Neurofibromin-deficient fibroblasts fail to form perineurium in vitro

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Barbacid, M (1987). ras genes. Annu. Rev. Biochem 56, 779-827.[Medline]

Basu, T. N., Gutmann, D. H., Fletcher, J. A., Glover. T. W., Collins, F. S. and Downward, J (1992). Aberrant regulation of ras proteins in malignant tumour cells from type 1 neurofibromatosis patients. Nature 356, 713-715.[Medline]

Bolande, R. P (1974). The neurocristopathies: a unifying concept of disease arising in neural crest maldevelopment. Hum. Pathol 5, 409-429.

Bottenstein, J. and Sato, G. H (1979). Growth of a neuroblastoma cell line in serum free supplemented medium. Proc. Natn. Acad. Sci. USA 76, 514-517.[Abstract/Free Full Text]

Brannan, C. I., Perkins, A. S., Vogel, K. S., Ratner, N., Nordlund, M. L., Reid, S. W., Buchberg, A. M., Jenkins, N. A., Parada, L. F., and Copeland, N. G (1994). Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. Genes Development 8, 1019-1029.[Abstract/Free Full Text]

Brockes, J. P., Fields, K. L. and Raff, M. C (1979). Studies on cultured rat Schwann cells. I. Establishment of purified populations from cultures of peripheral nerve. Brain Res 165, 105-118.[Medline]

Buchberg, A. M., Cleveland, L. S., Jenkins, N. A. and Copeland, N. G (1990). Sequence homology shared by neurofibromatosis type-1 gene and IRA-1 and IRA-2 negative regulators of the RAS cyclic AMP pathway. Nature 347, 291-294.[Medline]

Bunge, M. B., Williams, A. K., Wood, P. M., Uitto, J. and Jeffrey, J. J (1980). Comparison of nerve cell and nerve cell plus Schwann cell cultures, with particular emphasis on basal lamina and collagen formation. J. Cell Biol 84, 184-202.[Abstract/Free Full Text]

Bunge, R. P. and Bunge, M. B (1983). Interrelationship between Schwann cell function and extracellular matrix production. Trends Neurosci 6, 11-.

Bunge, M. B., Wood, P. M., Tynan, L. B., Bates, M. L. and Sanes, J. R (1989). Perineurium originates from fibroblasts: demonstration in vitro with a retroviral marker. Science 243, 229-231.[Abstract/Free Full Text]

Cawthon, R. M., Weiss, R., Xu, G., Viskochil, D., Culver, M., Stevens, J., Robertson, M., Dunn, D., Gesteland, R., O'Connell, P. and White, R (1990). A major segment of the neurofibromatosis type 1 gene: cDNA sequence , genomic structure,and point mutations. Cell 62, 193-201.[Medline]

Daston, M. M., Scrable, H., Nordlund, M., Sturbaum, A. K., Nissen, L. M. and Ratner, N (1992). The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes. Neuron 8, 415-428.[Medline]

DeClue, J. E., Cohen, B. D. and Lowy, D. R (1991). Identification and characterization of the neurofibromatosis type 1 protein product. Proc. Natl. Acad. Sci. USA 88, 9914-9918.[Abstract/Free Full Text]

DeClue, J. E., Papageorge, A. G., Fletcher, J. A., Diehl, S. R., Ratner, N., Vass, W. C. and Lowy, D. R (1992). Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis. Cell 69, 265-273.[Medline]

Easton, D. F., Ponder, M. A., Huson, S. M. and Ponder, B. A. J (1993). An analysis of variation in expression of NF1: evidence for modifying genes. Am. J. Hum. Genet 53, 305-313.[Medline]

Eldridge, C. F., Bunge, M. B., Bunge, R. P. and Wood, P. M (1987). Differentiation of axon-related Schwann cells in vitro. I. Ascorbic acid regulates basal lamina assembly and myelin formation. J. Cell Biol 105, 1023-34.[Abstract/Free Full Text]

Fisher, E. R. and Vuzevski, V. D (1968). Cytogenesis of schwannoma (neurilemoma), neurofibroma, dermatofibroma, and dermatofibrosarcoma as revealed by electron microscopy. Am. J. Clin. Pathol 49, 141-154.[Medline]

Gamble, H. J. and Eames, R. A (1964). An electron microscope study of the connective tissues of human peripheral nerve. J. Anat 98, 655-.[Medline]

