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G. T. Wong, D. Manfra, F. M. Poulet, Q. Zhang, H. Josien, T. Bara, L. Engstrom, M. Pinzon-Ortiz, J. S. Fine, H.-J. J. Lee, et al. Chronic Treatment with the {gamma}-Secretase Inhibitor LY-411,575 Inhibits {beta}-Amyloid Peptide Production and Alters Lymphopoiesis and Intestinal Cell Differentiation J. Biol. Chem., March 26, 2004; 279(13): 12876 - 12882. [Abstract] [Full Text] [PDF] |
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R. Cordes, K. Schuster-Gossler, K. Serth, and A. Gossler Specification of vertebral identity is coupled to Notch signalling and the segmentation clock Development, March 15, 2004; 131(6): 1221 - 1233. [Abstract] [Full Text] [PDF] |
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H. Qin, J. Wang, Y. Liang, Y. Taniguchi, K. Tanigaki, and H. Han RING1 inhibits transactivation of RBP-J by Notch through interaction with LIM protein KyoT2 Nucleic Acids Res., March 3, 2004; 32(4): 1492 - 1501. [Abstract] [Full Text] [PDF] |
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L. A. Timmerman, J. Grego-Bessa, A. Raya, E. Bertran, J. M. Perez-Pomares, J. Diez, S. Aranda, S. Palomo, F. McCormick, J. C. Izpisua-Belmonte, et al. Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation Genes & Dev., January 1, 2004; 18(1): 99 - 115. [Abstract] [Full Text] [PDF] |
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C. Dahlqvist, A. Blokzijl, G. Chapman, A. Falk, K. Dannaeus, C. F. Ibanez, and U. Lendahl Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation Development, December 15, 2003; 130(24): 6089 - 6099. [Abstract] [Full Text] [PDF] |
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P. Cheng, Y. Nefedova, L. Miele, B. A. Osborne, and D. Gabrilovich Notch signaling is necessary but not sufficient for differentiation of dendritic cells Blood, December 1, 2003; 102(12): 3980 - 3988. [Abstract] [Full Text] [PDF] |
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H.-T. Cheng, J. H. Miner, M. Lin, M. G. Tansey, K. Roth, and R. Kopan {gamma}-Secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney Development, October 15, 2003; 130(20): 5031 - 5042. [Abstract] [Full Text] [PDF] |
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P. Wang, F. A. Pereira, D. Beasley, and H. Zheng Presenilins are required for the formation of comma- and S-shaped bodies during nephrogenesis Development, October 15, 2003; 130(20): 5019 - 5029. [Abstract] [Full Text] [PDF] |
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B. S. Mankoo, S. Skuntz, I. Harrigan, E. Grigorieva, A. Candia, C. V. E. Wright, H. Arnheiter, and V. Pachnis The concerted action of Meox homeobox genes is required upstream of genetic pathways essential for the formation, patterning and differentiation of somites Development, October 1, 2003; 130(19): 4655 - 4664. [Abstract] [Full Text] [PDF] |
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Y. Takahashi, T. Inoue, A. Gossler, and Y. Saga Feedback loops comprising Dll1, Dll3 and Mesp2, and differential involvement of Psen1 are essential for rostrocaudal patterning of somites Development, September 15, 2003; 130(18): 4259 - 4268. [Abstract] [Full Text] [PDF] |
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J. Li, G. J. Fici, C.-A. Mao, R. L. Myers, R. Shuang, G. P. Donoho, A. M. Pauley, C. S. Himes, W. Qin, I. Kola, et al. Positive and Negative Regulation of the {gamma}-Secretase Activity by Nicastrin in a Murine Model J. Biol. Chem., August 29, 2003; 278(35): 33445 - 33449. [Abstract] [Full Text] [PDF] |
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B. D. Crawford, C. A. Henry, T. A. Clason, A. L. Becker, and M. B. Hille Activity and Distribution of Paxillin, Focal Adhesion Kinase, and Cadherin Indicate Cooperative Roles during Zebrafish Morphogenesis Mol. Biol. Cell, August 1, 2003; 14(8): 3065 - 3081. [Abstract] [Full Text] [PDF] |
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F. Gofflot, C. Hars, F. Illien, F. Chevy, C. Wolf, J. J. Picard, and C. Roux Molecular mechanisms underlying limb anomalies associated with cholesterol deficiency during gestation: implications of Hedgehog signaling Hum. Mol. Genet., May 15, 2003; 12(10): 1187 - 1198. [Abstract] [Full Text] [PDF] |
