Induction of dorsal mesoderm by soluble, mature Vg1 protein

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Kessler, D. S.
	Articles by Melton, D. A.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Kessler, D. S.
	Articles by Melton, D. A.

Amaya, E., Musci, T. J. and Kirschner, M. W (1991). Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in Xenopus embryos. Cell 66, 257-270.[Medline]

Asashima, M., Nakano, H., Uchiyama, H., Sugino, H., Nakamura, T., Eto, Y., Ejima, D., Nishimatsu, S. I., Ueno, N. and Kinoshita, K (1991). Presence of activin (erythroid differentiation factor) in unfertilized eggs and blastulae of Xenopus laevis. Proc. Natl. Acad. Sci. USA 88, 6511-6514.[Abstract/Free Full Text]

Blumberg, B., Wright, C. V., De Robertis, E. M. and Cho, K. W (1991). Organizer-specific homeobox genes in Xenopus laevis embryos. Science 253, 194-196.[Abstract/Free Full Text]

Christian, J. L., McMahon, J. A., McMahon, A. P. and Moon, R. T (1991). Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm inducing factors may play a role in ventral mesodermal patterning during embryogenesis. Development 111, 1045-1056.[Abstract/Free Full Text]

Cornell, R. and Kimelman, D (1994). Activin-mediated mesoderm induction requires FGF. Development 120, 453-462.[Abstract]

Dale, L. and Slack, J. M. W (1987). Regional specification within the mesoderm of early embryos of Xenopus laevis. Development 100, 279-295.[Abstract/Free Full Text]

Dale, L., Matthews, G., Tabe, L. and Colman, A (1989). Developmental expression of the protein product of Vg1, a localized maternal mRNA in the frog Xenopus laevis. EMBO J 8, 1057-1065.[Medline]

Dale, L., Matthews, G. and Colman, A (1993). Secretion and mesoderm-inducing activity of the TGF- -related domain of Xenopus Vg1. EMBO J 12, 4471-4480.[Medline]

Elinson, R. P. and Rowning, B (1988). A transient array of parallel microtubules in frog eggs: potential tracks for a cytoplasmic rotation that specifies the dorso-ventral axis. Dev. Biol 128, 185-97.[Medline]

Elinson, R. P. and Kao, K. R (1989). The location of dorsal information in frog early development. Dev. Growth Diff 31, 423-430.

Evan, G. I., Lewis, G. K., Ramsay, G. and Bishop, J. M (1985). Isolation of monoclonal antibodies specific for human c- myc protooncogene product. Mol. Cell Biol 5, 3610-3616.[Abstract/Free Full Text]

Fukui, A., Nakamura, T., Sugino, K., Takio, K., Uchiyama, H., Asashima, M. and Sugino, H (1993). Isolation and characterization of Xenopus follistatin and activin. Dev. Biol 159, 131-139.[Medline]

Fukui, A., Nakamura, T., Uchiyama, H., Sugino, K., Sugino, H. and Asashima, M (1994). Identification of activins A, AB, and B and follistatin proteins in Xenopus embryos. Dev. Biol 163, 279-281.[Medline]

Gerhart, J., Danilchik, M., Doniach, T., Roberts, S., Rowning, B. and Stewart, R (1989). Cortical rotation of the Xenopus egg: consequences for the anteroposterior pattern of embryonic dorsal development. Development 107, 37-51.

Gimlich, R. L. and Gerhart, J. C (1984). Early cellular interactions promote embryonic axis formation in Xenopus laevis. Dev. Biol 104, 117-130.[Medline]

Graff, J. M., Thies, R. S., Song, J. J., Celeste, A. J. and Melton, D. A (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.[Medline]

Gray, A. M. and Mason, A. J (1990). Requirement for activin A and transforming growth factor-1 pro-regions in homodimer assembly. Science 247, 1328-1330.[Abstract/Free Full Text]

Hemmati-Brivanlou, A., Kelly, O. G. and Melton, D. A (1994). Follistatin, an antagonist of activin, is present in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295.[Medline]

Hemmati-Brivanlou, A. and Melton, D. A (1992). A truncated activin receptor dominantly inhibits mesoderm induction and formation of axial structures in Xenopus embryos. Nature 359, 609-614.[Medline]

Jones, E. A. and Woodland, H. R (1987). The development of animal cap cells in Xenopus : a measure of the start of animal cap competence to form mesoderm. Development 101, 557-563.[Abstract]

