A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse

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Ang, S. and Rossant, J (1993). Anterior mesendoderm induces mouse Engrailed genes in explant cultures. Development 118, 139-149.[Abstract]

Beddington, R. S. P., Rashbass, P. and Wilson, V (1992). Brachyury -a gene affecting mouse gastrulation and early organogenesis. Development 1992, 157-165.

Beddington, R. S. P. and Smith, J. C (1993). Control of vertebrate gastrulation: inducing signals and responding genes. Curr. Opin. Genet. Dev 3, 655-661.[Medline]

Blum, M., Gaunt, S. J., Cho, K. W. Y., Steinbeisser, H., Bitten, D. and De Robertis, E. M (1992). Gastrulation in the mouse: the role of the homeobox gene goosecoid. Cell 69, 1097-1106.[Medline]

Burdsal, C. A., Damsky, C. H. and Pederson, R. A (1993). The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. Development 118, 829-844.[Abstract]

Candia, A. F., Hu, J., Crosby, J., Lalley, P. A., Noden, D., Nadeau, J. H. and Wright, C. V. E (1992). Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development 116, 1123-1136.[Abstract]

Cho, K. W. Y., Blumberg, B., Steinbeisser, H. and De Robertis, E. M (1991). Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.[Medline]

Conlon, F. L., Barth, K. S. and Robertson, E. J (1991). A novel retrovirally induced embryonic lethal mutation in the mouse: assessment of the developmental fate of embryonic stem cells homozygous for the 413.d proviral insertion. Development 111, 969-981.[Abstract/Free Full Text]

Downs, K. M. and Davies, T (1993). Staging of gastrulating mouse embryos by morphological landmarks in the dissecting microscope. Development 118, 1255-1266.[Abstract]

Faust, C. and Magnuson, T (1993). Genetic control of gastrulation in the mouse. Curr. Opin. Gen. Dev 3, 491-498.[Medline]

Frohman, M. A., Boyle, M. and Martin, G. R (1990). Isolation of the mouse hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm. Development 110, 589-608.[Abstract/Free Full Text]

Gamer, L. W. and Wright, C. V. E (1993). Murine Cdx-4 bears striking similarities to the drosophila caudal gene in its homeodomain and early expression pattern. Mech. Dev 43, 71-81.[Medline]

Green, J. B. A., New, H. V. and Smith, J. C (1992). Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of mesoderm. Cell 71, 731-739.[Medline]

Hashimoto K. and Nakatsuji, N (1989). Formation of the primitive streak and mesoderm cells in mouse embryos- detailed scanning electron microscopical study. Dev. Growth Diff 31, 209-218.

Hebert, J. M., Basilico, C., Goldfarb, M., Haub, O. and Martin, G. R (1990). Isolation of cDNAs encoding four mouse FGF family members and characterization of their expression patterns during embryogenesis. Dev. Biol 138, 454-463.[Medline]

Hemmati-Brivanlou, A. and Melton, D. A (1992). A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359, 609-614.[Medline]

Herrmann, B. G., Labeit, S., Poustka, A., King, T. R. and Lehrach, H (1990). Cloning of the T gene required in mesoderm formation in the mouse. Nature 343, 617-622.[Medline]

Holdener-Kenny, B., Sharan, S. K. and Magnuson, T (1992). Mouse albino deletion complex: from genetics to genes in development. BioEssays 14, 831-839.[Medline]

Iannaccone, P. M., Zhou, X., Khokha, M., Boucher, D. and Kuehn, M. R (1992). Insertional mutation of a gene involved in growth regulation of the early mouse embryo. Dev. Dynamics 194, 198-208.[Medline]

Izpisua-Belmonte, J. C., De Robertis, E. M., Storey, K. G. and Stern, C. D (1993). The homeobox gene goosecoid and the origin of organizer cells in the early chick blastoderm. Cell 74, 645-659.[Medline]

Jessell, T. M. and Melton, D. A (1992). Diffusible factors in vertebrate embryonic induction. Cell 68, 257-270.[Medline]

Kimelman, D., Christian, J. L. and Moon, R. T (1992). Synergistic1928principles of development: overlapping pattern systems in Xenopus mesoderm induction. Development 116, 1-9.[Abstract]

Lee, J. J., Radice, G., Perkins, C. P. and Costantini, F (1991). Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine H\24758 embryonic lethal transgene insertion. Development 115, 277-288.[Abstract]

Lyons, K. M., Pelton, R. W. and Hogan, B. L. M (1990). Organogenesis and pattern formation in the mouse: RNA distribution pattern suggest a role for bone morphogenetic protein-2A (BMP-2A). Development 109, 833-844.[Abstract/Free Full Text]

Lyons, K. M., Jones, C. M. and Hogan, B. L. M (1991). The DVR gene family in embryonic development. Trends Genet 7, 408-412.[Medline]

Massague, J (1990). The transforming growth factor beta family. Ann. Rev. Cell Biol 6, 597-641.

