A novel role for thyroid hormone, glucocorticoids and retinoic acid in timing oligodendrocyte development

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Abney, E. R., Bartlett, P. F. and Raff,M. C (1981). Astrocytes, ependymal cells and oligodendrocytes develop on schedule in dissociated cultures of embryonic rat brain. Dev. Biol 83, 301-310.[Medline]

Allen, T. D. and Dexter, T. M (1982). Ultrastructural aspects of erythropoietic differentiation in long term bone marrow culture. Differentiation 21, 86-94.[Medline]

Almazan, G., Honegger, P. and Matthieu, J. M (1985). Triiodothyronine stimulation of oligodendrocyte differentiation and myelination. Dev. Neurosci 7, 45-54.[Medline]

Almazan, G., Honegger, P., Du Pasquier, P. and Mathheiu, J. M (1986). Dexamethasone stimulates the biochemical differentiation of fetal forebrain cells in reaggregating cultures. Dev. Neurosci 8, 14-23.[Medline]

Angel, P. and Karin, M (1991). The role of jun, fos and the AP-1 complex in cell proliferation and transformation. Biochim. Biophys. Acta 1072, 129-157.[Medline]

Barres, B. A., Hart, I. K., Coles, H. S. R. Burne, J. F., Voyvodic, J. T., Richardson, W. D. and Raff, M. C (1992). Cell death and control of cell survival in the oligodendrocyte lineage. Cell 70, 31-46.[Medline]

Barres, B. A., Jacobson, M. D., Schmid, R., Sendtner, M. and Raff, M. C (1993). Does oligodendrocyte survival depend on axons?. Curr. Biol 3, 489-497.

Barres, B. A., Schmid, R., Sendtner, M. and Raff, M. C (1993). MultipleB. A. Barres, M. A. Lazarand M. C. Raff1107Hydrophobic signals time oligodendrocyte developmentextracellular signals are required for long-term oligodendrocyte survival. Development 118, 283-295.[Abstract]

Bohn, M. C. and Friedrich, V. L (1982). Recovery of myelination in rat optic nerve after developmental retardation by cortisol. J. Neurosci 2, 1292-1298.[Abstract]

Bohn, M. C., Howard, E., Vielkind, U. and Krozowski, Z (1991). Glial cells express both mineralocorticoid and glucocorticoid receptors. J. Steroid Biochem. Molec. Biol 40, 105-111.[Medline]

Bradley, D. J., Towle, H. C. and Young, W. S. III (1992). Spatial and temporal expression of alpha and beta thyroid hormone receptor mRNAs, including the2 subtype, in the developing mammalian CNS. J. Neurosci 12, 2288-2302.[Abstract]

Brent, G. A., Moore, D. D. and Larsen, P. R (1991). Thyroid hormone regulation of gene expression. Annu. Rev. Physiol 53, 17-35.[Medline]

Campisi, J. and Seshadri, T (1990). Repression of c-fos transcription and an altered genetic program in senescent human fibroblasts. Science 247, 205-209.[Abstract/Free Full Text]

Cristofalo, V. J. and Pignolo, R (1993). Replicative senescence of human fibroblast-like cells in culture. Physiol. Rev 73, 617-638.[Abstract/Free Full Text]

Dainak, N., Hoffmann, R., Maffei, L. A. and Forget, B. G (1978). Potentiation of human erythropoiesis in vitro by thyroid hormone. Nature 272, 260-262.[Medline]

Dawson, G. and Kernes, S. M (1979). Mechanism of action of hydrocortisone potentiation of sulfogalactosylceramide synthesis in mouse oligodendroglioma clonal cell lines. J. Biol.Chem 254, 163-167.[Free Full Text]

DeLuca, L. M (1991). Retinoids and their receptors in differentiation, embryogenesis, and neoplasia. FASEB J 5, 2924-2933.[Abstract]

Diamond, M. L., Miner, J. N., Yoshinaga, S. K. and Yamamoto, K. R (1990). c-Jun and c-Fos levels specify positive or negative glucocorticoid regulation from a composite GRE. Science 249, 1266-72.[Abstract/Free Full Text]

Dice, J. F (1993). Cellular and molecular mechanisms of aging. Physiol. Rev 73, 149-159.[Free Full Text]