Golubic, M., Roudebush, M., Dobrowolski, S., Wolfman, A. and Stacey, D. W (1992). Catalytic properties, tissue and intracellular distribution of neurofibromin. Oncogene 7, 2151-2160.[Medline]

Gutmann, D. H., Wood, D. L. and Collins, F. S (1991). Identification of the neurofibromatosis type 1 gene product. Proc. Natl. Acad. Sci. USA 88, 9658-9662.[Abstract/Free Full Text]

Hayashi, S., Kubota, Y., Shimada, S. and Hori, Y (1990). Characterization of cultured neurofibroma cells derived from von Recklinghausen's disease. Clin. Exp. Dermatol 15, 217-221.[Medline]

Hirose, T. and Hizawa, K (1986). Ultrastructural localization of S-100 protein in neurofibroma. Acta neuropathol. (Berl) 69, 103-110.[Medline]

Huynh, D. P., Nechiporuk, T. and Pulst, S. M (1994). Differential expression and tissue distribution of type I and type II neurofibromins during mouse fetal development. Dev. Biol 161, 538-551.[Medline]

Jacks, T., Shih, T. S., Schmitt, E. M., Bronson, R. T., Bernards, A., Weinberg, R. A (1994). Tumour predisposition in mice heterozygous for a targeted mutation in Nf1. Nature Genet 7, 353-361.[Medline]

Johnson, M. R., DeClue, J. E., Felzmann, S., Vass, W. C., Xu, G., White, R. and Lowy, D. R (1994). Neurofibromin can inhibit ras-dependent growth by a mechanism independent of its GTPase-accelerating function. Mol. Cell. Biol 14, 641-645.[Abstract/Free Full Text]

Kadono, T., Soma, Y., Takehara, K., Nakagawa, H., Ishibasi, Y. and Kikuchi, K (1994). The growth regulation of neurofibroma cells in neurofibromatosis type-1: increased responses to PDGF-BB and TGF-b1. Biochem. Biophys. Res. Commun 198, 827-834.[Medline]

Kaila, T., Penttinen, R. and Peltonen, J (1988). Cultured neurofibromatosis tumor fibroblasts lack beta-adrenergic receptors. Neurofibromatosis 1, 37-42.[Medline]

Kim, H. A., Rosenbaum, T., Marchioni, M. A., Ratner, N. and DeClue, J. E (1995). Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes. Oncogene 11, 325-335.[Medline]

Krone, W., Zorlein, S. and Mao, R (1981). Cell culture studies on Neurofibromatosis (von Recklinghausen). I. Comparative growth experiments with fibroblasts at high and low concentrations of fetal calf serum. Hum. Genet 58, 188-193.[Medline]

Laird, P. W., Zijderveld, A., Linders, K., Rudnicki, M. A., Jaenisch, R. and Berns, A (1991). Simplified mammalian DNA isolation procedure. Nucleic Acids Res 19, 4293-.[Free Full Text]

Marchuk, D. A., Saulino, A. M., Tavakkol, R. L., Swaroop, M., Wallace, M. R., Andersen, L. B., Mitchell, A. L., Gutmann, D. H., Boguski, M. and Collins, F (1991). cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product. Genomics 11, 931-940.[Medline]

Marshall, C. J (1991). Tumor suppressor genes. Cell 64, 313-326.[Medline]

McCormick, F (1994). Activators and effectors of ras p21 proteins. Curr. Op. Gen. Dev 4, 71-76.[Medline]

Menon, A. G., Anderson, K. M., Riccardi, V. M., Chung, R. Y., Whaley, J. M., Yandell, D. E., Freiman, R. N., Lee, J. K., Li, F. P., Barker, D. F., Ledbetter, D. H., Klelcer, A., Martuza, R. L., Gusella, J. R. and Seizinger, B. R (1990). Chromosome 17p deletions and p53 mutations associated with the formation of malignant neurofibromasarcomas in von Recklinghausen neurofibromatosis. Proc. Natl. Acad. Sci. USA 87, 5435-5439.[Abstract/Free Full Text]

Moya, F., Bunge, M. B. and Bunge, R. P (1980). Schwann cells proliferate but fail to differentiate in defined medium. Proc. Natl. Acad. Sci. USA 77, 6902-6906.[Abstract/Free Full Text]

Murray, M. R., Stout, A. P. and Bradley, C. F (1941). Schwann cell versus fibroblasts as the origin of the specific nerve sheath tumor. Am. J. Pathol 16, 41-60.

