FGF-8 isoforms activate receptor splice forms that are expressed in mesenchymal regions of mouse development

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by MacArthur, C. A.
	Articles by Ornitz, D. M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by MacArthur, C. A.
	Articles by Ornitz, D. M.

Amaya, E., Musci, T. J. and Kirschner, M. W (1991). Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.[Medline]

Basilico, C. and Moscatelli, D (1992). The FGF family of growth factors and oncogenes. Adv. Cancer Res 59, 115-165.[Medline]

Bellosta, P., Talarico, D., Rogers, D. and Basilico, C (1993). Cleavage of K-FGF produces a truncated molecule with increased biological activity and receptor binding affinity. J. Cell Biol 121, 705-713.[Abstract/Free Full Text]

Burrus, L. W. and Olwin, B. B (1989). Isolation of a receptor for acidic and basic fibroblast growth factor from embryonic chick. J. Biol. Chem 264, 18647-18653.[Abstract/Free Full Text]

Chellaiah, A., McEwen, D. G., Werner, S., Xu, J. and Ornitz, D. M (1994). Fibroblast growth factor receptor 3: alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1. J. Biol. Chem 269, 11620-11627.[Abstract/Free Full Text]

Chomczynski, P. and Sacchi, N (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analyt. Biochem 162, 156-159.[Medline]

Cohn, M. J., Ispisz\234a-Belmonte, J. C., Abud, H., Heath, J. K. and Tickle, C (1995). Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80, 739-746.[Medline]

Crossley, P. H. and Martin, G. R (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.[Abstract]

Dell, K. R. and Williams, L. T (1992). A novel form of fibroblast growth factor receptor 2. Alternative splicing of the third immunoglobulin-like domain confers ligand binding specificity. J. Biol. Chem 267, 21225-21229.[Abstract/Free Full Text]

Deng, C. X., Wynshawboris, A., Shen, M. M., Daugherty, C., Ornitz, D. M. and Leder, P (1994). Murine Fgfr-1 is required for early postimplantation growth and axial organization. Genes Dev 8, 3045-3057.[Abstract/Free Full Text]

Fallon, J. F., Lopez, A., Ros, M. A., Savage, M. P., Olwin, B. B. and Simandl, B. K (1994). FGF-2: apical ectodermal ridge growth signal for chick limb development. Science 264, 104-107.[Abstract/Free Full Text]

Flanagan, J. G. and Leder, P (1990). The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell 63, 185-194.[Medline]

Ghattas, I. R., Sanes, J. R. and Majors, J. E (1991). The encephalomyocarditis virus internal ribosome entry site allows efficient coexpression of two genes from a recombinant provirus in cultured cells and in embryos. Mol. Cell. Biol 11, 5848-5859.[Abstract/Free Full Text]

Heikinheimo, M., Scandrett, J. M. and Wilson, D. B (1994). Localization of transcription factor GATA-4 to regions of the mouse embryo involved in cardiac development. Dev. Biol 164, 361-373.[Medline]

Heikinheimo, M., Lawshe, A., Shackleford, G. M., Wilson, D. B. and MacArthur, C. A (1994). Fgf-8 expression in the post-gastrulation mouse is localized to the developing face, limbs, and central nervous system. Mech. Dev 48, 129-138.[Medline]

Jabs, E. W., Li, X., Scott, A. F., Meyers, G., Chen, W., Eccles, M., Mao, J.-i., Charnes, L. R., Jackson, C. E. and Jaye, M (1994). Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2. Nature Genetics 8, 275-281.[Medline]

Johnson, D. E. and Williams, L. T (1993). Structural and functional diversity in the FGF receptor multigene family. Adv. Cancer Res 60, 1-41.[Medline]

Kouhara, H., Koga, M., Kasayama, S., Tanaka, A., Kishimoto, T. and Sato, B (1994). Transforming activity of a newly cloned androgen-induced growth factor. Oncogene 9, 455-462.[Medline]

Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. and Tabin, C (1994). Sonic Hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.[Medline]

MacArthur, C. A., Shankar, D. B. and Shackleford, G. M (1995). Fgf-8 , activated by proviral insertion, cooperates with the Wnt-1 transgene in murine mammary tumorigenesis. J. Virol 69, 2501-2507.[Abstract]

