The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Crossley, P. H.
	Articles by Martin, G. R.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Crossley, P. H.
	Articles by Martin, G. R.

Amaya, E., Musci, T. J. and Kirschner, M. W (1991). Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.[Medline]

Amaya, E., Stein, P. A., Musci, T. J. and Kirschner, M. W (1993). FGF signaling in the early specification of mesoderm in Xenopus. Development 118, 477-487.[Abstract]

Baird, A (1994). Fibroblast growth factors: activities and significance of non-neurotrophin neurotrophic growth factors. Curr. Opin. Neurobiol 4, 78-86.[Medline]

Bally-Cuif, L., Alvarado-Mallart, R.-M., Darnell, D. and Wassef, M (1992). Relationship between Wnt-1 and En-2 expression domains during early development of normal and ectopic met-mesencephalon. Development 115, 999-1009.[Abstract]

Basilico, C. and Moscatelli, D (1992). The FGF family of growth factors and oncogenes. Adv. Cancer Res 59, 115-165.[Medline]

Bastian, H. and Gruss, P (1990). A murine even-skipped homologue, Evx 1 , is expressed during early embryogenesis and neurogenesis in a biphasic manner. EMBO J 9, 1839-1852.[Medline]

Bellosta, P., Talarico, D., Rogers, D. and Basilico, C (1993). Cleavage of K-FGF produces a truncated molecule with increased biological activity and receptor binding affinity. J. Cell Biol 121, 705-713.[Abstract/Free Full Text]

Blum, M., Gaunt, S. J., Cho, K. W. Y., Steinbeissser, H., Blumberg, B., Bittner, D. and De Robertis, E. M (1992). Gastrulation in the mouse: the role of the homeobox gene goosecoid. Cell 69, 1097-1106.[Medline]

Blumberg, B., Wright, C., De Robertis, E. and Cho, K (1991). Organizer-specific homeobox genes in Xenopus laevis embryos. Science 253, 194-196.[Abstract/Free Full Text]

Church, G. M. and Gilbert, W (1984). Genomic sequencing. Proc. Natl. Acad. Sci. USA 81, 1991-1995.[Abstract/Free Full Text]

Davies, P., Poirier, C., Deltour, L. and Montagutelli, X (1994). Genetic reassignment of the insulin-1 ( ins1 ) gene to distal mouse chromosome 19. Genomics 21, 665-667.[Medline]

de Lapeyriere, O., Ollendorff, V., Planche, J., Ott, M. O., Pizette, S., Coulier, F. and Birnbaum, D (1993). Expression of the Fgf6 gene is restricted to developing skeletal muscle in the mouse embryo. Development 118, 601-611.[Abstract]

DeRuiter, M., Poelmann, R., VanderPlas-de Vries, I., Mentink, M. and Gittenberger-de Groot, A (1992). The development of the myocardium and endocardium in mouse embryos. Fusion of two heart tubes?. Anat. Embryol 185, 461-473.[Medline]

Dickinson, M. and McMahon, A (1992). The role of Wnt genes in vertebrate development. Curr. Opin. Genet. Dev 2, 562-566.[Medline]

Dono, R. and Zeller, R (1994). Cell-type-specific nuclear translocation of Fibroblast Growth Factor-2 isoforms during chicken kidney and limb morphogenesis. Dev. Biol 163, 316-330.[Medline]

Dush, M. K. and Martin, G. R (1992). Analysis of mouse Evx genes; Evx-1 displays graded expression in the primitive streak. Dev. Biol 151, 273-287.[Medline]

Echelard, Y., Epstein, D., St-Jacques, B., Shen, L., Mohler, J., McMahon, J. and McMahon, A (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.[Medline]

Fallon, J. F., Lopez, A., Ros, M. A., Savage, M. P., Olwin, B. B. and Simandl, B. K (1994). FGF-2: Apical ectodermal ridge growth signal for chick limb development. Science 264, 104-107.[Abstract/Free Full Text]

Frohman, M. A., Boyle, M. and Martin, G. R (1990). Isolation of the mouse Hox-2.9 gene; analysis of embryonic expression suggests that positional information along the anterior-posterior axis is specified by mesoderm. Development 110, 589-607.[Abstract/Free Full Text]

Fu, Y., Spirito, P., Yu, Z., Biro, S., Sasse, J., Lei, J., Ferrans, V., Epstein, S. and Casscells, W (1991). Acidic fibroblast growth factor in the developing rat embryo. J. Cell Biol 114, 1261-1273.[Abstract/Free Full Text]

Gonzalez, A., Buscglia, M., Ong, M. and Baird, A (1990). Distribution of basic Fibroblast Growth Factor in the 18-day rat fetus: localization in the basement membranes of diverse tissues. J. Cell Biol 110, 753-765.[Abstract/Free Full Text]

