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Stage-specific Integration of Maternal and Embryonic Peroxisome Proliferator-activated Receptor {delta} Signaling Is Critical to Pregnancy Success
J. Biol. Chem., December 28, 2007; 282(52): 37770 - 37782.
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Proc. Natl. Acad. Sci. USAHome page
C. A. White, J.-G. Zhang, L. A. Salamonsen, M. Baca, W. D. Fairlie, D. Metcalf, N. A. Nicola, L. Robb, and E. Dimitriadis
From the Cover: Blocking LIF action in the uterus by using a PEGylated antagonist prevents implantation: A nonhormonal contraceptive strategy
PNAS, December 4, 2007; 104(49): 19357 - 19362.
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An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor
PNAS, July 31, 2007; 104(31): 12737 - 12742.
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S. Kuure, A. Popsueva, M. Jakobson, K. Sainio, and H. Sariola
Glycogen Synthase Kinase-3 Inactivation and Stabilization of beta-Catenin Induce Nephron Differentiation in Isolated Mouse and Rat Kidney Mesenchymes
J. Am. Soc. Nephrol., April 1, 2007; 18(4): 1130 - 1139.
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Leukemia Inhibitory Factor Induces Endothelial Differentiation in Cardiac Stem Cells
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S. Oberle, A. Schober, V. Meyer, B. Holtmann, C. Henderson, M. Sendtner, and K. Unsicker
Loss of Leukemia Inhibitory Factor Receptor beta or Cardiotrophin-1 Causes Similar Deficits in Preganglionic Sympathetic Neurons and Adrenal Medulla
J. Neurosci., February 8, 2006; 26(6): 1823 - 1832.
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Hum Reprod UpdateHome page
E. Dimitriadis, C.A. White, R.L. Jones, and L.A. Salamonsen
Cytokines, chemokines and growth factors in endometrium related to implantation
Hum. Reprod. Update, November 1, 2005; 11(6): 613 - 630.
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ReproductionHome page
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Leukaemia inhibitory factor in implantation and uterine biology
Reproduction, August 1, 2005; 130(2): 131 - 145.
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PhysiologyHome page
E. D. Watson and J. C. Cross
Development of Structures and Transport Functions in the Mouse Placenta
Physiology, June 1, 2005; 20(3): 180 - 193.
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BloodHome page
B. J. Jenkins, A. W. Roberts, M. Najdovska, D. Grail, and M. Ernst
The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis
Blood, May 1, 2005; 105(9): 3512 - 3520.
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T. Kuroda, M. Tada, H. Kubota, H. Kimura, S.-y. Hatano, H. Suemori, N. Nakatsuji, and T. Tada
Octamer and Sox Elements Are Required for Transcriptional cis Regulation of Nanog Gene Expression
Mol. Cell. Biol., March 15, 2005; 25(6): 2475 - 2485.
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Identification of the Leukemia Inhibitory Factor Cell Targets Within the Rat Testis
Biol Reprod, March 1, 2005; 72(3): 602 - 611.
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ReproductionHome page
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Embryonic diapause and its regulation
Reproduction, December 1, 2004; 128(6): 669 - 678.
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M. C. Horowitz, Y. Xi, D. L. Pflugh, D. G. T. Hesslein, D. G. Schatz, J. A. Lorenzo, and A. L. M. Bothwell
Pax5-Deficient Mice Exhibit Early Onset Osteopenia with Increased Osteoclast Progenitors
J. Immunol., December 1, 2004; 173(11): 6583 - 6591.
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A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis
PNAS, August 24, 2004; 101(34): 12555 - 12560.
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EndocrinologyHome page
R. R. Gonzalez, B. R. Rueda, M. P. Ramos, R. D. Littell, S. Glasser, and P. C. Leavis
Leptin-Induced Increase in Leukemia Inhibitory Factor and Its Receptor by Human Endometrium Is Partially Mediated by Interleukin 1 Receptor Signaling
Endocrinology, August 1, 2004; 145(8): 3850 - 3857.
