FGF suppresses apoptosis and induces differentiation of fibre cells in the mouse lens

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Chow, R. L.
	Articles by Lang, R. A.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Chow, R. L.
	Articles by Lang, R. A.


Social Bookmarking

	What's this?

Amaya, E., Musci, T. J. and Kirschner, M. W (1991). Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.[Medline]

Beebe, D. C., Feagans, D. E. and Jebens, H. A (1980). Lentropin: a factor in vitreous humor which promotes lens fiber cell differentiation. Proc. Natl. Acad. Sci. USA 77, 490-493.[Abstract/Free Full Text]

Beebe, D. C., Silver, M. H., Belcher, K. S., Van Wyk, J. J., Svoboda, M. E. and Zelenka, P. S (1987). Lentropin, a protein that controls lens fiber formation, is related functionally and immunologically to the insulin-like growth factors. Proc. Natl. Acad. Sci. USA 84, 2327-2330.[Abstract/Free Full Text]

Bernard, O., Li, M. and Reid, H (1991). Expression of two different forms of fibroblast growth factor receptor 1 in different mouse tissues and cell lines. Proc. Natl. Acad. Sci. USA 88, 7625-7629.[Abstract/Free Full Text]

Breitman, M. L., Bryce, D. M., Giddens, E., Clapoff, S., Goring, D., Tsui, L. C., Klintworth, G. K. and Bernstein, A (1989). Analysis of lens cell fate and eye morphogenesis in transgenic mice ablated for cells of the lens lineage. Development 106, 457-463.[Abstract]

Cecchini, M. G., Dominguez, M. G., Mocci, S., Wetterwald, A., Felix, R., Fleisch, H., Chisholm, O., Hofstetter, W., Pollard, J. and Stanley, E. R (1994). Role of colony stimulating factor-1 in the establishment and regulation of tissue macrophages during postnatal development of the mouse. Development 120, 1357-1372.[Abstract]

Chamberlain, C. G., McAvoy, J. W. and Richardson, N. A (1991). The effects of insulin and basic fibroblast growth factor on fibre differentiation in rat lens epithelial explants. Growth Factors 4, 183-188.[Medline]

Chapelinsky, A. B., King, C. R., Zelenka, P. S. and Piatigorsky, J (1985). Lens specified expression of the chloramphenicol acetyltransferase gene promoted by 5flanking sequences of the murine A-crystalline gene in explanted chicken lens epithelia. Proc. Natl. Acad. Sci. USA 82, 2334-2338.[Abstract/Free Full Text]

Cobb, M., Boulton, T. and Robbins, D (1991). Extracellular signal-related kinases: ERKs in progress. Cell Regulation 2, 965-978.[Medline]

Coulombre, J. L. and Coulombre, A. J (1963). Lens development: fibre elongation and lens orientation. Science 142, 1489-1490.[Abstract/Free Full Text]

de Iongh, R. and McAvoy, J. W (1992). Distribution of acidic and basic fibroblast growth factors (FGF) in the foetal rat eye: implications for lens development. Growth Factors 6, 159-177.[Medline]

Desci, A., Peiffer, R. L., Qiu, T., Lee, D. C., Friday, J. T. and Bautch, V. L (1994). Lens expression of TGF alpha in transgenic mice produces two distinct eye pathologies in the absence of tumors. Oncogene 9, 1965-1975.[Medline]

Egwuagu, C. E., Sztein, J., Chan, C. C., Reid, W., Mahdi, R., Nussenblatt, R. B. and Chepelinsky, A. B (1994). Ectopic expression of gamma interferon in the eyes of transgenic mice induces ocular pathology and MHC class II gene expression. Investigative Ophthalmology & Visual Science 35, 332-341.[Abstract/Free Full Text]

Feldman, B., Poueymirou, W., Papaioannou, V. E., DeChiara, T. M. and Goldfarb, M (1995). Requirement of FGF-4 for postimplantation mouse development. Science 267, 246-249.[Abstract/Free Full Text]

