Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity

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Akam, M (1987). The molecular basis for metameric pattern in the Drosophila embryo. Development 101, 1-22.[Abstract]

Andrew, D. J. and Scott, M. P (1992). Downstream of the homeotic genes. New Biologist 4, 5-15.[Medline]

Balling, R., Mutter, G., Gruss, P. and Kessel,M (1989). Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice. Cell 58, 337-347.[Medline]

Bergson, C. and McGinnis,W (1990). An autoregulatory enhancer element of the Drosophila homeotic gene Deformed. EMBO J 9, 4287-4297.[Medline]

Bermingham, J. R. J. and Scott,M. P (1988). Developmentally regulated alternative splicing of transcripts from the Drosophila homeotic gene Antennapedia can produce four different proteins. EMBO J 7, 3211-3222.[Medline]

Carroll, S. B., Laymon, R. A., McCutcheon, M. A., Riley, P. D. and Scott,M. P (1986). The localization and regulation of Antennapedia protein expression in Drosophila embryos. Cell 47, 113-122.[Medline]

Casas-Finet, J. R., Fischer, K. R. and Karpel,R. L (1992). Structural basis for the nucleic acid binding cooperativity of bacteriophage T4 gene 32 protein: The Lys/Arg)3 (Ser/Thr)2 (LAST) motif. Proc. Nat. Acad. Sci. U.S.A 89, 1050-1054.[Abstract/Free Full Text]

Cribbs, D. L., Pultz, M. A., Johnson, D., Mazzulla, M. and Kaufman,T. C (1992). Structural complexity and evolutionary conservation of the Drosophila homeotic gene proboscipedia. EMBO J 11, 1437-1449.[Medline]

Denell, R. E., Hummels, K. R., Wakimoto, B. T. and Kaufman,T. C (1981). Developmental studies of lethality associated with the Antennapedia gene complex in Drosophila melanogaster. Dev. Biol 81, 43-50.[Medline]

Duncan, I. M (1987). The bithorax complex. Ann. Rev. Genet 21, 285-319.[Medline]

Fasano, L., R\232der, L., Core, N., Alexandre, E., Vola, C., Jacq, B. and Kerridge,S (1991). The gene teashirt is required for the development of Drosophila embryonic trunk segments and encodes a protein with widely spaced zinc fingers. Cell 64, 63-79.[Medline]

Frischer, L. E., Hagen, F. S. and Garber, R. L (1986). An inversion that disrupts the Antennapedia gene causes abnormal structure and localization of RNAs. Cell 47, 1017-1023.[Medline]

Gibson, G. and Gehring,W. J (1988). Head and thoracic transformations caused by ectopic expression of Antennapedia during Drosophila development. Development 102, 657-675.[Abstract/Free Full Text]

Gibson, G., Schier, A., LeMotte, P. and Gehring,W. J (1990). The specificities of Sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain. Cell 62, 1087-1103.[Medline]

Glicksman, M. A. and Brower,D. L (1988). Expression of the Sex combs reduced protein in Drosophila larvae. Dev. Biol 127, 113-8.[Medline]

Gonzalez-Reyes, A. and Morata,G. ( (1990). The developmental effect of overexpressing a Ubx protein in Drosophila embryo is dependent on its interaction with other homeotic products. Cell 61, 515-522.[Medline]

Gonzalez-Reyes, A., Urquia, N., Gehring, W. J., Struhl, G. and Morata, G (1990). Are cross-regulatory interactions between homoeotic genes functionally significant?. Nature 344, 78-80.[Medline]

Goutte, C. and Johnson,A. D (1988). a1 protein alters the DNA binding specificity of a2 repressor. Cell 52, 875-882.[Medline]

Hanes, S. D. and Brent,R (1989). DNA specificity of the bicoid activator protein is determined by homeodomain recognition helix residue 9. Cell 57, 1275-1283.[Medline]

Hazelrigg, T. and Kaufman,T. C (1983). Revertants of dominant mutations associated with the Antennapedia gene complex of Drosophila melanogaster. Genetics 105, 581-600.[Abstract/Free Full Text]

Heuer, J. G. and Kaufman,T. C (1992). Homeotic genes have specific functional roles in the establishment of the Drosophila embryonic peripheral nervous system. Development 115, 35-47.[Abstract]

