The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD

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Structure and stability of the ankyrin domain of the Drosophila Notch receptor
Protein Sci., November 1, 2003; 12(11): 2622 - 2632.
[Abstract] [Full Text] [PDF]

H. Tsuji, H. Ishii-Ohba, H. Ukai, T. Katsube, and T. Ogiu
Radiation-induced deletions in the 5' end region of Notch1 lead to the formation of truncated proteins and are involved in the development of mouse thymic lymphomas
Carcinogenesis, July 1, 2003; 24(7): 1257 - 1268.
[Abstract] [Full Text] [PDF]

L. Espinosa, J. Ingles-Esteve, A. Robert-Moreno, and A. Bigas
Ikappa Balpha and p65 Regulate the Cytoplasmic Shuttling of Nuclear Corepressors: Cross-talk between Notch and NFkappa B Pathways
Mol. Biol. Cell, February 1, 2003; 14(2): 491 - 502.
[Abstract] [Full Text] [PDF]

A. E. Vernon and A. Philpott
A single cdk inhibitor, p27Xic1, functions beyond cell cycle regulation to promote muscle differentiation in Xenopus
Development, January 1, 2003; 130(1): 71 - 83.
[Abstract] [Full Text] [PDF]

K. G. Leong, X. Hu, L. Li, M. Noseda, B. Larrivee, C. Hull, L. Hood, F. Wong, and A. Karsan
Activated Notch4 Inhibits Angiogenesis: Role of {beta}1-Integrin Activation
Mol. Cell. Biol., April 15, 2002; 22(8): 2830 - 2841.
[Abstract] [Full Text] [PDF]

L. Espinosa, S. Santos, J. Ingles-Esteve, P. Munoz-Canoves, and A. Bigas
p65-NF{kappa}B synergizes with Notch to activate transcription by triggering cytoplasmic translocation of the nuclear receptor corepressor N-CoR
J. Cell Sci., March 15, 2002; 115(6): 1295 - 1303.
[Abstract] [Full Text] [PDF]

B. M. Jehn, I. Dittert, S. Beyer, K. von der Mark, and W. Bielke
c-Cbl Binding and Ubiquitin-dependent Lysosomal Degradation of Membrane-associated Notch1
J. Biol. Chem., March 1, 2002; 277(10): 8033 - 8040.
[Abstract] [Full Text] [PDF]

B. E. Berechid, M. Kitzmann, D. R. Foltz, A. H. Roach, D. Seiffert, L. A. Thompson, R. E. Olson, A. Bernstein, D. B. Donoviel, and J. S. Nye
Identification and Characterization of Presenilin-independent Notch Signaling
J. Biol. Chem., March 1, 2002; 277(10): 8154 - 8165.
[Abstract] [Full Text] [PDF]

K. Kumano, S. Chiba, K. Shimizu, T. Yamagata, N. Hosoya, T. Saito, T. Takahashi, Y. Hamada, and H. Hirai
Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression
Blood, December 1, 2001; 98(12): 3283 - 3289.
[Abstract] [Full Text] [PDF]

F. Oswald, B. Tauber, T. Dobner, S. Bourteele, U. Kostezka, G. Adler, S. Liptay, and R. M. Schmid
p300 Acts as a Transcriptional Coactivator for Mammalian Notch-1
Mol. Cell. Biol., November 15, 2001; 21(22): 7761 - 7774.
[Abstract] [Full Text] [PDF]

S. Zhou and S. D. Hayward
Nuclear Localization of CBF1 Is Regulated by Interactions with the SMRT Corepressor Complex
Mol. Cell. Biol., September 15, 2001; 21(18): 6222 - 6232.
[Abstract] [Full Text] [PDF]

E. Lamar, G. Deblandre, D. Wettstein, V. Gawantka, N. Pollet, C. Niehrs, and C. Kintner
Nrarp is a novel intracellular component of the Notch signaling pathway
Genes & Dev., August 1, 2001; 15(15): 1885 - 1899.
[Abstract] [Full Text] [PDF]