Han, J.-K. and Martin, G. R (1993). Embryonic expression of Fgf-6 is restricted to the skeletal muscle lineage. Dev. Biol 158, 549-554.[Medline]

Haub, O. and Goldfarb, M (1991). Expression of the fibroblast growh factor-5 gene in the mouse embryo. Development 112, 397-406.[Abstract]

Hebert, J. M., Boyle, M. and Martin, G. R (1991). mRNA localization studies suggest that murine Fibroblast Growth Factor-5 plays a role in gastrulation. Development 112, 407-415.[Abstract]

Hogan, B., Thaller, C. and Eichele, G (1992). Evidence that Hensen's node is a site of retinoic acid synthesis. Nature 359, 237-241.[Medline]

Hornbruch, A. and Wolpert, L (1986). Positional signalling by Hensen's node when grafted to the chick limb bud. J. Embryol. Exp. Morph 94, 257-265.[Medline]

Johnson, D. E. and Williams, L. T (1993). Structural and functional diversity in the FGF receptor multigene family. Adv. Cancer Res 60, 1-41.[Medline]

Kaufman, M. and Navaratnam, B (1981). Early differentiation of the heart in mouse embryos. J. Anat 133, 235-246.[Medline]

Kimelman, D., Christian, J. and Moon, R (1992). Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction. Development 116, 1-9.[Abstract]

Kingsley, D (1994). The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 8, 133-146.[Free Full Text]

Kouhara, H., Koga, M., Kasayama, S., Tanaka, A., Kishimoto, T. and Sato, B (1994). Transforming activity of a newly cloned androgen-induced growth factor. Oncogene 9, 455-462.[Medline]

Lawson, K. A., Meneses, J. J. and Pedersen, R. A (1991). Clonal analysis of epiblast fate during germ layer formation in the mouse embryo. Development 113, 891-911.[Abstract]

Lumsden, A (1988). Spatial organisation of the epithelium and the role of neural crest cells in the initiation of the mammalian tooth germ. Development 103, 155-169.

Mansour, S. L., Goddard, J. M. and Capecchi, M. R (1993). Mice homozygous for a targeted disruption of the proto-oncogene int-2 have developmental defects in the tail and inner ear. Development 117, 13-28.[Abstract]

Marin, F. and Puelles, L (1994). Patterning of the embryonic avian midbrain after experimental inversions: a polarizing activity from the isthmus. Dev. Biol 163, 19-37.[Medline]

Mason, I., Fuller-Pace, F., Smith, R. and Dickson, C (1994). FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalization and epithelial-mesenchymal interactions. Mech. Dev 45, 15-30.[Medline]

Melton, D. and Jessell, T (1993). Diffusible factors in vertebrate embryonic induction. Cell 68, 257-270.

Moon, R. and Christian, J (1992). Competence modifiers synergize with growth factors during mesoderm induction and patterning in Xenopus. Cell 71, 709-712.[Medline]

Niswander, L. and Martin, G. R (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.[Abstract]

Niswander, L. and Martin, G. R (1993). FGF-4 regulates expression of Evx-1 in the developing mouse limb. Development 119, 287-294.[Abstract]

Niswander, L., Tickle, C., Vogel, A., Booth, I. and Martin, G. R (1993). FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587.[Medline]

Niswander, L. A., Jeffrey, S., Martin, G. R. and Tickle, C (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.[Medline]

Nusse, R. and Varmus, H (1992). Wnt genes. Cell 69, 1073-1087.[Medline]

Orr-Urtreger, A., Givol, D., Yayon, A., Yarden, Y. and Lonai, P (1991). Developmental expression of two murine fibroblast growth factor receptors, flg and bek. Development 113, 1419-1434.[Abstract]

Orr-Urtreger, A., Bedford, M. T., Burakova, T., Arman, E., Zimmer, Y., Yayon, A., Givol, D. and Lonai, P (1993). Developmental localization of the splicing alternatives of fibroblast growth factor receptor-2 (FGFR2). Dev Biol 158, 475-86.[Medline]

Parr, B., Shea, M., Vassileva, G. and McMahon, A (1993). Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119, 247-261.[Abstract]

Peters, K. G., Werner, S. and Williams, L. T (1992). Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development 114, 233-243.[Abstract]

Peters, K., Ornitz, D., Werner, S. and Williams, L (1993). Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis. Dev. Biol 155, 423-430.[Medline]

Richman, J. M. and Tickle, C (1989). Epithelia are interchangeable between facial primordia of chick embryos and morphogenesis is controlled by the mesenchyme. Dev. Biol 136, 201-210.[Medline]

Richman, J. M. and Tickle, C (1992). Epithelial-mesenchymal interactions in the outgrowth of limb buds and facial primordia in chick embryos. Dev. Biol 154, 299-308.[Medline]