MacArthur, C. A., Lawshe, A., Shankar, D. B., Heikinheimo, M. and Shackleford, G. M (1995). FGF-8 isoforms differ in NIH3T3 cell transforming potential. Cell Growth Diff 6, 817-825.[Abstract]

Mansukhani, A., Dell'Era, P., Moscatelli, D., Kornbluth, S., Hanafusa, H. and Basilico, C (1992). Characterization of the murine BEK fibroblast growth factor (FGF) receptor: activation by three members of the FGF family and requirement for heparin. Proc. Natl. Acad. Sci.USA 89, 3305-3309.[Abstract/Free Full Text]

Miyamoto, M., Naruo, K.-I., Seko, C., Matsumoto, S., Kondo, T. and Kurokawa, T (1993). Molecular cloning of a novel cytokine cDNA encoding the ninth member of the fibroblast growth factor family, which has a unique secretion property. Mol. Cell. Biol 13, 4251-4259.[Abstract/Free Full Text]

Niswander, L., Tickle, C., Vogel, A., Booth, I. and Martin, G. R (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587.[Medline]

Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.[Medline]

Ohuchi, H., Yoshioka, H., Tanaka, A., Kawakami, Y., Nohno, T. and Noji, S (1994). Involvement of androgen-induced growth factor (Fgf-8) gene in mouse embryogenesis and morphogenesis. Biochem. Biophys. Res. Commun 204, 882-888.[Medline]

Ornitz, D. M., Yayon, A., Flanagan, J. G., Svahn, C. M., Levi, E. and Leder, P (1992). Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells. Mol. Cell. Biol 12, 240-247.[Abstract/Free Full Text]

Ornitz, D. M. and Leder, P (1992). Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3. J. Biol. Chem 267, 16305-16311.[Abstract/Free Full Text]

Orr-Urtreger, A., Givol, D., Yayon, A., Yarden, Y. and Lonai, P (1991). Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development 113, 1419-1434.[Abstract]

Orr-Urtreger, A., Bedford, M. T., Burakova, T., Arman, E., Zimmer, Y., Yayon, A., Givol, D. and Lonai, P (1993). Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Dev. Biol 158, 475-486.[Medline]

Peters, K., Werner, S., Chen, G. and Williams, L. T (1992). Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development 114, 233-243.[Abstract]

Peters, K., Ornitz, D. M., Werner, S. and Williams, L (1993). Uniqueexpression pattern of the FGF receptor 3 gene during mouse organogenesis. Dev. Biol 155, 423-440.[Medline]

Reardon, W., Winter, R. M., Rutland, P., L.J., P., Jones, B. M. and Malcolm, S (1994). Mutations in the fibroblast growth factor receptor 2 gene cause Crouzon syndrome. Nature Genetics 8, 98-103.[Medline]

Ron, D., Bottaro, D. P., Finch, P. W., Morris, D., Rubin, J. S. and Aaronson, S. A (1993). Expression of biologically active recombinant keratinocyte growth factor. J. Biol. Chem 268, 2984-2988.[Abstract/Free Full Text]

Sato, B., Kouhara, H., Koga, M., Kasayama, S., Saito, H., Sumitani, S., Hashimoto, K., Tanaka, A. and Matsumoto, K (1993). Androgen-induced growth factor and its receptor: demonstration of the androgen-induced autocrine loop in mouse mammary carcinoma cells. J. Steroid Biochem. Molec. Biol 47, 91-98.[Medline]

Shi, E., Kan, M., Xu, J., Wang, F., Hou, J. and McKeehan, W. L (1993). Control of fibroblast growth factor receptor kinase signal transduction by heterodimerization of combinatorial splice variants. Mol. Cell. Biol 13, 3907-3918.[Abstract/Free Full Text]

Stark, K. L., McMahon, J. A. and McMahon, A. P (1991). FGFR-4, a new member of the fibroblast growth factor receptor family, expressed in the definitive endoderm and skeletal muscle lineages of the mouse. Development 113, 641-651.[Abstract]

Tabin, C (1995). The initiation of the limb bud: growth factors, Hox genes, and retinoids. Cell 80, 671-674.[Medline]

Tanaka, A., Miyamoto, K., Minamino, N., Takeda, M., Sato, B., Matsuo, H. and Matsumoto, K (1992). Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc. Natl. Acad. Sci. USA 89, 8928-8932.[Abstract/Free Full Text]

