Two distinct phases of apoptosis in mammary gland involution: proteinase-independent and -dependent pathways

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M. Kingsley-Kallesen, S. S. Mukhopadhyay, S. L. Wyszomierski, S. Schanler, G. Schutz, and J. M. Rosen
The Mineralocorticoid Receptor May Compensate for the Loss of the Glucocorticoid Receptor at Specific Stages of Mammary Gland Development
Mol. Endocrinol., September 1, 2002; 16(9): 2008 - 2018.
[Abstract] [Full Text] [PDF]

S. R. Master, J. L. Hartman, C. M. D'Cruz, S. E. Moody, E. A. Keiper, S. I. Ha, J. D. Cox, G. K. Belka, and L. A. Chodosh
Functional Microarray Analysis of Mammary Organogenesis Reveals a Developmental Role in Adaptive Thermogenesis
Mol. Endocrinol., June 1, 2002; 16(6): 1185 - 1203.
[Abstract] [Full Text] [PDF]

J. Mengwasser, F.-T. Liu, and J. P. Sleeman
Galectin-3 is strongly up-regulated in nonapoptosing mammary epithelial cells during rat mammary gland involution
Glycobiology, February 1, 2002; 12(2): 129 - 134.
[Abstract] [Full Text] [PDF]

S. Parrinello, C. Q. Lin, K. Murata, Y. Itahana, J. Singh, A. Krtolica, J. Campisi, and P.-Y. Desprez
Id-1, ITF-2, and Id-2 Comprise a Network of Helix-Loop-Helix Proteins That Regulate Mammary Epithelial Cell Proliferation, Differentiation, and Apoptosis
J. Biol. Chem., October 12, 2001; 276(42): 39213 - 39219.
[Abstract] [Full Text] [PDF]

K. L. Schwertfeger, M. M. Richert, and S. M. Anderson
Mammary Gland Involution Is Delayed by Activated Akt in Transgenic Mice
Mol. Endocrinol., June 1, 2001; 15(6): 867 - 881.
[Abstract] [Full Text] [PDF]

J. Mengwasser and J. P. Sleeman
Expression of M-N#1, a histo-blood group B-like antigen, is strongly up-regulated in nonapoptosing mammary epithelial cells during rat mammary gland involution
Glycobiology, June 1, 2001; 11(6): 441 - 449.
[Abstract] [Full Text] [PDF]

D. L. Hadsell, T. Alexeenko, Y. Klemintidis, D. Torres, and A. V. Lee
Inability of Overexpressed des(1-3)Human Insulin-Like Growth Factor I (IGF-I) to Inhibit Forced Mammary Gland Involution Is Associated with Decreased Expression of IGF Signaling Molecules
Endocrinology, April 1, 2001; 142(4): 1479 - 1488.
[Abstract] [Full Text]

C. M. Alexander, S. Selvarajan, J. Mudgett, and Z. Werb
Stromelysin-1 Regulates Adipogenesis during Mammary Gland Involution
J. Cell Biol., February 12, 2001; 152(4): 693 - 703.
[Abstract] [Full Text] [PDF]

A. Shilkaitis, J. Graves, R. R. Mehta, L. Hu, M. You, R. Lubet, V. Steele, G. Kelloff, and K. Christov
Bcl-2 and Bax Are Differentially Expressed in Hyperplastic, Premalignant, and Malignant Lesions of Mammary Carcinogenesis
Cell Growth Differ., August 1, 2000; 11(8): 437 - 445.
[Abstract] [Full Text]

T. M. Casey, A. Boecker, J.-F. Chiu, and K. Plaut
Glucocorticoids Maintain the Extracellular Matrix of Differentiated Mammary Tissue During Explant and Whole Organ Culture
Experimental Biology and Medicine, June 1, 2000; 224(2): 76 - 86.
[Abstract] [Full Text]