Dussault, J. H. and Ruel, J (1987). Thyroid hormones and brain development. Ann. Rev. Physiol 49, 321-334.[Medline]

Edwards, R. B., Adler, A. J. and Claycomb, R. C (1992). Synthesis of retinoic acid from retinol by cultured rabbit Muller cells. Exp. Eye Res 54, 481-90.[Medline]

Eisenbarth, G. S., Walsh, F. S. and Nirenburg, M (1979). Monoclonal antibodies to a plasma membrane antigen of neurons. Proc. Natl. Acad. Sci. USA 76, 4913-6.[Abstract/Free Full Text]

Forrest, D., Hallbook, F., Persson, H. and Vennstrom, B (1991). Distinct functions for thyroid hormone receptors alpha and beta in brain development indicated by differential expression of receptor genes. EMBO J 10, 269-275.[Medline]

Hackney, J. F., Gross, S. R., Aronow, L. and Pratt, W. B (1970). Specific glucocorticoid-binding macromolecules from mouse fibroblasts growing in vitro. Mol. Pharmacol 6, 500-512.[Abstract/Free Full Text]

Hardy, R. and Reynolds, R (1991). Proliferation and differentiation potential of rat forebrain oligodendrocyte progenitors both in vitro and in vivo. Development 111, 1061-1080.[Abstract/Free Full Text]

Hodin, R. A., Lazar, M. A., Wintman, B. I., Darling, D. S., Koenig, R. J., Larsen, P.R., Moore, D. D. and Chin, W. W (1989). Identification of a thyroid hormone receptor that is pituitary specific. Science 244, 76-79.[Abstract/Free Full Text]

Hodin, R. A., Lazar, M. A. and Chin, W. W (1990). Differential and tissue-specific regulation of multiple c-erbA messenger RNA species by thyroid hormone. J. Clin. Invest 85, 101-105.

Irving, J., Feng, J., Wistrom, C., Pikaart, M. and Villeponteau, B (1992). An altered repertoire of fos/jun (AP-1) at the onset of replicative senescence. Exp. Cell Res 202, 161-166.[Medline]

Johnson, R. S., Lingen, B., Papaioannou, V. E. and Spiegelman, B. M (1993). A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes and Dev 7, 1309-1317.[Abstract/Free Full Text]

Johnson, R. S., Spiegelman, B. M. and Papaioannou, V. E (1992). Pleiotropic effects of a null mutation in the c-fos proto-oncogene. Cell 71, 577-586.[Medline]

Katz, D. and Lazar, M. A (1993). Dominant negative activity of an endogenous thyroid hormone receptor variant (2) is due to competition for binding sites on target genes. J. Biol. Chem 268, 20904-20910.[Abstract/Free Full Text]

Kerppola, T. K.., Luk, D. and Curran, T (1993). Fos is a preferential target of glucocorticoid receptor inhibition of AP-1 activity in vitro. Mol. Cell. Biol 13, 3782-3791.[Abstract/Free Full Text]

Koenig, R. J., Lazar, M. A., Hodin, R. A., Brent, G. A., Larsen, P. R., Chin, W. W. Moore, D. D (1989). Inhibition of thyroid hormone action by a non-hormone binding c-erbA protein generated by alternative mRNA splicing. Nature 337, 659-661.[Medline]

Kumar, S., Cole, R., Chiappelli, F. and deVellis, J (1989). Differential regulation of oligodendrocyte markers by glucocorticoids. Proc. Natl. Acad. Sci. USA 86, 6807-6811.[Abstract/Free Full Text]

Lazar, M. A., Hodin, R. A., Darling, D. S. and Chin, W. W (1988). Identification of a rat c-erbArelated protein which binds deoxyribonucleic acid but does not bind thyroid hormone. Mol. Endocrinol 2, 893-901.[Abstract]

Lazar, M. A (1993). Thyroid hormone receptors: Multiple forms, multiple possibilities. Endocrin. Rev 14, 184-193.[Medline]

Lechan, R. M., Yanping, Q. I., Berrodin, T. J., Davis, K. D., Schwartz, H. L., Strait, K. A., Oppenheimer, J. H.and Lazar M. A (1993). Immunocytochemical delineation of thyroid hormone receptor B2-like immunoreactivity in the rat central nervous system. Endocrin 132, 2461-2469.[Abstract]

