Extracellular FGF-1 acts as a lens differentiation factor in transgenic mice

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				S. Singh, M. Robinson, F. Nahi, B. Coley, M. L. Robinson, C. M. Bates, K. Kornacker, and K. M. McHugh Identification of a Unique Transgenic Mouse Line That Develops Megabladder, Obstructive Uropathy, and Renal Dysfunction J. Am. Soc. Nephrol., February 1, 2007; 18(2): 461 - 471. [Abstract] [Full Text] [PDF]

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				H. Huang, F. Li, R. A. Alvarez, J. D. Ash, and R. E. Anderson Downregulation of ATP Synthase Subunit-6, Cytochrome c Oxidase-III, and NADH Dehydrogenase-3 by Bright Cyclic Light in the Rat Retina Invest. Ophthalmol. Vis. Sci., August 1, 2004; 45(8): 2489 - 2496. [Abstract] [Full Text] [PDF]

				H. Zhao, Y. Yang, C. M. Rizo, P. A. Overbeek, and M. L. Robinson Insertion of a Pax6 Consensus Binding Site into the {alpha}A-Crystallin Promoter Acts as a Lens Epithelial Cell Enhancer in Transgenic Mice Invest. Ophthalmol. Vis. Sci., June 1, 2004; 45(6): 1930 - 1939. [Abstract] [Full Text] [PDF]

				F. J. Lovicu, P. Steven, S. Saika, and J. W. McAvoy Aberrant Lens Fiber Differentiation in Anterior Subcapsular Cataract Formation: A Process Dependent on Reduced Levels of Pax6 Invest. Ophthalmol. Vis. Sci., June 1, 2004; 45(6): 1946 - 1953. [Abstract] [Full Text] [PDF]

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				B. E. Davy and M. L. Robinson Congenital hydrocephalus in hy3 mice is caused by a frameshift mutation in Hydin, a large novel gene Hum. Mol. Genet., May 15, 2003; 12(10): 1163 - 1170. [Abstract] [Full Text] [PDF]

				T. L. Belecky-Adams, R. Adler, and D. C. Beebe Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation Development, March 10, 2003; 129(16): 3795 - 3802. [Abstract] [Full Text] [PDF]

				J.-X. Huang, M. Feldmeier, Y.-B. Shui, and D. C. Beebe Evaluation of Fibroblast Growth Factor Signaling during Lens Fiber Cell Differentiation Invest. Ophthalmol. Vis. Sci., February 1, 2003; 44(2): 680 - 690. [Abstract] [Full Text] [PDF]

				H. Ochi, H. Ogino, Y. Kageyama, and K. Yasuda The Stability of the Lens-specific Maf Protein is Regulated by Fibroblast Growth Factor (FGF)/ERK Signaling in Lens Fiber Differentiation J. Biol. Chem., January 3, 2003; 278(1): 537 - 544. [Abstract] [Full Text] [PDF]

				S. C. Faber, M. L. Robinson, H. P. Makarenkova, and R. A. Lang Bmp signaling is required for development of primary lens fiber cells Development, August 1, 2002; 129(15): 3727 - 3737. [Abstract] [Full Text] [PDF]

				Q. Chen, D. H. Dowhan, D. Liang, D. D. Moore, and P. A. Overbeek CREB-binding Protein/p300 Co-activation of Crystallin Gene Expression J. Biol. Chem., June 28, 2002; 277(27): 24081 - 24089. [Abstract] [Full Text] [PDF]

				S. Zhao, F.-C. Hung, J. S. Colvin, A. White, W. Dai, F. J. Lovicu, D. M. Ornitz, and P. A. Overbeek Patterning the optic neuroepithelium by FGF signaling and Ras activation Development, December 15, 2001; 128(24): 5051 - 5060. [Abstract] [Full Text] [PDF]