Wang, J.-K., Gao, G. and Goldfarb, M (1994). Fibroblast growth factor receptors have different signaling and mitogenic potentials. Mol. Cell. Biol 14, 181-188.[Abstract/Free Full Text]

Werner, S., Duan, D. S., de Vries, C., Peters, K. G., Johnson, D. E. and Williams, D. T (1992). Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities. Mol. Cell. Biol 12, 82-88.[Abstract/Free Full Text]

Wilkie, A. O. M., Slaney, S. F., Oldridge, M., Poole, M. D., Ashworth, G. J., Hockley, A. D., Hayward, R. D., David, D. J., Pulleyn, L. J., Rutland, P., Malcolm, S., Winter, R. M. and Reardon, W (1995). Apert syndrome results from localized mutations of Fgfr2 and is allelic with Crouzon syndrome. Nature genetics 9, 165-172.[Medline]

Yamaguchi, T. P., Conlon, R. A. and Rossant, J (1992). Expression of the fibroblast growth factor receptor FGFR-1/ flg during gastrulation and segmentation in the mouse embryo. Dev. Biol 152, 75-88.[Medline]

Yamaguchi, T. P., Harpal, K., Henkemeyer, M. and Rossant, J (1994). Fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev 8, 3032-44.[Abstract/Free Full Text]

Yayon, A., Klagsbrun, M., Esko, J. D., Leder, P. and Ornitz, D. M (1991). Cell surface, heparin-like molecules are required for binding of basic fibroblast growth factor to its high affinity receptor. Cell 64, 841-848.[Medline]

This article has been cited by other articles:

M. Lagha, J. D. Kormish, D. Rocancourt, M. Manceau, J. A. Epstein, K. S. Zaret, F. Relaix, and M. E. Buckingham
Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program
Genes & Dev., July 1, 2008; 22(13): 1828 - 1837.
[Abstract] [Full Text] [PDF]

B. E. Jacques, M. E. Montcouquiol, E. M. Layman, M. Lewandoski, and M. W. Kelley
Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea
Development, August 15, 2007; 134(16): 3021 - 3029.
[Abstract] [Full Text] [PDF]

K. Sugiura, Y.-Q. Su, F. J. Diaz, S. A. Pangas, S. Sharma, K. Wigglesworth, M. J. O'Brien, M. M. Matzuk, S. Shimasaki, and J. J. Eppig
Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells
Development, July 15, 2007; 134(14): 2593 - 2603.
[Abstract] [Full Text] [PDF]

Q. Guo and J. Y. H. Li
Distinct functions of the major Fgf8 spliceform, Fgf8b, before and during mouse gastrulation
Development, June 15, 2007; 134(12): 2251 - 2260.
[Abstract] [Full Text] [PDF]

M. P. Valta, T. Hentunen, Q. Qu, E. M. Valve, A. Harjula, J. A. Seppanen, H. K. Vaananen, and P. L. Harkonen
Regulation of Osteoblast Differentiation: A Novel Function for Fibroblast Growth Factor 8
Endocrinology, May 1, 2006; 147(5): 2171 - 2182.
[Abstract] [Full Text] [PDF]

R. B. Fletcher, J. C. Baker, and R. M. Harland
FGF8 spliceforms mediate early mesoderm and posterior neural tissue formation in Xenopus
Development, May 1, 2006; 133(9): 1703 - 1714.
[Abstract] [Full Text] [PDF]

S. K. Olsen, J. Y.H. Li, C. Bromleigh, A. V. Eliseenkova, O. A. Ibrahimi, Z. Lao, F. Zhang, R. J. Linhardt, A. L. Joyner, and M. Mohammadi
Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
Genes & Dev., January 15, 2006; 20(2): 185 - 198.
[Abstract] [Full Text] [PDF]

J Buratini Jr, A B Teixeira, I B Costa, V F Glapinski, M G L Pinto, I C Giometti, C M Barros, M Cao, E S Nicola, and C A Price
Expression of fibroblast growth factor-8 and regulation of cognate receptors, fibroblast growth factor receptor-3c and -4, in bovine antral follicles
Reproduction, September 1, 2005; 130(3): 343 - 350.
[Abstract] [Full Text] [PDF]