Gavrieli, Y., Sherman, Y. and Ben-Sasson, S. A (1992). Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell. Biol 119, 493-501.[Abstract/Free Full Text]

Gonda, T. J., Sheiness, D. K. and Bishop, J. M (1982). Transcripts from the cellular homologues of retroviral oncogenes: distribution among chicken tissues. Mol. Cell. Biol 2, 617-624.[Abstract/Free Full Text]

Hebert, J. M., Rosenquist, T., Gotz, J. and Martin, G. R (1994). FGF5 as a regulator of the hair growth cycle: Evidence from spontaneous and targeted mutations. Cell 78, 1017-1025.[Medline]

Hogan, B., Costantini, F. and Lacy, E (1986). Manipulating the Mouse Embryo: A Laboratory Manual._Fb_Ishizaki, Y., Voyvodic, J. T., Burne, J. F. and Raff, M. C. (1993). Control of lens epithelial cell survival. J. Cell. Biol 121, 899-908.[Abstract/Free Full Text]

Lang, R. A., Lustig, M., Francois, F., Sellinger, M. and Plesken, H (1994). Apoptosis during macrophage-dependent tissue remodelling. Development 120, 3395-3403.[Abstract]

Li, Y., Basilico, C. and Mansukhani, A (1994). Cell transformation by fibroblast growth factors can be suppressed by truncated fibroblast growth factor receptors. Mol. Cell. Biol 14, 7660-7669.[Abstract/Free Full Text]

Lieschke, G. J., Stanley, E., Grail, D., Hodgson, G., Sinickas, V., Gall, J. A., Sinclair, R. A. and Dunn, A. R (1994). Mice lacking both macrophage-and granulocyte-macrophage colony-stimulating factor have macrophages and coexistent osteopetrosis and severe lung disease. Blood 84, 27-35.[Abstract/Free Full Text]

Mann, G. B., Fowler, K. J., Gabriel, A., Nice, E. C., Williams, R. L. and Dunn, A. R (1993). Mice with a null mutation of the TGF alpha gene have abnormal skin architecture, wavy hair, and curly whiskers and often develop corneal inflammation. Cell 73, 249-261.[Medline]

Mansour, S. L., Goddard, J. M. and Capecchi, M. R (1993). Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development 117, 13-28.[Abstract/Free Full Text]

McAvoy, J. and Chamberlain, C (1989). Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development 107, 221-228.[Abstract]

McAvoy, J. W (1978). Cell division, cell elongation and distribution of alpha-, beta-and gamma-crystallins in the rat lens. J. Embryol. Exp. Morp 44, 149-165.[Medline]

McAvoy, J. W. and Chamberlain, C. G (1989). Fibroblast growth factor (FGF) induces different responses in lens epithelial cells depending on its concentration. Development 107, 221-228.

McAvoy, J. W., Chamberlain, C. G., de Iongh, R. U., Richardson, N. A. and Lovicu, F. J (1991). The role of fibroblast growth factor in eye lens development. Ann. New York Academy Sci 638, 256-74.[Medline]

Metcalf, D (1985). The granulocyte-macrophage colony-stimulating factors. Science 229, 16-22.[Abstract/Free Full Text]

Orr-Urtreger, A., Givol, G., Yayon, A., Yarden, Y. and Lonai, P (1991). Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development 113, 1419-1434.[Abstract]

Peters, K., Werner, S., Liao, X., Wert, S., Whitsett, J. and Williams, L (1994). Targeted expression of a dominant negative FGF receptor blocks branching morphogenesis and epithelial differentiation of the mouse lung. EMBO J 13, 3296-3301.[Medline]

Piatigorsky, J., Webster H de, F. and Wollberg, M (1972). Cell elongation in the cultured embryonic chick lens epithelium with and without protein synthesis. Involvement of microtubules. J. Cell Biol 55, 82-92.[Abstract/Free Full Text]

Raff, M. C (1992). Social controls on cell survival and cell death. Science 256, 397-400.