Matthews, K. A., Miller, D. B. and Kaufman, T (1990). Functional implication of the unusual spatial distribution of a minor-tubulin isotype in drosophila : a common thread among chordonal ligaments, developing muscle, and testis cyst cells. Dev. Biol 137, 171-183.[Medline]

Niehrs, C., Keller, R., Cho, K. W. Y. and De Robertis, E. M (1993). The homeobox gene goosecoid controls cell migration in Xenopus embryos. Cell 72, 491-503.[Medline]

Niswander, L. and Martin, G. R (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.[Abstract]

Poelmann, R. E (1981). The formation of the embryonic mesoderm in the early postimplantation mouse embryo. Anat. Embryol 162, 29-40.[Medline]

Rashbass, P., Cooke, L. A., Herrmann, B. G. and Beddington, R. S. P (1991). A cell autonomous function of Brachyury in T/T embryonic stem cell chimeras. Nature 353, 348-350.[Medline]

Robertson, E. J., Bradley, A., Kuehn, M. and Evans, M (1986). Germ line transmission of gene sequences introduced into cultured pluripotential cells by a retroviral vector. Nature 323, 445-448.[Medline]

Rosen, B. and Beddington, R. S. P (1993). Whole-mount in situ hybridization in the mouse embryo: gene expression in three dimensions. Trends Genet 9, 162-167.[Medline]

Ruiz i Altaba, A. and Melton, D. A (1989). Interaction between peptide growth factors and homeobox genes in the establishment of anterior-posterior polarity in frog embryos. Nature 341, 33-38.[Medline]

Sive, H. L (1993). The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus. Genes Dev 7, 1-12.[Free Full Text]

Wilkinson, D. G., Bhatt, S. and Herrmann, B. G (1990). Expression pattern of the mouse T gene and its role in mesoderm formation. Nature 343, 657-659.[Medline]

Wilson, V., Rashbass, P. and Beddington, R. S. P (1993). Chimeric analysis of T (Brachyury) gene function. Development 117, 1321-1331.[Abstract]

Wolf, C., Thisse, C., Stoetzel, C., Thisse, B., Gerlinger, P. and Perrin-Schmitt, F (1991). The M-twist gene of Mus is expressed in subsets of mesodermal cells and is closely related to the Xenopus X-twi and the Drosophila twist genes. Dev. Biol 143, 363-373.[Medline]

Zhou, X., Sasaki, H., Lowe, L., Hogan, B. L. M. and Kuehn, M. R (1993). Nodal is a novel TGF\247-like gene expressed in the mouse node during gastrulation. Nature 361, 543-547.[Medline]

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				S. Jia, Z. Ren, X. Li, Y. Zheng, and A. Meng smad2 and smad3 Are Required for Mesendoderm Induction by Transforming Growth Factor- /Nodal Signals in Zebrafish J. Biol. Chem., January 25, 2008; 283(4): 2418 - 2426. [Abstract] [Full Text] [PDF]

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				M. Takenaga, M. Fukumoto, and Y. Hori Regulated Nodal signaling promotes differentiation of the definitive endoderm and mesoderm from ES cells J. Cell Sci., June 15, 2007; 120(12): 2078 - 2090. [Abstract] [Full Text] [PDF]

				M. M. Shen Nodal signaling: developmental roles and regulation Development, March 15, 2007; 134(6): 1023 - 1034. [Abstract] [Full Text] [PDF]

				Y. Su, L. Zhang, X. Gao, F. Meng, J. Wen, H. Zhou, A. Meng, and Y.-G. Chen The evolutionally conserved activity of Dapper2 in antagonizing TGF-{beta} signaling FASEB J, March 1, 2007; 21(3): 682 - 690. [Abstract] [Full Text] [PDF]

				T. Dvash, N. Sharon, O. Yanuka, and N. Benvenisty Molecular Analysis of LEFTY-Expressing Cells in Early Human Embryoid Bodies Stem Cells, February 1, 2007; 25(2): 465 - 472. [Abstract] [Full Text] [PDF]

				K. Ogawa, A. Saito, H. Matsui, H. Suzuki, S. Ohtsuka, D. Shimosato, Y. Morishita, T. Watabe, H. Niwa, and K. Miyazono Activin-Nodal signaling is involved in propagation of mouse embryonic stem cells J. Cell Sci., January 1, 2007; 120(1): 55 - 65. [Abstract] [Full Text] [PDF]

				P. Gadue, T. L. Huber, P. J. Paddison, and G. M. Keller Wnt and TGF-beta signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells PNAS, November 7, 2006; 103(45): 16806 - 16811. [Abstract] [Full Text] [PDF]