N. Shimada, T. Ishii, T. Imada, K. Takaba, Y. Sasaki, K. Maruyama-Takahashi, Y. Maekawa-Tokuda, H. Kusaka, S. Akinaga, A. Tanaka, et al.
A Neutralizing Anti-Fibroblast Growth Factor 8 Monoclonal Antibody Shows Potent Antitumor Activity against Androgen-Dependent Mouse Mammary Tumors In vivo
Clin. Cancer Res., May 15, 2005; 11(10): 3897 - 3904.
[Abstract] [Full Text] [PDF]

X. Zeng, J. Cai, J. Chen, Y. Luo, Z.-B. You, E. Fotter, Y. Wang, B. Harvey, T. Miura, C. Backman, et al.
Dopaminergic Differentiation of Human Embryonic Stem Cells
Stem Cells, November 1, 2004; 22(6): 925 - 940.
[Abstract] [Full Text] [PDF]

T. Sato and H. Nakamura
The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway
Development, September 1, 2004; 131(17): 4275 - 4285.
[Abstract] [Full Text] [PDF]

N. Kessaris, F. Jamen, L. L. Rubin, and W. D. Richardson
Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors
Development, March 15, 2004; 131(6): 1289 - 1298.
[Abstract] [Full Text] [PDF]

O. A. Ibrahimi, F. Zhang, A. V. Eliseenkova, R. J. Linhardt, and M. Mohammadi
Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke craniosynostosis syndromes through enhancement of FGF binding affinity
Hum. Mol. Genet., January 1, 2004; 13(1): 69 - 78.
[Abstract] [Full Text] [PDF]

T. L. Macatee, B. P. Hammond, B. R. Arenkiel, L. Francis, D. U. Frank, and A. M. Moon
Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development
Development, December 22, 2003; 130(25): 6361 - 6374.
[Abstract] [Full Text] [PDF]

M. Borgenstrom, M. Jalkanen, and M. Salmivirta
Sulfated Derivatives of Escherichia coli K5 Polysaccharides as Modulators of Fibroblast Growth Factor Signaling
J. Biol. Chem., December 12, 2003; 278(50): 49882 - 49889.
[Abstract] [Full Text] [PDF]

B. L. Allen and A. C. Rapraeger
Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly
J. Cell Biol., November 10, 2003; 163(3): 637 - 648.
[Abstract] [Full Text] [PDF]

S. Scholpp, C. Lohs, and M. Brand
Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon
Development, October 15, 2003; 130(20): 4881 - 4893.
[Abstract] [Full Text] [PDF]

S. K. Olsen, M. Garbi, N. Zampieri, A. V. Eliseenkova, D. M. Ornitz, M. Goldfarb, and M. Mohammadi
Fibroblast Growth Factor (FGF) Homologous Factors Share Structural but Not Functional Homology with FGFs
J. Biol. Chem., September 5, 2003; 278(36): 34226 - 34236.
[Abstract] [Full Text] [PDF]

D. Bachiller, J. Klingensmith, N. Shneyder, U. Tran, R. Anderson, J. Rossant, and E. M. De Robertis
The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome
Development, August 1, 2003; 130(15): 3567 - 3578.
[Abstract] [Full Text] [PDF]

A. Fomenkov, Y.-P. Huang, O. Topaloglu, A. Brechman, M. Osada, T. Fomenkova, E. Yuriditsky, B. Trink, D. Sidransky, and E. Ratovitski
p63{alpha} Mutations Lead to Aberrant Splicing of Keratinocyte Growth Factor Receptor in the Hay-Wells Syndrome
J. Biol. Chem., June 20, 2003; 278(26): 23906 - 23914.
[Abstract] [Full Text] [PDF]

J. L. Kirby, L. Yang, J. C. Labus, and B. T. Hinton
Characterization of Fibroblast Growth Factor Receptors Expressed in Principal Cells in the Initial Segment of the Rat Epididymis
Biol Reprod, June 1, 2003; 68(6): 2314 - 2321.
[Abstract] [Full Text] [PDF]

S. Agarwala and C. W. Ragsdale
A role for midbrain arcs in nucleogenesis
Development, March 14, 2003; 129(24): 5779 - 5788.
[Abstract] [Full Text] [PDF]