Robinson, M. L., Overbeek, P. A., Verran, D. J., Grizzle, W. E., Stockard, C. R., Friesel, R., Maciag, T. and Thompson, J. A (1995). Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice. Development 121, 505-514.[Abstract]

Roghani, M., Mansukhani, A., Dell'Era, P., Bellosta, P., Basilico, C. and Moscatelli, D (1994). Heparin increases the affinity of basic fibroblast growth factor for its receptor but is not required for binding. J. Biol. Chem 269, 3976-3984.[Abstract/Free Full Text]

Ruoslahti, E. and Reed, J. C (1994). Anchorage dependence, integrins, and apoptosis. Cell 77, 477-478.[Medline]

Sanwal, M., Muel, A. S., Chaudun, E., Courtois, Y. and Counis, M. F (1986). Chromatin condensation and terminal differentiation process in embryonic chicken lens in vivo and in vitro. Exp. Cell Research 167, 429-439.[Medline]

Shiels, A., Griffin, C. S. and Muggleton-Harris, A. L (1991). Immunochemical comparison of the major intrinsic protein of eye-lens fiber cell membranes in mice with hereditary cataracts. Biochimica et Biophysica Acta 1097, 318-324.[Medline]

Taketo, M., Schroeder, A. C., Mobraaten, L. E., Gunning, K. B., Hanten, G., Fox, R. R., Roderick, T. H., Stewart, C. L., Lilly, F., Hansen, C. T. and Overbeek, P. A (1991). An inbred mouse strain preferable for transgenic analyses. Proc. Natl. Acad. Sci. USA 88, 2065-2069.[Abstract/Free Full Text]

Treton, J. A., Jacquemin, E., Courtois, Y. and Jeanny, J. C (1991). Differential localization by in situ hybridization of specific crystallin transcripts during mouse lens development. Differentiation 47, 143-147.[Medline]

Ueno, H., Gunn, M., Dell, K., Tseng, A. and Williams, L (1992). A truncated form of fibroblast growth factor receptor 1 inhibits signal transduction by multiple types of fibroblast growth factor receptor. J. Biol. Chem 267, 1470-1476.[Abstract/Free Full Text]

Van Leen, R. W., Breuer, M. L., Lubsen, N. H. and Schoenmakers, J. G. G (1987). Developmental expression of crystallin genes: In situ hybridization reveals a differential localization of specific mRNAs. Dev. Biol 123, 338-345.[Medline]

Werner, S., Weinberg, W., Liao, X., Peters, K. G., Blessing, M., Yuspa, S. H., Weiner, R. L. and Williams, L. T (1993). Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation. EMBO J 12, 2635-2643.[Medline]

Williams, G. T., Smith, C. A., Spooncer, E., Dexter, T. M. and Taylor, D. R (1990). Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature 343, 76-79.[Medline]

Wyllie, A. H., Kerr, J. F. R. and Currie, A. R (1980). Cell death: The significance of apoptosis. Int. Rev. Cytol 68, 251-305.[Medline]

Yamaguchi, T. P., Hapal, K., Henkemeyer, M. and Rossant, J (1994). fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation. Genes Dev 8, 3032-3044.[Abstract/Free Full Text]

Yamamoto, Y (1976). Growth of lens and ocular environment: role of neural retina in the growth of mouse lens as revealed by an implantation experiment. Development, Growth and Differentiation 18, 273-278.