Kageura, H (1990). Spatial distribution of the capacity to initiate a secondary embryo in the 32-cell embryo of Xenopus laevis. Dev. Biol 142, 432-8.[Medline]

Kessler, D. S. and Melton, D. A (1994). Vertebrate embryonic induction: mesodermal and neural patterning. Science 266, 596-604.[Abstract/Free Full Text]

Kintner, C. R. and Melton, D. A (1987). Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction. Development 99, 311-325.[Abstract]

Kogawa, K., Nakamura, T., Sugino, K., Takio, K., Titani, K. and Sugino, H (1991). Activin-binding protein is present in pituitary. Endocrinology 128, 1434-1440.[Abstract]

Krieg, P., Varnum, S., Wormington, M. and Melton, D. A (1989). The mRNA encoding elongation factor 1(EF1 ) is a major transcript at the mid-blastula transition in Xenopus. Dev. Biol 133, 93-100.[Medline]

Krieg, P. A. and Melton, D. A (1987). In vitro RNA synthesis with SP6 RNA polymerase. Meth. Enzymol 155, 397-415.[Medline]

LaBonne, C. and Whitman, M (1994). Mesoderm induction by activin requires FGF-mediated intracellular signals. Development 120, 463-472.[Abstract]

Melton, D. A (1987). Translocation of a localized maternal mRNA to the vegetal pole of Xenopus oocytes. Nature 328, 80-82.[Medline]

Mowry, K. and Melton, D (1992). Vegetal messenger RNA localization directed by a 340-nt sequence element in Xenopus oocytes. Science 255, 991-994.[Abstract/Free Full Text]

Nakamura, T., Takio, K., Eto, Y., Shibai, H., Titani, K. and Sugino, H (1990). Activin-binding protein from rat ovary is follistatin. Science 247, 836-838.[Abstract/Free Full Text]

Nishimatsu, S., Takebayashi, K., Suzuki, A., Murakami, K. and Ueno, N (1993). Immunodetection of Xenopus bone morphogenetic protein-4 in early embryos. Growth Factors 8, 173-6.[Medline]

Rebagliati, M. R., Weeks, D. L., Harvey, R. P. and Melton, D. A (1985). Identification and cloning of localized maternal mRNAs from Xenopus eggs. Cell 42, 769-777.[Medline]

Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. and De Robertis, E. M (1994). Xenopus chordin: a novel drosalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.[Medline]

Schulte-Merker, S., Smith, J. C. and Dale, L (1994). Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction?. EMBO J 13, 3533-3541.[Medline]

Slack, J. M. W (1991). The nature of the mesoderm-inducing signal in Xenopus : a transfilter induction study. Development 113, 661-669.[Abstract]

Slack, J. M. W. and Foreman, D (1980). An interaction between dorsal and ventral regions of the marginal zone in early amphibian embryos. J. Embryol. Exp. Morph 56, 283-299.[Medline]

Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. and Herrmann, B. G (1991). Expression of a Xenopus homolog of Brachyury (T) in an immediate-early response to mesoderm induction. Cell 67, 79-87.[Medline]

Smith, W. C. and Harland, R. M (1991). Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center. Cell 67, 753-765.[Medline]

Smith, W. C. and Harland, R. M (1992). Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70, 829-840.[Medline]

Smith, W. C., Knecht, A. K., Wu, M. and Harland, R.M (1993). Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature 361, 547-549.[Medline]

Sokol, S., Wong, G. G. and Melton, D. A (1990). A mouse macrophage factor induces head structures and organizes a body axis in Xenopus. Science 249, 561-564.[Abstract/Free Full Text]

Sokol, S., Christian, J. L., Moon, R. T. and Melton, D. A (1991). Injected wnt RNA induces a complete body axis in Xenopus embryos. Cell 67, 741-752.[Medline]

Stutz, F. and Sphor, G (1986). Isolation and characterization of sarcomeric actin genes expressed in Xenopus laevis embryos. J. Mol. Biol 187, 349-361.[Medline]

Suzuki, A., Thies, R. S., Yamaji, N., Song, J. J., Wozney, J. M., Murakami, K. and Ueno, N (1994). A truncated BMP receptor affects dorsal-ventral patterning in the early Xenopus embryo. Proc. Natl. Acad. Sci. U.S.A 91, 10255-10259.[Abstract/Free Full Text]

