agents from rat brain astroglial cells: a microculture method for screening potential regulatory molecules. Dev. Brain Res 19, 161-172.

Van Snick, J (1990). Interleukin-6: An overview. Ann. Rev. Immunol 8, 253-278.[Medline]

Yamamori, T (1991). Localization of cholinergic differentiation factor/leukemia inhibitory factor mRNA in the rat brain and peripheral tissues. Proc. Natl. Acad. Sci. USA 88, 7298-7302.[Abstract/Free Full Text]

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				H. Colognato, J. Galvin, Z. Wang, J. Relucio, T. Nguyen, D. Harrison, P. D. Yurchenco, and C. ffrench-Constant Identification of dystroglycan as a second laminin receptor in oligodendrocytes, with a role in myelination Development, May 1, 2007; 134(9): 1723 - 1736. [Abstract] [Full Text] [PDF]

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				T. Kuhlmann, L. Remington, I. Cognet, L. Bourbonniere, S. Zehntner, F. Guilhot, A. Herman, A. Guay-Giroux, J. P. Antel, T. Owens, et al. Continued Administration of Ciliary Neurotrophic Factor Protects Mice from Inflammatory Pathology in Experimental Autoimmune Encephalomyelitis Am. J. Pathol., August 1, 2006; 169(2): 584 - 598. [Abstract] [Full Text] [PDF]

				B. Emery, H. S. Cate, M. Marriott, T. Merson, M. D. Binder, C. Snell, P. Y. Soo, S. Murray, B. Croker, J.-G. Zhang, et al. Suppressor of cytokine signaling 3 limits protection of leukemia inhibitory factor receptor signaling against central demyelination PNAS, May 16, 2006; 103(20): 7859 - 7864. [Abstract] [Full Text] [PDF]

				R P Lisak, J A Benjamins, B Bealmear, B Yao, S Land, L Nedelkoska, and D Skundric Differential effects of Th1, monocyte/macrophage and Th2 cytokine mixtures on early gene expression for immune-related molecules by central nervous system mixed glial cell cultures Multiple Sclerosis, April 1, 2006; 12(2): 149 - 168. [Abstract] [PDF]

				M. I. Givogri, F. Galbiati, S. Fasano, S. Amadio, L. Perani, D. Superchi, P. Morana, U. Del Carro, S. Marchesini, R. Brambilla, et al. Oligodendroglial progenitor cell therapy limits central neurological deficits in mice with metachromatic leukodystrophy. J. Neurosci., March 22, 2006; 26(12): 3109 - 3119. [Abstract] [Full Text] [PDF]

				P. H. Larsen, A. G. DaSilva, K. Conant, and V. W. Yong Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice. J. Neurosci., February 22, 2006; 26(8): 2207 - 2214. [Abstract] [Full Text] [PDF]

				C. Girard, A.-P. Bemelmans, N. Dufour, J. Mallet, C. Bachelin, B. Nait-Oumesmar, A. Baron-Van Evercooren, and F. Lachapelle Grafts of Brain-Derived Neurotrophic Factor and Neurotrophin 3-Transduced Primate Schwann Cells Lead to Functional Recovery of the Demyelinated Mouse Spinal Cord J. Neurosci., August 31, 2005; 25(35): 7924 - 7933. [Abstract] [Full Text] [PDF]

				R. D. McKinnon, S. Waldron, and M. E. Kiel PDGF {alpha}-Receptor Signal Strength Controls an RTK Rheostat That Integrates Phosphoinositol 3'-Kinase and Phospholipase C{gamma} Pathways during Oligodendrocyte Maturation J. Neurosci., April 6, 2005; 25(14): 3499 - 3508. [Abstract] [Full Text] [PDF]

				Q.-L. Cui, W.-H. Zheng, R. Quirion, and G. Almazan Inhibition of Src-like Kinases Reveals Akt-dependent and -independent Pathways in Insulin-like Growth Factor I-mediated Oligodendrocyte Progenitor Survival J. Biol. Chem., March 11, 2005; 280(10): 8918 - 8928. [Abstract] [Full Text] [PDF]

				M. Xin, T. Yue, Z. Ma, F.-f. Wu, A. Gow, and Q. R. Lu Myelinogenesis and Axonal Recognition by Oligodendrocytes in Brain Are Uncoupled in Olig1-Null Mice J. Neurosci., February 9, 2005; 25(6): 1354 - 1365. [Abstract] [Full Text] [PDF]

				C. M. Schoonover, M. M. Seibel, D. M. Jolson, M. J. Stack, R. J. Rahman, S. A. Jones, C. N. Mariash, and G. W. Anderson Thyroid Hormone Regulates Oligodendrocyte Accumulation in Developing Rat Brain White Matter Tracts Endocrinology, November 1, 2004; 145(11): 5013 - 5020. [Abstract] [Full Text] [PDF]