E. E. Storm, J. L. R. Rubenstein, and G. R. Martin
Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain
PNAS, February 18, 2003; 100(4): 1757 - 1762.
[Abstract] [Full Text] [PDF]

Z. Song, X. Wu, W. C. Powell, R. D. Cardiff, M. B. Cohen, R. T. Tin, R. J. Matusik, G. J. Miller, and P. Roy-Burman
Fibroblast Growth Factor 8 Isoform b Overexpression in Prostate Epithelium: A New Mouse Model for Prostatic Intraepithelial Neoplasia
Cancer Res., September 1, 2002; 62(17): 5096 - 5105.
[Abstract] [Full Text] [PDF]

B.-M. Loo and M. Salmivirta
Heparin/Heparan Sulfate Domains in Binding and Signaling of Fibroblast Growth Factor 8b
J. Biol. Chem., August 30, 2002; 277(36): 32616 - 32623.
[Abstract] [Full Text] [PDF]

D. U. Frank, L. K. Fotheringham, J. A. Brewer, L. J. Muglia, M. Tristani-Firouzi, M. R. Capecchi, and A. M. Moon
An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome
Development, January 10, 2002; 129(19): 4591 - 4603.
[Abstract] [Full Text] [PDF]

T. Sato, I. Araki, and H. Nakamura
Inductive signal and tissue responsiveness defining the tectum and the cerebellum
Development, July 1, 2001; 128(13): 2461 - 2469.
[Abstract] [Full Text] [PDF]

J. K. Ruohola, T. P. Viitanen, E. M. Valve, J. A. Seppänen, N. T. Loponen, J. J. Keskitalo, P. T. Lakkakorpi, and P. L. Härkönen
Enhanced Invasion and Tumor Growth of Fibroblast Growth Factor 8b-overexpressing MCF-7 Human Breast Cancer Cells
Cancer Res., May 1, 2001; 61(10): 4229 - 4237.
[Abstract] [Full Text]

Z. Song, W. C. Powell, N. Kasahara, A. van Bokhoven, G. J. Miller, and P. Roy-Burman
The Effect of Fibroblast Growth Factor 8, Isoform b, on the Biology of Prostate Carcinoma Cells and Their Interaction with Stromal Cells
Cancer Res., December 1, 2000; 60(23): 6730 - 6736.
[Abstract] [Full Text]

B. Thomas, J. Liu, J. Rubenstein, and P. Sharpe
Independent regulation of Dlx2 expression in the epithelium and mesenchyme of the first branchial arch
Development, January 1, 2000; 127(2): 217 - 224.
[Abstract] [PDF]

F Reifers, E. Walsh, S Leger, D. Stainier, and M Brand
Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar)
Development, January 1, 2000; 127(2): 225 - 235.
[Abstract] [PDF]

A. Chellaiah, W. Yuan, M. Chellaiah, and D. M. Ornitz
Mapping Ligand Binding Domains in Chimeric Fibroblast Growth Factor Receptor Molecules. MULTIPLE REGIONS DETERMINE LIGAND BINDING SPECIFICITY
J. Biol. Chem., December 3, 1999; 274(49): 34785 - 34794.
[Abstract] [Full Text] [PDF]

V. M. Byrd, D. W. Ballard, G. G. Miller, and J. W. Thomas
Fibroblast Growth Factor-1 (FGF-1) Enhances IL-2 Production and Nuclear Translocation of NF-{kappa}B in FGF Receptor-Bearing Jurkat T Cells
J. Immunol., May 15, 1999; 162(10): 5853 - 5859.
[Abstract] [Full Text] [PDF]

J. Gemel, C. Jacobsen, and C. A. MacArthur
Fibroblast Growth Factor-8 Expression Is Regulated by Intronic Engrailed and Pbx1-binding Sites
J. Biol. Chem., February 26, 1999; 274(9): 6020 - 6026.
[Abstract] [Full Text] [PDF]

A Liu, K Losos, and A. Joyner
FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate
Development, January 11, 1999; 126(21): 4827 - 4838.
[Abstract] [PDF]

S Martinez, P. Crossley, I Cobos, J. Rubenstein, and G. Martin
FGF8 induces formation of an ectopic isthmic organizer and isthmocerebellar development via a repressive effect on Otx2 expression
Development, January 3, 1999; 126(6): 1189 - 1200.
[Abstract] [PDF]