Symes, K. and Smith, J. C (1987). Gastrulation movements provide an early marker of mesoderm induction in Xenopus laevis. Development 101, 339-349.[Abstract]

Tannahill, D. and Melton, D. A (1989). Localized synthesis of the Vg1 protein during early Xenopus development. Development 106, 775-785.[Abstract/Free Full Text]

Tashiro, K., Yamada, R., Asano, M., Hasimoto, M., Muramatsu, M. and Shiokawa, K (1991). Expression of mRNA for activin-binding protein (follistatin) during early embryonic development of Xenopus laevis. Biochem. Biophy. Res. Comm 174, 1022-1027.[Medline]

Thomsen, G., Woolf, T., Whitman, M., Sokol, S., Vaughan, J., Vale, W. and Melton, D. A (1990). Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell 63, 485-493.[Medline]

Thomsen, G. H. and Melton, D. A (1993). Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell 74, 433-41.[Medline]

Ueno, N., Shoda, A., Takebayashi, K., Suzuki, A., Nishimatsu, S-I., Kikuchi, T., Wakimasu, M., Fujino, M. and Murakami, K (1992). Identification of bone morphogenetic protein-2 in early Xenopus laevis embryos. Growth Factors 7, 233-240.[Medline]

Vincent, J.-P. and Gerhart, J. C (1987). Subcortical rotation in Xenopus eggs: an early step in embryonic axis specification. Dev. Biol 123, 526-539.[Medline]

Vize, P. D. and Thomsen, G. H (1994). Vg1 and regional specification in vertebrates: a new role for an old molecule. Trends Genet 10, 371-376.[Medline]

Weeks, D. L. and Melton, D. A (1987). A maternal mRNA localized to the vegetal hemisphere in Xenopus eggs codes for a growth factor related to TGF-. Cell 51, 861-867.[Medline]

Wilson, P. A. and Melton, D. A (1994). Mesodermal patterning by an inducer gradient depends on secondary cell-cell communication. Curr. Biol 4, 676-686.[Medline]

Yamada, T (1950). Regional differentiation of the isolated ectoderm of the Triturus gastrula induced through a protein extract. Embryologia 1, 1-20.

Yisraeli, J. and Melton, D. A (1988). The maternal mRNA Vg1 is correctly localized following injection into Xenopus oocytes. Nature 336, 592-595.[Medline]

This article has been cited by other articles:

C. Tanaka, R. Sakuma, T. Nakamura, H. Hamada, and Y. Saijoh
Long-range action of Nodal requires interaction with GDF1
Genes & Dev., December 15, 2007; 21(24): 3272 - 3282.
[Abstract] [Full Text] [PDF]

Y. Kurotaki, K. Hatta, K. Nakao, Y.-i. Nabeshima, and T. Fujimori
Blastocyst Axis Is Specified Independently of Early Cell Lineage But Aligns with the ZP Shape
Science, May 4, 2007; 316(5825): 719 - 723.
[Abstract] [Full Text] [PDF]

S. Sopory, S. M. Nelsen, C. Degnin, C. Wong, and J. L. Christian
Regulation of Bone Morphogenetic Protein-4 Activity by Sequence Elements within the Prodomain
J. Biol. Chem., November 10, 2006; 281(45): 34021 - 34031.
[Abstract] [Full Text] [PDF]

K. CZAPLINSKI and I. W. MATTAJ
40LoVe interacts with Vg1RBP/Vera and hnRNP I in binding the Vg1-Localization Element
RNA, February 1, 2006; 12(2): 213 - 222.
[Abstract] [Full Text] [PDF]

C. Chen, S. M. Ware, A. Sato, D. E. Houston-Hawkins, R. Habas, M. M. Matzuk, M. M. Shen, and C. W. Brown
The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo
Development, January 15, 2006; 133(2): 319 - 329.
[Abstract] [Full Text] [PDF]

B. Birsoy, M. Kofron, K. Schaible, C. Wylie, and J. Heasman
Vg1 is an essential signaling molecule in Xenopus development
Development, January 1, 2006; 133(1): 15 - 20.
[Abstract] [Full Text] [PDF]

M. Kloc, K. Wilk, D. Vargas, Y. Shirato, S. Bilinski, and L. D. Etkin
Potential structural role of non-coding and coding RNAs in the organization of the cytoskeleton at the vegetal cortex of Xenopus oocytes
Development, August 1, 2005; 132(15): 3445 - 3457.
[Abstract] [Full Text] [PDF]