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Mol Hum ReprodHome page
I. Classen-Linke, G. Muller-Newen, P.C. Heinrich, H.M. Beier, and U. von Rango
The cytokine receptor gp130 and its soluble form are under hormonal control in human endometrium and decidua
Mol. Hum. Reprod., July 1, 2004; 10(7): 495 - 504.
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S. K. Dey, H. Lim, S. K. Das, J. Reese, B. C. Paria, T. Daikoku, and H. Wang
Molecular Cues to Implantation
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Arterioscler. Thromb. Vasc. Bio.Home page
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Role of Tissue Factor in Hemostasis, Thrombosis, and Vascular Development
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Hum Reprod UpdateHome page
M. De Felici, M.L. Scaldaferri, M. Lobascio, S. Iona, V. Nazzicone, F.G. Klinger, and D. Farini
Experimental approaches to the study of primordial germ cell lineage and proliferation
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Immunocytochemical detection and RT-PCR expression of leukaemia inhibitory factor and its receptor in human fetal and adult ovaries
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Cited1 Is Required in Trophoblasts for Placental Development and for Embryo Growth and Survival
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Effects of Leptin and Leukemia Inhibitory Factor on Preimplantation Development and STAT3 Signaling of Mouse Embryos In Vitro
Biol Reprod, November 1, 2003; 69(5): 1531 - 1538.
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BloodHome page
M. Tanaka, Y. Hirabayashi, T. Sekiguchi, T. Inoue, M. Katsuki, and A. Miyajima
Targeted disruption of oncostatin M receptor results in altered hematopoiesis
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Y. P. Ng, W. He, and N. Y. Ip
Leukemia Inhibitory Factor Receptor Signaling Negatively Modulates Nerve Growth Factor-induced Neurite Outgrowth in PC12 Cells and Sympathetic Neurons
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DevelopmentHome page
K. A. Molyneaux, K. Schaible, and C. Wylie
GP130, the shared receptor for the LIF/IL6 cytokine family in the mouse, is not required for early germ cell differentiation, but is required cell-autonomously in oocytes for ovulation
Development, September 15, 2003; 130(18): 4287 - 4294.
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Pulmonary Expression of Leukemia Inhibitory Factor Induces B Cell Hyperplasia and Confers Protection in Hyperoxia
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B. Stankoff, M.-S. Aigrot, F. Noel, A. Wattilliaux, B. Zalc, and C. Lubetzki
Ciliary Neurotrophic Factor (CNTF) Enhances Myelin Formation: A Novel Role for CNTF and CNTF-Related Molecules
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IL-6, Leukemia Inhibitory Factor, and Oncostatin M Stimulate Bone Resorption and Regulate the Expression of Receptor Activator of NF-{kappa}B Ligand, Osteoprotegerin, and Receptor Activator of NF-{kappa}B in Mouse Calvariae
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K. Ozaki and W. J. Leonard
Cytokine and Cytokine Receptor Pleiotropy and Redundancy
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The Role of gp130 in Cerebral Cortical Development: In Vivo Functional Analysis in a Mouse Exo Utero System
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Cardiotrophin-1 Stimulation of Cardiac Fibroblast Growth: Roles for Glycoprotein 130/Leukemia Inhibitory Factor Receptor and the Endothelin Type A Receptor
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T. Shimazaki, T. Shingo, and S. Weiss
The Ciliary Neurotrophic Factor/Leukemia Inhibitory Factor/gp130 Receptor Complex Operates in the Maintenance of Mammalian Forebrain Neural Stem Cells
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Placental defects and embryonic lethality in mice lacking suppressor of cytokine signaling 3
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JEMHome page
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Defective Gp130-Mediated Signal Transducer and Activator of Transcription (Stat) Signaling Results in Degenerative Joint Disease, Gastrointestinal Ulceration, and Failure of Uterine Implantation
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H. Mi, H. Haeberle, and B. A. Barres
Induction of Astrocyte Differentiation by Endothelial Cells
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EndocrinologyHome page
J. R. Chen, J.-G. Cheng, T. Shatzer, L. Sewell, L. Hernandez, and C. L. Stewart
Leukemia Inhibitory Factor Can Substitute for Nidatory Estrogen and Is Essential to Inducing a Receptive Uterus for Implantation But Is Not Essential for Subsequent Embryogenesis
Endocrinology, December 1, 2000; 141(12): 4365 - 4372.