A. V. Gordadze, R. Peng, J. Tan, G. Liu, R. Sutton, B. Kempkes, G. W. Bornkamm, and P. D. Ling
Notch1IC Partially Replaces EBNA2 Function in B Cells Immortalized by Epstein-Barr Virus
J. Virol., July 1, 2001; 75(13): 5899 - 5912.
[Abstract] [Full Text] [PDF]

B. K. Hadland, N. R. Manley, D.-m. Su, G. D. Longmore, C. L. Moore, M. S. Wolfe, E. H. Schroeter, and R. Kopan
gamma -Secretase inhibitors repress thymocyte development
PNAS, June 19, 2001; 98(13): 7487 - 7491.
[Abstract] [Full Text] [PDF]

J. Zhang, H. Chen, G. Weinmaster, and S. D. Hayward
Epstein-Barr Virus BamHI-A Rightward Transcript-Encoded RPMS Protein Interacts with the CBF1-Associated Corepressor CIR To Negatively Regulate the Activity of EBNA2 and NotchIC
J. Virol., March 15, 2001; 75(6): 2946 - 2956.
[Abstract] [Full Text]

S. Tani, H. Kurooka, T. Aoki, N. Hashimoto, and T. Honjo
The N- and C-terminal regions of RBP-J interact with the ankyrin repeats of Notch1 RAMIC to activate transcription
Nucleic Acids Res., March 15, 2001; 29(6): 1373 - 1380.
[Abstract] [Full Text] [PDF]

E Hirsinger, P Malapert, J Dubrulle, M. Delfini, D Duprez, D Henrique, D Ish-Horowicz, and O Pourquie
Notch signalling acts in postmitotic avian myogenic cells to control MyoD activation
Development, January 1, 2001; 128(1): 107 - 116.
[Abstract] [PDF]

				S. Bai, R. Kopan, W. Zou, M. J. Hilton, C.-t. Ong, F. Long, F. P. Ross, and S. L. Teitelbaum NOTCH1 Regulates Osteoclastogenesis Directly in Osteoclast Precursors and Indirectly via Osteoblast Lineage Cells J. Biol. Chem., March 7, 2008; 283(10): 6509 - 6518. [Abstract] [Full Text] [PDF]

				X. Zheng, S. Linke, J. M. Dias, X. Zheng, K. Gradin, T. P. Wallis, B. R. Hamilton, M. Gustafsson, J. L. Ruas, S. Wilkins, et al. Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways PNAS, March 4, 2008; 105(9): 3368 - 3373. [Abstract] [Full Text] [PDF]

				A. M. Michie, A. C. Chan, M. Ciofani, M. Carleton, J. M. Lefebvre, Y. He, D. M. Allman, D. L. Wiest, J. C. Zuniga-Pflucker, and D. J. Izon Constitutive Notch signalling promotes CD4 CD8 thymocyte differentiation in the absence of the pre-TCR complex, by mimicking pre-TCR signals Int. Immunol., December 1, 2007; 19(12): 1421 - 1430. [Abstract] [Full Text] [PDF]

				P. S. Hodkinson, Paul. A. Elliott, Y. Lad, B. J. McHugh, A. C. MacKinnon, C. Haslett, and T. Sethi Mammalian NOTCH-1 Activates beta1 Integrins via the Small GTPase R-Ras J. Biol. Chem., September 28, 2007; 282(39): 28991 - 29001. [Abstract] [Full Text] [PDF]

				M.-Y. Kim, E.-J. Ann, J.-Y. Kim, J.-S. Mo, J.-H. Park, S.-Y. Kim, M.-S. Seo, and H.-S. Park Tip60 Histone Acetyltransferase Acts as a Negative Regulator of Notch1 Signaling by Means of Acetylation Mol. Cell. Biol., September 15, 2007; 27(18): 6506 - 6519. [Abstract] [Full Text] [PDF]