B. Birsoy, L. Berg, P. H. Williams, J. C. Smith, C. C. Wylie, J. L. Christian, and J. Heasman
XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGF{beta} proteins in Xenopus development
Development, February 1, 2005; 132(3): 591 - 602.
[Abstract] [Full Text] [PDF]

T. L. Kress, Y. J. Yoon, and K. L. Mowry
Nuclear RNP complex assembly initiates cytoplasmic RNA localization
J. Cell Biol., April 26, 2004; 165(2): 203 - 211.
[Abstract] [Full Text] [PDF]

S. K. Cheng, F. Olale, J. T. Bennett, A. H. Brivanlou, and A. F. Schier
EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1
Genes & Dev., January 1, 2003; 17(1): 31 - 36.
[Abstract] [Full Text] [PDF]

Y. Cui, R. Hackenmiller, L. Berg, F. Jean, T. Nakayama, G. Thomas, and J. L. Christian
The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor
Genes & Dev., November 1, 2001; 15(21): 2797 - 2802.
[Abstract] [Full Text] [PDF]

S Faure, M. Lee, T Keller, P ten Dijke, and M Whitman
Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development
Development, January 7, 2000; 127(13): 2917 - 2931.
[Abstract] [PDF]

R Vignali, L Poggi, F Madeddu, and G Barsacchi
HNF1(beta) is required for mesoderm induction in the Xenopus embryo
Development, January 4, 2000; 127(7): 1455 - 1465.
[Abstract] [PDF]

J. Aaltonen, M. P. Laitinen, K. Vuojolainen, R. Jaatinen, N. Horelli-Kuitunen, L. Seppä, H. Louhio, T. Tuuri, J. Sjöberg, R. Bützow, et al.
Human Growth Differentiation Factor 9 (GDF-9) and Its Novel Homolog GDF-9B Are Expressed in Oocytes during Early Folliculogenesis
J. Clin. Endocrinol. Metab., August 1, 1999; 84(8): 2744 - 2750.
[Abstract] [Full Text]

A. Ramsdell and H. Yost
Cardiac looping and the vertebrate left-right axis: antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway
Development, January 12, 1999; 126(23): 5195 - 5205.
[Abstract] [PDF]

M Watanabe and M Whitman
FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo
Development, January 12, 1999; 126(24): 5621 - 5634.
[Abstract] [PDF]

A. Chan, M Kloc, and L. Etkin
fatvg encodes a new localized RNA that uses a 25-nucleotide element (FVLE1) to localize to the vegetal cortex of Xenopus oocytes
Development, January 11, 1999; 126(22): 4943 - 4953.
[Abstract] [PDF]

C Chang and A Hemmati-Brivanlou
Xenopus GDF6, a new antagonist of noggin and a partner of BMPs
Development, January 8, 1999; 126(15): 3347 - 3357.
[Abstract] [PDF]

Z Gu, E. Reynolds, J Song, H Lei, A Feijen, L Yu, W He, D. MacLaughlin, J van den Eijnden-van Raaij, P. Donahoe, et al.
The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo
Development, January 6, 1999; 126(11): 2551 - 2561.
[Abstract] [PDF]

K Fekany, Y Yamanaka, T Leung, H. Sirotkin, J Topczewski, M. Gates, M Hibi, A Renucci, D Stemple, A Radbill, et al.
The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures
Development, January 4, 1999; 126(7): 1427 - 1438.
[Abstract] [PDF]

B. Sun, S. Bush, L. Collins-Racie, E. LaVallie, E. DiBlasio-Smith, N. Wolfman, J. McCoy, and H. Sive
derriere: a TGF-beta family member required for posterior development in Xenopus
Development, January 4, 1999; 126(7): 1467 - 1482.
[Abstract] [PDF]

D. Szüts, S. Eresh, and M. Bienz
Functional intertwining of Dpp and EGFR signaling during Drosophila endoderm�induction
Genes & Dev., July 1, 1998; 12(13): 2022 - 2035.
[Abstract] [Full Text]

Y. Yamane, R. Tohno-oka, S. Yamada, S. Furuya, K. Shiokawa, Y. Hirabayashi, H. Sugino, and K. Sugahara
Molecular Characterization of Xenopus Embryo Heparan Sulfate. DIFFERENTIAL STRUCTURAL REQUIREMENTS FOR THE SPECIFIC BINDING TO BASIC FIBROBLAST GROWTH FACTOR AND FOLLISTATIN
J. Biol. Chem., March 27, 1998; 273(13): 7375 - 7381.
[Abstract] [Full Text] [PDF]

