Role of MAP kinase in mesoderm induction and axial patterning during Xenopus development

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by LaBonne, C.
	Articles by Whitman, M.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by LaBonne, C.
	Articles by Whitman, M.


Social Bookmarking

	What's this?

Alessi, D., Smythe, C. and Keyse, S. ( (1993). The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and supresses its activation by oncogenic ras in Xenopus oocyte extracts. Oncogene 8, 2015-20.[Medline]

Amaya, E., Musci, T. J. and Kirschner, M. W. ( (1991). Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.[Medline]

Biggs, W., Zavitz, K., Dickson, B., van der Straten, A., Brunner, D., Hafen, E. and Zipursky, S. ( (1994). The Drosophila rolled locus encodes a MAP kinase required in the sevenless signal transduction pathway. EMBO J._Fb_Blenis, J. ( 1993). Signal Transduction via the MAP kinases: Proceed at your own RSK. Proc. Natl. Acad. Sci. USA 90, 5899-5892.

Brunner, D., Oellers, N., Szabad, J., Biggs, W. H., Zipursky, S. L. and Hafen, E. ( (1994). A gain of function mutation in Drosophila MAP kinase activates multiple receptor kinase signaling pathways. Cell 76, 875-888.[Medline]

Cai, H., Szeberenyi, J. and Cooper, G. ( (1990). Effect of a dominant inhibitory Ha-ras mutation on mitogenic signal transduction in NIH 3T3 cells. Molec. Cell. Biol 10, 5314-5323.[Abstract/Free Full Text]

Cascio, S. and Gurdon, J. B. ( (1987). The initiation of new gene transcription during Xenopus gastrulation requires immediately preceding protein synthesis. Development 100, 297-305.[Abstract/Free Full Text]

Charles, C., Sun, H., Lau, L. and Tonks, N. ( (1993). The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proc. Natl. Acad. Sci. USA 90, 5292-6.[Abstract/Free Full Text]

Cornell, R. A. and Kimelman, D. ( (1994). Activin-mediated mesoderm induction requires FGF. Development 120, 453-462.[Abstract]

Cowley, S., Paterson, H., Kemp, P. and Marshall, C. J. ( (1994). Activation of MAP kinase is necessary and sufficient for PC12 Differentiation and for transformation of NIH 3T3 cells. Cell 77, 841-852.[Medline]

Cunliffe, V. and Smith, J. C. ( (1992). Ectopic mesoderm formation in Xenopus embryos caused by widespread expression of a Brachyury homologue. Nature 358, 427-430.[Medline]

Dale, L., Howes, G.,Price, B. M. J. and Smith, J. C. ( (1992). Bone Morphogenetic Protein 4: a ventralizing factor in Xenopus development. Development 115, 573-585.[Abstract]

Dale, L., Matthews, G. and Colman, A. ( (1993). Secretion and mesoderm inducing activity of the TGF\247 related domain of Xenopus Vg1. EMBO J 12, 4471-4480.[Medline]

Dent, P., Haystead, T. A. J., Haser, W., Vincent, L. A., Roberts, T. M. and Sturgill, T. W. ( (1992). v-Raf protein kinase activates mitogen activated protein (MAP) kinase kinase in NIH 3T3 cells and in vitro. Science 257, 1404-1407.[Abstract/Free Full Text]

Graves, L. M., Northrup, J. L., Potts, B. C., Krebs, E. G. and Kimelman, D. ( (1994). Fibroblast growth factor, but not activin, is a potent activator of mitogen-activated protein kinase in Xenopus explants. Proc. Nat. Acad. Sci. USA 91, 1662-1666.[Abstract/Free Full Text]

Gurdon, J. B., Fairman, S., Mohun, T. J. and Brennan, S. ( (1985). Activation of muscle specific actin genes in Xenopus development by an induction between animal and vegetal cells of a blastula. Cell 41, 913-922.[Medline]

Haccard, O., Sarcevic, B., Lewellyn, A., Hartley, R., Roy, L., Izumi, T., Erikson, E. and Maller, J. L. ( (1993). Induction of metaphase arrest in cleaving xenopus embryos by map kinase. Science 262, 1262-1265.[Abstract/Free Full Text]

Hartley, R. S., Lewellyn, A. L. and Maller, J. L. ( (1994). Map kinase is activated during mesoderm induction in Xenopus laevis. Dev. Biol 163, 521-524.[Medline]