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S. Shi and P. Stanley Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways PNAS, April 29, 2003; 100(9): 5234 - 5239. [Abstract] [Full Text] [PDF] |
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D. Small, D. Kovalenko, R. Soldi, A. Mandinova, V. Kolev, R. Trifonova, C. Bagala, D. Kacer, C. Battelli, L. Liaw, et al. Notch Activation Suppresses Fibroblast Growth Factor-dependent Cellular Transformation J. Biol. Chem., April 25, 2003; 278(18): 16405 - 16413. [Abstract] [Full Text] [PDF] |
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T. Li, G. Ma, H. Cai, D. L. Price, and P. C. Wong Nicastrin Is Required for Assembly of Presenilin/gamma -Secretase Complexes to Mediate Notch Signaling and for Processing and Trafficking of beta -Amyloid Precursor Protein in Mammals J. Neurosci., April 15, 2003; 23(8): 3272 - 3277. [Abstract] [Full Text] [PDF] |
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K. Serth, K. Schuster-Gossler, R. Cordes, and A. Gossler Transcriptional oscillation of Lunatic fringe is essential for somitogenesis Genes & Dev., April 1, 2003; 17(7): 912 - 925. [Abstract] [Full Text] [PDF] |
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T. Schroeder, S. T. Fraser, M. Ogawa, S. Nishikawa, C. Oka, G. W. Bornkamm, S.-I. Nishikawa, T. Honjo, and U. Just Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis PNAS, April 1, 2003; 100(7): 4018 - 4023. [Abstract] [Full Text] [PDF] |
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N. S. Hamblet, N. Lijam, P. Ruiz-Lozano, J. Wang, Y. Yang, Z. Luo, L. Mei, K. R. Chien, D. J. Sussman, and A. Wynshaw-Boris Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure Development, March 14, 2003; 129(24): 5827 - 5838. [Abstract] [Full Text] [PDF] |
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S. Hans and J. A. Campos-Ortega On the organisation of the regulatory region of the zebrafish deltaD gene Development, March 12, 2003; 129(20): 4773 - 4784. [Abstract] [Full Text] [PDF] |
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A. C. Oates and R. K. Ho Hairy/E(spl)-related (Her) genes are central components of the segmentation oscillator and display redundancy with the Delta/Notch signaling pathway in the formation of anterior segmental boundaries in the zebrafish Development, March 8, 2003; 129(12): 2929 - 2946. [Abstract] [Full Text] [PDF] |
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S. Lutolf, F. Radtke, M. Aguet, U. Suter, and V. Taylor Notch1 is required for neuronal and glial differentiation in the cerebellum Development, March 3, 2003; 129(2): 373 - 385. [Abstract] [Full Text] [PDF] |
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H. Karlstrom, P. Beatus, K. Dannaeus, G. Chapman, U. Lendahl, and J. Lundkvist A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling PNAS, December 24, 2002; 99(26): 17119 - 17124. [Abstract] [Full Text] [PDF] |
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S.-E. Lin, T. Oyama, T. Nagase, K. Harigaya, and M. Kitagawa Identification of New Human Mastermind Proteins Defines a Family That Consists of Positive Regulators for Notch Signaling J. Biol. Chem., December 20, 2002; 277(52): 50612 - 50620. [Abstract] [Full Text] [PDF] |
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A. H. Campos, W. Wang, M. J. Pollman, and G. H. Gibbons Determinants of Notch-3 Receptor Expression and Signaling in Vascular Smooth Muscle Cells: Implications in Cell-Cycle Regulation Circ. Res., November 29, 2002; 91(11): 999 - 1006. [Abstract] [Full Text] [PDF] |
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R. Rozmahel, H. T. J. Mount, F. Chen, V. Nguyen, J. Huang, S. Erdebil, J. Liauw, G. Yu, H. Hasegawa, Y. Gu, et al. Alleles at the Nicastrin locus modify presenilin 1- deficiency phenotype PNAS, October 29, 2002; 99(22): 14452 - 14457. [Abstract] [Full Text] [PDF] |
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L. A. Hanna, R. K. Foreman, I. A. Tarasenko, D. S. Kessler, and P. A. Labosky Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo Genes & Dev., October 15, 2002; 16(20): 2650 - 2661. [Abstract] [Full Text] [PDF] |
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S. Genoud, C. Lappe-Siefke, S. Goebbels, F. Radtke, M. Aguet, S. S. Scherer, U. Suter, K.-A. Nave, and N. Mantei Notch1 control of oligodendrocyte differentiation in the spinal cord J. Cell Biol., August 19, 2002; 158(4): 709 - 718. [Abstract] [Full Text] [PDF] |