R. W. E. Clarkson, J. L. Heeley, R. Chapman, F. Aillet, R. T. Hay, A. Wyllie, and C. J. Watson
NF-kappa B Inhibits Apoptosis in Murine Mammary Epithelia
J. Biol. Chem., April 21, 2000; 275(17): 12737 - 12742.
[Abstract] [Full Text] [PDF]

K. Nakajima, A. Takahashi, and Y. Yaoita
Structure, Expression, and Function of the Xenopus laevis Caspase Family
J. Biol. Chem., March 31, 2000; 275(14): 10484 - 10491.
[Abstract] [Full Text] [PDF]

S. DAMJANOVSKI, M. PUZIANOWSKA-KUZNICKA, A. ISHUZUYA-OKA, and Y.-B. SHI
Differential regulation of three thyroid hormone-responsive matrix metalloproteinase genes implicates distinct functions during frog embryogenesis
FASEB J, March 1, 2000; 14(3): 503 - 510.
[Abstract] [Full Text]

T. J. Moran, S. Gray, C. A. Mikosz, and S. D. Conzen
The Glucocorticoid Receptor Mediates a Survival Signal in Human Mammary Epithelial Cells
Cancer Res., February 1, 2000; 60(4): 867 - 872.

				D. C. Radisky and J. A. Przybylo Matrix Metalloproteinase-induced Fibrosis and Malignancy in Breast and Lung Proceedings of the ATS, April 15, 2008; 5(3): 316 - 322. [Abstract] [Full Text] [PDF]

				J. Monks, C. Smith-Steinhart, E. R. Kruk, V. A. Fadok, and P. M. Henson Epithelial Cells Remove Apoptotic Epithelial Cells During Post-Lactation Involution of the Mouse Mammary Gland Biol Reprod, April 1, 2008; 78(4): 586 - 594. [Abstract] [Full Text] [PDF]

				A. J Brennan, J. A Sharp, E. Khalil, M. R Digby, S. L Mailer, C. M Lefevre, and K. R Nicholas A population of mammary epithelial cells do not require hormones or growth factors to survive J. Endocrinol., March 1, 2008; 196(3): 483 - 496. [Abstract] [Full Text] [PDF]

				M. Hiremath, J. P. Lydon, and P. Cowin The pattern of {beta}-catenin responsiveness within the mammary gland is regulated by progesterone receptor Development, October 15, 2007; 134(20): 3703 - 3712. [Abstract] [Full Text] [PDF]

				S. Elmore Apoptosis: A Review of Programmed Cell Death Toxicol Pathol, June 1, 2007; 35(4): 495 - 516. [Abstract] [Full Text] [PDF]

				A. J. Brennan, J. A. Sharp, C. Lefevre, D. Topcic, A. Auguste, M. Digby, and K. R. Nicholas The Tammar Wallaby and Fur Seal: Models to Examine Local Control of Lactation J Dairy Sci, June 1, 2007; 90(13_suppl): E66 - E75. [Abstract] [Full Text] [PDF]

				Y. Ning, B. Hoang, A. G. P. Schuller, T. P. Cominski, M.-S. Hsu, T. L. Wood, and J. E. Pintar Delayed Mammary Gland Involution in Mice with Mutation of the Insulin-Like Growth Factor Binding Protein 5 Gene Endocrinology, May 1, 2007; 148(5): 2138 - 2147. [Abstract] [Full Text] [PDF]

				R. Zaragoza, A. Gimeno, V. J. Miralles, E. R. Garcia-Trevijano, R. Carmena, C. Garcia, M. Mata, I. R. Puertes, L. Torres, and J. R. Vina Retinoids induce MMP-9 expression through RAR{alpha} during mammary gland remodeling Am J Physiol Endocrinol Metab, April 1, 2007; 292(4): E1140 - E1148. [Abstract] [Full Text] [PDF]