				H. Sun, L. Li, C. Vercherat, N. T. Gulbagci, S. Acharjee, J. Li, T.-K. Chung, T. H. Thin, and R. Taneja Stra13 regulates satellite cell activation by antagonizing Notch signaling J. Cell Biol., May 21, 2007; 177(4): 647 - 657. [Abstract] [Full Text] [PDF]

				E. Vasyutina, D. C. Lenhard, H. Wende, B. Erdmann, J. A. Epstein, and C. Birchmeier RBP-J (Rbpsuh) is essential to maintain muscle progenitor cells and to generate satellite cells PNAS, March 13, 2007; 104(11): 4443 - 4448. [Abstract] [Full Text] [PDF]

				K. Kondoh, K. Sunadome, and E. Nishida Notch Signaling Suppresses p38 MAPK Activity via Induction of MKP-1 in Myogenesis J. Biol. Chem., February 2, 2007; 282(5): 3058 - 3065. [Abstract] [Full Text] [PDF]

				K. Schuster-Gossler, R. Cordes, and A. Gossler Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants PNAS, January 9, 2007; 104(2): 537 - 542. [Abstract] [Full Text] [PDF]

				E. Dyczynska, D. Sun, H. Yi, A. Sehara-Fujisawa, C. P. Blobel, and A. Zolkiewska Proteolytic Processing of Delta-like 1 by ADAM Proteases J. Biol. Chem., January 5, 2007; 282(1): 436 - 444. [Abstract] [Full Text] [PDF]

				C. Bohm, N. M. Seibel, B. Henkel, H. Steiner, C. Haass, and W. Hampe SorLA Signaling by Regulated Intramembrane Proteolysis J. Biol. Chem., May 26, 2006; 281(21): 14547 - 14553. [Abstract] [Full Text] [PDF]

				H. Shen, A. S. McElhinny, Y. Cao, P. Gao, J. Liu, R. Bronson, J. D. Griffin, and L. Wu The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis Genes & Dev., March 15, 2006; 20(6): 675 - 688. [Abstract] [Full Text] [PDF]

				C. Hu, A. Dievart, M. Lupien, E. Calvo, G. Tremblay, and P. Jolicoeur Overexpression of Activated Murine Notch1 and Notch3 in Transgenic Mice Blocks Mammary Gland Development and Induces Mammary Tumors Am. J. Pathol., March 1, 2006; 168(3): 973 - 990. [Abstract] [Full Text] [PDF]

				T Haritunians, T Chow, R P J De Lange, J T Nichols, D Ghavimi, N Dorrani, D M St Clair, G Weinmaster, and C Schanen Functional analysis of a recurrent missense mutation in Notch3 in CADASIL J. Neurol. Neurosurg. Psychiatry, September 1, 2005; 76(9): 1242 - 1248. [Abstract] [Full Text] [PDF]

				S. J. Tapscott The circuitry of a master switch: Myod and the regulation of skeletal muscle gene transcription Development, June 15, 2005; 132(12): 2685 - 2695. [Abstract] [Full Text] [PDF]

				L. Pan, S. T. Glenn, C. A. Jones, and K. W. Gross Activation of the Rat Renin Promoter by HOXD10{middle dot}PBX1b{middle dot}PREP1, Ets-1, and the Intracellular Domain of Notch J. Biol. Chem., May 27, 2005; 280(21): 20860 - 20866. [Abstract] [Full Text] [PDF]

				P. Hayward, K. Brennan, P. Sanders, T. Balayo, R. DasGupta, N. Perrimon, and A. M. Arias Notch modulates Wnt signalling by associating with Armadillo/{beta}-catenin and regulating its transcriptional activity Development, April 15, 2005; 132(8): 1819 - 1830. [Abstract] [Full Text] [PDF]