Immergluck, K., Lawrence, P. A. and Bienz,M (1990). Induction across germ layers in Drosophila mediated by a genetic cascade. Cell 62, 261-268.[Medline]

Johnson, W. A. and Hirsh, J (1990). Binding of a Drosophila POU-domain protein to a sequence element regulating gene expression in specific dopaminergic neurons. Nature 343, 467-70.[Medline]

Kaufman, T. C., Lewis, R. and Wakimoto,B (1980). Cytogenetic analysis of chromosome 3 in Drosophila melanogaster : the homeotic gene complex in polytene chromosomal interval 84A, B. Genetics 94, 115-133.[Abstract/Free Full Text]

Kaufman, T. C., Seeger, M. A. and Olsen,G (1990). Molecular and genetic organization of the Antennapedia gene complex of Drosophila melanogaster. Adv. Genet 27, 309-362.[Medline]

Keleher, C. A., Goutte, C. and Johnson,A. D (1988). The yeast cell-type specific repressor2 acts cooperatively with a non-cell-type specific protein. Cell 53, 927-936.[Medline]

Kissinger, C. R., Liu, B., Martin, B. E., Kornberg, T. B. and Pabo,C. O (1990). Crystal structure of an engrailed homeodomain-DNA complex at 2.8 \201 resolution: A framework for understanding homeodomain-DNA interactions. Cell 63, 579-590.[Medline]

Koerner, T. J., Hill, J. E., Myers, A. M. and Tzagoloff,A (1991). High-expression vectors with multiple cloning sites for construction of trpE fusion genes: pATH vectors. Methods Enzymol 194, 477-490.[Medline]

Kornfeld, K., Saint, R. B., Beachy, P. A., Harte, P. J., Peattie, D. A. and Hogness,D. S (1989). Structure and expression of a family of Ultrabithorax mRNAs generated by alternative splicing and polyadenylation in Drosophila. Genes Dev 3, 243-258.[Abstract/Free Full Text]

Kristie, T. M., LeBowitz, J. H. and Sharp,P. A (1989). The octamer-binding proteins form multi-protein-DNA complexes with the HSV alpha TIF regulatory protein. EMBOJ 8, 4229-38.[Medline]

Kuroiwa, A., Kloter, U., Baumgartner, P. and Gehring,W. J (1985). Cloning of the homeotic Sex combs reduced gene on Drosophila and in situ localization of its transcripts. EMBO J 4, 3757-3764.[Medline]

Kuziora, M. A. and McGinnis, W (1988). Autoregulation of a Drosophila homeotic selector gene. Cell 55, 477-485.[Medline]

Lai, J.-S., Cleary, M. A. and Herr,W (1992). A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain. Genes Dev 6, 2058-2065.[Abstract/Free Full Text]

Laughon, A., Boulet, A. M., Bermingham, J. R. J., Laymon, R. A. and Scott,M. P (1986). Structure of transcripts from the homeotic Antennapedia gene of Drosophila melanogaste r: two promoters control the major protein-coding region. Mol. Cell. Biol 6, 4676-4689.[Abstract/Free Full Text]

LeBowitz, J. H., Clerc, R. G., Brenowitz, M. and Sharp,P. A (1989). The Oct-2 protein binds cooperatively to adjacent octamer sites. Genes Dev 3, 1625-38.[Abstract/Free Full Text]

Lewis, E. B (1963). Genes and developmental pathways. Am. Zool 3, 33-56.

Lin, L. and McGinnis,W (1992). Mapping functional specificity in the Dfd and Ubx homeo domains. Genes Dev 6, 1071-1081.[Abstract/Free Full Text]

Lufkin, T., Mark, M., Hart, C. P., Dolle, P, LeMeur, M. and Chambon, P (1992). Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene. Nature 359, 835-841.[Medline]

Mahaffey, J. W. and Kaufman,T. C (1987). Distribution of the Sex combs reduced gene products in Drosophila melanogaster. Genetics 117, 51-60.[Abstract/Free Full Text]

Mann, R. S. and Hogness, D. S (1990). Functional dissection of Ultrabithorax proteins in D. melanogaster. Cell 60, 597-610.[Medline]

Martinez-Arias, A (1986). The Antennapedia gene is required and expressed in parasegments 4 and 5 of the Drosophila embryo. EMBO J 5, 135-141.[Medline]