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

N. Golestaneh, J. Fan, R. N. Fariss, W.-K. Lo, P. S. Zelenka, and A. B. Chepelinsky
Lens Major Intrinsic Protein (MIP)/Aquaporin 0 Expression in Rat Lens Epithelia Explants Requires Fibroblast Growth Factor-induced ERK and JNK Signaling
J. Biol. Chem., July 23, 2004; 279(30): 31813 - 31822.
[Abstract] [Full Text] [PDF]

R. Simon and T. Lufkin
Postnatal Lethality in Mice Lacking the Sax2 Homeobox Gene Homologous to Drosophila S59/slouch: Evidence for Positive and Negative Autoregulation
Mol. Cell. Biol., December 15, 2003; 23(24): 9046 - 9060.
[Abstract] [Full Text] [PDF]

V. Traverso, N. Kinkl, L. Grimm, J. Sahel, and D. Hicks
Basic Fibroblast and Epidermal Growth Factors Stimulate Survival in Adult Porcine Photoreceptor Cell Cultures
Invest. Ophthalmol. Vis. Sci., October 1, 2003; 44(10): 4550 - 4558.
[Abstract] [Full Text] [PDF]

T. L. Belecky-Adams, R. Adler, and D. C. Beebe
Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation
Development, March 10, 2003; 129(16): 3795 - 3802.
[Abstract] [Full Text] [PDF]

J.-X. Huang, M. Feldmeier, Y.-B. Shui, and D. C. Beebe
Evaluation of Fibroblast Growth Factor Signaling during Lens Fiber Cell Differentiation
Invest. Ophthalmol. Vis. Sci., February 1, 2003; 44(2): 680 - 690.
[Abstract] [Full Text] [PDF]

S. C. Faber, M. L. Robinson, H. P. Makarenkova, and R. A. Lang
Bmp signaling is required for development of primary lens fiber cells
Development, August 1, 2002; 129(15): 3727 - 3737.
[Abstract] [Full Text] [PDF]

F. J. Lovicu and J. W. McAvoy
FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling
Development, December 15, 2001; 128(24): 5075 - 5084.
[Abstract] [Full Text] [PDF]

S. C. Faber, P. Dimanlig, H. P. Makarenkova, S. Shirke, K. Ko, and R. A. Lang
Fgf receptor signaling plays a role in lens induction
Development, November 15, 2001; 128(22): 4425 - 4438.
[Abstract] [Full Text] [PDF]

A.-C. N. Le and L. S. Musil
A novel role for FGF and extracellular signal-regulated kinase in gap junction-mediated intercellular communication in the lens
J. Cell Biol., July 9, 2001; 154(1): 197 - 216.
[Abstract] [Full Text] [PDF]

I. M. Wormstone, K. Del Rio–Tsonis, G. McMahon, S. Tamiya, P. D. Davies, J. M. Marcantonio, and G. Duncan
FGF: An Autocrine Regulator of Human Lens Cell Growth Independent of Added Stimuli
Invest. Ophthalmol. Vis. Sci., May 1, 2001; 42(6): 1305 - 1311.
[Abstract] [Full Text]

J. Lemonnier, E. Hay, P. Delannoy, O. Fromigue, A. Lomri, D. Modrowski, and P. J. Marie
Increased Osteoblast Apoptosis in Apert Craniosynostosis : Role of Protein Kinase C and Interleukin-1
Am. J. Pathol., May 1, 2001; 158(5): 1833 - 1842.
[Abstract] [Full Text] [PDF]

X. Gong, X. Wang, J. Han, I. Niesman, Q. Huang, and J. Horwitz
Development of Cataractous Macrophthalmia in Mice Expressing an Active MEK1 in the Lens
Invest. Ophthalmol. Vis. Sci., March 1, 2001; 42(3): 539 - 548.
[Abstract] [Full Text]

V Govindarajan and P. Overbeek
Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation
Development, January 5, 2001; 128(9): 1617 - 1627.
[Abstract] [PDF]

Y. Ueda, C. G. Chamberlain, K. Satoh, and J. W. McAvoy
Inhibition of FGF-Induced {alpha}A-Crystallin Promoter Activity in Lens Epithelial Explants by TGF{beta}
Invest. Ophthalmol. Vis. Sci., June 1, 2000; 41(7): 1833 - 1839.
[Abstract] [Full Text]