				S. Azmi, A. Ozog, and R. Taneja Sharp-1/DEC2 Inhibits Skeletal Muscle Differentiation through Repression of Myogenic Transcription Factors J. Biol. Chem., December 10, 2004; 279(50): 52643 - 52652. [Abstract] [Full Text] [PDF]

				M. Le Gall and E. Giniger Identification of Two Binding Regions for the Suppressor of Hairless Protein within the Intracellular Domain of Drosophila Notch J. Biol. Chem., July 9, 2004; 279(28): 29418 - 29426. [Abstract] [Full Text] [PDF]

				N. Gupta-Rossi, E. Six, O. LeBail, F. Logeat, P. Chastagner, A. Olry, A. Israel, and C. Brou Monoubiquitination and endocytosis direct {gamma}-secretase cleavage of activated Notch receptor J. Cell Biol., July 5, 2004; 166(1): 73 - 83. [Abstract] [Full Text] [PDF]

				N. Tanimizu and A. Miyajima Notch signaling controls hepatoblast differentiation by altering the expression of liver-enriched transcription factors J. Cell Sci., July 1, 2004; 117(15): 3165 - 3174. [Abstract] [Full Text] [PDF]

				W. F. Leise III and P. R. Mueller Inhibition of the cell cycle is required for convergent extension of the paraxial mesoderm during Xenopus neurulation Development, April 15, 2004; 131(8): 1703 - 1715. [Abstract] [Full Text] [PDF]

				J. Chu and E. H. Bresnick Evidence That C Promoter-binding Factor 1 Binding Is Required for Notch-1-mediated Repression of Activator Protein-1 J. Biol. Chem., March 26, 2004; 279(13): 12337 - 12345. [Abstract] [Full Text] [PDF]

				M.-C. Delfini and D. Duprez Ectopic Myf5 or MyoD prevents the neuronal differentiation program in addition to inducing skeletal muscle differentiation, in the chick neural tube Development, February 15, 2004; 131(4): 713 - 723. [Abstract] [Full Text] [PDF]

				L. A. Timmerman, J. Grego-Bessa, A. Raya, E. Bertran, J. M. Perez-Pomares, J. Diez, S. Aranda, S. Palomo, F. McCormick, J. C. Izpisua-Belmonte, et al. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation Genes & Dev., January 1, 2004; 18(1): 99 - 115. [Abstract] [Full Text] [PDF]

				C. Dahlqvist, A. Blokzijl, G. Chapman, A. Falk, K. Dannaeus, C. F. Ibanez, and U. Lendahl Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation Development, December 15, 2003; 130(24): 6089 - 6099. [Abstract] [Full Text] [PDF]

				L. C. Murtaugh, B. Z. Stanger, K. M. Kwan, and D. A. Melton Notch signaling controls multiple steps of pancreatic differentiation PNAS, December 9, 2003; 100(25): 14920 - 14925. [Abstract] [Full Text] [PDF]

				A. Blokzijl, C. Dahlqvist, E. Reissmann, A. Falk, A. Moliner, U. Lendahl, and C. F. Ibanez Cross-talk between the Notch and TGF-{beta} signaling pathways mediated by interaction of the Notch intracellular domain with Smad3 J. Cell Biol., November 24, 2003; 163(4): 723 - 728. [Abstract] [Full Text] [PDF]

				M. E. Zweifel, D. J. Leahy, F. M. Hughson, and D. Barrick Structure and stability of the ankyrin domain of the Drosophila Notch receptor Protein Sci., November 1, 2003; 12(11): 2622 - 2632. [Abstract] [Full Text] [PDF]

				H. Tsuji, H. Ishii-Ohba, H. Ukai, T. Katsube, and T. Ogiu Radiation-induced deletions in the 5' end region of Notch1 lead to the formation of truncated proteins and are involved in the development of mouse thymic lymphomas Carcinogenesis, July 1, 2003; 24(7): 1257 - 1268. [Abstract] [Full Text] [PDF]