Mendel, D. B. and Crabtree,G. R (1991). HNF-1, a member of a novel class of dimerizing homeodomain proteins. J. Biol. Chem 266, 677-680.[Free Full Text]

Mendel, D. B., Khavari, P. A., Conley, P. B., Graves, M. K., Hansen, L. P., Admon, A. and Crabtree,G. R (1991). Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein. Science 254, 1762-1767.[Abstract/Free Full Text]

Noordermeer, J., Johnston, P., Rijsewijk, F., Nusse, R. and Lawrence, P. A (1992). The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo. Development 116, 711-719.[Abstract]

O'Connor, M. B., Binari, R., Perkins, L. A. and Bender,W (1988). Alternative RNA products from the Ultrabithorax domain of the bithorax complex. EMBO J 7, 435-45.[Medline]

Otting, G., Qian, Y. Q., Billeter, M., Muller, M., Affolter, M., Gehring, W. J. and Wuthrich,K (1990). Protein-DNA contacts in the structure of a homeodomain-DNA complex determined by nuclear magnetic resonance spectroscopy in solution. EMBO J 9, 3085-3092.[Medline]

Pabo, C. O. and Sauer,R. T (1984). Protein-DNA recognition. Ann. Rev. Biochem 53, 293-321.[Medline]

Pabo, C. O. and Sauer,R. T (1992). Transcription factors: Structural families and principles of DNA recognition. Ann. Rev. Biochem 61, 1053-1095.[Medline]

Panzer, S., Weigel, D. and Beckendorf,S. K (1992). Organogenesis in Drosophila melanogaster: Embryonic salivary gland determination is controlled by homeotic and dorsoventral patterning genes. Development 114, 49-57.[Abstract]

Pattatucci, A. M. and Kaufman,T. C (1991). The homeotic gene Sex combs reduced of Drosophila melanogaster is differentially regulated in the embryonic and imaginal stages of development. Genetics 129, 443-461.[Abstract]

Peifer, M. and Wieschaus,E (1990). Mutations in the Drosophila gene extradenticle affect the way specific homeo domain proteins regulate segmental identity. Genes Dev 4, 1209-1223.[Abstract/Free Full Text]

Percival-Smith, A., Muller, M., Affolter, M. and Gehring,W. J (1990). The interaction with DNA of wild-type and mutant fushi tarazu homeodomains. EMBO J 9, 3967-3974.[Medline]

Pomerantz, J. L., Kristie, T. M. and Sharp,P. A (1992). Recognition of the surface of a homeo domain protein. Genes Dev 6, 2047-2057.[Abstract/Free Full Text]

Regulski, M., Dessain, S., McGinnis, N., and McGinnis,W (1991). High-affinity binding sites for the Deformed protein are required for the function of an autoregulatory enhancer of the Deformed gene. Genes Dev 5, 278-286.[Abstract/Free Full Text]

Reuter, R., Panganiban, G. E. F., Hoffmann, F. M. and Scott,M. P (1990). Homeotic genes regulate the spatial expression of putative growth factors in the visceral mesoderm of Drosophila embryos. Development 110, 1031-1040.[Abstract/Free Full Text]

Reuter, R. and Scott,M. P (1990). Expression and functions of the homoeotic genes Antennapedia and Sex combs reduced in the embryonic midgut of Drosophila. Development 109, 289-303.[Abstract]

Riley, P. D., Carroll, S. B. and Scott,M. P (1987). The expression and regulation of Sex combs reduced protein in Drosophila embryos. Genes Dev 1, 716-730.[Abstract/Free Full Text]

R\232der, L., Vola, C. and Kerridge,S (1992). The role of the teashirt gene in trunk segmental identity in Drosophila. Development 115, 1017-1033.[Abstract]

Rubin, G. M. and Spradling,A. C (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-53.[Abstract/Free Full Text]

Sanchez-Herrero, E., Vernos, I., Marco, R. and Morata,G (1985). Genetic organization of Drosophila bithorax complex. Nature 313, 108-13.[Medline]

Sanger, F., Nicklen, S. and Coulson,A. R (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci.USA 74, 5463-5467.[Abstract/Free Full Text]

Sato, T., Hayes, P. H. and Denell,R. E (1985). Homeosis in Drosophila: Roles and spatial patterns of expression of the Antennapedia and Sex Combs Reduced loci in embryogenesis. Dev. Biol 111, 171-192.