Riddle, R. D., Johnson, R. L., Laufer, E. and Tabin, C (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.[Medline]

Rijli, M. F., Mark, M., Lakkaraju, S., Dierich, A., Dolle, P. and Chambon, P (1993). A homeotic transformation is generated in the rostral branchial region of the head by disruption of Hoxa-2 , which acts as a selector gene. Cell 75, 1333-1349.[Medline]

Rowe, L., Nadeau, J., Turner, R., Frankel, W., Letts, V., Eppig, J., Ko, M., Thurston, S. and Birkenmeir, E (1994). Maps from two interspecificbackcross DNA panels available as a community genetic mapping resource. Mammal. Genome 5, 253-274.[Medline]

Rubenstein, J., Martinez, S. and Puelles, L (1994). The prosomeric model: a proposal for the organization of the embryonic vertebrate forebrain. Science 266, 578-580.[Free Full Text]

Ruiz i Altaba, A., Choi, T. and Melton, D. A (1991). Expression of the Xhox3 homeobox protein in Xenopus embryos: blocking its early function suggests the requirement of Xhox3 for normal posterior development. Dev. Growth and Diff 33, 651-669.

Ruiz i Altaba, A. and Melton, D. A (1989). Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos. Nature 341, 33-38.[Medline]

Sato, B., Kouhara, H., Koga, M., Kasayama, S., Saito, H., Sumitani, S., Hashimoto, K., Kishimoto, T., Tanaka, A. and Matsumoto, K (1993). Androgen-induced growth factor and its receptor: demonstation of the androgen-induced autocrine loop in mouse mammary carcinoma cells. J. Steroid Biochem. Molec. Biol 47, 91-98.[Medline]

Savage, M. P., Hart, C. E., Riley, B., Sasse, J., Olwin, B. B. and Fallon, J. R (1993). Distribution of FGF-2 suggests it has a role in chick limb bud growth. Dev. Dynamics 198, 159-170.[Medline]

Shackleford, G. M., Willert, K., Wang, J. and Varmus, H (1993). The Wnt1 proto-oncogene induces changes in morphology, gene expression, and growth factor responsiveness in PC12 cells. Neuron 11, 865-875.[Medline]

Stark, K. L., McMahon, J. A. and McMahon, A. P (1991). FGFR-4, a new member of the fibroblast growth factor receptor family expressed in the definitive endoderm and skeletal muscle lineages of the mouse. Development 113, 641-651.[Abstract]

Tabin, C. J (1991). Retinoids, homeoboxes, and growth factors: toward molecular models for limb development. Cell 66, 199-217.[Medline]

Tanaka, A., Miyamoto, K., Minamino, N., Takeda, M., Sato, B., Matsuo, H. and Matsumoto, K (1992). Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc. Natl. Acad. Sci. USA 89, 8928-8932.[Abstract/Free Full Text]

Tickle, C. and Eichele, G (1994). Vertebrate limb development. Annu. Rev. Cell Biol 10, 121-152.

Wanek, N., Muneoka, K., Holler-Dinsmore, G., Burton, R. and Bryant, S. V (1989). A staging system for mouse limb development. J. Exp. Zool 249, 41-49.[Medline]

Wedden, S. E (1987). Epithelial-mesenchymal interactions in the developing chick facial primordia and the target of retinoid action. Development 99, 341-351.[Abstract]

Wilkinson, D. G., Bailes, J. A. and McMahon, A. P (1987). Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo. Cell 50, 79-88.[Medline]

Wilkinson, D. G., Bhatt, S. and McMahon, A. P (1989). Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development. Development 105, 131-136.[Abstract]

Wilkinson, D. G., Peters, G., Dickson, C. and McMahon, A. P (1988). Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. EMBO J 7, 691-695.[Medline]

Yamaguchi, T. P., Conlon, R. A. and Rossant, J (1992). Expression of the fibroblast growth factor receptor FGFR-1/flg during gastrulation and segmentation in the mouse embryo. Dev. Biol 152, 75-88.[Medline]

Yu, Y., Kah, H., Golden, J., Migchielsen, A., Goetzl, E. and Turck, C (1992). An acidic Fibroblast Growth Factor protein generated by alternative splicing acts like and antagonist. J. Exp. Med 175, 1073-1080.[Abstract/Free Full Text]

Z\234\226iga-Mej\222a-Borja, A., Meijers, C. and Zeller, R (1993). Expression of alternatively spliced bFGF first coding exons and antisense mRNAs during chicken embryogenesis. Dev. Biol 157, 110-118.[Medline]

This article has been cited by other articles:

S. Blaess, D. Stephen, and A. L. Joyner
Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling
Development, June 15, 2008; 135(12): 2093 - 2103.
[Abstract] [Full Text] [PDF]

S. L. Lewis, P.-L. Khoo, R. A. De Young, K. Steiner, C. Wilcock, M. Mukhopadhyay, H. Westphal, R. V. Jamieson, L. Robb, and P. P. L. Tam
Dkk1 and Wnt3 interact to control head morphogenesis in the mouse
Development, May 15, 2008; 135(10): 1791 - 1801.
[Abstract] [Full Text] [PDF]

T. Sasaki, H. Nishihara, M. Hirakawa, K. Fujimura, M. Tanaka, N. Kokubo, C. Kimura-Yoshida, I. Matsuo, K. Sumiyama, N. Saitou, et al.
Possible involvement of SINEs in mammalian-specific brain formation
PNAS, March 18, 2008; 105(11): 4220 - 4225.
[Abstract] [Full Text] [PDF]

M. A. Basson, D. Echevarria, C. Petersen Ahn, A. Sudarov, A. L. Joyner, I. J. Mason, S. Martinez, and G. R. Martin
Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development
Development, March 1, 2008; 135(5): 889 - 898.
[Abstract] [Full Text] [PDF]

D. D'Andrea, G. L. Liguori, J. A. Le Good, E. Lonardo, O. Andersson, D. B. Constam, M. G. Persico, and G. Minchiotti
Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction
J. Cell Biol., February 6, 2008; 180(3): 597 - 605.
[Abstract] [Full Text] [PDF]

M. B. Wahl, C. Deng, M. Lewandoski, and O. Pourquie
FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis
Development, November 15, 2007; 134(22): 4033 - 4041.
[Abstract] [Full Text] [PDF]

M. Fernandes, G. Gutin, H. Alcorn, S. K. McConnell, and J. M. Hebert
Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly
Development, November 1, 2007; 134(21): 3789 - 3794.
[Abstract] [Full Text] [PDF]

B. G. Rash and E. A. Grove
Patterning the Dorsal Telencephalon: A Role for Sonic Hedgehog?
J. Neurosci., October 24, 2007; 27(43): 11595 - 11603.
[Abstract] [Full Text] [PDF]

A. Di-Gregorio, M. Sancho, D. W. Stuckey, L. A. Crompton, J. Godwin, Y. Mishina, and T. A. Rodriguez
BMP signalling inhibits premature neural differentiation in the mouse embryo
Development, September 15, 2007; 134(18): 3359 - 3369.
[Abstract] [Full Text] [PDF]

N. Cambray and V. Wilson
Two distinct sources for a population of maturing axial progenitors
Development, August 1, 2007; 134(15): 2829 - 2840.
[Abstract] [Full Text] [PDF]

K. Sugiura, Y.-Q. Su, F. J. Diaz, S. A. Pangas, S. Sharma, K. Wigglesworth, M. J. O'Brien, M. M. Matzuk, S. Shimasaki, and J. J. Eppig
Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells
Development, July 15, 2007; 134(14): 2593 - 2603.
[Abstract] [Full Text] [PDF]

S. K. Sgaier, Z. Lao, M. P. Villanueva, F. Berenshteyn, D. Stephen, R. K. Turnbull, and A. L. Joyner
Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins
Development, June 15, 2007; 134(12): 2325 - 2335.
[Abstract] [Full Text] [PDF]

S. Pajni-Underwood, C. P. Wilson, C. Elder, Y. Mishina, and M. Lewandoski
BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling
Development, June 15, 2007; 134(12): 2359 - 2368.
[Abstract] [Full Text] [PDF]

Q. Guo and J. Y. H. Li
Distinct functions of the major Fgf8 spliceform, Fgf8b, before and during mouse gastrulation
Development, June 15, 2007; 134(12): 2251 - 2260.
[Abstract] [Full Text] [PDF]

J. A. Cholfin and J. L. R. Rubenstein
Patterning of frontal cortex subdivisions by Fgf17
PNAS, May 1, 2007; 104(18): 7652 - 7657.
[Abstract] [Full Text] [PDF]

M. M. Goddeeris, R. Schwartz, J. Klingensmith, and E. N. Meyers
Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development
Development, April 15, 2007; 134(8): 1593 - 1604.
[Abstract] [Full Text] [PDF]

C. L. Andoniadou, M. Signore, E. Sajedi, C. Gaston-Massuet, D. Kelberman, A. J. Burns, N. Itasaki, M. Dattani, and J. P. Martinez-Barbera
Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain
Development, April 15, 2007; 134(8): 1499 - 1508.
[Abstract] [Full Text] [PDF]