				H. Colognato, S. Ramachandrappa, I. M. Olsen, and C. ffrench-Constant Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development J. Cell Biol., October 25, 2004; 167(2): 365 - 375. [Abstract] [Full Text] [PDF]

				J. Hsieh, J. B. Aimone, B. K. Kaspar, T. Kuwabara, K. Nakashima, and F. H. Gage IGF-I instructs multipotent adult neural progenitor cells to become oligodendrocytes J. Cell Biol., January 5, 2004; 164(1): 111 - 122. [Abstract] [Full Text] [PDF]

				H. Dong, A. Fazzaro, C. Xiang, S. J. Korsmeyer, M. F. Jacquin, and J. W. McDonald Enhanced Oligodendrocyte Survival after Spinal Cord Injury in Bax-Deficient Mice and Mice with Delayed Wallerian Degeneration J. Neurosci., September 24, 2003; 23(25): 8682 - 8691. [Abstract] [Full Text] [PDF]

				J. L. Mason, S. Xuan, I. Dragatsis, A. Efstratiadis, and J. E. Goldman Insulin-Like Growth Factor (IGF) Signaling through Type 1 IGF Receptor Plays an Important Role in Remyelination J. Neurosci., August 20, 2003; 23(20): 7710 - 7718. [Abstract] [Full Text] [PDF]

				J. Imitola, E. Y. Snyder, and S. J. Khoury Genetic programs and responses of neural stem/progenitor cells during demyelination: potential insights into repair mechanisms in multiple sclerosis Physiol Genomics, August 15, 2003; 14(3): 171 - 197. [Abstract] [Full Text] [PDF]

				J. Y. Kim, Q. Sun, M. Oglesbee, and S. O. Yoon The Role of ErbB2 Signaling in the Onset of Terminal Differentiation of Oligodendrocytes In Vivo J. Neurosci., July 2, 2003; 23(13): 5561 - 5571. [Abstract] [Full Text] [PDF]

				L. Y. S. Oh, A. Denninger, J. S. Colvin, A. Vyas, S. Tole, D. M. Ornitz, and R. Bansal Fibroblast Growth Factor Receptor 3 Signaling Regulates the Onset of Oligodendrocyte Terminal Differentiation J. Neurosci., February 1, 2003; 23(3): 883 - 894. [Abstract] [Full Text] [PDF]

				J. A. Botella, D. Kretzschmar, C. Kiermayer, P. Feldmann, D. A. Hughes, and S. Schneuwly Deregulation of the Egfr/Ras Signaling Pathway Induces Age-related Brain Degeneration in the Drosophila Mutant vap Mol. Biol. Cell, January 1, 2003; 14(1): 241 - 250. [Abstract] [Full Text]

				E. Chaum and H. Yang Transgenic Expression of IGF-1 Modifies the Proliferative Potential of Human Retinal Pigment Epithelial Cells Invest. Ophthalmol. Vis. Sci., December 1, 2002; 43(12): 3758 - 3764. [Abstract] [Full Text] [PDF]

				E. Molina-Holgado, J. M. Vela, A. Arevalo-Martin, G. Almazan, F. Molina-Holgado, J. Borrell, and C. Guaza Cannabinoids Promote Oligodendrocyte Progenitor Survival: Involvement of Cannabinoid Receptors and Phosphatidylinositol-3 Kinase/Akt Signaling J. Neurosci., November 15, 2002; 22(22): 9742 - 9753. [Abstract] [Full Text] [PDF]

				B. Stankoff, M.-S. Aigrot, F. Noel, A. Wattilliaux, B. Zalc, and C. Lubetzki Ciliary Neurotrophic Factor (CNTF) Enhances Myelin Formation: A Novel Role for CNTF and CNTF-Related Molecules J. Neurosci., November 1, 2002; 22(21): 9221 - 9227. [Abstract] [Full Text] [PDF]

				P. Ye, L. Li, R. G. Richards, R. P. DiAugustine, and A. J. D'Ercole Myelination Is Altered in Insulin-Like Growth Factor-I Null Mutant Mice J. Neurosci., July 15, 2002; 22(14): 6041 - 6051. [Abstract] [Full Text] [PDF]

				S. Lehnardt, C. Lachance, S. Patrizi, S. Lefebvre, P. L. Follett, F. E. Jensen, P. A. Rosenberg, J. J. Volpe, and T. Vartanian The Toll-Like Receptor TLR4 Is Necessary for Lipopolysaccharide-Induced Oligodendrocyte Injury in the CNS J. Neurosci., April 1, 2002; 22(7): 2478 - 2486. [Abstract] [Full Text] [PDF]

				R. Giess, M. Maurer, R. Linker, R. Gold, M. Warmuth-Metz, K. V. Toyka, M. Sendtner, and P. Rieckmann Association of a Null Mutation in the CNTF Gene With Early Onset of Multiple Sclerosis Arch Neurol, March 1, 2002; 59(3): 407 - 409. [Abstract] [Full Text] [PDF]