A. Blixt, M. Mahlapuu, M. Aitola, M. Pelto-Huikko, S. Enerbäck, and P. Carlsson
A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle
Genes & Dev., January 15, 2000; 14(2): 245 - 254.
[Abstract] [Full Text]

R. A. Lang
Which Factors Stimulate Lens Fiber Cell Differentiation In Vivo?
Invest. Ophthalmol. Vis. Sci., December 1, 1999; 40(13): 3075 - 3078.
[Full Text] [PDF]

Y. Uteza, J.-S. Rouillot, A. Kobetz, D. Marchant, S. Pecqueur, E. Arnaud, H. Prats, J. Honiger, J.-L. Dufier, M. Abitbol, et al.
Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2�delays photoreceptor cell degeneration in Royal College of Surgeons rats
PNAS, March 16, 1999; 96(6): 3126 - 3131.
[Abstract] [Full Text] [PDF]

L. Legeai-Mallet, C. Benoist-Lasselin, A.-L. Delezoide, A. Munnich, and J. Bonaventure
Fibroblast Growth Factor Receptor 3�Mutations Promote Apoptosis but Do Not Alter Chondrocyte Proliferation in Thanatophoric Dysplasia
J. Biol. Chem., May 22, 1998; 273(21): 13007 - 13014.
[Abstract] [Full Text] [PDF]

S. Ortega, M. Ittmann, S. H. Tsang, M. Ehrlich, and C. Basilico
Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2
PNAS, May 12, 1998; 95(10): 5672 - 5677.
[Abstract] [Full Text] [PDF]

Y. Ishizaki, M. D. Jacobson, and M. C. Raff
A Role for Caspases in Lens Fiber Differentiation
J. Cell Biol., January 12, 1998; 140(1): 153 - 158.
[Abstract] [Full Text] [PDF]

F. Lovicu and P. Overbeek
Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice
Development, January 9, 1998; 125(17): 3365 - 3377.
[Abstract] [PDF]

K. Del Rio-Tsonis, J. C. Jung, I.-M. Chiu, and P. A. Tsonis
Conservation of fibroblast growth factor function in lens�regeneration
PNAS, December 9, 1997; 94(25): 13701 - 13706.
[Abstract] [Full Text] [PDF]

S. Bassnett and D. Mataic
Chromatin Degradation in Differentiating Fiber Cells of the Eye Lens
J. Cell Biol., April 7, 1997; 137(1): 37 - 49.
[Abstract] [Full Text] [PDF]

C. Stolen, M. Jackson, and A. Griep
Overexpression of FGF-2 modulates fiber cell differentiation and survival in the mouse lens
Development, January 10, 1997; 124(20): 4009 - 4017.
[Abstract] [PDF]

M. P. Trolice, A. Pappalardo, and J. J. Peluso
Basic Fibroblast Growth Factor and N-Cadherin Maintain Rat Granulosa Cell and Ovarian Surface Epithelial Cell Viability by Stimulating the Tyrosine Phosphorylation of the Fibroblast Growth Factor Receptors
Endocrinology, January 1, 1997; 138(1): 107 - 113.
[Abstract] [Full Text] [PDF]

A Meeson, M Palmer, M Calfon, and R Lang
A relationship between apoptosis and flow during programmed capillary regression is revealed by vital analysis
Development, January 12, 1996; 122(12): 3929 - 3938.
[Abstract] [PDF]

M. Robinson, L. MacMillan-Crow, J. Thompson, and P. Overbeek
Expression of a truncated FGF receptor results in defective lens development in transgenic mice
Development, January 12, 1995; 121(12): 3959 - 3967.
[Abstract] [PDF]

S. H. Ong, Y. R. Hadari, N. Gotoh, G. R. Guy, J. Schlessinger, and I. Lax
Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins
PNAS, May 22, 2001; 98(11): 6074 - 6079.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Chow, R. L.

Articles by Lang, R. A.

Search for Related Content

PubMed

PubMed Citation

Articles by Chow, R. L.

Articles by Lang, R. A.

Social Bookmarking

What's this?