Loo, D. T., Fuquay, J. I., Rawson, C. L. and Barnes, D. W (1987). Extended culture of mouse embryo cells without senescence: inhibition by serum. Science 236, 200-202.[Abstract/Free Full Text]

Louis, J. C., Magal, E., Takayama, S. and Varon, S (1993). CNTF protection of oligodendrocytes against natural and tumor necrosis factor induced death. Science 259, 689-692.[Abstract]

Maden, M. and Holder, N (1992). Retinoic acid and development of the central nervous system. BioEssays 14, 431-438.[Medline]

Magaud, J., Sargent, I. and Mason, D. Y (1988). Detection of human white cell proliferative responses by immunoenzymatic measurement of bromodeoxyuridine uptake. J. Immunol. Meth 106, 95-100.[Medline]

Meyer, J. S. and Fairman, K. R (1985). Early adrenalectomy increases myelin content of the rat brain. Dev. Brain Res 17, 1-9.

Miller, R. H., David, S., Patel, R., Abney, E. R. and Raff, M. C (1985). A quantitative immunohistochemical study of macroglial cell development in the rat optic nerve: in vivo evidence for two distinct astrocyte lineages. Dev. Biol 111, 35-41.[Medline]

Mosmann, T (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Meth 65, 55-63.[Medline]

Nicholson, R. C., Mader, S., Nagpal, S., Leid, M., Rochette-Egly, C. and Chambon, P (1990). Negative regulation of the rat stromelysis gene promoter by retinoic acid is mediated by an AP-1 binding site. EMBO J 9, 4443-4454.[Medline]

Noble, M. and Murray, K (1984). Purified astrocytes promote the in vitro divisions of a bipotential glial progenitor cell. EMBO J 3, 2243-2247.[Medline]

Patel, A. J., Lewis, P. D., Balazs, R., Bailey, P. and Lai, M (1979). Effects of thyroxine on postnatal cell acquisition in the rat brain. Brain Res 172, 57-72.[Medline]

Preston, S. L. and McMorris, F. A (1984). Adrenalectomy of rats results in hypomyelination of the central nervous system. J. Neurochem 42, 262-267.[Medline]

Puymirat, J (1992). Thyroid receptors in the rat brain. Prog. Neurobiol 39, 281-294.[Medline]

Quinn, L. S., Holtzer, H. and Nameroff, M (1985). Generaion of chick skeletal muscle cells in groups of 16 from stem cells. Nature 313, 692-694.[Medline]

Raff, M. C., Lillien, L. E., Richardson, W. D., Burne, J. F. and Noble, M. D (1988). Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture. Nature 333, 562-565.[Medline]

Raff, M. C., Miller, R. H. and Noble, M (1983). A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium. Nature 303, 390-396.[Medline]

Ranscht, B., Clapshaw, P. A., Price, J., Noble, M. and Seifert, W (1982). Development of oligodendrocytes and Schwann cells studied with a monoclonal antibody against galactocerebroside. Proc. Natl. Acad. Sci. USA 79, 2709-2713.[Abstract/Free Full Text]

Ransone, L. J. and Verma, I. M (1990). Nuclear proto-oncogenes fos and jun. Annu. Rev. Cell Biol 6, 539-557.

Riabowol, K. J (1992). Transcription factor activity during cellular aging of human diploid fibroblasts. Biochem. Cell Biol 70, 1064-1072.[Medline]

Riabowol, K., Schiff, J. and Gilman, M. Z (1992). Transcription factor AP-1 activity is required for initiation of DNA synthesis and is lost during cellular aging. Proc. Natl. Acad. Sci. USA 89, 157-161.[Abstract/Free Full Text]

Saatcioglu, F., Bartunek, P., Deng, T., Zenke, M. and Karin, M (1993). A conserved C-terminal sequence that is deleted in v-ErbA is esential for the biological activities of c-ErbA. Mol. Cell. Biol 13, 3675-3685.[Abstract/Free Full Text]