Schneuwly, S. and Gehring,W. J (1985). Homeotic transformation of thorax into head: Developmental analysis of a new Antennapedia allele in Drosophila melanogaster. Dev. Biol 108, 377-386.

Schneuwly, S., Klemenz, R. and Gehring,W. J (1987). Redesigning the body plan of Drosophila by ectopic expression of the homoeotic gene Antennapedia. Nature 325, 816-818.[Medline]

Schneuwly, S., Kuroiwa, A. and Gehring,W. J (1987). Molecular analysis of the dominant homeotic Antennapedia phenotype. EMBO J 6, 201-206.[Medline]

Scott, M. P., Weiner, A. J., Hazelrigg, T. I., Polisky, B. A., Pirrotta, V., Scalenghe, F. and Kaufman,T. C (1983). The molecular organization of the Antennapedia locus of Drosophila. Cell 35, 763-776.[Medline]

Smith, D. L. and Johnson,A. D (1992). A molecular mechanism for combinatorial control in yeast: MCM1 protein sets the spacing and orientation of the homeodomains of an a2 dimer. Cell 68, 133-142.[Medline]

Spradling, A. C. and Rubin,G. M (1982). Transposition of cloned P elements into Drosophila germ line chromosomes. Science 218, 341-7.[Abstract/Free Full Text]

Steitz, T. A (1990). Structural studies of protein-nucleic acid interaction: the sources of sequence-specific binding. Quart. Rev. Biophysics 23, 205-280.[Medline]

Stern, S. and Herr,W (1991). The herpes simplex virus trans-activator VP16 recognizes the Oct-1 homeo domain: Evidence for a homeo domain recognition subdomain. Genes Dev 5, 2555-2566.[Abstract/Free Full Text]

Stern, S., Tanaka, M. and Herr,W (1989). The Oct-1 homeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16. Nature 341, 624-630.[Medline]

Stroeher, V. L., Gaiser, J. C. and Garber,R. L (1988). Alternative RNA splicing that is spatially regulated: generation of transcripts from the Antennapedia gene of Drosophila melanogaster with different protein-coding regions. Mol. Cell. Biol 8, 4143-4154.[Abstract/Free Full Text]

Struhl, G (1982). Genes controlling segmental specification in the Drosophila thorax. Proc. Natl. Acad. Sci. USA 79, 7380-4.[Abstract/Free Full Text]

Tokunaga, C. and Stern,C (1965). The developmental autonomy of extra sex combs in Drosophila melanogaster. Dev. Biol 11, 50-81.[Medline]

Treacy, M. N., He, X. and Rosenfeld,M. G (1991). I-POU: A POU-domain protein that inhibits neuron-specific gene activation. Nature 350, 577-584.[Medline]

Treacy, M. N., Neilson, L. I., Turner, E. E., He, X. and Rosenfeld,M. G (1992). Twin of I-POU: a two amino acid difference in the I-POU homeodomain distinguishes an activator from an inhibitor of transcription. Cell 68, 491-505.[Medline]

Treisman, J., G\232nczy, P., Vashishtha, M., Harris, E. and Desplan,C (1989). A single amino acid can determine the DNA-binding specificity of homeodomain proteins. Cell 59, 553-562.[Medline]

Tremml, G. and Bienz,M (1989). Homeotic gene expression in the visceral mesoderm of Drosophila embryos. EMBO J 8, 2677-2685.[Medline]

Vachon, G., Cohen, B., Pfeifle, C., McGuffin, M. E., Botas, J. and Cohen,S. M (1992). Homeotic genes of the bithorax complex repress limb development in the abdomen of the Drosophila embryo through the target gene Distal-less. Cell 71, 437-450.[Medline]

van der Meer, J. M (1977). Optical clean and permanent whole mount preparation for phase constrast microscopy of cuticulat structures in insect larvae. Dros. Inf. Serv 52, 160-.