Hemmati-Brivanlou, A. and Melton, D. A. ( (1992). A truncated activin receptor dominantly inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359, 609-614.[Medline]

Howe, L. R., Leevers, S. J., Gomez, N., Nakielny, S., Cohen, P. and Marshall, C. J. ( (1992). Activation of the MAP kinase pathway by the protein kinase raf. Cell 71, 335-342.[Medline]

Isaacs, H., Pownall, M. and Slack, J. ( (1994). eFGF regulates Xbra expression during Xenopus gastrulation. EMBO J 13, 4469-4481.[Medline]

Isaacs, H., Tannahill, D. and Slack, J. ( (1992). Expression of a novel FGF in the Xenopus embryo. A new candidate inducing factor for mesoderm formation and anterioposterior specification. Development 114, 711-720.[Abstract]

Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. E., Hogan, B. J. M. ( (1992). DVR-4 (Bone Morphogenetic Protein-4) as a postero-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.[Abstract]

Kimelman, D., Abraham, J. A., Haaparanta, T., Palishi, T. M. and Kirschner, M. W. ( (1988). The presence of fibroblast growth factor in the frog egg: its role as a natural mesoderm inducer. Science 242, 1053-1056.[Abstract/Free Full Text]

Kintner, C. R. and Brockes, J. P. ( (1984). Monoclonal antibodies identify blastemal cells derived from dedifferentiating muscle in newt limb regeneration. Nature 308, 67-69.[Medline]

Koster, M., Plessow, S., Clement, J. H., Lorenz, A., Tiedemann, H. and Knochel, W. ( (1991). Bone Morphogenetic Protein 4 (BMP4), a member of the TGF-family, in early embryos of Xenopus laevis : analysis of mesoderm inducing activity. Mech. Devel 33, 191-200.[Medline]

Krieg, P. A. and Melton, D. A. ( (1987). An enhancer responsible for activating transcription at the MBT in Xenopus development. Proc. Natl. Acad. Sci. USA 84, 2331-2335.[Abstract/Free Full Text]

Kyriakis, J. M., App, H., Zhang, X.-F., Banerjee, P., Brautigan, D. L., Rapp, U. R. and Avruch, J. ( (1992). Raf-1 activates MAP kinase-kinase. Nature 358, 417-421.[Medline]

LaBonne, C. and Whitman, M. ( (1994). Mesoderm induction by activin requires FGF mediated intracellular signals. Development 120, 463-472.[Abstract]

MacNicol, A. M., Muslin, A. J. and Williams, L. T. ( (1993). Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF. Cell 73, 571-584.[Medline]

Mansour, S. J., Matten, W. T., Hermann, A. S., Candia, J. M., Rong, S., Fukasawa, K., Woude, G. F. V. and Ahn, N. G. ( (1994). Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265, 966-969.[Abstract/Free Full Text]

Newport, J. and Kirschner, M. ( (1982). A major developmental transition in early Xenopus embryos: 1. Characterization and timing of cellular changes at the midblastula transition. Cell 30, 675-686.[Medline]

Rao, Y. ( (1994). Conversion of a mesodermalizing molecule, the Xenopus Brachyury gene, into a neuralizing factor. Genes Dev 11, 939-947.

Rosa, F. M. ( (1989). Mix. 1, a homeobox mRNA inducible by mesoderm inducers, is expressed mostly in the presumptive endodermal cells of Xenopus embryos. Cell 57, 965-974.[Medline]

Schultemerker, S., Smith, J. C. and Dale, L. ( (1994). Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of bvg1 and activin- does activin play a role in mesoderm induction. EMBO J 131, 3533-3541.

Slack, J. M. W., Isaacs, H. V. and Darlington, B. G (1988). Inductive effects of fibroblast growth factor and lithium ion on Xenopus blastula ectoderm. Development 103, 581-590.[Abstract]

Smith, J. C. ( (1987). A mesoderm-inducing factor is produced by a Xenopus cell line. Development 99, 3-14.[Abstract/Free Full Text]

Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. and Hermann, B. G (1991). Expression of a Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.[Medline]

Sun, H., Charles, C., Lau, L. and Tonks, N. ( (1993). MKP-1(3CH134) an immediate early gene product, is a dual specificity phosphatase that dephosporylates MAP Kinase in vivo. Cell 75, 487-493.[Medline]