C. Guo, H.-Y. Qiu, Y. Huang, H. Chen, R.-Q. Yang, S.-D. Chen, R. L. Johnson, Z.-F. Chen, and Y.-Q. Ding
Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice
Development, January 15, 2007; 134(2): 317 - 325.
[Abstract] [Full Text] [PDF]

P. Hasson, J. Del Buono, and M. P. O. Logan
Tbx5 is dispensable for forelimb outgrowth
Development, January 1, 2007; 134(1): 85 - 92.
[Abstract] [Full Text] [PDF]

V. S. Aggarwal, J. Liao, A. Bondarev, T. Schimmang, M. Lewandoski, J. Locker, A. Shanske, M. Campione, and B. E. Morrow
Dissection of Tbx1 and Fgf interactions in mouse models of 22q11DS suggests functional redundancy
Hum. Mol. Genet., November 1, 2006; 15(21): 3219 - 3228.
[Abstract] [Full Text] [PDF]

Y. Yabuta, K. Kurimoto, Y. Ohinata, Y. Seki, and M. Saitou
Gene Expression Dynamics During Germline Specification in Mice Identified by Quantitative Single-Cell Gene Expression Profiling
Biol Reprod, November 1, 2006; 75(5): 705 - 716.
[Abstract] [Full Text] [PDF]

T. Hirata, M. Nakazawa, O. Muraoka, R. Nakayama, Y. Suda, and M. Hibi
Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions
Development, October 15, 2006; 133(20): 3993 - 4004.
[Abstract] [Full Text] [PDF]

S. D. Weatherbee, R. R. Behringer, J. J. Rasweiler IV, and L. A. Niswander
Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification
PNAS, October 10, 2006; 103(41): 15103 - 15107.
[Abstract] [Full Text] [PDF]

E. Roussa, M. Wiehle, N. Dunker, S. Becker-Katins, O. Oehlke, and K. Krieglstein
Transforming Growth Factor {beta} Is Required for Differentiation of Mouse Mesencephalic Progenitors into Dopaminergic Neurons In Vitro and In Vivo: Ectopic Induction in Dorsal Mesencephalon
Stem Cells, September 1, 2006; 24(9): 2120 - 2129.
[Abstract] [Full Text] [PDF]

C. Chazaud and J. Rossant
Disruption of early proximodistal patterning and AVE formation in Apc mutants
Development, September 1, 2006; 133(17): 3379 - 3387.
[Abstract] [Full Text] [PDF]

J. Morcillo, J. R. Martinez-Morales, F. Trousse, Y. Fermin, J. C. Sowden, and P. Bovolenta
Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH
Development, August 15, 2006; 133(16): 3179 - 3190.
[Abstract] [Full Text] [PDF]

G. Gutin, M. Fernandes, L. Palazzolo, H. Paek, K. Yu, D. M. Ornitz, S. K. McConnell, and J. M. Hebert
FGF signalling generates ventral telencephalic cells independently of SHH
Development, August 1, 2006; 133(15): 2937 - 2946.
[Abstract] [Full Text] [PDF]

C. Wang, C. Xia, W. Bian, L. Liu, W. Lin, Y.-G. Chen, S.-L. Ang, and N. Jing
Cell Aggregation-induced FGF8 Elevation Is Essential for P19 Cell Neural Differentiation
Mol. Biol. Cell, July 1, 2006; 17(7): 3075 - 3084.
[Abstract] [Full Text] [PDF]

A. Marguerie, F. Bajolle, S. Zaffran, N. A. Brown, C. Dickson, M. E. Buckingham, and R. G. Kelly
Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice
Cardiovasc Res, July 1, 2006; 71(1): 50 - 60.
[Abstract] [Full Text] [PDF]

E. J. Park, L. A. Ogden, A. Talbot, S. Evans, C.-L. Cai, B. L. Black, D. U. Frank, and A. M. Moon
Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling
Development, June 15, 2006; 133(12): 2419 - 2433.
[Abstract] [Full Text] [PDF]

R. Ilagan, R. Abu-Issa, D. Brown, Y.-P. Yang, K. Jiao, R. J. Schwartz, J. Klingensmith, and E. N. Meyers
Fgf8 is required for anterior heart field development
Development, June 15, 2006; 133(12): 2435 - 2445.
[Abstract] [Full Text] [PDF]

E. E. Storm, S. Garel, U. Borello, J. M. Hebert, S. Martinez, S. K. McConnell, G. R. Martin, and J. L. R. Rubenstein
Dose-dependent functions of Fgf8 in regulating telencephalic patterning centers
Development, May 1, 2006; 133(9): 1831 - 1844.
[Abstract] [Full Text] [PDF]

S. T. Waters and M. Lewandoski
A threshold requirement for Gbx2 levels in hindbrain development.
Development, May 1, 2006; 133(10): 1991 - 2000.
[Abstract] [Full Text] [PDF]

