Negative regulation of the P0 gene in Schwann cells: suppression of P0 mRNA and protein induction in cultured Schwann cells by FGF2 and TGF beta 1, TGF beta 2 and TGF beta 3

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Morgan, L.
	Articles by Mirsky, R.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Morgan, L.
	Articles by Mirsky, R.

Archelos, J. J., Roggenbuck, K., Schneider-Schaulies, J., Linington, C., Toyka, K. V. and Hartung, H.-P (1993). Production and characterisation of monoclonal antibodies to the extracellular domain of Po. J. Neurosci. Res 35, 46-53.[Medline]

Bengal, E., Ransone, L., Scharfmann, R., Dwarki, V. J., Tapscott, S., Weintraub, H. and Verma, I. M (1992). Functional antagonism between c-jun and MyoD proteins: A direct physical association. Cell 68, 507-519.[Medline]

Bjursell, G. and Reichard, P (1973). Effects of thymidine on deoxyribonucleoside triphosphate pools and deoxyribonucleic acid synthesis in Chinese hamster ovary cells. J. Biol. Chem 248, 3904-3909.[Abstract/Free Full Text]

Brockes, J. P., Fields, K. L. and Raff, M. C (1979). Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve. Brain Res 165, 105-118.[Medline]

Brockes, J. P., Raff, M. C., Nishiguchi, D. J. and Winter, J (1980). Studies on cultured rat Schwann cells, III. Assays for peripheral myelin proteins. J. Neurocytol 9, 67-77.[Medline]

Brown, M. J. and Asbury, A. K (1981). Schwann cell proliferation in the postnatal mouse: timing and topography. Exp. Neurol 74, 170-186.[Medline]

Chomczynski, P. and Sacchi, N (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem 162, 156-159.[Medline]

Edmondson D. G. and Olson E. N (1993). Helix-loop-helix proteins as regulators of muscle-specific transcription. J. Biol. Chem 268, 755-758.[Free Full Text]

Fernandez-Valle, C., Fregien, N., Wood, P. M. and Bunge, M. B (1993). Expression of the protein zero myelin gene in axon-related Schwann cells is linked to basal lamina formation. Development 119, 867-880.[Abstract]

Flanders, K. C., Ludecke, G., Engels, S., Cissel, D. S., Roberts, A. B., Kondaiah, P., Lafyatis, R., Sporn, M. B. and Unsicker, K (1991). Localization and actions of transforming growth factor-s in the embryonic nervous system. Development 113, 183-191.[Abstract]

Friede, R. L. and Samorajski, T (1968). Myelin formation in the sciatic nerve of the rat. J. Neuropathol. Exp. Neurol 27, 546-570.[Medline]

Gonzalez, G. A., Menzel, P., Leonard, J., Fischer, W. H. and Montminy, M. R (1991). Characterization of motifs that are critical for activity of the cyclic AMP-responsive transcription factor CREB. Mol. Cell Biol 11, 1306-1312.[Abstract/Free Full Text]

Gratzner, H. G (1982). Monoclonal antibody to 5-bromo and 5 iododeoxy-uridine: a new agent for detection of DNA replication. Science 218, 474-475.[Abstract/Free Full Text]

Griffiths, I. R., Mitchell, L. S., McPhilemy, K., Morrison, S., Kyriakides, E. and Barrie, J. A (1989). Expression of myelin protein genes in Schwann cells. J. Neurocytol 18, 345-352.[Medline]

Gu, W., Schneider, J. W., Condorelli, G., Kaushal, S., Mahdavi, V. and Nadal-Ginard, B (1993). Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation. Cell 72, 309-324.[Medline]

He, X., Gerrero, R., Simmons, D. M., Park, R. E., Lin, C. J., Swanson, L. W. and Rosenfeld, M. G (1990). Tst-1, a member of the POU domain gene family, binds to the promoter of the gene encoding the cell surface adhesion molecule Po. Mol. Cell Biol 11, 1739-1744.

Hohmann, P., DenHaese, G. and Greene, R. S (1993). Mitotic CDC2 kinase is negatively regulated by cAMP-dependent kinase in mouse fibroblast cell free extracts. Cell Prolif 26, 195-204.[Medline]

Hu, J.-S. and Olson, E. N (1990). Functional receptors for transforming growth factor-are retained by biochemically differentiatied C2 myocytes in growth factor-deficient medium containing EGTA but down-regulated during terminal differentiation. J. Biol. Chem 265, 7914-7919.[Abstract/Free Full Text]

Jessen, K. R. and Mirsky, R (1991). Schwann cell precursors and their development. Glia 4, 9-18.