Sun, H., Tonks, N. K. and Bar-Sagi, D. ( (1994). Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science 266, 285-287.[Abstract/Free Full Text]

Thomas, S. M., DeMarco, M., D'Arcangelo, G., Halegoua, S. and Brugge, J. S. ( (1992). Ras is essential for nerve growth factor-and phorbol ester-induced tyrosine phosphorylation of MAP kinases. Cell 68, 1031-1040.[Medline]

Thomsen, G. and Melton, D. ( (1993). Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell 74, 433-441.[Medline]

Whitman, M. and Melton, D. ( (1992). Involvement of p21 ras in Xenopus mesoderm induction. Nature 357, 252-255.[Medline]

Wood, K. W., Sarnecki, C., Roberts, T. and Blenis, J. ( (1992). Ras mediates nerve growth factor receptor modulation of three signal transducing proteins: MAP kinase, Raf-1, and RSK. Cell 68, 1041-1050.[Medline]

Xu, H. P., White, M., Marcus, S. and Wigler, M. ( (1994). Concerted action of RAS and G proteins in the sexual response pathways of Schizoszccharomyces pombe. Mol. Cell Biol 14, 50-58.[Abstract/Free Full Text]

Zaitsevskaya, T. and Cooper, J. ( (1992). Developmentally-regulated expression of mitogen-activated (MAP) kinase in Xenopuslaevis. Cell Growth and Diff 3, 773-782.[Abstract]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

T. Haremaki, S. T. Fraser, Y.-M. Kuo, M. H. Baron, and D. C. Weinstein
Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation
PNAS, July 17, 2007; 104(29): 12029 - 12034.
[Abstract] [Full Text] [PDF]

M. Cordenonsi, M. Montagner, M. Adorno, L. Zacchigna, G. Martello, A. Mamidi, S. Soligo, S. Dupont, and S. Piccolo
Integration of TGF-{beta} and Ras/MAPK Signaling Through p53 Phosphorylation
Science, February 9, 2007; 315(5813): 840 - 843.
[Abstract] [Full Text] [PDF]

R. T. Bottcher and C. Niehrs
Fibroblast Growth Factor Signaling during Early Vertebrate Development
Endocr. Rev., February 1, 2005; 26(1): 63 - 77.
[Abstract] [Full Text] [PDF]

A. P. Myers, L. B. Corson, J. Rossant, and J. C. Baker
Characterization of Mouse Rsk4 as an Inhibitor of Fibroblast Growth Factor-RAS-Extracellular Signal-Regulated Kinase Signaling
Mol. Cell. Biol., May 15, 2004; 24(10): 4255 - 4266.
[Abstract] [Full Text] [PDF]

J. Mathieu, K. Griffin, P. Herbomel, T. Dickmeis, U. Strahle, D. Kimelman, F. M. Rosa, and N. Peyrieras
Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations
Development, February 1, 2004; 131(3): 629 - 641.
[Abstract] [Full Text] [PDF]

L. B. Corson, Y. Yamanaka, K.-M. V. Lai, and J. Rossant
Spatial and temporal patterns of ERK signaling during mouse embryogenesis
Development, October 1, 2003; 130(19): 4527 - 4537.
[Abstract] [Full Text] [PDF]

K. Kawachi, N. Masuyama, and E. Nishida
Essential Role of the Transcription Factor Ets-2 in Xenopus Early Development
J. Biol. Chem., February 7, 2003; 278(7): 5473 - 5477.
[Abstract] [Full Text] [PDF]

M. Funaba, C. M. Zimmerman, and L. S. Mathews
Modulation of Smad2-mediated Signaling by Extracellular Signal-regulated Kinase
J. Biol. Chem., October 25, 2002; 277(44): 41361 - 41368.
[Abstract] [Full Text] [PDF]

K. Mood, R. Friesel, and I. O. Daar
SNT1/FRS2 Mediates Germinal Vesicle Breakdown Induced by an Activated FGF Receptor1 in Xenopus Oocytes
J. Biol. Chem., August 30, 2002; 277(36): 33196 - 33204.
[Abstract] [Full Text] [PDF]

E. K. Park, N. Warner, K. Mood, T. Pawson, and I. O. Daar
Low-Molecular-Weight Protein Tyrosine Phosphatase Is a Positive Component of the Fibroblast Growth Factor Receptor Signaling Pathway
Mol. Cell. Biol., May 15, 2002; 22(10): 3404 - 3414.
[Abstract] [Full Text] [PDF]

