How the Hox gene Ultrabithorax specifies two different segments: the significance of spatial and temporal regulation within metameres

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Akam, M. E (1983). The location of Ultrabithorax transcripts in Drosophila tissue sections. EMBO J 2, 2075-2084.[Medline]

Artero, R. D., Akam, M. and Perez-Alonso, M (1992). Oligonucleotide probes detect splicing variants in situ in Drosophila embryos. Nucleic Acid Res 20, 5687-5690.[Abstract/Free Full Text]

Beachy, P. A., Helfand, S. L. and Hogness, D. S (1985). Segmental distribution of Bithorax complex proteins during Drosophila development. Nature 313, 545-551.[Medline]

Bender, W., Akam, M., Karch, F., Beachy, P. A., Peifer, M., Spierer, P., Lewis, E.B., and Hogness, D. S (1983). Molecular genetics of the Bithorax complex in Drosophila melanogaster. Science 221, 23-29.[Abstract/Free Full Text]

Blochinger, K., Bodmer, R., Jan, L. Y. and Jan, Y. N (1990). Patterns of expression of Cut, a protein required for external sensory organ development in wild-type and cut mutant Drosophila embryos. Genes Dev 4, 1322-1331.[Abstract/Free Full Text]

Busturia, A., Vernos, I., Mac\222as, A., Casanova, J. A. and Morata, G (1990). Different forms of Ultrabithorax proteins generated by alternative splicing are functionally equivalent. EMBO J 9, 3551-3555.[Medline]

Carroll, S. B., DiNardo, S., O'Farrell, P. H., White, R. A. and Scott, M. P (1988). Temporal and spatial relationships between segmentation and homeotic gene expression in Drosophila embryos: distributions of the fushi tarazu, engrailed, Sex combs reduced, Antennapedia, and Ultrabithorax proteins. Genes Dev 2, 350-60.[Abstract/Free Full Text]

Castelli-Gair, J., Greig, S., Micklem, G. and Akam, M (1994). Dissecting the temporal requirements for homeotic gene function. Development 120, 1983-1995.[Abstract]

Cohen, S. M (1990). Specification of limb development in the Drosophila embryo by positional cues from segmentation genes. Nature 343, 173-177.[Medline]

Cohen, B., Simcox, A. A. and Cohen, S. M (1993). Allocation of the thoracic imaginal primordia in the Drosophila embryo. Development 117, 597-608.[Abstract]

Cohen, S. M. and Jurgens, G (1989). Proximal-distal pattern fomation in Drosophila : cell autonomous requirement for Distal-less gene activity in limb development. EMBO J 8, 2045-2055.[Medline]

Dambly-Chaudiere, C. and Ghysen, A (1987). Independent subpatterns ofsense organs require independent genes of the achaete-scute complex in Drosophila larvae. Genes Dev 1, 297-306.[Abstract/Free Full Text]

Dambly-Chaudiere, C., Jamet, E., Burri, M., Bopp, D., Basler, K., Hafen, E., Dumont, N., Spielmann, P., Ghysen, A. and Noll, M (1992). The paired box gene pox neuro : a determinant of poly-innervated sense organs in Drosophila. Cell 69, 159-172.[Medline]

Duncan, I (1987). The Bithorax complex. Ann. Rev. Genet 21, 285-319.[Medline]

Gibson, G. and Gehring, W. J (1988). Head and thoracic transformations caused by ectopic expression of Antennapedia during Drosophila development. Development 102, 657-675.[Abstract/Free Full Text]

Gonz\207lez-Reyes, A. and Morata, G (1990). The developmental effect of overexpressing a Ubx product in Drosophila embryos is dependent on its interactions with other homeotic products. Cell 61, 515-522.[Medline]

Gonz\207lez-Reyes, A., Urqu\222a, N., Gehring, W., Struhl, G. and Morata, G (1990). Are cross regulatory interactions between homeotic genes functionally significant?. Nature 344, 78-80.[Medline]

Hafen, E., Levine, M. and Gehring, W. J (1984). Regulation of Antennapedia transcript distribution by the Bithorax complex in Drosophila. Nature 307, 287-289.[Medline]

Heuer, J. G. and Kaufman, T. C (1992). Homeotic genes have specific funcional roles in the establishment of the Drosophila embryonic peripheral nervous system. Development 115, 35-47.[Abstract]

Irvine, K. D., Helfand, S. L. and Hogness, D. S (1991). The large upstream control region of the Drosophila homeotic gene Ultrabithorax. Development 111, 407-424.[Abstract]

Irvine, K. D., Botas, J., Jha, S., Mann, R. S. and Hogness, D. S (1993). Negative autoregulation by Ultrabithorax controls the level and pattern of its expression. Development 117, 387-399.[Abstract]

Kaufman, T. C., Lewis, R. and Wakimoto, B (1980). Cytogenetic analysis of chromosome 3 in Drosophila melanogaster : the homeotic gene complex in polytene chromosome interval 84 A-B. Genetics 94, 115-133.[Abstract/Free Full Text]

Keilin, D (1911). Sur certaines organes sensitifs constants chez les larves de Dipteres et leur signification probable. C.R. Hebd. Seances Acad. Sci 153, 977-979.