R. B. Fletcher, J. C. Baker, and R. M. Harland
FGF8 spliceforms mediate early mesoderm and posterior neural tissue formation in Xenopus
Development, May 1, 2006; 133(9): 1703 - 1714.
[Abstract] [Full Text] [PDF]

J. Cai, J. Chen, Y. Liu, T. Miura, Y. Luo, J. F. Loring, W. J. Freed, M. S. Rao, and X. Zeng
Assessing Self-Renewal and Differentiation in Human Embryonic Stem Cell Lines
Stem Cells, March 1, 2006; 24(3): 516 - 530.
[Abstract] [Full Text] [PDF]

H. Sakurai, T. Era, L. M. Jakt, M. Okada, S. Nakai, S. Nishikawa, and S.-I. Nishikawa
In Vitro Modeling of Paraxial and Lateral Mesoderm Differentiation Reveals Early Reversibility
Stem Cells, March 1, 2006; 24(3): 575 - 586.
[Abstract] [Full Text] [PDF]

M. B. Tereshina, A. G. Zaraisky, and V. V. Novoselov
Ras-dva, a member of novel family of small GTPases, is required for the anterior ectoderm patterning in the Xenopus laevis embryo
Development, February 1, 2006; 133(3): 485 - 494.
[Abstract] [Full Text] [PDF]

S. K. Olsen, J. Y.H. Li, C. Bromleigh, A. V. Eliseenkova, O. A. Ibrahimi, Z. Lao, F. Zhang, R. J. Linhardt, A. L. Joyner, and M. Mohammadi
Structural basis by which alternative splicing modulates the organizer activity of FGF8 in the brain
Genes & Dev., January 15, 2006; 20(2): 185 - 198.
[Abstract] [Full Text] [PDF]

E. M. Morin-Kensicki, B. N. Boone, M. Howell, J. R. Stonebraker, J. Teed, J. G. Alb, T. R. Magnuson, W. O'Neal, and S. L. Milgram
Defects in Yolk Sac Vasculogenesis, Chorioallantoic Fusion, and Embryonic Axis Elongation in Mice with Targeted Disruption of Yap65
Mol. Cell. Biol., January 1, 2006; 26(1): 77 - 87.
[Abstract] [Full Text] [PDF]

W. Bai, M. Ishida, M. Okabe, and Y. Arimatsu
Role of the Protomap and Target-derived Signals in the Development of Intrahemispheric Connections
Cereb Cortex, January 1, 2006; 16(1): 124 - 135.
[Abstract] [Full Text] [PDF]

P. Lu, G. Minowada, and G. R. Martin
Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function
Development, January 1, 2006; 133(1): 33 - 42.
[Abstract] [Full Text] [PDF]

J. Chu, J. Ding, K. Jeays-Ward, S. M. Price, M. Placzek, and M. M. Shen
Non-cell-autonomous role for Cripto in axial midline formation during vertebrate embryogenesis
Development, December 15, 2005; 132(24): 5539 - 5551.
[Abstract] [Full Text] [PDF]

S. Kawauchi, J. Shou, R. Santos, J. M. Hebert, S. K. McConnell, I. Mason, and A. L. Calof
Fgf8 expression defines a morphogenetic center required for olfactory neurogenesis and nasal cavity development in the mouse
Development, December 1, 2005; 132(23): 5211 - 5223.
[Abstract] [Full Text] [PDF]

M. Ishii, J. Han, H.-Y. Yen, H. M. Sucov, Y. Chai, and R. E. Maxson Jr
Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest
Development, November 15, 2005; 132(22): 4937 - 4950.
[Abstract] [Full Text] [PDF]

D. Stickens, B. M. Zak, N. Rougier, J. D. Esko, and Z. Werb
Mice deficient in Ext2 lack heparan sulfate and develop exostoses
Development, November 15, 2005; 132(22): 5055 - 5068.
[Abstract] [Full Text] [PDF]

C. Li, X. Xu, D. K. Nelson, T. Williams, M. R. Kuehn, and C.-X. Deng
FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis
Development, November 1, 2005; 132(21): 4755 - 4764.
[Abstract] [Full Text] [PDF]

J. A. Groves, C. L. Hammond, and S. M. Hughes
Fgf8 drives myogenic progression of a novel lateral fast muscle fibre population in zebrafish
Development, October 1, 2005; 132(19): 4211 - 4222.
[Abstract] [Full Text] [PDF]

M. Delfino-Machin, J. S. Lunn, D. N. Breitkreuz, J. Akai, and K. G. Storey
Specification and maintenance of the spinal cord stem zone
Development, October 1, 2005; 132(19): 4273 - 4283.
[Abstract] [Full Text] [PDF]