Jessen, K. R., Mirsky, R. and Morgan, L (1987). Myelinated, but not unmyelinated axons reversibly down-regulate N-CAM in Schwann cells. J. Neurocytol 16, 689-700.[Medline]

Jessen, K. R., Thorpe, R. and Mirsky, R (1984). Molecular identity, distribution and heterogeneity of glial fibrillary acidic protein: an immunoblotting and immunohistochemical study of Schwann cells, satellite cells, enteric glia and astrocytes. J. Neurocytol 13, 187-200.[Medline]

Kalcheim, C. and Neufeld, G (1990). Expression of basic fibroblast growth factor in the nervous system of early avian embryos. Development 109, 203-215.[Abstract]

Kamholz, J., Sessa, M., Scherer, S., Vogelbacker, H., Mokuno, K., Baron, P., Wrabetz, L., Shy, M. and Pleasure, D (1992). Structure and expression of proteolipid protein in the peripheral nervous system. J. Neurosci. Res 31, 231-244.[Medline]

Kramer, I. M., Koorneef, I., de Laat, S. W. and van der Eijnden-van Raaij, A. J. M (1991). TGF1 induces phophorylation of the cAMP response element binding protein in ML-CC164 cells. EMBO J 10, 1083-1089.[Medline]

Lemke, G. and Axel, R (1985). Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin. Cell 40, 501-508.[Medline]

Lemke, G. and Chao, M (1988). Axons regulate Schwann cell expression of the major myelin and NGF receptor genes. Development 102, 499-504.[Abstract]

Lemke, G., Lamar, E. and Patterson, J (1988). Isolation and analysis of the gene encoding the peripheral myelin protein zero. Neuron 1, 73-83.[Medline]

Li, L., Zhou, J., James, G., Heller-Harrison, R., Czech, M. P. and Olson, E. N (1992). FGF inactivates myogenic helix-loop-helix proteins through phosphorylation of a conserved protein kinase C site in their DNA binding domain. Cell 71, 1181-1194.[Medline]

Martin, J. R. and Webster, H. DeF (1973). Mitotic Schwann cells in developing nerve: their changes in shape, fine structure and axon relationships. Dev. Biol 32, 417-431.[Medline]

Massague, J (1990). The transforming growth factor-family. Ann. Rev. Cell Biol 6, 597-641.

Mews, M. and Meyer, M (1993). Modulation of Schwann cell phenotype by TGF1: inhibition of PomRNA expression and down-regulation of the low-affinity NGF receptor. Glia 8, 208-217.[Medline]

Mirsky, R., Dubois, C., Morgan, L. and Jessen, K. R (1990). Prenatal Schwann cell development: appearance of 04 differentiation antigen in rat embryo sciatic nerve and its regulation by axon-Schwann cell signals. Development 109, 105-116.[Abstract]

Mirsky, R., Winter, J., Abney, E. R., Pruss, R. M., Gavrilovic, J. and Raff, M. C (1980). Myelin-specific proteins and glycolipids in rat Schwann cells and oligodendrocytes in culture. J. Cell Biol 84, 483-494.[Abstract/Free Full Text]

Monuki, E. S., Kuhn, R. and Lemke, G (1993). Repression of the myelin Pogene by the POU transcription factor SCIP. Mech. Dev 42, 15-32.[Medline]

Monuki, E. S, Kuhn, R., Weinmaster, G., Trapp, B. D. and Lemke, G (1990). Expression and control of the POU transcription factor SCIP. Science 249, 1300-1303.[Abstract/Free Full Text]

Monuki, E. S., Weinmaster, G., Kuhn, R. and Lemke, G (1989). SCIP: a glial POU domain gene regulated by cyclic AMP. Neuron 3, 783-793.[Medline]

Morgan L., Jessen, K. R. and Mirsky, R (1991). The effects of cyclic AMP on differentiation of cultured Schwann cells: progression from an early phenotype (04+) to a myelin phenotype (Po+, GFAP, N-CAM+, NGF-receptor ) depends on growth inhibition. J. Cell Biol 112, 457-467.[Abstract/Free Full Text]

Moses, H. L., Yang, E. Y. and Pietenpol, J. A (1990). TGFstimulation and inhibition of cell proliferation: new mechanistic insights. Cell 63, 245-247.[Medline]