Nakajima, T., Watanabe, S., Sato, Y., Kameya, T., Hirota, T. and Shimosato, Y (1982). An immunoperoxidase study of S-100 protein distribution in normal and neoplastic tissues. Am J Surg Pathol 6, 1982-.

Obremski, V. J., Johnson, M. I. and Bunge, M. B (1993). Fibroblasts are required for Schwann cell basal lamina deposition and ensheathment of unmyelinated sympathetic neurites in culture. J. Neurocytol 22, 102-117.[Medline]

Obremski, V. J., Wood, P. M. and Bunge, M. B (1993). Fibroblasts promote Schwann cell basal lamina deposition and elongation in the absence of neurons in culture. Dev. Biol 160, 119-134.[Medline]

Peltonen, J., Foidart, J.-M. and Aho, H. J (1984). Type IV and V collagens in von Recklinghausen's neurofibromas. An immunohistochemical and electrophoretical study. Virchows Arch [B] 47, 291-.[Medline]

Peltonen, J., Aho, H., Halme, T., Nanto-Salonen, K., Lehto, M., Foidart, J.-M., Duance, V., Vaheri, A. and Penttinen, R (1984). Distribution of different collagen types and fibronectin in neurofibromatosis tumours. Acta. path. microbiol. immunol. scand. Sect. A 92, 345-352.[Medline]

Peltonen, J., Nanto-Salonen, K., Aho, H. J., Kouri, T., Virtanen, I. and Penttinen, R (1984). Neurofibromatosis tumor and skin cells in culture. Acta Neuropathol. (Berl) 63, 269-275.[Medline]

Peltonen, J., Jaakola, S. and Lebwohl, M (1988). Cellular differentiation and expression of matrix genes in type 1 neurofibromatosis. Lab. Invest 59, 760-771.[Medline]

Riccardi, V. M (1981). Von Recklinghausen neurofibromatosis. N. Engl. J. Med 305, 1617-1627.[Medline]

Satoh, T. and Kaziro, Y (1992). Ras in signal transduction. Sem. Cancer Biol 3, 169-177.[Medline]

Sheela, S., Riccardi, V. M. and Ratner, N (1990). Angiogenic and invasive properties of neurofibroma Schwann cells. J. Cell Biol 111, 645-653.[Abstract/Free Full Text]

Skuse, G. R., Kosciolek, B. A. and Rowley, P. T (1991). The neurofibroma in von Recklinghausen neurofibromatosis has a unicelluar origin. Am. J. Hum. Genet 49, 600-607.[Medline]

Stefansson, K., Wollmann, R. and Jerkovic, M (1982). S-100 protein in soft tissue tumours derived from Schwann cells and melanocytes. Am. J. Pathol 106, 261-8.[Abstract]

Tanaka, K., Nakafuku, M., Satoh, T., Marshall, M., Gibbs, J., Matsumoto, K., Kaziro, Y. and Toh-e, A (1990). S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein. Cell 60, 803-807.[Medline]

Trahey, M. and McCormick, F (1987). A cytoplasmic protein stimulates normal N- ras p21 GTPase, but does not affect oncogenic mutants. Science 238, 542-545.[Abstract/Free Full Text]

Ushigome, S., Takakuwa, T., Hyuga, M., Tadokoro, M. and Shinagawa, T (1986). Perineurial cell tumor and the significance of the perineurial cells in neurofibroma. Acta Pathol. Jpn 36, 973-987.[Medline]

Viskochil, D., Buchberg, A. M., Xu, G., Cawthon, R. M., Stevens, J., Wolff, R. K., Culver, M., Carey, J. C., Copeland, N. G., Jenkins, N. A., White, R. and O'Connell, P (1990). Deletions and a translocation interrupt a cloned gene at the neurofibromatosis type 1 locus. Cell 62, 187-192.[Medline]

Waggener, J. D (1966). Ultrastructure of benign peripheral nerve sheath tumours. Cancer 19, 699-709.[Medline]

Wallace, M. R., Marchuk, D. A., Andersen, L. B., Letcher, R., Odeh, H. M., Saulino, A. M., Fountain, J. W., Brereton, A., Nicholson, J., Mitchell, A. L., Brownstein, B. H. and Collins, F. S (1990). Type 1 neurofibromatosis gene: Identification of a large transcript disrupted in three NF1 patients. Science 249, 181-186.[Abstract/Free Full Text]

Williams, A. K., Bunge, M. B. and Wood, P. M (1982). The development of perineurium in culture. J. Cell Biol 95, 2-.