U. Grieshammer, C. Cebrian, R. Ilagan, E. Meyers, D. Herzlinger, and G. R. Martin
FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons
Development, September 1, 2005; 132(17): 3847 - 3857.
[Abstract] [Full Text] [PDF]

				S. L. Lewis, P.-L. Khoo, R. A. De Young, K. Steiner, C. Wilcock, M. Mukhopadhyay, H. Westphal, R. V. Jamieson, L. Robb, and P. P. L. Tam Dkk1 and Wnt3 interact to control head morphogenesis in the mouse Development, May 15, 2008; 135(10): 1791 - 1801. [Abstract] [Full Text] [PDF]

				T. Sasaki, H. Nishihara, M. Hirakawa, K. Fujimura, M. Tanaka, N. Kokubo, C. Kimura-Yoshida, I. Matsuo, K. Sumiyama, N. Saitou, et al. Possible involvement of SINEs in mammalian-specific brain formation PNAS, March 18, 2008; 105(11): 4220 - 4225. [Abstract] [Full Text] [PDF]

				M. A. Basson, D. Echevarria, C. Petersen Ahn, A. Sudarov, A. L. Joyner, I. J. Mason, S. Martinez, and G. R. Martin Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development Development, March 1, 2008; 135(5): 889 - 898. [Abstract] [Full Text] [PDF]

				D. D'Andrea, G. L. Liguori, J. A. Le Good, E. Lonardo, O. Andersson, D. B. Constam, M. G. Persico, and G. Minchiotti Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction J. Cell Biol., February 6, 2008; 180(3): 597 - 605. [Abstract] [Full Text] [PDF]

				M. B. Wahl, C. Deng, M. Lewandoski, and O. Pourquie FGF signaling acts upstream of the NOTCH and WNT signaling pathways to control segmentation clock oscillations in mouse somitogenesis Development, November 15, 2007; 134(22): 4033 - 4041. [Abstract] [Full Text] [PDF]

				M. Fernandes, G. Gutin, H. Alcorn, S. K. McConnell, and J. M. Hebert Mutations in the BMP pathway in mice support the existence of two molecular classes of holoprosencephaly Development, November 1, 2007; 134(21): 3789 - 3794. [Abstract] [Full Text] [PDF]

				B. G. Rash and E. A. Grove Patterning the Dorsal Telencephalon: A Role for Sonic Hedgehog? J. Neurosci., October 24, 2007; 27(43): 11595 - 11603. [Abstract] [Full Text] [PDF]

				A. Di-Gregorio, M. Sancho, D. W. Stuckey, L. A. Crompton, J. Godwin, Y. Mishina, and T. A. Rodriguez BMP signalling inhibits premature neural differentiation in the mouse embryo Development, September 15, 2007; 134(18): 3359 - 3369. [Abstract] [Full Text] [PDF]

				N. Cambray and V. Wilson Two distinct sources for a population of maturing axial progenitors Development, August 1, 2007; 134(15): 2829 - 2840. [Abstract] [Full Text] [PDF]

				K. Sugiura, Y.-Q. Su, F. J. Diaz, S. A. Pangas, S. Sharma, K. Wigglesworth, M. J. O'Brien, M. M. Matzuk, S. Shimasaki, and J. J. Eppig Oocyte-derived BMP15 and FGFs cooperate to promote glycolysis in cumulus cells Development, July 15, 2007; 134(14): 2593 - 2603. [Abstract] [Full Text] [PDF]

				S. K. Sgaier, Z. Lao, M. P. Villanueva, F. Berenshteyn, D. Stephen, R. K. Turnbull, and A. L. Joyner Genetic subdivision of the tectum and cerebellum into functionally related regions based on differential sensitivity to engrailed proteins Development, June 15, 2007; 134(12): 2325 - 2335. [Abstract] [Full Text] [PDF]

				S. Pajni-Underwood, C. P. Wilson, C. Elder, Y. Mishina, and M. Lewandoski BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling Development, June 15, 2007; 134(12): 2359 - 2368. [Abstract] [Full Text] [PDF]

				Q. Guo and J. Y. H. Li Distinct functions of the major Fgf8 spliceform, Fgf8b, before and during mouse gastrulation Development, June 15, 2007; 134(12): 2251 - 2260. [Abstract] [Full Text] [PDF]

				J. A. Cholfin and J. L. R. Rubenstein Patterning of frontal cortex subdivisions by Fgf17 PNAS, May 1, 2007; 104(18): 7652 - 7657. [Abstract] [Full Text] [PDF]

				M. M. Goddeeris, R. Schwartz, J. Klingensmith, and E. N. Meyers Independent requirements for Hedgehog signaling by both the anterior heart field and neural crest cells for outflow tract development Development, April 15, 2007; 134(8): 1593 - 1604. [Abstract] [Full Text] [PDF]