Neely, E. K., Beckers, M. W., Oh, Y., Cohen, P. and Rosenfeld, R. G (1991). Insulin-like growth factor receptors. Acta paediatr. Scand. (Suppl.) 372, 116-123.[Medline]

Olson, E. N (1992). Interplay between proliferation and differentiation within the myogenic lineage. Dev. Biol 154, 261-272.[Medline]

Olson, E. N., Sternberg, E., Hu, J. S., Spizz, G. and Wilcox, C (1986). Regulation of myogenic differentiation by typetransforming growth factor. J. Cell Biol 103, 1799-1805.[Abstract/Free Full Text]

Scherer, S. S., Kamholz, J. and Jakowlew, S. B (1993). Axons modulate the expression of transforming growth factor-betas in Schwann cells. Glia 8, 265-276.[Medline]

Schubert, D (1992). Synergistic interactions between transforming growthfactor beta and fibroblast growth factor regulate Schwann cell mitosis. J. Neurobiol 23, 143-148.[Medline]

Schumacher, M., Jung-Testas, I., Robel, P. and Baulieu, E.-E (1993). Insulin-like growth factor I: a mitogen for rat Schwann cells in the presence of elevated levels of cyclic AMP. Glia 8, 232-240.[Medline]

Sobue, G. and Pleasure, D (1984). Schwann cell galactocerebroside induced by derivatives of adenosine 3, 5 -monophosphate. Science 224, 72-74.[Abstract/Free Full Text]

Sobue, G., Shuman, S. and Pleasure, D (1986). Schwann cell responses to cyclic AMP: proliferation, change in shape, and appearance of surface galactocerebroside. Brain Res 362, 23-32.[Medline]

Spizz, G., Roman, D., Strauss, A. and Olson, E. N (1986). Serum and fibroblast growth factor inhibit myogenic differentiation through a mechanism dependent on protein synthesis and independent of cell proliferation. J. Biol. Chem 261, 9483-9488.[Abstract/Free Full Text]

Stewart, H. J. S., Eccleston, P. A., Jessen, K. R. and Mirsky, R (1991). Interaction between cAMP elevation, identified growth factors, and serum components regulating Schwann cell growth. J. Neurosci. Res 30, 346-352.[Medline]

Stewart, H. J. S., Morgan, L., Jessen, K. R. and Mirsky, R (1993). Changes in DNA synthesis rate in the Schwann cell lineage in vivo are correlated with the precursor-Schwann cell transition and myelination. Eur. J. Neurosci 5, 1136-1144.[Medline]

Tobey, R. A., Valdez, J. G. and Crissman, H. A (1988). Synchronization of human diploid fibroblasts at multiple stages of the cell cycle. Exp. Cell Res 179, 400-416.[Medline]

Trapp, B., Hauer, P. and Lemke, G (1988). Axonal regulation of myelin protein mRNA levels in actively myelinating Schwann cells. J. Neurosci 8, 3515-3521.[Abstract]

Trapp, B. D., Itoyama, Y., Sternberger, N. H., Quarles, R. H. and Webster, H. de F (1981). Immunocytochemical localization of Poprotein in Golgi complex membranes and myelin of developing rat Schwann cells. J. Cell Biol 90, 1-6.[Abstract/Free Full Text]

Unsicker. K., Flanders, K. C., Cissel, D. S., Lafyatis, R. and Sporn M. B (1991). Transforming growth factor beta isoforms in the rat central and peripheral nervous system. Neurosci 44, 613-625.[Medline]

Webster, H. DeF., Martin, J. R. and O'Connell, M. F (1973). The relationship between interphase Schwann cells and axons before myelination: a quantitative electron microscopic study. Dev. Biol 32, 401-416.[Medline]

Zentella, A. and Massague, J (1992). Transforming growth factorinduces myoblast differentiation in the presence of mitogens. Proc. Natl. Acad. Sci. USA 89, 5176-5180.[Abstract/Free Full Text]

This article has been cited by other articles:

D. B. Parkinson, A. Bhaskaran, P. Arthur-Farraj, L. A. Noon, A. Woodhoo, A. C. Lloyd, M. L. Feltri, L. Wrabetz, A. Behrens, R. Mirsky, et al.
c-Jun is a negative regulator of myelination
J. Cell Biol., May 19, 2008; 181(4): 625 - 637.
[Abstract] [Full Text] [PDF]