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FASEB J.Home page
D. DUVAL, B. REINHARDT, C. KEDINGER, and H. BOEUF
Role of suppressors of cytokine signaling (Socs) in leukemia inhibitory factor (LIF) -dependent embryonic stem cell survival
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B. Nait–Oumesmar, A. B. Copperman, and R. A. Lazzarini
Placental Expression and Chromosomal Localization of the Human Gcm 1 Gene
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C. Passavant, X. Zhao, S.K. Das, S.K. Dey, and R.A. Mead
Changes in Uterine Expression of Leukemia Inhibitory Factor Receptor Gene During Pregnancy and Its Up-Regulation by Prolactin in the Western Spotted Skunk
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M. Itoh, Y. Yoshida, K. Nishida, M. Narimatsu, M. Hibi, and T. Hirano
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Leukemia Inhibitory Factor Modulates Cardiogenesis in Embryoid Bodies in Opposite Fashions
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Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis
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J. A. Bowen and J. S. Hunt
The Role of Integrins in Reproduction
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Intracellular and Extracellular Leukemia Inhibitory Factor Proteins Have Different Cellular Activities That Are Mediated by Distinct Protein Motifs
Mol. Biol. Cell, April 1, 2000; 11(4): 1369 - 1383.
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EndocrinologyHome page
C. Piquet-Pellorce, I. Dorval-Coiffec, M.-D. Pham, and B. Jegou
Leukemia Inhibitory Factor Expression and Regulation within the Testis
Endocrinology, March 1, 2000; 141(3): 1136 - 1141.
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C. Olivier, P. Auguste, M. Chabbert, E. Lelievre, S. Chevalier, and H. Gascan
Identification of a gp130 Cytokine Receptor Critical Site Involved in Oncostatin M Response
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H Paradis and R. Gendron
LIF transduces contradictory signals on capillary outgrowth through induction of stat3 and (P41/43)MAP kinase
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M. A. Lane, A. C. Chen, S. D. Roman, F. Derguini, and L. J. Gudas
Removal of LIF (leukemia inhibitory factor) results in increased vitamin A (retinol) metabolism to 4-oxoretinol in embryonic stem cells
PNAS, November 9, 1999; 96(23): 13524 - 13529.
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Leukemia Inhibitory Factor and Its Receptor Promote Adipocyte Differentiation via the Mitogen-activated Protein Kinase Cascade
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Tissue factor is required for uterine hemostasis and maintenance of the placental labyrinth during gestation
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BloodHome page
M. Tomida, T. Heike, and T. Yokota
Cytoplasmic Domains of the Leukemia Inhibitory Factor Receptor Required for STAT3 Activation, Differentiation, and Growth Arrest of Myeloid Leukemic Cells
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J Rathjen, J. Lake, M. Bettess, J. Washington, G Chapman, and P. Rathjen
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Postnatally Induced Inactivation of gp130 in Mice Results in Neurological, Cardiac, Hematopoietic, Immunological, Hepatic, and Pulmonary Defects
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M. Peters, A. M. Muller, and S. Rose-John
Interleukin-6 and Soluble Interleukin-6 Receptor: Direct Stimulation of gp130 and Hematopoiesis
Blood, November 15, 1998; 92(10): 3495 - 3504.
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C. M. Owczarek, Y. Zhang, M. J. Layton, D. Metcalf, B. Roberts, and N. A. Nicola
The Unusual Species Cross-reactivity of the Leukemia Inhibitory Factor Receptor alpha -Chain Is Determined Primarily by the Immunoglobulin-like Domain
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EndocrinologyHome page
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Proc. Natl. Acad. Sci. USAHome page
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C. M. Owczarek, M. J. Layton, L. G. Robb, N. A. Nicola, and C. G. Begley
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