R. D. del Corral, D. N. Breitkreuz, and K. G. Storey
Onset of neuronal differentiation is regulated by paraxial mesoderm and requires attenuation of FGF signalling
Development, January 4, 2002; 129(7): 1681 - 1691.
[Abstract] [Full Text] [PDF]

J. A. Greenwald, B. J. Mehrara, J. A. Spector, S. M. Warren, P. J. Fagenholz, L. P. Smith, P. J. Bouletreau, F. E. Crisera, H. Ueno, and M. T. Longaker
In Vivo Modulation of FGF Biological Activity Alters Cranial Suture Fate
Am. J. Pathol., February 1, 2001; 158(2): 441 - 452.
[Abstract] [Full Text] [PDF]

A Abrieu, M Doree, and D Fisher
The interplay between cyclin-B-Cdc2 kinase (MPF) and MAP kinase during maturation of oocytes
J. Cell Sci., January 1, 2001; 114(2): 257 - 267.
[Abstract] [PDF]

R Carballada, H Yasuo, and P Lemaire
Phosphatidylinositol-3 kinase acts in parallel to the ERK MAP kinase in the FGF pathway during Xenopus mesoderm induction
Development, January 1, 2001; 128(1): 35 - 44.
[Abstract] [PDF]

M Umbhauer, A Penzo-Mendez, L Clavilier, J Boucaut, and J Riou
Signaling specificities of fibroblast growth factor receptors in early Xenopus embryo
J. Cell Sci., January 8, 2000; 113(16): 2865 - 2875.
[Abstract] [PDF]

W Lerchner, B. Latinkic, J. Remacle, D Huylebroeck, and J. Smith
Region-specific activation of the Xenopus brachyury promoter involves active repression in ectoderm and endoderm: a study using transgenic frog embryos
Development, January 6, 2000; 127(12): 2729 - 2739.
[Abstract] [PDF]

A. M. O'Reilly, S. Pluskey, S. E. Shoelson, and B. G. Neel
Activated Mutants of SHP-2 Preferentially Induce Elongation of Xenopus Animal Caps
Mol. Cell. Biol., January 1, 2000; 20(1): 299 - 311.
[Abstract] [Full Text]

I. Gotoh, M. Fukuda, M. Adachi, and E. Nishida
Control of the Cell Morphology and the S Phase Entry by Mitogen-activated Protein Kinase Kinase. A REGULATORY ROLE OF ITS N-TERMINAL REGION
J. Biol. Chem., April 23, 1999; 274(17): 11874 - 11880.
[Abstract] [Full Text] [PDF]

M. Wagner, P. Briza, M. Pierce, and E. Winter
Distinct Steps in Yeast Spore Morphogenesis Require Distinct SMK1 MAP Kinase Thresholds
Genetics, April 1, 1999; 151(4): 1327 - 1340.
[Abstract] [Full Text]

K Wunnenberg-Stapleton, I. Blitz, C Hashimoto, and K. Cho
Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development
Development, January 12, 1999; 126(23): 5339 - 5351.
[Abstract] [PDF]

M Watanabe and M Whitman
FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo
Development, January 12, 1999; 126(24): 5621 - 5634.
[Abstract] [PDF]

B Christen and J. Slack
Spatial response to fibroblast growth factor signalling in Xenopus embryos
Development, January 1, 1999; 126(1): 119 - 125.
[Abstract] [PDF]

A. R. Uzgare, J. A. Uzman, H. M. El-Hodiri, and A. K. Sater
Mitogen-activated protein kinase and neural specification in Xenopus
PNAS, December 8, 1998; 95(25): 14833 - 14838.
[Abstract] [Full Text] [PDF]

A. Michelson, S Gisselbrecht, E Buff, and J. Skeath
Heartbroken is a specific downstream mediator of FGF receptor signalling in Drosophila
Development, January 11, 1998; 125(22): 4379 - 4389.
[Abstract] [PDF]

E. Casey, M. O'Reilly, F. Conlon, and J. Smith
The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element
Development, January 10, 1998; 125(19): 3887 - 3894.
[Abstract] [PDF]

M. Fukuda, I. Gotoh, M. Adachi, Y. Gotoh, and E. Nishida
A Novel Regulatory Mechanism in the Mitogen-activated Protein (MAP) Kinase Cascade. ROLE OF NUCLEAR EXPORT SIGNAL OF MAP KINASE KINASE
J. Biol. Chem., December 19, 1997; 272(51): 32642 - 32648.
[Abstract] [Full Text] [PDF]