Salbert, G., Fanjul, A., Piedrafita, F. J., Lu, X. P., Kim, S. J., Tran, P. and Pfahl, M (1993). Retinoic acid receptors and retinoid X receptor-down-regulate the transforming growth factor- 1 promoter by antagonizing AP-1 activity. Mol. Endocrinol 7, 1347-1356.[Abstract]

Samel, M (1968). Thyroid function during postnatal development in the rat. Gen. Comp. Endocrin 10, 229-234.[Medline]

Schilthuis, J. G., Gann, A. A. and Brockes, J. P (1993). Chimeric retinoic acid/thyroid hormone receptors implicate RAR-1 as mediating growth inhibition by retinoic acid. EMBO J 12, 3459-3466.[Medline]

Schule, R. and Evans, R. M (1991). Retinoic acid is a negative regulator of AP-1 responsive genes. Proc. Natl. Acad. Sci. USA 88, 6092-6096.[Abstract/Free Full Text]

Sikora, E., Kaminska, B., Radziszewska, E. and Kaczmarek, L (1992). Loss of transcription factor AP-1 DNA binding activity during lymphocyte aging in vivo. FEBS Let 312, 179-182.[Medline]

Stephens, J. L. and Pieringer, R. A (1984). Regulation of arylsulphatase A and sulphogalactolipid turnover by cortisol in myelinogenic cultures of cells dissociated from embryonic mouse brain. Biochem. J 219, 689-697.[Medline]

trait, K. A., Schwartz, H. L., Perez-Castillo, A. and Oppenheimer, J. H (1990). Relationship of c-erbA mRNA content to tissue triiodothyronine nuclear binding capacity and function in developing and adult rats. J. Biol. Chem 265, 10514-10521.[Abstract/Free Full Text]

Temple, S. and Raff, M. C (1985). Differentiation of a bipotential glial progenitor cell in single cell microculture. Nature 313, 223-225.[Medline]

Temple, S. and Raff, M. C (1986). Clonal analysis of oligodendrocyte development in culture: evidence for a developmental clock that counts cell divisions. Cell 44, 773-779.[Medline]

Tosic, M., Torch, S., Comte, V., Dolivo, M., Honegger, P. and Matthieu, J. M (1992). Triiodothyronine has diverse and multiple stimulating effects on expression of the major myelin protein genes. J. Neurochem 59, 1770-1777.[Medline]

Walters, S. N. and Morell, P (1981). Effects of altered thyroid states on myelinogenesis. J. Neurochem 36, 1792-1801.[Medline]

Wang, Z. Q., Ovitt, E., Grigoriadis, A. E., Mohle-Steinlein, U., Ruther, U. and Wagner, E. F (1992). Bone and haematopoietic defects in mice lacking c-fos. Nature 360, 741-745.[Medline]

Warringa, R., Hoeben, R., Koper, J., Sykes, J., van Golde, L. and Lopes-Cardozo, M (1987). Hydrocortisone stimulates the development of oligodendrocytes in primary glial cultures and affects glucose metabolism and lipid synthesis in these cultures. Dev. Brain Res 34, 9-86.

Wuarin, L., Sidell, N. and deVellis, J (1991). Retinoids increase perinatal spinal cord neuronal survival and astroglial differentiation. Int. J. Dev. Neurosci 8, 317-326.

Yang-Yen, H. F., Chambard, J. C., Sun, Y. L., Smeal, T., Schmidt, T. J., Drouin, J. and Karin, M (1990). Transcriptional interference between c-jun and the glucocorticoid receptor: mutual inhibition of DNA binding due to direct protein-protein interaction. Cell 62, 1205-1215.[Medline]

Yusta, B., Besnard, F., Ortiz-Caro, J., Pascual, A., Aranda, A. and Sarlieve, L (1988). Evidence for the presence of nuclear triiodothyronine receptors in secondary cultures of pure rat oligodendrocytes. Endocrin 122, 2278-2284.[Abstract]

Zhang, X., Wills, K. N., Husmann, M., Hermann, T. and Pfahl, M (1991). Novel pathway for thyroid hormone receptor action through interaction with jun and fos oncogene activites. Mol. Cell. Biol 11, 6016-6025.[Abstract/Free Full Text]

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[Abstract] [Full Text] [PDF]