				R. Simon and T. Lufkin Postnatal Lethality in Mice Lacking the Sax2 Homeobox Gene Homologous to Drosophila S59/slouch: Evidence for Positive and Negative Autoregulation Mol. Cell. Biol., December 15, 2003; 23(24): 9046 - 9060. [Abstract] [Full Text] [PDF]

				V. Traverso, N. Kinkl, L. Grimm, J. Sahel, and D. Hicks Basic Fibroblast and Epidermal Growth Factors Stimulate Survival in Adult Porcine Photoreceptor Cell Cultures Invest. Ophthalmol. Vis. Sci., October 1, 2003; 44(10): 4550 - 4558. [Abstract] [Full Text] [PDF]

				T. L. Belecky-Adams, R. Adler, and D. C. Beebe Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation Development, March 10, 2003; 129(16): 3795 - 3802. [Abstract] [Full Text] [PDF]

				J.-X. Huang, M. Feldmeier, Y.-B. Shui, and D. C. Beebe Evaluation of Fibroblast Growth Factor Signaling during Lens Fiber Cell Differentiation Invest. Ophthalmol. Vis. Sci., February 1, 2003; 44(2): 680 - 690. [Abstract] [Full Text] [PDF]

				S. C. Faber, M. L. Robinson, H. P. Makarenkova, and R. A. Lang Bmp signaling is required for development of primary lens fiber cells Development, August 1, 2002; 129(15): 3727 - 3737. [Abstract] [Full Text] [PDF]

				F. J. Lovicu and J. W. McAvoy FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling Development, December 15, 2001; 128(24): 5075 - 5084. [Abstract] [Full Text] [PDF]

				S. C. Faber, P. Dimanlig, H. P. Makarenkova, S. Shirke, K. Ko, and R. A. Lang Fgf receptor signaling plays a role in lens induction Development, November 15, 2001; 128(22): 4425 - 4438. [Abstract] [Full Text] [PDF]

				A.-C. N. Le and L. S. Musil A novel role for FGF and extracellular signal-regulated kinase in gap junction-mediated intercellular communication in the lens J. Cell Biol., July 9, 2001; 154(1): 197 - 216. [Abstract] [Full Text] [PDF]

				I. M. Wormstone, K. Del Rio–Tsonis, G. McMahon, S. Tamiya, P. D. Davies, J. M. Marcantonio, and G. Duncan FGF: An Autocrine Regulator of Human Lens Cell Growth Independent of Added Stimuli Invest. Ophthalmol. Vis. Sci., May 1, 2001; 42(6): 1305 - 1311. [Abstract] [Full Text]

				J. Lemonnier, E. Hay, P. Delannoy, O. Fromigue, A. Lomri, D. Modrowski, and P. J. Marie Increased Osteoblast Apoptosis in Apert Craniosynostosis : Role of Protein Kinase C and Interleukin-1 Am. J. Pathol., May 1, 2001; 158(5): 1833 - 1842. [Abstract] [Full Text] [PDF]

				X. Gong, X. Wang, J. Han, I. Niesman, Q. Huang, and J. Horwitz Development of Cataractous Macrophthalmia in Mice Expressing an Active MEK1 in the Lens Invest. Ophthalmol. Vis. Sci., March 1, 2001; 42(3): 539 - 548. [Abstract] [Full Text]

				V Govindarajan and P. Overbeek Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation Development, January 5, 2001; 128(9): 1617 - 1627. [Abstract] [PDF]

				Y. Ueda, C. G. Chamberlain, K. Satoh, and J. W. McAvoy Inhibition of FGF-Induced {alpha}A-Crystallin Promoter Activity in Lens Epithelial Explants by TGF{beta} Invest. Ophthalmol. Vis. Sci., June 1, 2000; 41(7): 1833 - 1839. [Abstract] [Full Text]