				F. J. Lovicu and J. W. McAvoy FGF-induced lens cell proliferation and differentiation is dependent on MAPK (ERK1/2) signalling Development, December 15, 2001; 128(24): 5075 - 5084. [Abstract] [Full Text] [PDF]

				S. C. Faber, P. Dimanlig, H. P. Makarenkova, S. Shirke, K. Ko, and R. A. Lang Fgf receptor signaling plays a role in lens induction Development, November 15, 2001; 128(22): 4425 - 4438. [Abstract] [Full Text] [PDF]

				A.-C. N. Le and L. S. Musil A novel role for FGF and extracellular signal-regulated kinase in gap junction-mediated intercellular communication in the lens J. Cell Biol., July 9, 2001; 154(1): 197 - 216. [Abstract] [Full Text] [PDF]

				I. M. Wormstone, K. Del Rio–Tsonis, G. McMahon, S. Tamiya, P. D. Davies, J. M. Marcantonio, and G. Duncan FGF: An Autocrine Regulator of Human Lens Cell Growth Independent of Added Stimuli Invest. Ophthalmol. Vis. Sci., May 1, 2001; 42(6): 1305 - 1311. [Abstract] [Full Text]

				X. Gong, X. Wang, J. Han, I. Niesman, Q. Huang, and J. Horwitz Development of Cataractous Macrophthalmia in Mice Expressing an Active MEK1 in the Lens Invest. Ophthalmol. Vis. Sci., March 1, 2001; 42(3): 539 - 548. [Abstract] [Full Text]

				V Govindarajan and P. Overbeek Secreted FGFR3, but not FGFR1, inhibits lens fiber differentiation Development, January 5, 2001; 128(9): 1617 - 1627. [Abstract] [PDF]

				Q. Chen, F.-C. Hung, L. Fromm, and P. A. Overbeek Induction of Cell Cycle Entry and Cell Death in Postmitotic Lens Fiber Cells by Overexpression of E2F1 or E2F2 Invest. Ophthalmol. Vis. Sci., December 1, 2000; 41(13): 4223 - 4231. [Abstract] [Full Text]

				Y. Ueda, C. G. Chamberlain, K. Satoh, and J. W. McAvoy Inhibition of FGF-Induced {alpha}A-Crystallin Promoter Activity in Lens Epithelial Explants by TGF{beta} Invest. Ophthalmol. Vis. Sci., June 1, 2000; 41(7): 1833 - 1839. [Abstract] [Full Text]

				M. Duncan, Z Kozmik, K Cveklova, J Piatigorsky, and A Cvekl Overexpression of PAX6(5a) in lens fiber cells results in cataract and upregulation of (alpha)5(beta)1 integrin expression J. Cell Sci., January 9, 2000; 113(18): 3173 - 3185. [Abstract] [PDF]

				L. Reneker, D. Silversides, L Xu, and P. Overbeek Formation of corneal endothelium is essential for anterior segment development - a transgenic mouse model of anterior segment dysgenesis Development, January 2, 2000; 127(3): 533 - 542. [Abstract] [PDF]

				B. Ring, S. Cordes, P. Overbeek, and G. Barsh Regulation of mouse lens fiber cell development and differentiation by the Maf gene Development, January 1, 2000; 127(2): 307 - 317. [Abstract] [PDF]

				R. A. Lang Which Factors Stimulate Lens Fiber Cell Differentiation In Vivo? Invest. Ophthalmol. Vis. Sci., December 1, 1999; 40(13): 3075 - 3078. [Full Text] [PDF]

				P. R. Cammarata, C. Zhou, G. Chen, I. Singh, R. E. Reeves, J. R. Kuszak, and M. L. Robinson A Transgenic Animal Model of Osmotic Cataract. Part 1: Over-expression of Bovine Na+/Myo-inositol Cotransporter in Lens Fibers Invest. Ophthalmol. Vis. Sci., July 1, 1999; 40(8): 1727 - 1737. [Abstract] [Full Text] [PDF]