E. Joseph and D. Melton
Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos
Development, January 7, 1998; 125(14): 2677 - 2685.
[Abstract] [PDF]

M. L. Rebbert and I. B. Dawid
Transcriptional regulation of the Xlim-1 gene by activin is mediated by an element in intron�I
PNAS, September 2, 1997; 94(18): 9717 - 9722.
[Abstract] [Full Text] [PDF]

D Gautreau, C. Cote, and K. Mowry
Two copies of a subelement from the Vg1 RNA localization sequence are sufficient to direct vegetal localization in Xenopus oocytes
Development, January 12, 1997; 124(24): 5013 - 5020.
[Abstract] [PDF]

S. Shah, I Skromne, C. Hume, D. Kessler, K. Lee, C. Stern, and J Dodd
Misexpression of chick Vg1 in the marginal zone induces primitive streak formation
Development, January 12, 1997; 124(24): 5127 - 5138.
[Abstract] [PDF]

A. Candia, T Watabe, S. Hawley, D Onichtchouk, Y Zhang, R Derynck, C Niehrs, and K. Cho
Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads
Development, January 11, 1997; 124(22): 4467 - 4480.
[Abstract] [PDF]

R Dosch, V Gawantka, H Delius, C Blumenstock, and C Niehrs
Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus
Development, January 6, 1997; 124(12): 2325 - 2334.
[Abstract] [PDF]

S. Witta and S. Sato
XIPOU 2 is a potential regulator of Spemann's Organizer
Development, January 3, 1997; 124(6): 1179 - 1189.
[Abstract] [PDF]

C Chang, P. Wilson, L. Mathews, and A Hemmati-Brivanlou
A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis
Development, January 2, 1997; 124(4): 827 - 837.
[Abstract] [PDF]

F Fagotto, K Guger, and B. Gumbiner
Induction of the primary dorsalizing center in Xenopus by the Wnt/GSK/beta-catenin signaling pathway, but not by Vg1, Activin or Noggin
Development, January 1, 1997; 124(2): 453 - 460.
[Abstract] [PDF]

S Hoppler, J D Brown, and R T Moon
Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos.
Genes & Dev., November 1, 1996; 10(21): 2805 - 2817.
[Abstract] [PDF]

M. Mullins, M Hammerschmidt, D. Kane, J Odenthal, M Brand, F. van Eeden, M Furutani-Seiki, M Granato, P Haffter, C. Heisenberg, et al.
Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes
Development, January 12, 1996; 123(1): 81 - 93.
[Abstract] [PDF]

M Hammerschmidt, F Pelegri, M. Mullins, D. Kane, F. van Eeden, M Granato, M Brand, M Furutani-Seiki, P Haffter, C. Heisenberg, et al.
dino and mercedes, two genes regulating dorsal development in the zebrafish embryo
Development, January 12, 1996; 123(1): 95 - 102.
[Abstract] [PDF]

J Zhang and M. King
Xenopus VegT RNA is localized to the vegetal cortex during oogenesis and encodes a novel T-box transcription factor involved in mesodermal patterning
Development, January 12, 1996; 122(12): 4119 - 4129.
[Abstract] [PDF]

F Stennard, G Carnac, and J. Gurdon
The Xenopus T-box gene, Antipodean, encodes a vegetally localised maternal mRNA and can trigger mesoderm formation
Development, January 12, 1996; 122(12): 4179 - 4188.
[Abstract] [PDF]

C. Jones, L Dale, B. Hogan, C. Wright, and J. Smith
Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos
Development, January 5, 1996; 122(5): 1545 - 1554.
[Abstract] [PDF]

G. Henry, I. Brivanlou, D. Kessler, A Hemmati-Brivanlou, and D. Melton
TGF-beta signals and a pattern in Xenopus laevis endodermal development
Development, January 3, 1996; 122(3): 1007 - 1015.
[Abstract] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Kessler, D. S.

Articles by Melton, D. A.

Search for Related Content

PubMed

PubMed Citation

Articles by Kessler, D. S.

Articles by Melton, D. A.