H Shamim, R Mahmood, C Logan, P Doherty, A Lumsden, and I Mason
Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain
Development, January 2, 1999; 126(5): 945 - 959.
[Abstract] [PDF]

I Munoz-Sanjuan, B. Simandl, J. Fallon, and J Nathans
Expression of chicken fibroblast growth factor homologous factor (FHF)-1 and of differentially spliced isoforms of FHF-2 during development and involvement of FHF-2 in chicken limb development
Development, January 1, 1999; 126(2): 409 - 421.
[Abstract] [PDF]

F. Lovicu and P. Overbeek
Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice
Development, January 9, 1998; 125(17): 3365 - 3377.
[Abstract] [PDF]

F Reifers, H Bohli, E. Walsh, P. Crossley, D. Stainier, and M Brand
Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis
Development, January 7, 1998; 125(13): 2381 - 2395.
[Abstract] [PDF]

J Ericson, S Norlin, T. Jessell, and T Edlund
Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary
Development, January 3, 1998; 125(6): 1005 - 1015.
[Abstract] [PDF]

X Xu, M Weinstein, C Li, M Naski, R. Cohen, D. Ornitz, P Leder, and C Deng
Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
Development, January 2, 1998; 125(4): 753 - 765.
[Abstract] [PDF]

A. G. Blunt, A. Lawshe, M. L. Cunningham, M. L. Seto, D. M. Ornitz, and C. A. MacArthur
Overlapping Expression and Redundant Activation of Mesenchymal Fibroblast Growth Factor (FGF) Receptors by Alternatively Spliced FGF-8 Ligands
J. Biol. Chem., February 7, 1997; 272(6): 3733 - 3738.
[Abstract] [Full Text] [PDF]

M Furthauer, C Thisse, and B Thisse
A role for FGF-8 in the dorsoventral patterning of the zebrafish gastrula
Development, January 11, 1997; 124(21): 4253 - 4264.
[Abstract] [PDF]

H Ohuchi, T Nakagawa, A Yamamoto, A Araga, T Ohata, Y Ishimaru, H Yoshioka, T Kuwana, T Nohno, M Yamasaki, et al.
The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor
Development, January 6, 1997; 124(11): 2235 - 2244.
[Abstract] [PDF]

S. Lee, P. Danielian, B Fritzsch, and A. McMahon
Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain
Development, January 3, 1997; 124(5): 959 - 969.
[Abstract] [PDF]

D. M. Ornitz, J. Xu, J. S. Colvin, D. G. McEwen, C. A. MacArthur, F. Coulier, G. Gao, and M. Goldfarb
Receptor Specificity of the Fibroblast Growth Factor Family
J. Biol. Chem., June 21, 1996; 271(25): 15292 - 15297.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by MacArthur, C. A.

Articles by Ornitz, D. M.

Search for Related Content

PubMed

PubMed Citation

Articles by MacArthur, C. A.

Articles by Ornitz, D. M.

				B. E. Jacques, M. E. Montcouquiol, E. M. Layman, M. Lewandoski, and M. W. Kelley Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea Development, August 15, 2007; 134(16): 3021 - 3029. [Abstract] [Full Text] [PDF]

				K. Sugiura, Y.-Q. Su, F. J. Diaz, S. A. Pangas, S. Sharma, K. Wigglesworth, M. J. O'Brien, M. M. Matzuk, S. Shimasaki, and J. J. Eppig Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells Development, July 15, 2007; 134(14): 2593 - 2603. [Abstract] [Full Text] [PDF]

				Q. Guo and J. Y. H. Li Distinct functions of the major Fgf8 spliceform, Fgf8b, before and during mouse gastrulation Development, June 15, 2007; 134(12): 2251 - 2260. [Abstract] [Full Text] [PDF]

				M. P. Valta, T. Hentunen, Q. Qu, E. M. Valve, A. Harjula, J. A. Seppanen, H. K. Vaananen, and P. L. Harkonen Regulation of Osteoblast Differentiation: A Novel Function for Fibroblast Growth Factor 8 Endocrinology, May 1, 2006; 147(5): 2171 - 2182. [Abstract] [Full Text] [PDF]