				S. Ollier, C. Robert-Granie, L. Bernard, Y. Chilliard, and C. Leroux Mammary Transcriptome Analysis of Food-Deprived Lactating Goats Highlights Genes Involved in Milk Secretion and Programmed Cell Death J. Nutr., March 1, 2007; 137(3): 560 - 567. [Abstract] [Full Text] [PDF]

				A. Rabot, F. Sinowatz, B. Berisha, H. H. D. Meyer, and D. Schams Expression and Localization of Extracellular Matrix-Degrading Proteinases and Their Inhibitors in the Bovine Mammary Gland During Development, Function, and Involution J Dairy Sci, February 1, 2007; 90(2): 740 - 748. [Abstract] [Full Text] [PDF]

				S. J. Hatsell and P. Cowin Gli3-mediated repression of Hedgehog targets is required for normal mammary development Development, September 15, 2006; 133(18): 3661 - 3670. [Abstract] [Full Text] [PDF]

				F. O. Baxter, P. J. Came, K. Abell, B. Kedjouar, M. Huth, K. Rajewsky, M. Pasparakis, and C. J. Watson IKK{beta}/2 induces TWEAK and apoptosis in mammary epithelial cells Development, September 1, 2006; 133(17): 3485 - 3494. [Abstract] [Full Text] [PDF]

				L. Fu, A. Tomita, H. Wang, D. R. Buchholz, and Y.-B. Shi Transcriptional Regulation of the Xenopus laevis Stromelysin-3 Gene by Thyroid Hormone Is Mediated by a DNA Element in the First Intron J. Biol. Chem., June 23, 2006; 281(25): 16870 - 16878. [Abstract] [Full Text] [PDF]

				D J Flint, M Boutinaud, C B A Whitelaw, G J Allan, and A F Kolb Prolactin inhibits cell loss and decreases matrix metalloproteinase expression in the involuting mouse mammary gland but fails to prevent cell loss in the mammary glands of mice expressing IGFBP-5 as a mammary transgene. J. Mol. Endocrinol., June 1, 2006; 36(3): 435 - 448. [Abstract] [Full Text] [PDF]

				A. M. Sorrell, J. H. Shand, E. Tonner, M. Gamberoni, P. A. Accorsi, J. Beattie, G. J. Allan, and D. J. Flint Insulin-like Growth Factor-binding Protein-5 Activates Plasminogen by Interaction with Tissue Plasminogen Activator, Independently of Its Ability to Bind to Plasminogen Activator Inhibitor-1, Insulin-like Growth Factor-I, or Heparin J. Biol. Chem., April 21, 2006; 281(16): 10883 - 10889. [Abstract] [Full Text] [PDF]

				F. Mannello, G. A.M. Tonti, G. P. Bagnara, and S. Papa Role and Function of Matrix Metalloproteinases in the Differentiation and Biological Characterization of Mesenchymal Stem Cells Stem Cells, March 1, 2006; 24(3): 475 - 481. [Abstract] [Full Text] [PDF]

				S. M. McDaniel, K. K. Rumer, S. L. Biroc, R. P. Metz, M. Singh, W. Porter, and P. Schedin Remodeling of the Mammary Microenvironment after Lactation Promotes Breast Tumor Cell Metastasis Am. J. Pathol., February 1, 2006; 168(2): 608 - 620. [Abstract] [Full Text] [PDF]

				M. Simian, A. Molinolo, and C. Lanari Involvement of Matrix Metalloproteinase Activity in Hormone-Induced Mammary Tumor Regression Am. J. Pathol., January 1, 2006; 168(1): 270 - 279. [Abstract] [Full Text] [PDF]

				K. Atabai, R. Fernandez, X. Huang, I. Ueki, A. Kline, Y. Li, S. Sadatmansoori, C. Smith-Steinhart, W. Zhu, R. Pytela, et al. Mfge8 Is Critical for Mammary Gland Remodeling during Involution Mol. Biol. Cell, December 1, 2005; 16(12): 5528 - 5537. [Abstract] [Full Text] [PDF]