				C. L. Andoniadou, M. Signore, E. Sajedi, C. Gaston-Massuet, D. Kelberman, A. J. Burns, N. Itasaki, M. Dattani, and J. P. Martinez-Barbera Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain Development, April 15, 2007; 134(8): 1499 - 1508. [Abstract] [Full Text] [PDF]

				C. Guo, H.-Y. Qiu, Y. Huang, H. Chen, R.-Q. Yang, S.-D. Chen, R. L. Johnson, Z.-F. Chen, and Y.-Q. Ding Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice Development, January 15, 2007; 134(2): 317 - 325. [Abstract] [Full Text] [PDF]

				P. Hasson, J. Del Buono, and M. P. O. Logan Tbx5 is dispensable for forelimb outgrowth Development, January 1, 2007; 134(1): 85 - 92. [Abstract] [Full Text] [PDF]

				V. S. Aggarwal, J. Liao, A. Bondarev, T. Schimmang, M. Lewandoski, J. Locker, A. Shanske, M. Campione, and B. E. Morrow Dissection of Tbx1 and Fgf interactions in mouse models of 22q11DS suggests functional redundancy Hum. Mol. Genet., November 1, 2006; 15(21): 3219 - 3228. [Abstract] [Full Text] [PDF]

				Y. Yabuta, K. Kurimoto, Y. Ohinata, Y. Seki, and M. Saitou Gene Expression Dynamics During Germline Specification in Mice Identified by Quantitative Single-Cell Gene Expression Profiling Biol Reprod, November 1, 2006; 75(5): 705 - 716. [Abstract] [Full Text] [PDF]

				T. Hirata, M. Nakazawa, O. Muraoka, R. Nakayama, Y. Suda, and M. Hibi Zinc-finger genes Fez and Fez-like function in the establishment of diencephalon subdivisions Development, October 15, 2006; 133(20): 3993 - 4004. [Abstract] [Full Text] [PDF]

				S. D. Weatherbee, R. R. Behringer, J. J. Rasweiler IV, and L. A. Niswander Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification PNAS, October 10, 2006; 103(41): 15103 - 15107. [Abstract] [Full Text] [PDF]

				E. Roussa, M. Wiehle, N. Dunker, S. Becker-Katins, O. Oehlke, and K. Krieglstein Transforming Growth Factor {beta} Is Required for Differentiation of Mouse Mesencephalic Progenitors into Dopaminergic Neurons In Vitro and In Vivo: Ectopic Induction in Dorsal Mesencephalon Stem Cells, September 1, 2006; 24(9): 2120 - 2129. [Abstract] [Full Text] [PDF]

				C. Chazaud and J. Rossant Disruption of early proximodistal patterning and AVE formation in Apc mutants Development, September 1, 2006; 133(17): 3379 - 3387. [Abstract] [Full Text] [PDF]

				J. Morcillo, J. R. Martinez-Morales, F. Trousse, Y. Fermin, J. C. Sowden, and P. Bovolenta Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH Development, August 15, 2006; 133(16): 3179 - 3190. [Abstract] [Full Text] [PDF]

				G. Gutin, M. Fernandes, L. Palazzolo, H. Paek, K. Yu, D. M. Ornitz, S. K. McConnell, and J. M. Hebert FGF signalling generates ventral telencephalic cells independently of SHH Development, August 1, 2006; 133(15): 2937 - 2946. [Abstract] [Full Text] [PDF]

				C. Wang, C. Xia, W. Bian, L. Liu, W. Lin, Y.-G. Chen, S.-L. Ang, and N. Jing Cell Aggregation-induced FGF8 Elevation Is Essential for P19 Cell Neural Differentiation Mol. Biol. Cell, July 1, 2006; 17(7): 3075 - 3084. [Abstract] [Full Text] [PDF]

				A. Marguerie, F. Bajolle, S. Zaffran, N. A. Brown, C. Dickson, M. E. Buckingham, and R. G. Kelly Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice Cardiovasc Res, July 1, 2006; 71(1): 50 - 60. [Abstract] [Full Text] [PDF]

				E. J. Park, L. A. Ogden, A. Talbot, S. Evans, C.-L. Cai, B. L. Black, D. U. Frank, and A. M. Moon Required, tissue-specific roles for Fgf8 in outflow tract formation and remodeling Development, June 15, 2006; 133(12): 2419 - 2433. [Abstract] [Full Text] [PDF]

				R. Ilagan, R. Abu-Issa, D. Brown, Y.-P. Yang, K. Jiao, R. J. Schwartz, J. Klingensmith, and E. N. Meyers Fgf8 is required for anterior heart field development Development, June 15, 2006; 133(12): 2435 - 2445. [Abstract] [Full Text] [PDF]