				Y. Kurotaki, K. Hatta, K. Nakao, Y.-i. Nabeshima, and T. Fujimori Blastocyst Axis Is Specified Independently of Early Cell Lineage But Aligns with the ZP Shape Science, May 4, 2007; 316(5825): 719 - 723. [Abstract] [Full Text] [PDF]

				S. Sopory, S. M. Nelsen, C. Degnin, C. Wong, and J. L. Christian Regulation of Bone Morphogenetic Protein-4 Activity by Sequence Elements within the Prodomain J. Biol. Chem., November 10, 2006; 281(45): 34021 - 34031. [Abstract] [Full Text] [PDF]

				K. CZAPLINSKI and I. W. MATTAJ 40LoVe interacts with Vg1RBP/Vera and hnRNP I in binding the Vg1-Localization Element RNA, February 1, 2006; 12(2): 213 - 222. [Abstract] [Full Text] [PDF]

				C. Chen, S. M. Ware, A. Sato, D. E. Houston-Hawkins, R. Habas, M. M. Matzuk, M. M. Shen, and C. W. Brown The Vg1-related protein Gdf3 acts in a Nodal signaling pathway in the pre-gastrulation mouse embryo Development, January 15, 2006; 133(2): 319 - 329. [Abstract] [Full Text] [PDF]

				B. Birsoy, M. Kofron, K. Schaible, C. Wylie, and J. Heasman Vg1 is an essential signaling molecule in Xenopus development Development, January 1, 2006; 133(1): 15 - 20. [Abstract] [Full Text] [PDF]

				M. Kloc, K. Wilk, D. Vargas, Y. Shirato, S. Bilinski, and L. D. Etkin Potential structural role of non-coding and coding RNAs in the organization of the cytoskeleton at the vegetal cortex of Xenopus oocytes Development, August 1, 2005; 132(15): 3445 - 3457. [Abstract] [Full Text] [PDF]

				B. Birsoy, L. Berg, P. H. Williams, J. C. Smith, C. C. Wylie, J. L. Christian, and J. Heasman XPACE4 is a localized pro-protein convertase required for mesoderm induction and the cleavage of specific TGF{beta} proteins in Xenopus development Development, February 1, 2005; 132(3): 591 - 602. [Abstract] [Full Text] [PDF]

				T. L. Kress, Y. J. Yoon, and K. L. Mowry Nuclear RNP complex assembly initiates cytoplasmic RNA localization J. Cell Biol., April 26, 2004; 165(2): 203 - 211. [Abstract] [Full Text] [PDF]

				S. K. Cheng, F. Olale, J. T. Bennett, A. H. Brivanlou, and A. F. Schier EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1 Genes & Dev., January 1, 2003; 17(1): 31 - 36. [Abstract] [Full Text] [PDF]

				Y. Cui, R. Hackenmiller, L. Berg, F. Jean, T. Nakayama, G. Thomas, and J. L. Christian The activity and signaling range of mature BMP-4 is regulated by sequential cleavage at two sites within the prodomain of the precursor Genes & Dev., November 1, 2001; 15(21): 2797 - 2802. [Abstract] [Full Text] [PDF]

				S Faure, M. Lee, T Keller, P ten Dijke, and M Whitman Endogenous patterns of TGFbeta superfamily signaling during early Xenopus development Development, January 7, 2000; 127(13): 2917 - 2931. [Abstract] [PDF]

				R Vignali, L Poggi, F Madeddu, and G Barsacchi HNF1(beta) is required for mesoderm induction in the Xenopus embryo Development, January 4, 2000; 127(7): 1455 - 1465. [Abstract] [PDF]

				J. Aaltonen, M. P. Laitinen, K. Vuojolainen, R. Jaatinen, N. Horelli-Kuitunen, L. Seppä, H. Louhio, T. Tuuri, J. Sjöberg, R. Bützow, et al. Human Growth Differentiation Factor 9 (GDF-9) and Its Novel Homolog GDF-9B Are Expressed in Oocytes during Early Folliculogenesis J. Clin. Endocrinol. Metab., August 1, 1999; 84(8): 2744 - 2750. [Abstract] [Full Text]

				A. Ramsdell and H. Yost Cardiac looping and the vertebrate left-right axis: antagonism of left-sided Vg1 activity by a right-sided ALK2-dependent BMP pathway Development, January 12, 1999; 126(23): 5195 - 5205. [Abstract] [PDF]