				A. Blixt, M. Mahlapuu, M. Aitola, M. Pelto-Huikko, S. Enerbäck, and P. Carlsson A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle Genes & Dev., January 15, 2000; 14(2): 245 - 254. [Abstract] [Full Text]

				R. A. Lang Which Factors Stimulate Lens Fiber Cell Differentiation In Vivo? Invest. Ophthalmol. Vis. Sci., December 1, 1999; 40(13): 3075 - 3078. [Full Text] [PDF]

				Y. Uteza, J.-S. Rouillot, A. Kobetz, D. Marchant, S. Pecqueur, E. Arnaud, H. Prats, J. Honiger, J.-L. Dufier, M. Abitbol, et al. Intravitreous transplantation of encapsulated fibroblasts secreting the human fibroblast growth factor 2�delays photoreceptor cell degeneration in Royal College of Surgeons rats PNAS, March 16, 1999; 96(6): 3126 - 3131. [Abstract] [Full Text] [PDF]

				L. Legeai-Mallet, C. Benoist-Lasselin, A.-L. Delezoide, A. Munnich, and J. Bonaventure Fibroblast Growth Factor Receptor 3�Mutations Promote Apoptosis but Do Not Alter Chondrocyte Proliferation in Thanatophoric Dysplasia J. Biol. Chem., May 22, 1998; 273(21): 13007 - 13014. [Abstract] [Full Text] [PDF]

				S. Ortega, M. Ittmann, S. H. Tsang, M. Ehrlich, and C. Basilico Neuronal defects and delayed wound healing in mice lacking fibroblast growth factor 2 PNAS, May 12, 1998; 95(10): 5672 - 5677. [Abstract] [Full Text] [PDF]

				Y. Ishizaki, M. D. Jacobson, and M. C. Raff A Role for Caspases in Lens Fiber Differentiation J. Cell Biol., January 12, 1998; 140(1): 153 - 158. [Abstract] [Full Text] [PDF]

				F. Lovicu and P. Overbeek Overlapping effects of different members of the FGF family on lens fiber differentiation in transgenic mice Development, January 9, 1998; 125(17): 3365 - 3377. [Abstract] [PDF]

				K. Del Rio-Tsonis, J. C. Jung, I.-M. Chiu, and P. A. Tsonis Conservation of fibroblast growth factor function in lens�regeneration PNAS, December 9, 1997; 94(25): 13701 - 13706. [Abstract] [Full Text] [PDF]

				S. Bassnett and D. Mataic Chromatin Degradation in Differentiating Fiber Cells of the Eye Lens J. Cell Biol., April 7, 1997; 137(1): 37 - 49. [Abstract] [Full Text] [PDF]

				C. Stolen, M. Jackson, and A. Griep Overexpression of FGF-2 modulates fiber cell differentiation and survival in the mouse lens Development, January 10, 1997; 124(20): 4009 - 4017. [Abstract] [PDF]

				M. P. Trolice, A. Pappalardo, and J. J. Peluso Basic Fibroblast Growth Factor and N-Cadherin Maintain Rat Granulosa Cell and Ovarian Surface Epithelial Cell Viability by Stimulating the Tyrosine Phosphorylation of the Fibroblast Growth Factor Receptors Endocrinology, January 1, 1997; 138(1): 107 - 113. [Abstract] [Full Text] [PDF]

				A Meeson, M Palmer, M Calfon, and R Lang A relationship between apoptosis and flow during programmed capillary regression is revealed by vital analysis Development, January 12, 1996; 122(12): 3929 - 3938. [Abstract] [PDF]

				M. Robinson, L. MacMillan-Crow, J. Thompson, and P. Overbeek Expression of a truncated FGF receptor results in defective lens development in transgenic mice Development, January 12, 1995; 121(12): 3959 - 3967. [Abstract] [PDF]

				S. H. Ong, Y. R. Hadari, N. Gotoh, G. R. Guy, J. Schlessinger, and I. Lax Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins PNAS, May 22, 2001; 98(11): 6074 - 6079. [Abstract] [Full Text] [PDF]