Wakimoto, B. T. and Kaufman,T. C (1981). Analysis of larval segmentation in lethal genotypes associated with the Antennapedia gene complex in Drosophila melanogaster. Dev. Biol 81, 51-64.[Medline]

Wakimoto, B. T., Turner, F. R. and Kaufman,T. C (1984). Defects in embryogenesis in mutants associated with the Antennapedia gene complex of Drosophila melanogaster. Dev. Biol 102, 147-172.[Medline]

Weigel, D. and J\212ckle,H (1990). The fork head domain: A novel DNA binding motif of eukaryotic transcription factors?. Cell 63, 455-456.[Medline]

Weigel, D., Jurgens, G., Kuttner, F., Seifert, E. and J\212ckle,H (1989). The homeotic gene fork head encodes a nuclear protein and is expressed in the terminal regions of the Drosophila embryo. Cell 57, 645-658.[Medline]

Wolberger, C., Vershon, A. K., Liu, B., Johnson, A. D. and Pabo,C. O (1991). Crystal structure of a MAT2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions. Cell 67, 517-528.[Medline]

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				C. D. McCabe and J. W. Innis A genomic approach to the identification and characterization of HOXA13 functional binding elements Nucleic Acids Res., November 30, 2005; 33(21): 6782 - 6794. [Abstract] [Full Text] [PDF]

				B. S. Emerald, J. Curtiss, M. Mlodzik, and S. M. Cohen distal antenna and distal antenna related encode nuclear proteins containing pipsqueak motifs involved in antenna development in Drosophila Development, March 15, 2003; 130(6): 1171 - 1180. [Abstract] [Full Text] [PDF]

				A. Gutierrez, L. Knoch, H. Witte, and R. J. Sommer Functional specificity of the nematode Hox gene mab-5 Development, March 1, 2003; 130(5): 983 - 993. [Abstract] [Full Text] [PDF]

				A. Abzhanov, S. Holtzman, and T. C. Kaufman The Drosophila proboscis is specified by two Hox genes, proboscipedia and Sex combs reduced, via repression of leg and antennal appendage genes Development, July 15, 2001; 128(14): 2803 - 2814. [Abstract] [Full Text] [PDF]

				A. E. Uv, P. Roth, N. Xylourgidis, A. Wickberg, R. Cantera, and C. Samakovlis members only encodes a Drosophila nucleoporin required for Rel protein import and immune response activation Genes & Dev., August 1, 2000; 14(15): 1945 - 1957. [Abstract] [Full Text]

				J. K. Grenier and S. B. Carroll Functional evolution of the Ultrabithorax protein PNAS, January 18, 2000; 97(2): 704 - 709. [Abstract] [Full Text] [PDF]

				H. D. Ryoo and R. S. Mann The control of trunk Hox specificity and activity by Extradenticle Genes & Dev., July 1, 1999; 13(13): 1704 - 1716. [Abstract] [Full Text]

				X. Li and W. McGinnis Activity regulation of Hox proteins, a mechanism for altering functional specificity in development and evolution PNAS, June 8, 1999; 96(12): 6802 - 6807. [Abstract] [Full Text] [PDF]

				P. Seshaiah and D. J. Andrew WRS-85D: A Tryptophanyl-tRNA Synthetase Expressed to High Levels in the Developing Drosophila Salivary Gland Mol. Biol. Cell, May 1, 1999; 10(5): 1595 - 1608. [Abstract] [Full Text]

				T. Kophengnavong, A. S. Carroll, and T. K. Blackwell The SKN-1 Amino-Terminal Arm Is a DNA Specificity Segment Mol. Cell. Biol., April 1, 1999; 19(4): 3039 - 3050. [Abstract] [Full Text] [PDF]

				S Goto and S Hayashi Proximal to distal cell communication in the Drosophila leg provides a basis for an intercalary mechanism of limb patterning Development, January 8, 1999; 126(15): 3407 - 3413. [Abstract] [PDF]

				A Abzhanov and T. Kaufman Novel regulation of the homeotic gene Scr associated with a crustacean leg-to-maxilliped appendage transformation Development, January 3, 1999; 126(6): 1121 - 1128. [Abstract] [PDF]

				M. A. Viganò, G. Di Rocco, V. Zappavigna, and F. Mavilio Definition of the Transcriptional Activation Domains of Three Human HOX Proteins Depends on the DNA-Binding Context Mol. Cell. Biol., November 1, 1998; 18(11): 6201 - 6212. [Abstract] [Full Text]

				C. Zeng, N. J. Justice, S. Abdelilah, Y.-M. Chan, L. Y. Jan, and Y. N. Jan The Drosophila LIM-only gene, dLMO, is mutated in Beadex alleles and might represent an evolutionarily conserved function in appendage development PNAS, September 1, 1998; 95(18): 10637 - 10642. [Abstract] [Full Text] [PDF]