				N. Scamuffa, F. Calvo, M. Chretien, N. G. Seidah, and A.-M. Khatib Proprotein convertases: lessons from knockouts FASEB J, October 1, 2006; 20(12): 1954 - 1963. [Abstract] [Full Text] [PDF]

				S. Tabibzadeh and A. Hemmati-Brivanlou Lefty at the Crossroads of "Stemness" and Differentiative Events Stem Cells, September 1, 2006; 24(9): 1998 - 2006. [Abstract] [Full Text] [PDF]

				R. L Jones, C. Stoikos, J. K Findlay, and L. A Salamonsen TGF-{beta} superfamily expression and actions in the endometrium and placenta. Reproduction, August 1, 2006; 132(2): 217 - 232. [Abstract] [Full Text] [PDF]

				D. Mesnard, M. Guzman-Ayala, and D. B. Constam Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning Development, July 1, 2006; 133(13): 2497 - 2505. [Abstract] [Full Text] [PDF]

				H. J. Rippon, J. M. Polak, M. Qin, and A. E. Bishop Derivation of Distal Lung Epithelial Progenitors from Murine Embryonic Stem Cells Using a Novel Three-Step Differentiation Protocol Stem Cells, May 1, 2006; 24(5): 1389 - 1398. [Abstract] [Full Text] [PDF]

				C. Chen, S. M. Ware, A. Sato, D. E. Houston-Hawkins, R. Habas, M. M. Matzuk, M. M. Shen, and C. W. Brown The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo Development, January 15, 2006; 133(2): 319 - 329. [Abstract] [Full Text] [PDF]

				J. R. Davenport and B. K. Yoder An incredible decade for the primary cilium: a look at a once-forgotten organelle Am J Physiol Renal Physiol, December 1, 2005; 289(6): F1159 - F1169. [Abstract] [Full Text] [PDF]

				D. Stickens, B. M. Zak, N. Rougier, J. D. Esko, and Z. Werb Mice deficient in Ext2 lack heparan sulfate and develop exostoses Development, November 15, 2005; 132(22): 5055 - 5068. [Abstract] [Full Text] [PDF]

				L. Vallier, M. Alexander, and R. A. Pedersen Activin/Nodal and FGF pathways cooperate to maintain pluripotency of human embryonic stem cells J. Cell Sci., October 1, 2005; 118(19): 4495 - 4509. [Abstract] [Full Text] [PDF]

				A. F. Cooper, K. P. Yu, M. Brueckner, L. L. Brailey, L. Johnson, J. M. McGrath, and A. E. Bale Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused Development, October 1, 2005; 132(19): 4407 - 4417. [Abstract] [Full Text] [PDF]

				V. Kouskoff, G. Lacaud, S. Schwantz, H. J. Fehling, and G. Keller Sequential development of hematopoietic and cardiac mesoderm during embryonic stem cell differentiation PNAS, September 13, 2005; 102(37): 13170 - 13175. [Abstract] [Full Text] [PDF]

				C. Suri, T. Haremaki, and D. C. Weinstein Xema, a foxi-class gene expressed in the gastrula stage Xenopus ectoderm, is required for the suppression of mesendoderm Development, June 15, 2005; 132(12): 2733 - 2742. [Abstract] [Full Text] [PDF]

				N. Shiraki, C.-J. Lai, Y. Hishikari, and S. Kume TGF-{beta} signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing endodermal cells Genes Cells, June 1, 2005; 10(6): 503 - 516. [Abstract] [Full Text] [PDF]

				T. A. Rodriguez, S. Srinivas, M. P. Clements, J. C. Smith, and R. S. P. Beddington Induction and migration of the anterior visceral endoderm is regulated by the extra-embryonic ectoderm Development, June 1, 2005; 132(11): 2513 - 2520. [Abstract] [Full Text] [PDF]

				G. Keller Embryonic stem cell differentiation: emergence of a new era in biology and medicine Genes & Dev., May 15, 2005; 19(10): 1129 - 1155. [Abstract] [Full Text] [PDF]

				E. S. Ng, L. Azzola, K. Sourris, L. Robb, E. G. Stanley, and A. G. Elefanty The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells Development, March 1, 2005; 132(5): 873 - 884. [Abstract] [Full Text] [PDF]

				Y.-L. Yan, J. Willoughby, D. Liu, J. G. Crump, C. Wilson, C. T. Miller, A. Singer, C. Kimmel, M. Westerfield, and J. H. Postlethwait A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development Development, March 1, 2005; 132(5): 1069 - 1083. [Abstract] [Full Text] [PDF]

				H. Jornvall, E. Reissmann, O. Andersson, M. Mehrkash, and C. F. Ibanez ALK7, a Receptor for Nodal, Is Dispensable for Embryogenesis and Left-Right Patterning in the Mouse Mol. Cell. Biol., November 1, 2004; 24(21): 9383 - 9389. [Abstract] [Full Text] [PDF]