Williams, A. K., Bunge, M. B., Wood, P. M. and Argiro, V (1983). Differences in collagen fibrils formed by fibroblasts (Fbs) from different sources with or without neurons (NCs) and Schwann cells (SCs). J. Cell Biol 97, 89-.

Wood, P. M. and Bunge, R. P (1975). Evidence that sensory axons are mitogenic for Schwann cells. Nature 256, 662-664.[Medline]

Wood, P. M (1976). Separation of functional Schwann cells and neurons from normal peripheral nerve tissue. Brain Res 155, 361-375.

Xu, G., O'Connell, P., Viskochil, D., Cawthon, R., Robertson, M., Culver, M., Dunn, D., Stevens, J., Gesteland, R., White, R. and Weiss, R (1990). The neurofibromatosis type 1 gene encodes a protein related to GAP. Cell 62, 599-608.[Medline]

Xu, G., Lin, B., Tanaka, K., Dunn, D., Wood, D., Gesteland, R., White, R., Weiss, R. and Tamanoi, F (1990). The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements IRA mutants of S. cerevisiae. Cell 63, 835-841.[Medline]

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				Y. Zhu, T. Harada, L. Liu, M. E. Lush, F. Guignard, C. Harada, D. K. Burns, M. L. Bajenaru, D. H. Gutmann, and L. F. Parada Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation Development, December 15, 2005; 132(24): 5577 - 5588. [Abstract] [Full Text] [PDF]

				A. Kurtz and R. L. Martuza Review Article : Antiangiogenesis in Neurofibromatosis 1 J Child Neurol, August 1, 2002; 17(8): 578 - 584. [Abstract] [PDF]

				Y. Zhu, M. I. Romero, P. Ghosh, Z. Ye, P. Charnay, E. J. Rushing, J. D. Marth, and L. F. Parada Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain Genes & Dev., April 1, 2001; 15(7): 859 - 876. [Abstract] [Full Text]

				E. Serra, T. Rosenbaum, U. Winner, R. Aledo, E. Ars, X. Estivill, H.-G. Lenard, and C. Lazaro Schwann cells harbor the somatic NF1 mutation in neurofibromas: evidence of two different Schwann cell subpopulations Hum. Mol. Genet., December 1, 2000; 9(20): 3055 - 3064. [Abstract] [Full Text] [PDF]

				J. L. Rutkowski, K. Wu, D. H. Gutmann, P. J. Boyer, and E. Legius Genetic and cellular defects contributing to benign tumor formation in neurofibromatosis type 1 Hum. Mol. Genet., April 12, 2000; 9(7): 1059 - 1066. [Abstract] [Full Text] [PDF]

				M. Lampisuo, J. Liippo, O. Vainio, K. M. McNagny, J. Kulmala, and O. Lassila Characterization of prethymic progenitors within the chicken embryo Int. Immunol., January 1, 1999; 11(1): 63 - 69. [Abstract] [Full Text] [PDF]

				T. Rosenbaum, K. M. Patrie, and N. Ratner Neurofibromatosis Type 1: Genetic and Cellular Mechanisms of Peripheral Nerve Tumor Formation Neuroscientist, November 1, 1997; 3(6): 412 - 420. [Abstract] [PDF]

				L. S. Sherman, R. Atit, T. Rosenbaum, A. D. Cox, and N. Ratner Single Cell Ras-GTP Analysis Reveals Altered Ras Activity in a Subpopulation of Neurofibroma Schwann Cells but Not Fibroblasts J. Biol. Chem., September 22, 2000; 275(39): 30740 - 30745. [Abstract] [Full Text] [PDF]

				K. K. Hiatt, D. A. Ingram, Y. Zhang, G. Bollag, and D. W. Clapp Neurofibromin GTPase-activating Protein-related Domains Restore Normal Growth in Nf1-/- Cells J. Biol. Chem., March 2, 2001; 276(10): 7240 - 7245. [Abstract] [Full Text] [PDF]