				E. N. Tolkunova, M. Fujioka, M. Kobayashi, D. Deka, and J. B. Jaynes Two Distinct Types of Repression Domain in Engrailed: One Interacts with the Groucho Corepressor and Is Preferentially Active on Integrated Target Genes Mol. Cell. Biol., May 1, 1998; 18(5): 2804 - 2814. [Abstract] [Full Text]

				S. Weiler, J. M. Gruschus, D. H.�H. Tsao, L. Yu, L.-H. Wang, M. Nirenberg, and J. A. Ferretti Site-directed Mutations in the vnd/NK-2 Homeodomain. BASIS OF VARIATIONS IN STRUCTURE AND SEQUENCE-SPECIFIC DNA BINDING J. Biol. Chem., May 1, 1998; 273(18): 10994 - 11000. [Abstract] [Full Text] [PDF]

				L Jaffe, H D Ryoo, and R S Mann A role for phosphorylation by casein kinase II in modulating Antennapedia activity in Drosophila. Genes & Dev., May 15, 1997; 11(10): 1327 - 1340. [Abstract] [PDF]

				M. L. Phelan and M. S. Featherstone Distinct HOX N-terminal Arm Residues Are Responsible for Specificity of DNA Recognition by HOX Monomers and HOX�PBX Heterodimers J. Biol. Chem., March 28, 1997; 272(13): 8635 - 8643. [Abstract] [Full Text] [PDF]

				A Percival-Smith, J Weber, E Gilfoyle, and P Wilson Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster Development, January 12, 1997; 124(24): 5049 - 5062. [Abstract] [PDF]

				S. Chan, H. Ryoo, A Gould, R Krumlauf, and R. Mann Switching the in vivo specificity of a minimal Hox-responsive element Development, January 5, 1997; 124(10): 2007 - 2014. [Abstract] [PDF]

				P.C. Denny, W.D. Ball, and R.S. Redman Salivary Glands: A Paradigm for Diversity of Gland Development Critical Reviews in Oral Biology & Medicine, January 1, 1997; 8(1): 51 - 75. [Abstract] [Full Text] [PDF]

				A Zhu and M. Kuziora Functional domains in the Deformed protein Development, January 5, 1996; 122(5): 1577 - 1587. [Abstract] [PDF]

				J. Endrizzi, J. Cronk, W Wang, G. Crabtree, and T Alber Crystal structure of DCoH, a bifunctional, protein-binding transcriptional coactivator Science, April 28, 1995; 268(5210): 556 - 559. [Abstract] [PDF]

				A McCormick, N Core, S Kerridge, and M. Scott Homeotic response elements are tightly linked to tissue-specific elements in a transcriptional enhancer of the teashirt gene Development, January 9, 1995; 121(9): 2799 - 2812. [Abstract] [PDF]

				J Castelli-Gair and M Akam How the Hox gene Ultrabithorax specifies two different segments: the significance of spatial and temporal regulation within metameres Development, January 9, 1995; 121(9): 2973 - 2982. [Abstract] [PDF]

				J. Manak, L. Mathies, and M. Scott Regulation of a decapentaplegic midgut enhancer by homeotic proteins Development, January 12, 1994; 120(12): 3605 - 3619. [Abstract] [PDF]

				L. Mathies, S Kerridge, and M. Scott Role of the teashirt gene in Drosophila midgut morphogenesis: secreted proteins mediate the action of homeotic genes Development, January 10, 1994; 120(10): 2799 - 2809. [Abstract] [PDF]

				R Dawes, I Dawson, F Falciani, G Tear, and M Akam Dax, a locust Hox gene related to fushi-tarazu but showing no pair-rule expression Development, January 6, 1994; 120(6): 1561 - 1572. [Abstract] [PDF]

				A Mak and A D Johnson The carboxy-terminal tail of the homeo domain protein alpha 2 is required for function with a second homeo domain protein. Genes & Dev., October 1, 1993; 7(10): 1862 - 1870. [Abstract] [PDF]

				S. Chauvet, S. Merabet, D. Bilder, M. P. Scott, J. Pradel, and Y. Graba Distinct Hox protein sequences determine specificity in different tissues PNAS, April 11, 2000; 97(8): 4064 - 4069. [Abstract] [Full Text] [PDF]