				M Watanabe and M Whitman FAST-1 is a key maternal effector of mesoderm inducers in the early Xenopus embryo Development, January 12, 1999; 126(24): 5621 - 5634. [Abstract] [PDF]

				A. Chan, M Kloc, and L. Etkin fatvg encodes a new localized RNA that uses a 25-nucleotide element (FVLE1) to localize to the vegetal cortex of Xenopus oocytes Development, January 11, 1999; 126(22): 4943 - 4953. [Abstract] [PDF]

				C Chang and A Hemmati-Brivanlou Xenopus GDF6, a new antagonist of noggin and a partner of BMPs Development, January 8, 1999; 126(15): 3347 - 3357. [Abstract] [PDF]

				Z Gu, E. Reynolds, J Song, H Lei, A Feijen, L Yu, W He, D. MacLaughlin, J van den Eijnden-van Raaij, P. Donahoe, et al. The type I serine/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo Development, January 6, 1999; 126(11): 2551 - 2561. [Abstract] [PDF]

				K Fekany, Y Yamanaka, T Leung, H. Sirotkin, J Topczewski, M. Gates, M Hibi, A Renucci, D Stemple, A Radbill, et al. The zebrafish bozozok locus encodes Dharma, a homeodomain protein essential for induction of gastrula organizer and dorsoanterior embryonic structures Development, January 4, 1999; 126(7): 1427 - 1438. [Abstract] [PDF]

				B. Sun, S. Bush, L. Collins-Racie, E. LaVallie, E. DiBlasio-Smith, N. Wolfman, J. McCoy, and H. Sive derriere: a TGF-beta family member required for posterior development in Xenopus Development, January 4, 1999; 126(7): 1467 - 1482. [Abstract] [PDF]

				D. Szüts, S. Eresh, and M. Bienz Functional intertwining of Dpp and EGFR signaling during Drosophila endoderm�induction Genes & Dev., July 1, 1998; 12(13): 2022 - 2035. [Abstract] [Full Text]

				Y. Yamane, R. Tohno-oka, S. Yamada, S. Furuya, K. Shiokawa, Y. Hirabayashi, H. Sugino, and K. Sugahara Molecular Characterization of Xenopus Embryo Heparan Sulfate. DIFFERENTIAL STRUCTURAL REQUIREMENTS FOR THE SPECIFIC BINDING TO BASIC FIBROBLAST GROWTH FACTOR AND FOLLISTATIN J. Biol. Chem., March 27, 1998; 273(13): 7375 - 7381. [Abstract] [Full Text] [PDF]

				E. Joseph and D. Melton Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos Development, January 7, 1998; 125(14): 2677 - 2685. [Abstract] [PDF]

				M. L. Rebbert and I. B. Dawid Transcriptional regulation of the Xlim-1 gene by activin is mediated by an element in intron�I PNAS, September 2, 1997; 94(18): 9717 - 9722. [Abstract] [Full Text] [PDF]

				D Gautreau, C. Cote, and K. Mowry Two copies of a subelement from the Vg1 RNA localization sequence are sufficient to direct vegetal localization in Xenopus oocytes Development, January 12, 1997; 124(24): 5013 - 5020. [Abstract] [PDF]

				S. Shah, I Skromne, C. Hume, D. Kessler, K. Lee, C. Stern, and J Dodd Misexpression of chick Vg1 in the marginal zone induces primitive streak formation Development, January 12, 1997; 124(24): 5127 - 5138. [Abstract] [PDF]

				A. Candia, T Watabe, S. Hawley, D Onichtchouk, Y Zhang, R Derynck, C Niehrs, and K. Cho Cellular interpretation of multiple TGF-beta signals: intracellular antagonism between activin/BVg1 and BMP-2/4 signaling mediated by Smads Development, January 11, 1997; 124(22): 4467 - 4480. [Abstract] [PDF]

				R Dosch, V Gawantka, H Delius, C Blumenstock, and C Niehrs Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus Development, January 6, 1997; 124(12): 2325 - 2334. [Abstract] [PDF]

				S. Witta and S. Sato XIPOU 2 is a potential regulator of Spemann's Organizer Development, January 3, 1997; 124(6): 1179 - 1189. [Abstract] [PDF]

				C Chang, P. Wilson, L. Mathews, and A Hemmati-Brivanlou A Xenopus type I activin receptor mediates mesodermal but not neural specification during embryogenesis Development, January 2, 1997; 124(4): 827 - 837. [Abstract] [PDF]