				R. B. Fletcher, J. C. Baker, and R. M. Harland FGF8 spliceforms mediate early mesoderm and posterior neural tissue formation in Xenopus Development, May 1, 2006; 133(9): 1703 - 1714. [Abstract] [Full Text] [PDF]

				S. K. Olsen, J. Y.H. Li, C. Bromleigh, A. V. Eliseenkova, O. A. Ibrahimi, Z. Lao, F. Zhang, R. J. Linhardt, A. L. Joyner, and M. Mohammadi Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain Genes & Dev., January 15, 2006; 20(2): 185 - 198. [Abstract] [Full Text] [PDF]

				J Buratini Jr, A B Teixeira, I B Costa, V F Glapinski, M G L Pinto, I C Giometti, C M Barros, M Cao, E S Nicola, and C A Price Expression of fibroblast growth factor-8 and regulation of cognate receptors, fibroblast growth factor receptor-3c and -4, in bovine antral follicles Reproduction, September 1, 2005; 130(3): 343 - 350. [Abstract] [Full Text] [PDF]

				N. Shimada, T. Ishii, T. Imada, K. Takaba, Y. Sasaki, K. Maruyama-Takahashi, Y. Maekawa-Tokuda, H. Kusaka, S. Akinaga, A. Tanaka, et al. A Neutralizing Anti-Fibroblast Growth Factor 8 Monoclonal Antibody Shows Potent Antitumor Activity against Androgen-Dependent Mouse Mammary Tumors In vivo Clin. Cancer Res., May 15, 2005; 11(10): 3897 - 3904. [Abstract] [Full Text] [PDF]

				X. Zeng, J. Cai, J. Chen, Y. Luo, Z.-B. You, E. Fotter, Y. Wang, B. Harvey, T. Miura, C. Backman, et al. Dopaminergic Differentiation of Human Embryonic Stem Cells Stem Cells, November 1, 2004; 22(6): 925 - 940. [Abstract] [Full Text] [PDF]

				T. Sato and H. Nakamura The Fgf8 signal causes cerebellar differentiation by activating the Ras-ERK signaling pathway Development, September 1, 2004; 131(17): 4275 - 4285. [Abstract] [Full Text] [PDF]

				N. Kessaris, F. Jamen, L. L. Rubin, and W. D. Richardson Cooperation between sonic hedgehog and fibroblast growth factor/MAPK signalling pathways in neocortical precursors Development, March 15, 2004; 131(6): 1289 - 1298. [Abstract] [Full Text] [PDF]

				O. A. Ibrahimi, F. Zhang, A. V. Eliseenkova, R. J. Linhardt, and M. Mohammadi Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke craniosynostosis syndromes through enhancement of FGF binding affinity Hum. Mol. Genet., January 1, 2004; 13(1): 69 - 78. [Abstract] [Full Text] [PDF]

				T. L. Macatee, B. P. Hammond, B. R. Arenkiel, L. Francis, D. U. Frank, and A. M. Moon Ablation of specific expression domains reveals discrete functions of ectoderm- and endoderm-derived FGF8 during cardiovascular and pharyngeal development Development, December 22, 2003; 130(25): 6361 - 6374. [Abstract] [Full Text] [PDF]

				M. Borgenstrom, M. Jalkanen, and M. Salmivirta Sulfated Derivatives of Escherichia coli K5 Polysaccharides as Modulators of Fibroblast Growth Factor Signaling J. Biol. Chem., December 12, 2003; 278(50): 49882 - 49889. [Abstract] [Full Text] [PDF]

				B. L. Allen and A. C. Rapraeger Spatial and temporal expression of heparan sulfate in mouse development regulates FGF and FGF receptor assembly J. Cell Biol., November 10, 2003; 163(3): 637 - 648. [Abstract] [Full Text] [PDF]

				S. Scholpp, C. Lohs, and M. Brand Engrailed and Fgf8 act synergistically to maintain the boundary between diencephalon and mesencephalon Development, October 15, 2003; 130(20): 4881 - 4893. [Abstract] [Full Text] [PDF]

				S. K. Olsen, M. Garbi, N. Zampieri, A. V. Eliseenkova, D. M. Ornitz, M. Goldfarb, and M. Mohammadi Fibroblast Growth Factor (FGF) Homologous Factors Share Structural but Not Functional Homology with FGFs J. Biol. Chem., September 5, 2003; 278(36): 34226 - 34236. [Abstract] [Full Text] [PDF]