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Y. Sato, K. Yasuda, and Y. Takahashi Morphological boundary forms by a novel inductive event mediated by Lunatic fringe and Notch during somitic segmentation Development, August 1, 2002; 129(15): 3633 - 3644. [Abstract] [Full Text] [PDF] |
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C. A. Henry, M. K. Urban, K. K. Dill, J. P. Merlie, M. F. Page, C. B. Kimmel, and S. L. Amacher Two linked hairy/Enhancer of split-related zebrafish genes, her1 and her7, function together to refine alternating somite boundaries Development, August 1, 2002; 129(15): 3693 - 3704. [Abstract] [Full Text] [PDF] |
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W. Wang, A. H. Campos, C. Z. Prince, Y. Mou, and M. J. Pollman Coordinate Notch3-Hairy-related Transcription Factor Pathway Regulation in Response to Arterial Injury. MEDIATOR ROLE OF PLATELET-DERIVED GROWTH FACTOR AND ERK J. Biol. Chem., June 21, 2002; 277(26): 23165 - 23171. [Abstract] [Full Text] [PDF] |
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W. Wang, C. Z. Prince, Y. Mou, and M. J. Pollman Notch3 Signaling in Vascular Smooth Muscle Cells Induces c-FLIP Expression via ERK/MAPK Activation. RESISTANCE TO Fas LIGAND-INDUCED APOPTOSIS J. Biol. Chem., June 7, 2002; 277(24): 21723 - 21729. [Abstract] [Full Text] [PDF] |
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H. Han, K. Tanigaki, N. Yamamoto, K. Kuroda, M. Yoshimoto, T. Nakahata, K. Ikuta, and T. Honjo Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision Int. Immunol., June 1, 2002; 14(6): 637 - 645. [Abstract] [Full Text] [PDF] |
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J. Bose, L. Grotewold, and U. Ruther Pallister-Hall syndrome phenotype in mice mutant for Gli3 Hum. Mol. Genet., May 1, 2002; 11(9): 1129 - 1135. [Abstract] [Full Text] [PDF] |
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S. Hitoshi, T. Alexson, V. Tropepe, D. Donoviel, A. J. Elia, J. S. Nye, R. A. Conlon, T. W. Mak, A. Bernstein, and D. van der Kooy Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells Genes & Dev., April 1, 2002; 16(7): 846 - 858. [Abstract] [Full Text] [PDF] |
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B. E. Berechid, M. Kitzmann, D. R. Foltz, A. H. Roach, D. Seiffert, L. A. Thompson, R. E. Olson, A. Bernstein, D. B. Donoviel, and J. S. Nye Identification and Characterization of Presenilin-independent Notch Signaling J. Biol. Chem., March 1, 2002; 277(10): 8154 - 8165. [Abstract] [Full Text] [PDF] |
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S Lovestone and D M McLoughlin Protein aggregates and dementia: is there a common toxicity? J. Neurol. Neurosurg. Psychiatry, February 1, 2002; 72(2): 152 - 161. [Abstract] [Full Text] [PDF] |
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J.L. Stanton and D.P.L. Green A set of 1542 mouse blastocyst and pre-blastocyst genes with well-matched human homologues Mol. Hum. Reprod., February 1, 2002; 8(2): 149 - 166. [Abstract] [Full Text] [PDF] |
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R. M. Anderson, A. R. Lawrence, R. W. Stottmann, D. Bachiller, and J. Klingensmith Chordin and noggin promote organizing centers of forebrain development in the mouse Development, January 11, 2002; 129(21): 4975 - 4987. [Abstract] [Full Text] [PDF] |
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S. L. Dunwoodie, M. Clements, D. B. Sparrow, X. Sa, R. A. Conlon, and R. S. P. Beddington Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm Development, January 4, 2002; 129(7): 1795 - 1806. [Abstract] [Full Text] [PDF] |
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S. A. Holley, D. Julich, G.-J. Rauch, R. Geisler, and C. Nusslein-Volhard her1 and the notch pathway function within the oscillator mechanism that regulates zebrafish somitogenesis Development, January 3, 2002; 129(5): 1175 - 1183. [Abstract] [Full Text] [PDF] |
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O. Voiculescu, E. Taillebourg, C. Pujades, C. Kress, S. Buart, P. Charnay, and S. Schneider-Maunoury Hindbrain patterning: Krox20 couples segmentation and specification of regional identity Development, December 15, 2001; 128(24): 4967 - 4978. [Abstract] [Full Text] [PDF] |
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