R. E. Schweppe, A. A. Frazer-Abel, A. Gutierrez-Hartmann, and A. P. Bradford
Functional Components of Fibroblast Growth Factor (FGF) Signal Transduction in Pituitary Cells. IDENTIFICATION OF FGF RESPONSE ELEMENTS IN THE PROLACTIN GENE
J. Biol. Chem., December 5, 1997; 272(49): 30852 - 30859.
[Abstract] [Full Text] [PDF]

R.-H. Xu, J. Kim, M. Taira, D. Sredni, and H.-f. Kung
Studies on the Role of Fibroblast Growth Factor Signaling in Neurogenesis Using Conjugated/Aged Animal Caps and Dorsal Ectoderm-Grafted Embryos
J. Neurosci., September 15, 1997; 17(18): 6892 - 6898.
[Abstract] [Full Text] [PDF]

K. Takenaka, Y. Gotoh, and E. Nishida
MAP Kinase Is Required for the Spindle Assembly Checkpoint but Is Dispensable for the Normal M Phase Entry and Exit in Xenopus Egg Cell Cycle Extracts
J. Cell Biol., March 10, 1997; 136(5): 1091 - 1097.
[Abstract] [Full Text] [PDF]

M Tada, M. O'Reilly, and J. Smith
Analysis of competence and of Brachyury autoinduction by use of hormone-inducible Xbra
Development, January 6, 1997; 124(11): 2225 - 2234.
[Abstract] [PDF]

J.C. Smith, N.A. Armes, F.L. Conlon, M. Tada, M. Umbhauer, and K.M. Weston
Upstream and Downstream from Brachyury, a Gene Required for Vertebrate Mesoderm Formation
Cold Spring Harb Symp Quant Biol, January 1, 1997; 62(0): 337 - 346.
[Abstract] [PDF]

N. Oellers and E. Hafen
Biochemical Characterization of RolledSem, an Activated Form of Drosophila Mitogen-activated Protein Kinase
J. Biol. Chem., October 4, 1996; 271(40): 24939 - 24944.
[Abstract] [Full Text] [PDF]

M. Fukuda, I. Gotoh, Y. Gotoh, and E. Nishida
Cytoplasmic Localization of Mitogen-activated Protein Kinase Kinase Directed by Its NH2-terminal, Leucine-rich Short Amino Acid Sequence, Which Acts as a Nuclear Export Signal
J. Biol. Chem., August 16, 1996; 271(33): 20024 - 20028.
[Abstract] [Full Text] [PDF]

Z. Dong, R.-H. Xu, J. Kim, S.-N. Zhan, W.-Y. Ma, N. H. Colburn, and H.-f. Kung
AP-1/Jun Is Required for Early Xenopus Development and Mediates Mesoderm Induction by Fibroblast Growth Factor but Not by Activin
J. Biol. Chem., April 26, 1996; 271(17): 9942 - 9946.
[Abstract] [Full Text] [PDF]

F. Conlon, S. Sedgwick, K. Weston, and J. Smith
Inhibition of Xbra transcription activation causes defects in mesodermal patterning and reveals autoregulation of Xbra in dorsal mesoderm
Development, January 8, 1996; 122(8): 2427 - 2435.
[Abstract] [PDF]

H Weber, B Holewa, E. Jones, and G. Ryffel
Mesoderm and endoderm differentiation in animal cap explants: identification of the HNF4-binding site as an activin A responsive element in the Xenopus HNF1alpha promoter
Development, January 6, 1996; 122(6): 1975 - 1984.
[Abstract] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by LaBonne, C.

Articles by Whitman, M.

Search for Related Content

PubMed

PubMed Citation

Articles by LaBonne, C.

Articles by Whitman, M.

Social Bookmarking

What's this?