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Oligodendrocyte precursor differentiation is perturbed in the absence of the cyclin-dependent kinase inhibitor�p27Kip1
Genes & Dev., September 15, 1997; 11(18): 2335 - 2346.
[Abstract] [Full Text] [PDF]

J. H. Oppenheimer and H. L. Schwartz
Molecular Basis of Thyroid Hormone-Dependent Brain Development
Endocr. Rev., August 1, 1997; 18(4): 462 - 475.
[Abstract] [Full Text] [PDF]

H. L. Schwartz, M. E. Ross, and J. H. Oppenheimer
Lack of Effect of Thyroid Hormone on Late Fetal Rat Brain Development
Endocrinology, August 1, 1997; 138(8): 3119 - 3124.
[Abstract] [Full Text] [PDF]

N. Takakura, H. Yoshida, Y. Ogura, H. Kataoka, S. Nishikawa, and S.-I. Nishikawa
PDGFR{alpha} Expression During Mouse Embryogenesis: Immunolocalization Analyzed by Whole-mount Immunohistostaining Using the Monoclonal Anti-mouse PDGFR{alpha} Antibody APA5
J. Histochem. Cytochem., June 1, 1997; 45(6): 883 - 894.
[Abstract] [Full Text] [PDF]

P. Knutson, C. A. Ghiani, J.-M. Zhou, V. Gallo, and C. J. McBain
K+ Channel Expression and Cell Proliferation Are Regulated by Intracellular Sodium and Membrane Depolarization in Oligodendrocyte Progenitor Cells
J. Neurosci., April 15, 1997; 17(8): 2669 - 2682.
[Abstract] [Full Text] [PDF]

K. A. Strait, D. J. Carlson, H. L. Schwartz, and J. H. Oppenheimer
Transient Stimulation of Myelin Basic Protein Gene Expression in Differentiating Cultured Oligodendrocytes: A Model for 3,5,3'-Triiodothyronine-Induced Brain Development
Endocrinology, February 1, 1997; 138(2): 635 - 641.
[Abstract] [Full Text] [PDF]

E. M. Tanaka, A. A.F. Gann, P. B. Gates, and J. P. Brockes
Newt Myotubes Reenter the Cell Cycle by Phosphorylation of the Retinoblastoma Protein
J. Cell Biol., January 13, 1997; 136(1): 155 - 165.
[Abstract] [Full Text] [PDF]

C. C. Thompson
Thyroid Hormone-Responsive Genes in Developing Cerebellum Include a Novel Synaptotagmin and a hairless Homolog
J. Neurosci., December 15, 1996; 16(24): 7832 - 7840.
[Abstract] [Full Text] [PDF]

K K Johe, T G Hazel, T Muller, M M Dugich-Djordjevic, and R D McKay
Single factors direct the differentiation of stem cells from the fetal and adult central nervous system.
Genes & Dev., December 15, 1996; 10(24): 3129 - 3140.
[Abstract] [PDF]

H. Zhang and R. H. Miller
Density-Dependent Feedback Inhibition of Oligodendrocyte Precursor Expansion
J. Neurosci., November 1, 1996; 16(21): 6886 - 6895.
[Abstract] [Full Text] [PDF]

				J. S. Espinosa and L. Luo Timing Neurogenesis and Differentiation: Insights from Quantitative Clonal Analyses of Cerebellar Granule Cells J. Neurosci., March 5, 2008; 28(10): 2301 - 2312. [Abstract] [Full Text] [PDF]

				C. A. Lyssiotis, J. Walker, C. Wu, T. Kondo, P. G. Schultz, and X. Wu Inhibition of histone deacetylase activity induces developmental plasticity in oligodendrocyte precursor cells PNAS, September 18, 2007; 104(38): 14982 - 14987. [Abstract] [Full Text] [PDF]

				Y. Chen, D. Tian, L. Ku, D. J. Osterhout, and Y. Feng The Selective RNA-binding Protein Quaking I (QKI) Is Necessary and Sufficient for Promoting Oligodendroglia Differentiation J. Biol. Chem., August 10, 2007; 282(32): 23553 - 23560. [Abstract] [Full Text] [PDF]