				D. Bachiller, J. Klingensmith, N. Shneyder, U. Tran, R. Anderson, J. Rossant, and E. M. De Robertis The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome Development, August 1, 2003; 130(15): 3567 - 3578. [Abstract] [Full Text] [PDF]

				A. Fomenkov, Y.-P. Huang, O. Topaloglu, A. Brechman, M. Osada, T. Fomenkova, E. Yuriditsky, B. Trink, D. Sidransky, and E. Ratovitski p63{alpha} Mutations Lead to Aberrant Splicing of Keratinocyte Growth Factor Receptor in the Hay-Wells Syndrome J. Biol. Chem., June 20, 2003; 278(26): 23906 - 23914. [Abstract] [Full Text] [PDF]

				J. L. Kirby, L. Yang, J. C. Labus, and B. T. Hinton Characterization of Fibroblast Growth Factor Receptors Expressed in Principal Cells in the Initial Segment of the Rat Epididymis Biol Reprod, June 1, 2003; 68(6): 2314 - 2321. [Abstract] [Full Text] [PDF]

				S. Agarwala and C. W. Ragsdale A role for midbrain arcs in nucleogenesis Development, March 14, 2003; 129(24): 5779 - 5788. [Abstract] [Full Text] [PDF]

				E. E. Storm, J. L. R. Rubenstein, and G. R. Martin Dosage of Fgf8 determines whether cell survival is positively or negatively regulated in the developing forebrain PNAS, February 18, 2003; 100(4): 1757 - 1762. [Abstract] [Full Text] [PDF]

				Z. Song, X. Wu, W. C. Powell, R. D. Cardiff, M. B. Cohen, R. T. Tin, R. J. Matusik, G. J. Miller, and P. Roy-Burman Fibroblast Growth Factor 8 Isoform b Overexpression in Prostate Epithelium: A New Mouse Model for Prostatic Intraepithelial Neoplasia Cancer Res., September 1, 2002; 62(17): 5096 - 5105. [Abstract] [Full Text] [PDF]

				B.-M. Loo and M. Salmivirta Heparin/Heparan Sulfate Domains in Binding and Signaling of Fibroblast Growth Factor 8b J. Biol. Chem., August 30, 2002; 277(36): 32616 - 32623. [Abstract] [Full Text] [PDF]

				D. U. Frank, L. K. Fotheringham, J. A. Brewer, L. J. Muglia, M. Tristani-Firouzi, M. R. Capecchi, and A. M. Moon An Fgf8 mouse mutant phenocopies human 22q11 deletion syndrome Development, January 10, 2002; 129(19): 4591 - 4603. [Abstract] [Full Text] [PDF]

				T. Sato, I. Araki, and H. Nakamura Inductive signal and tissue responsiveness defining the tectum and the cerebellum Development, July 1, 2001; 128(13): 2461 - 2469. [Abstract] [Full Text] [PDF]

				J. K. Ruohola, T. P. Viitanen, E. M. Valve, J. A. Seppänen, N. T. Loponen, J. J. Keskitalo, P. T. Lakkakorpi, and P. L. Härkönen Enhanced Invasion and Tumor Growth of Fibroblast Growth Factor 8b-overexpressing MCF-7 Human Breast Cancer Cells Cancer Res., May 1, 2001; 61(10): 4229 - 4237. [Abstract] [Full Text]

				Z. Song, W. C. Powell, N. Kasahara, A. van Bokhoven, G. J. Miller, and P. Roy-Burman The Effect of Fibroblast Growth Factor 8, Isoform b, on the Biology of Prostate Carcinoma Cells and Their Interaction with Stromal Cells Cancer Res., December 1, 2000; 60(23): 6730 - 6736. [Abstract] [Full Text]

				B. Thomas, J. Liu, J. Rubenstein, and P. Sharpe Independent regulation of Dlx2 expression in the epithelium and mesenchyme of the first branchial arch Development, January 1, 2000; 127(2): 217 - 224. [Abstract] [PDF]

				F Reifers, E. Walsh, S Leger, D. Stainier, and M Brand Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar) Development, January 1, 2000; 127(2): 225 - 235. [Abstract] [PDF]