				M. Cordenonsi, M. Montagner, M. Adorno, L. Zacchigna, G. Martello, A. Mamidi, S. Soligo, S. Dupont, and S. Piccolo Integration of TGF-{beta} and Ras/MAPK Signaling Through p53 Phosphorylation Science, February 9, 2007; 315(5813): 840 - 843. [Abstract] [Full Text] [PDF]

				R. T. Bottcher and C. Niehrs Fibroblast Growth Factor Signaling during Early Vertebrate Development Endocr. Rev., February 1, 2005; 26(1): 63 - 77. [Abstract] [Full Text] [PDF]

				A. P. Myers, L. B. Corson, J. Rossant, and J. C. Baker Characterization of Mouse Rsk4 as an Inhibitor of Fibroblast Growth Factor-RAS-Extracellular Signal-Regulated Kinase Signaling Mol. Cell. Biol., May 15, 2004; 24(10): 4255 - 4266. [Abstract] [Full Text] [PDF]

				J. Mathieu, K. Griffin, P. Herbomel, T. Dickmeis, U. Strahle, D. Kimelman, F. M. Rosa, and N. Peyrieras Nodal and Fgf pathways interact through a positive regulatory loop and synergize to maintain mesodermal cell populations Development, February 1, 2004; 131(3): 629 - 641. [Abstract] [Full Text] [PDF]

				L. B. Corson, Y. Yamanaka, K.-M. V. Lai, and J. Rossant Spatial and temporal patterns of ERK signaling during mouse embryogenesis Development, October 1, 2003; 130(19): 4527 - 4537. [Abstract] [Full Text] [PDF]

				K. Kawachi, N. Masuyama, and E. Nishida Essential Role of the Transcription Factor Ets-2 in Xenopus Early Development J. Biol. Chem., February 7, 2003; 278(7): 5473 - 5477. [Abstract] [Full Text] [PDF]

				M. Funaba, C. M. Zimmerman, and L. S. Mathews Modulation of Smad2-mediated Signaling by Extracellular Signal-regulated Kinase J. Biol. Chem., October 25, 2002; 277(44): 41361 - 41368. [Abstract] [Full Text] [PDF]

				K. Mood, R. Friesel, and I. O. Daar SNT1/FRS2 Mediates Germinal Vesicle Breakdown Induced by an Activated FGF Receptor1 in Xenopus Oocytes J. Biol. Chem., August 30, 2002; 277(36): 33196 - 33204. [Abstract] [Full Text] [PDF]

				E. K. Park, N. Warner, K. Mood, T. Pawson, and I. O. Daar Low-Molecular-Weight Protein Tyrosine Phosphatase Is a Positive Component of the Fibroblast Growth Factor Receptor Signaling Pathway Mol. Cell. Biol., May 15, 2002; 22(10): 3404 - 3414. [Abstract] [Full Text] [PDF]

				R. D. del Corral, D. N. Breitkreuz, and K. G. Storey Onset of neuronal differentiation is regulated by paraxial mesoderm and requires attenuation of FGF signalling Development, January 4, 2002; 129(7): 1681 - 1691. [Abstract] [Full Text] [PDF]

				J. A. Greenwald, B. J. Mehrara, J. A. Spector, S. M. Warren, P. J. Fagenholz, L. P. Smith, P. J. Bouletreau, F. E. Crisera, H. Ueno, and M. T. Longaker In Vivo Modulation of FGF Biological Activity Alters Cranial Suture Fate Am. J. Pathol., February 1, 2001; 158(2): 441 - 452. [Abstract] [Full Text] [PDF]

				A Abrieu, M Doree, and D Fisher The interplay between cyclin-B-Cdc2 kinase (MPF) and MAP kinase during maturation of oocytes J. Cell Sci., January 1, 2001; 114(2): 257 - 267. [Abstract] [PDF]

				R Carballada, H Yasuo, and P Lemaire Phosphatidylinositol-3 kinase acts in parallel to the ERK MAP kinase in the FGF pathway during Xenopus mesoderm induction Development, January 1, 2001; 128(1): 35 - 44. [Abstract] [PDF]

				M Umbhauer, A Penzo-Mendez, L Clavilier, J Boucaut, and J Riou Signaling specificities of fibroblast growth factor receptors in early Xenopus embryo J. Cell Sci., January 8, 2000; 113(16): 2865 - 2875. [Abstract] [PDF]

				W Lerchner, B. Latinkic, J. Remacle, D Huylebroeck, and J. Smith Region-specific activation of the Xenopus brachyury promoter involves active repression in ectoderm and endoderm: a study using transgenic frog embryos Development, January 6, 2000; 127(12): 2729 - 2739. [Abstract] [PDF]

				A. M. O'Reilly, S. Pluskey, S. E. Shoelson, and B. G. Neel Activated Mutants of SHP-2 Preferentially Induce Elongation of Xenopus Animal Caps Mol. Cell. Biol., January 1, 2000; 20(1): 299 - 311. [Abstract] [Full Text]