M. D'Antonio, A. Droggiti, M. L. Feltri, J. Roes, L. Wrabetz, R. Mirsky, and K. R. Jessen
TGFbeta Type II Receptor Signaling Controls Schwann Cell Death and Proliferation in Developing Nerves.
J. Neurosci., August 15, 2006; 26(33): 8417 - 8427.
[Abstract] [Full Text] [PDF]

D. B. Parkinson, A. Bhaskaran, A. Droggiti, S. Dickinson, M. D'Antonio, R. Mirsky, and K. R. Jessen
Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death
J. Cell Biol., February 2, 2004; 164(3): 385 - 394.
[Abstract] [Full Text] [PDF]

S. G. Slutsky, A. K. Kamaraju, A. M. Levy, J. Chebath, and M. Revel
Activation of Myelin Genes during Transdifferentiation from Melanoma to Glial Cell Phenotype
J. Biol. Chem., March 7, 2003; 278(11): 8960 - 8968.
[Abstract] [Full Text] [PDF]

A. Tabernero, A. Velasco, B. Granda, E. M. Lavado, and J. M. Medina
Transcytosis of Albumin in Astrocytes Activates the Sterol Regulatory Element-binding Protein-1, Which Promotes the Synthesis of the Neurotrophic Factor Oleic Acid
J. Biol. Chem., February 1, 2002; 277(6): 4240 - 4246.
[Abstract] [Full Text] [PDF]

D. B. Parkinson, Z. Dong, H. Bunting, J. Whitfield, C. Meier, H. Marie, R. Mirsky, and K. R. Jessen
Transforming Growth Factor beta (TGFbeta ) Mediates Schwann Cell Death In Vitro and In Vivo: Examination of c-Jun Activation, Interactions with Survival Signals, and the Relationship of TGFbeta -Mediated Death to Schwann Cell Differentiation
J. Neurosci., November 1, 2001; 21(21): 8572 - 8585.
[Abstract] [Full Text] [PDF]

G. Zanazzi, S. Einheber, R. Westreich, M.-J. Hannocks, D. Bedell-Hogan, M. A. Marchionni, and J. L. Salzer
Glial Growth Factor/Neuregulin Inhibits Schwann Cell Myelination and Induces Demyelination
J. Cell Biol., March 19, 2001; 152(6): 1289 - 1300.
[Abstract] [Full Text] [PDF]

T. ROSENBAUM, H. A. KIM, Y. L. BOISSY, B. LING, and N. RATNER
Neurofibromin, the Neurofibromatosis Type 1 Ras-GAP, Is Required for Appropriate P0 Expression and Myelination
Ann. N.Y. Acad. Sci., September 14, 1999; 883(1): 203 - 214.
[Abstract] [Full Text] [PDF]

H. S. Keirstead, T. Ben-Hur, B. Rogister, M. T. O'Leary, M. Dubois-Dalcq, and W. F. Blakemore
Polysialylated Neural Cell Adhesion Molecule-Positive CNS Precursors Generate Both Oligodendrocytes and Schwann Cells to Remyelinate the CNS after Transplantation
J. Neurosci., September 1, 1999; 19(17): 7529 - 7536.
[Abstract] [Full Text] [PDF]

D. E. Weinstein
Review : The Role of Schwann cells in Neural Regeneration
Neuroscientist, July 1, 1999; 5(4): 208 - 216.
[Abstract] [PDF]

C. Meier, E. Parmantier, A. Brennan, R. Mirsky, and K. R. Jessen
Developing Schwann Cells Acquire the Ability to Survive without Axons by Establishing an Autocrine Circuit Involving Insulin-Like Growth Factor, Neurotrophin-3, and Platelet-Derived Growth Factor-BB
J. Neurosci., May 15, 1999; 19(10): 3847 - 3859.
[Abstract] [Full Text] [PDF]

A. M. Brown and G. Lemke
Multiple Regulatory Elements Control Transcription of the Peripheral Myelin Protein Zero Gene
J. Biol. Chem., November 14, 1997; 272(46): 28939 - 28947.
[Abstract] [Full Text] [PDF]

C. Meisinger, C. Zeschnigk, and C. Grothe
In Vivo and in Vitro Effect of Glucocorticoids on Fibroblast Growth Factor (FGF)-2 and FGF Receptor 1Expression
J. Biol. Chem., July 12, 1996; 271(28): 16520 - 16525.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Morgan, L.

Articles by Mirsky, R.

Search for Related Content

PubMed

PubMed Citation

Articles by Morgan, L.

Articles by Mirsky, R.