Kelsh, R., Weinzierl, R. O. J., White, R. A. H. and Akam, M (1994). Homeotic gene expression in the locust Schistocerca : an antibody that detects conserved epitopes in Ultrabithorax and abdominal-A proteins. Dev. Genet 15, 19-31.[Medline]

Kornfeld, K., Saint, R. B., Beachy, P. A., Harte, P. J., Peattie, D. A. and Hogness, D. S (1989). Structure and expression of a family of Ultrabithorax mRNAs generated by alternative splicing and polyadenylation in Drosophila. Genes Dev 3, 243-258.[Abstract/Free Full Text]

Lawrence, P. A. and Morata, G (1994). Homeobox genes: their function in Drosophila segmentation and pattern formation. Cell 78, 181-189.[Medline]

Lewis, E. B (1978). A gene complex controlling segmentation in Drosophila. Nature 276, 565-570.[Medline]

Lopez, A. J. and Hogness, D. S (1991). Immunochemical dissection of the Ultrabithorax homeoprotein family in Drosophila melanogaster. Proc. Nat. Acad. Sci.USA 88, 9924-9928.[Abstract/Free Full Text]

Mann, R. S (1994). engrailed -mediated repression of Ultrabithorax is necessary for the parasegment 6 identity in Drosophila. Development 120, 3205-3212.[Abstract]

Mann, R. S. and Hogness, D. S (1990). Functional dissection of Ultrabithorax proteins in D. melanogaster. Cell 60, 597-610.[Medline]

Mart\222nez Arias, A. and Lawrence, P. A (1985). Parasegments and compartments in the Drosophila embryo. Nature 313, 639-642.[Medline]

Mart\222nez Arias, A. and White, R. A. H (1988). Ultrabithorax and engrailed expression in Drosophila embryos mutant for segmentation genes of the pair-rule class. Development 102, 325-338.[Abstract]

Morata, G. and Kerridge, S (1981). Sequential functions of the bithorax complex in Drosophila. Nature 290, 778-781.[Medline]

Muller, J. and Bienz, M (1991). Long range repression conferring boundaries of Ultrabithorax expression in the Drosophila embryo. EMBO J 10, 3147-3155.[Medline]

O'Connor, M. B., Binari, R., Perkins, L. A. and Bender, W (1988). Alternative RNA products from the Ultrabithorax domain of the bithorax complex. EMBO J 7, 435-445.[Medline]

O'Hara, E., Cohen, B., Cohen, S. M. and McGinnis, W (1993). Distal-les is a downstream gene of Deformed required for ventral maxillary identity. Development 117, 847-856.[Abstract]

Rauskolb, C., Peifer, M. and Wieschaus, E (1993). extradenticle , a regulator of homeotic gene activity, is a homolog of the homeobox containing human proto-oncogene pbx1. Cell 74, 1101-1112.[Medline]

Ray, R. P., Arora, C., Nusslein-Volhard, C. and Gelbart, W (1991). Thecontrol of cell fate along the dorsal-ventral axis of the Drosophila embryo. Development 113, 35-54.[Abstract]

S\207nchez-Herrero, E., Vernos, I., Marco, R. and Morata, G (1985). Genetic organisation of the Drosophila Bithorax complex. Nature 313, 108-113.[Medline]

Sato, T. and Denell, R. E (1985). Homoeosis in Drosophila : anterior and posterior transformations of Polycomb lethal embryos. Dev. Biol 110, 53-64.[Medline]

Simon, J., Chiang, A., Bender, W., Shimell, M. J. and O'Connor, M (1993). Elements of the Drosophila Bithorax complex that mediate repression by Polycomb group products. Dev. Biol 158, 131-144.[Medline]

Simon, J., Peifer, M., Bender, W. and O'Connor, M. O (1990). Regulatory elements of the Bithorax complex that control expression along the anterior-posterior axis. EMBO J 9, 3945-3956.[Medline]