				I. Gotoh, M. Fukuda, M. Adachi, and E. Nishida Control of the Cell Morphology and the S Phase Entry by Mitogen-activated Protein Kinase Kinase. A REGULATORY ROLE OF ITS N-TERMINAL REGION J. Biol. Chem., April 23, 1999; 274(17): 11874 - 11880. [Abstract] [Full Text] [PDF]

				M. Wagner, P. Briza, M. Pierce, and E. Winter Distinct Steps in Yeast Spore Morphogenesis Require Distinct SMK1 MAP Kinase Thresholds Genetics, April 1, 1999; 151(4): 1327 - 1340. [Abstract] [Full Text]

				K Wunnenberg-Stapleton, I. Blitz, C Hashimoto, and K. Cho Involvement of the small GTPases XRhoA and XRnd1 in cell adhesion and head formation in early Xenopus development Development, January 12, 1999; 126(23): 5339 - 5351. [Abstract] [PDF]

				M Watanabe and M Whitman FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo Development, January 12, 1999; 126(24): 5621 - 5634. [Abstract] [PDF]

				B Christen and J. Slack Spatial response to fibroblast growth factor signalling in Xenopus embryos Development, January 1, 1999; 126(1): 119 - 125. [Abstract] [PDF]

				A. R. Uzgare, J. A. Uzman, H. M. El-Hodiri, and A. K. Sater Mitogen-activated protein kinase and neural specification in Xenopus PNAS, December 8, 1998; 95(25): 14833 - 14838. [Abstract] [Full Text] [PDF]

				A. Michelson, S Gisselbrecht, E Buff, and J. Skeath Heartbroken is a specific downstream mediator of FGF receptor signalling in Drosophila Development, January 11, 1998; 125(22): 4379 - 4389. [Abstract] [PDF]

				E. Casey, M. O'Reilly, F. Conlon, and J. Smith The T-box transcription factor Brachyury regulates expression of eFGF through binding to a non-palindromic response element Development, January 10, 1998; 125(19): 3887 - 3894. [Abstract] [PDF]

				M. Fukuda, I. Gotoh, M. Adachi, Y. Gotoh, and E. Nishida A Novel Regulatory Mechanism in the Mitogen-activated Protein (MAP) Kinase Cascade. ROLE OF NUCLEAR EXPORT SIGNAL OF MAP KINASE KINASE J. Biol. Chem., December 19, 1997; 272(51): 32642 - 32648. [Abstract] [Full Text] [PDF]

				R. E. Schweppe, A. A. Frazer-Abel, A. Gutierrez-Hartmann, and A. P. Bradford Functional Components of Fibroblast Growth Factor (FGF) Signal Transduction in Pituitary Cells. IDENTIFICATION OF FGF RESPONSE ELEMENTS IN THE PROLACTIN GENE J. Biol. Chem., December 5, 1997; 272(49): 30852 - 30859. [Abstract] [Full Text] [PDF]

				R.-H. Xu, J. Kim, M. Taira, D. Sredni, and H.-f. Kung Studies on the Role of Fibroblast Growth Factor Signaling in Neurogenesis Using Conjugated/Aged Animal Caps and Dorsal Ectoderm-Grafted Embryos J. Neurosci., September 15, 1997; 17(18): 6892 - 6898. [Abstract] [Full Text] [PDF]

				K. Takenaka, Y. Gotoh, and E. Nishida MAP Kinase Is Required for the Spindle Assembly Checkpoint but Is Dispensable for the Normal M Phase Entry and Exit in Xenopus Egg Cell Cycle Extracts J. Cell Biol., March 10, 1997; 136(5): 1091 - 1097. [Abstract] [Full Text] [PDF]

				M Tada, M. O'Reilly, and J. Smith Analysis of competence and of Brachyury autoinduction by use of hormone-inducible Xbra Development, January 6, 1997; 124(11): 2225 - 2234. [Abstract] [PDF]

				J.C. Smith, N.A. Armes, F.L. Conlon, M. Tada, M. Umbhauer, and K.M. Weston Upstream and Downstream from Brachyury, a Gene Required for Vertebrate Mesoderm Formation Cold Spring Harb Symp Quant Biol, January 1, 1997; 62(0): 337 - 346. [Abstract] [PDF]