				J. C. Dugas, A. Ibrahim, and B. A. Barres A Crucial Role for p57Kip2 in the Intracellular Timer that Controls Oligodendrocyte Differentiation J. Neurosci., June 6, 2007; 27(23): 6185 - 6196. [Abstract] [Full Text] [PDF]

				Y. Zhang, Y.-T. Chen, S. Xie, L. Wang, Y.-F. Lee, S.-S. Chang, and C. Chang Loss of Testicular Orphan Receptor 4 Impairs Normal Myelination in Mouse Forebrain Mol. Endocrinol., April 1, 2007; 21(4): 908 - 920. [Abstract] [Full Text] [PDF]

				J. C. Dugas, Y. C. Tai, T. P. Speed, J. Ngai, and B. A. Barres Functional Genomic Analysis of Oligodendrocyte Differentiation J. Neurosci., October 25, 2006; 26(43): 10967 - 10983. [Abstract] [Full Text] [PDF]

				J. Sohn, J. Natale, L.-J. Chew, S. Belachew, Y. Cheng, A. Aguirre, J. Lytle, B. Nait-Oumesmar, C. Kerninon, M. Kanai-Azuma, et al. Identification of Sox17 as a transcription factor that regulates oligodendrocyte development. J. Neurosci., September 20, 2006; 26(38): 9722 - 9735. [Abstract] [Full Text] [PDF]

				S. Shen, J. Li, and P. Casaccia-Bonnefil Histone modifications affect timing of oligodendrocyte progenitor differentiation in the developing rat brain J. Cell Biol., May 23, 2005; 169(4): 577 - 589. [Abstract] [Full Text] [PDF]

				M. Xin, T. Yue, Z. Ma, F.-f. Wu, A. Gow, and Q. R. Lu Myelinogenesis and Axonal Recognition by Oligodendrocytes in Brain Are Uncoupled in Olig1-Null Mice J. Neurosci., February 9, 2005; 25(6): 1354 - 1365. [Abstract] [Full Text] [PDF]

				T. Kondo and M. Raff Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells Genes & Dev., December 1, 2004; 18(23): 2963 - 2972. [Abstract] [Full Text] [PDF]

				P. Zhang, J. Chebath, P. Lonai, and M. Revel Enhancement of Oligodendrocyte Differentiation from Murine Embryonic Stem Cells by an Activator of gp130 Signaling Stem Cells, May 1, 2004; 22(3): 344 - 354. [Abstract] [Full Text] [PDF]

				N. Billon, A. Terrinoni, C. Jolicoeur, A. McCarthy, W. D. Richardson, G. Melino, and M. Raff Roles for p53 and p73 during oligodendrocyte development Development, March 15, 2004; 131(6): 1211 - 1220. [Abstract] [Full Text] [PDF]

				M. NOBLE, J. SMITH, J. POWER, and M. MAYER-PROSCHEL Redox State as a Central Modulator of Precursor Cell Function Ann. N.Y. Acad. Sci., June 1, 2003; 991(1): 251 - 271. [Abstract] [Full Text] [PDF]

				M. Nygard, G. M. Wahlstrom, M. V. Gustafsson, Y. M. Tokumoto, and M. Bondesson Hormone-Dependent Repression of the E2F-1 Gene by Thyroid Hormone Receptors Mol. Endocrinol., January 1, 2003; 17(1): 79 - 92. [Abstract] [Full Text] [PDF]

				M. Marin-Husstege, M. Muggironi, A. Liu, and P. Casaccia-Bonnefil Histone Deacetylase Activity Is Necessary for Oligodendrocyte Lineage Progression J. Neurosci., December 1, 2002; 22(23): 10333 - 10345. [Abstract] [Full Text] [PDF]

				N. Billon, C. Jolicoeur, Q. L. Ying, A. Smith, and M. Raff Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells J. Cell Sci., September 15, 2002; 115(18): 3657 - 3665. [Abstract] [Full Text] [PDF]

				S. Genoud, C. Lappe-Siefke, S. Goebbels, F. Radtke, M. Aguet, S. S. Scherer, U. Suter, K.-A. Nave, and N. Mantei Notch1 control of oligodendrocyte differentiation in the spinal cord J. Cell Biol., August 19, 2002; 158(4): 709 - 718. [Abstract] [Full Text] [PDF]