Smolik-Utlaut, S. M (1990). Dosage requirements of Ultrabithorax and bithoraxoid in the determination of segment identity in Drosophila melanogaster. Genetics 124, 357-66.[Abstract]

St. Johnston, D. and Gelbart, W (1987). Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo. EMBO J 6, 2785-2791.[Medline]

Struhl, G (1981). A homeotic mutation transforming leg to antenna in Drosophila. Nature 292, 635-638.[Medline]

Struhl, G (1982). Genes controlling segmental specification in the Drosophila thorax. Proc. Natl. Acad. Sci. USA 79, 7380-7384.[Abstract/Free Full Text]

Struhl, G. and White, R. A. H (1985). Regulation of the Ultrabithorax gene of Drosophila by the other Bithorax complex genes. Cell 43, 507-519.[Medline]

Subramaniam, V., Bomze, H. M. and Lopez, A. J (1994). Functional differences between Ultrabithorax protein isoforms in Drosophila melanogaster \320 evidence from elimination, substitution and ectopic expression of specific isoforms. Genetics 136, 979-991.[Abstract]

Tautz, D. and Pfeifle, C (1989). A non-radioactive in situ hybridizationmethod for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma 98, 81-85.[Medline]

Tiong, S., Bone, L. M. and Whittle, J. R (1985). Recessive lethal mutations within the bithorax complex in Drosophila. Mol. Gen. Genet 200, 335-42.[Medline]

Vachon, G., Cohen, B., Pfeifle, C., McGuffin, M. E., Botas, J. and Cohen, S. M (1992). Homeotic genes of the Bithorax complex repress limb development in the abdomen of the Drosophila embryo through target gene Distal-less. Cell 71, 437-450.[Medline]

Van den Heuvel, M., Nusse, R., Johnston, P. and Lawrence, P. A (1989). Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell 59, 739-749.[Medline]

Wakimoto, B. T. and Kaufman, T. C (1981). Analysis of larval segmentation in lethal genotypes associated with the Antennapedia gene complex in Drosophilamelanogaster. Dev. Biol 81, 51-64.[Medline]

Wang, B. B., Muller-Immergluck, M. M., Austin, J., Robinson, N. T., Chisholm, A. and Kenyon, C (1993). A homeotic gene cluster patterns the anteroposterior body axis of C. elegans. Cell 74, 29-42.[Medline]

White, R. A. H. and Wilcox, M (1984). Protein products of the Bithorax complex in Drosophila. Cell 39, 163-171.[Medline]

Zeng, W., Andrew, D. J., Mathies, L. D., Horner, M. A. and Scott, M. P (1993). Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity. Development 118, 339-352.[Abstract]

Zhang, C.-C., Muller, J., Hoch, M., J\212ckle, H. and Bienz, M (1991). Target sequences for hunchback in a control region conferring Ultrabithorax expression boundaries. Development 113, 1171-1179.[Abstract]

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				D. Foronda, B. Estrada, L. de Navas, and E. Sanchez-Herrero Requirement of abdominal-A and Abdominal-B in the developing genitalia of Drosophila breaks the posterior downregulation rule Development, January 1, 2006; 133(1): 117 - 127. [Abstract] [Full Text] [PDF]

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				J. Maloof and C Kenyon The Hox gene lin-39 is required during C. elegans vulval induction to select the outcome of Ras signaling Development, January 1, 1998; 125(2): 181 - 190. [Abstract] [PDF]

				P. Arlotta, A. Rustighi, F. Mantovani, G. Manfioletti, V. Giancotti, G. Tell, and G. Damante High Mobility Group I Proteins Interfere with the Homeodomains Binding to DNA J. Biol. Chem., November 21, 1997; 272(47): 29904 - 29910. [Abstract] [Full Text] [PDF]

				A Percival-Smith, J Weber, E Gilfoyle, and P Wilson Genetic characterization of the role of the two HOX proteins, Proboscipedia and Sex Combs Reduced, in determination of adult antennal, tarsal, maxillary palp and proboscis identities in Drosophila melanogaster Development, January 12, 1997; 124(24): 5049 - 5062. [Abstract] [PDF]

				M. Biggin and W McGinnis Regulation of segmentation and segmental identity by Drosophila homeoproteins: the role of DNA binding in functional activity and specificity Development, January 11, 1997; 124(22): 4425 - 4433. [Abstract] [PDF]

				B. Rogers, M. Peterson, and T. Kaufman Evolution of the insect body plan as revealed by the Sex combs reduced expression pattern Development, January 1, 1997; 124(1): 149 - 157. [Abstract] [PDF]