				M. D'Antonio, A. Droggiti, M. L. Feltri, J. Roes, L. Wrabetz, R. Mirsky, and K. R. Jessen TGFbeta Type II Receptor Signaling Controls Schwann Cell Death and Proliferation in Developing Nerves. J. Neurosci., August 15, 2006; 26(33): 8417 - 8427. [Abstract] [Full Text] [PDF]

				D. B. Parkinson, A. Bhaskaran, A. Droggiti, S. Dickinson, M. D'Antonio, R. Mirsky, and K. R. Jessen Krox-20 inhibits Jun-NH2-terminal kinase/c-Jun to control Schwann cell proliferation and death J. Cell Biol., February 2, 2004; 164(3): 385 - 394. [Abstract] [Full Text] [PDF]

				S. G. Slutsky, A. K. Kamaraju, A. M. Levy, J. Chebath, and M. Revel Activation of Myelin Genes during Transdifferentiation from Melanoma to Glial Cell Phenotype J. Biol. Chem., March 7, 2003; 278(11): 8960 - 8968. [Abstract] [Full Text] [PDF]

				A. Tabernero, A. Velasco, B. Granda, E. M. Lavado, and J. M. Medina Transcytosis of Albumin in Astrocytes Activates the Sterol Regulatory Element-binding Protein-1, Which Promotes the Synthesis of the Neurotrophic Factor Oleic Acid J. Biol. Chem., February 1, 2002; 277(6): 4240 - 4246. [Abstract] [Full Text] [PDF]

				D. B. Parkinson, Z. Dong, H. Bunting, J. Whitfield, C. Meier, H. Marie, R. Mirsky, and K. R. Jessen Transforming Growth Factor beta (TGFbeta ) Mediates Schwann Cell Death In Vitro and In Vivo: Examination of c-Jun Activation, Interactions with Survival Signals, and the Relationship of TGFbeta -Mediated Death to Schwann Cell Differentiation J. Neurosci., November 1, 2001; 21(21): 8572 - 8585. [Abstract] [Full Text] [PDF]

				G. Zanazzi, S. Einheber, R. Westreich, M.-J. Hannocks, D. Bedell-Hogan, M. A. Marchionni, and J. L. Salzer Glial Growth Factor/Neuregulin Inhibits Schwann Cell Myelination and Induces Demyelination J. Cell Biol., March 19, 2001; 152(6): 1289 - 1300. [Abstract] [Full Text] [PDF]

				T. ROSENBAUM, H. A. KIM, Y. L. BOISSY, B. LING, and N. RATNER Neurofibromin, the Neurofibromatosis Type 1 Ras-GAP, Is Required for Appropriate P0 Expression and Myelination Ann. N.Y. Acad. Sci., September 14, 1999; 883(1): 203 - 214. [Abstract] [Full Text] [PDF]

				H. S. Keirstead, T. Ben-Hur, B. Rogister, M. T. O'Leary, M. Dubois-Dalcq, and W. F. Blakemore Polysialylated Neural Cell Adhesion Molecule-Positive CNS Precursors Generate Both Oligodendrocytes and Schwann Cells to Remyelinate the CNS after Transplantation J. Neurosci., September 1, 1999; 19(17): 7529 - 7536. [Abstract] [Full Text] [PDF]

				D. E. Weinstein Review : The Role of Schwann cells in Neural Regeneration Neuroscientist, July 1, 1999; 5(4): 208 - 216. [Abstract] [PDF]

				C. Meier, E. Parmantier, A. Brennan, R. Mirsky, and K. R. Jessen Developing Schwann Cells Acquire the Ability to Survive without Axons by Establishing an Autocrine Circuit Involving Insulin-Like Growth Factor, Neurotrophin-3, and Platelet-Derived Growth Factor-BB J. Neurosci., May 15, 1999; 19(10): 3847 - 3859. [Abstract] [Full Text] [PDF]

				A. M. Brown and G. Lemke Multiple Regulatory Elements Control Transcription of the Peripheral Myelin Protein Zero Gene J. Biol. Chem., November 14, 1997; 272(46): 28939 - 28947. [Abstract] [Full Text] [PDF]

				C. Meisinger, C. Zeschnigk, and C. Grothe In Vivo and in Vitro Effect of Glucocorticoids on Fibroblast Growth Factor (FGF)-2 and FGF Receptor 1Expression J. Biol. Chem., July 12, 1996; 271(28): 16520 - 16525. [Abstract] [Full Text] [PDF]