				R. Hanayama and S. Nagata Impaired involution of mammary glands in the absence of milk fat globule EGF factor 8 PNAS, November 15, 2005; 102(46): 16886 - 16891. [Abstract] [Full Text] [PDF]

				M. Thangaraju, M. Rudelius, B. Bierie, M. Raffeld, S. Sharan, L. Hennighausen, A-M. Huang, and E. Sterneck C/EBP{delta} is a crucial regulator of pro-apoptotic gene expression during mammary gland involution Development, November 1, 2005; 132(21): 4675 - 4685. [Abstract] [Full Text] [PDF]

				T. X. Pedersen, C. J. Pennington, K. Almholt, I. J. Christensen, B. S. Nielsen, D. R. Edwards, J. Romer, K. Dano, and M. Johnsen Extracellular protease mRNAs are predominantly expressed in the stromal areas of microdissected mouse breast carcinomas Carcinogenesis, July 1, 2005; 26(7): 1233 - 1240. [Abstract] [Full Text] [PDF]

				M. K. McClintock, S. D. Conzen, S. Gehlert, C. Masi, and F. Olopade Mammary Cancer and Social Interactions: Identifying Multiple Environments That Regulate Gene Expression Throughout the Life Span J. Gerontol. B. Psychol. Sci. Soc. Sci., March 1, 2005; 60(suppl_Special_Issue_1): 32 - 41. [Abstract] [Full Text] [PDF]

				T. M. Wintermantel, D. Bock, V. Fleig, E. F. Greiner, and G. Schutz The Epithelial Glucocorticoid Receptor Is Required for the Normal Timing of Cell Proliferation during Mammary Lobuloalveolar Development but Is Dispensable for Milk Production Mol. Endocrinol., February 1, 2005; 19(2): 340 - 349. [Abstract] [Full Text] [PDF]

				K. A. Green, M. J. Naylor, E. T. Lowe, P. Wang, E. Marshman, and C. H. Streuli Caspase-mediated Cleavage of Insulin Receptor Substrate J. Biol. Chem., June 11, 2004; 279(24): 25149 - 25156. [Abstract] [Full Text] [PDF]

				X. Zhou, F. R. Murphy, N. Gehdu, J. Zhang, J. P. Iredale, and R. C. Benyon Engagement of {alpha}v{beta}3 Integrin Regulates Proliferation and Apoptosis of Hepatic Stellate Cells J. Biol. Chem., June 4, 2004; 279(23): 23996 - 24006. [Abstract] [Full Text] [PDF]

				B. S. Wiseman, M. D. Sternlicht, L. R. Lund, C. M. Alexander, J. Mott, M. J. Bissell, P. Soloway, S. Itohara, and Z. Werb Site-specific inductive and inhibitory activities of MMP-2 and MMP-3 orchestrate mammary gland branching morphogenesis J. Cell Biol., September 15, 2003; 162(6): 1123 - 1133. [Abstract] [Full Text] [PDF]

				H. Solberg, J. Rinkenberger, K. Dano, Z. Werb, and L. R. Lund A functional overlap of plasminogen and MMPs regulates vascularization during placental development Development, September 15, 2003; 130(18): 4439 - 4450. [Abstract] [Full Text] [PDF]

				K. L. Schwertfeger, J. L. McManaman, C. A. Palmer, M. C. Neville, and S. M. Anderson Expression of constitutively activated Akt in the mammary gland leads to excess lipid synthesis during pregnancy and lactation J. Lipid Res., June 1, 2003; 44(6): 1100 - 1112. [Abstract] [Full Text] [PDF]

				S. Schenk, E. Hintermann, M. Bilban, N. Koshikawa, C. Hojilla, R. Khokha, and V. Quaranta Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution J. Cell Biol., April 14, 2003; 161(1): 197 - 209. [Abstract] [Full Text] [PDF]