				D. Baas, C. Legrand, J. Samarut, and F. Flamant Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors PNAS, February 20, 2002; (2002) 52482299. [Abstract] [Full Text] [PDF]

				N. Spassky, K. Heydon, A. Mangatal, A. Jankovski, C. Olivier, F. Queraud-Lesaux, C. Goujet-Zalc, J. L. Thomas, and B. Zalc Sonic hedgehog-dependent emergence of oligodendrocytes in the telencephalon: evidence for a source of oligodendrocytes in the olfactory bulb that is independent of PDGFR{alpha} signaling Development, December 15, 2001; 128(24): 4993 - 5004. [Abstract] [Full Text] [PDF]

				W. W. Li, C. Le Goascogne, M. Ramauge, M. Schumacher, M. Pierre, and F. Courtin Induction of Type 3 Iodothyronine Deiodinase by Nerve Injury in the Rat Peripheral Nervous System Endocrinology, December 1, 2001; 142(12): 5190 - 5197. [Abstract] [Full Text] [PDF]

				R. T. Ballock, X. Zhou, L. M. Mink, D. H. C. Chen, B. C. Mita, and M. C. Stewart Expression of Cyclin-Dependent Kinase Inhibitors in Epiphyseal Chondrocytes Induced to Terminally Differentiate with Thyroid Hormone Endocrinology, December 1, 2000; 141(12): 4552 - 4557. [Abstract] [Full Text] [PDF]

				T. Kondo and M. Raff Oligodendrocyte Precursor Cells Reprogrammed to Become Multipotential CNS Stem Cells Science, September 8, 2000; 289(5485): 1754 - 1757. [Abstract] [Full Text]

				B.-S. Li, L. Zhang, J. Gu, N. D. Amin, and H. C. Pant Integrin alpha 1beta 1-Mediated Activation of Cyclin-Dependent Kinase 5 Activity Is Involved in Neurite Outgrowth and Human Neurofilament Protein H Lys-Ser-Pro Tail Domain Phosphorylation J. Neurosci., August 15, 2000; 20(16): 6055 - 6062. [Abstract] [Full Text] [PDF]

				J. R. Chan, P. M. Rodriguez-Waitkus, B. K. Ng, P. Liang, and M. Glaser Progesterone Synthesized by Schwann Cells during Myelin Formation Regulates Neuronal Gene Expression Mol. Biol. Cell, July 1, 2000; 11(7): 2283 - 2295. [Abstract] [Full Text]

				M. Noble Precursor Cell Transitions in Oligodendrocyte Development J. Cell Biol., March 6, 2000; 148(5): 839 - 842. [Abstract] [Full Text] [PDF]

				D. G. Tang, Y. M. Tokumoto, and M. C. Raff Long-Term Culture of Purified Postnatal Oligodendrocyte Precursor Cells: Evidence for an Intrinsic Maturation Program that Plays out over Months J. Cell Biol., March 6, 2000; 148(5): 971 - 984. [Abstract] [Full Text] [PDF]

				T Kondo and M Raff Basic helix-loop-helix proteins and the timing of oligodendrocyte differentiation Development, January 7, 2000; 127(14): 2989 - 2998. [Abstract] [PDF]

				M. F. McManus, L.-C. Chen, I. Vallejo, and M. Vallejo Astroglial Differentiation of Cortical Precursor Cells Triggered by Activation of the cAMP-Dependent Signaling Pathway J. Neurosci., October 15, 1999; 19(20): 9004 - 9015. [Abstract] [Full Text] [PDF]

				O. Dammann and A. Leviton Brain Damage in Preterm Newborns: Might Enhancement of Developmentally Regulated Endogenous Protection Open a Door for Prevention? Pediatrics, September 1, 1999; 104(3): 541 - 550. [Abstract] [Full Text] [PDF]

				W. L. HUANG, L. D. BEAZLEY, J. A. QUINLIVAN, S. F. EVANS, J. P. NEWNHAM, and S. A. DUNLOP Effect of Corticosteroids on Brain Growth in Fetal Sheep Obstet. Gynecol., August 1, 1999; 94(2): 213 - 218. [Abstract] [Full Text] [PDF]