Hoxa-13 and Hoxd-13 play a crucial role in the patterning of the limb autopod

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Coates, M.I (1995). Fish fins or tetrapod limbs- a simple twist of fate?. Current Biol 5, 844-848.[Medline]

Coates, M.I. and Clack, J.A (1990). Polydactyly in the earliest known tetrapod limbs. Nature 347, 66-68.

Crossley, P.H., Minowada, G., MacArthur, C.A. and Martin, G.R (1996). Roles for FGF8 in the induction, initiation, and maintenance of chick limb development. Cell 84, 127-136.[Medline]

Davis, A.P. and Capecchi, M.R (1994). Axial homeosis and appendicular skeleton defects in mice with a targeted disruption of Hoxd-11. Development 120, 2187-2198.[Abstract]

Davis, A.P., Witte, D.P., Hsieh-Li, H.M., Potter, S.S. and Capecchi, M.R (1995). Absence of radius and ulna in mice lacking Hoxa-11 and Hoxd-11. Nature 375, 791-795.[Medline]

Davis, A.P. and Capecchi, M.R (1996). A mutational analysis of the 5' HoxD genes: dissection of genetic interactions during limb development in the mouse. Development 122, 1175-1185.[Abstract]

Dolle, P., Dierich, A., LeMeur, M., Schimmang, T., Schuhbaur, B., Chambon, P. and Duboule, D (1993). Disruption of the Hoxd-13 gene induces localized heterochrony leading to mice with neotenic limbs. Cell 75, 431-441.[Medline]

Dolle, P., Izpisua-Belmonte, J.C., Falkenstein, H., Renucci, A. and Duboule, D (1989). Coordinate expression of the murine Hox-5 complex homeobox-containing genes during limb pattern formation. Nature 342, 767-772.[Medline]

Duboule, D. and Dolle, P (1989). The structural and functional organization of the murine HOX gene family resembles that of Drosophila homeotic genes. EMBO J 8, 1497-1505.[Medline]

Duboule, D (1994). How to make a limb. Science 266, 575-576.[Free Full Text]

Favier, B., Lemeur, M., Chambon, P. and Dolle, P (1995). Axial skeleton homeosis and forelimb malformations in Hoxd-11 mutant mice. Proc. Natl. Acad. Sci. USA 92, 310-314.[Abstract/Free Full Text]

Favier, B., Rijli F.M., Fromental-Ramain C., Fraulob V., Chambon P. and Dolle, P (1996). Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton. Development 122, 449-460.[Abstract]

Francis, P.H., Richardson, M.K., Brickell, P.M. and Tickle, C (1994). Bone morphogenetic proteins and a signalling pathway that controls patterning in the developing chick limb. Development 120, 209-218.[Abstract]

Fromental-Ramain, C., Warot, X., Lakkaraju, S., Favier, B., Haack, H., Birling, C., Dierich, A., Dolle, P. and Chambon, P (1996). Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning. Development 122, 461-472.[Abstract]

Gossler, A., Doetschman, T., Korn, R., Serfling, E. and Kemler, R (1986). Transgenesis by means of blastocyst-derived embryonic stem cell lines. Proc. Natl. Acad. Sci. USA 83, 9065-9069.[Abstract/Free Full Text]

Graham, A., Papalopulu, N. and Krumlauf, R (1989). The murine and Drosophila homeobox gene complexes have common features of organization and expression. Cell 57, 367-378.[Medline]

Haack, H. and Gruss, P (1993). The establishment of murine Hox-1 expression domains during patterning of the limb. Dev. Biol 157, 410-422.[Medline]

Hays, T.S., Duering, R., Robertson, B., Prout, M. and Fuller, M.T (1989). Interacting proteins identified by genetic interactions: A missense mutation in-tubulin fails to complement alleles of the testis-specific -tubulin gene of Drosophila melanogaster. Mol. Cell. Biol 9, 875-884.[Abstract/Free Full Text]

Hummel, K. P (1970). Hypodactyly, a semidominant lethal mutation in mice. J. Hered 61, 219-220.[Free Full Text]

Jegalian, B.G. and De Robertis, E.M (1992). Homeotic transformation in the mouse induced by overexpression of a human Hox-3.3 transgene. Cell 71, 901-910.[Medline]

McCarrick III, J.W., Parnes, J.R., Seong, R.H., Solter, D. and Knowles, B.B (1993). Positive-negative selection gene targeting with the diphtheria toxin A-chain gene in mouse embryonic stem cells. Transgenic Res 2, 183-190.[Medline]

McGinnis, W. and Krumlauf, R (1992). Homeobox genes and axial patterning. Cell 68, 283-302.[Medline]

Morgan, B.A., Izpisua-Belmonte, J.C., Duboule, D. and Tabin, C (1992). Targeted misexpression of Hox-4.6 in the avian limb bud causes apparent homeotic transformations. Nature 358, 236-239.[Medline]

Mortlock, D. P., Post, L. C. and Innis, J. W (1996). The molecular basis of Hypodactyly (Hd): a deletion in Hoxa-13 leads to arrest of digital arch formation. Nature genet 13, 284-289.[Medline]

Muragaki, Y., Mundlos, S., Upton, J. and Olsen, B. R (1996). Altered growth and branching patterns in synpolydactyly caused by mutations in HOXD13. Science 272, 448-451.

Olson, E.N., Arnold, H.-H., Rigby, P.W.J. and Wold, B.J (1996). Knowyour neighbors: three phenotypes in null mutants of the myogenic bHLH gene MRF4. Cell, 85, 1-4.[Medline]

Parr, B.A. and McMahon, A.P (1995). Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374, 350-353.[Medline]

Peterson, R.L., Papenbrock, T., Davda, M.M. and Awgulewitsch, A (1994). The murine HOXC cluster contains five neighboring AbdB-related Hox genes that show unique spatially coordinated expression in posterior embryonic subregions. Mech. Dev 47, 253-260.[Medline]

Raynaud, A. and Clergue-Gazeau, M (1986). Identification des doigts reduits ou manquants dans les pattes des embryons de lezard vert (Lacerta viridis) traites par la cytosine-arabinofuranoside. Comparaison avec les reductions digitales naturelles des especes de reptiles serpentiformes. Arch. Biol 97, 279-299.

Riddle, R.D., Johnson, R.L., Laufer, E. and Tabin, C (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.[Medline]

Rijli, F.M., Dolle, P., Fraulob, V., LeMeur, M. and Chambon, P (1994). Insertion of a targeting construct in a Hoxd-10 allele can influence the control of Hoxd-9 expression. Dev. Dynamics 201, 366-377.[Medline]

Rine, J. and Herskowitz, I (1987). Four genes responsible for a position affect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116, 9-22.[Abstract/Free Full Text]

Small, K.M. and Potter, S.S (1993). Homeotic transformations and limb defects in Hoxa-11 mutant mice. Genes Dev 7, 2318-2328.[Abstract/Free Full Text]

Sordino, P., van der Hoeven, F. and Duboule, D (1995). Hox gene expression in teleost fins and the origin of vertebrate digits. Nature 375, 678-681.[Medline]

Stearns, T. and Botstein, D (1988). Unlinked noncomplementation: Isolation of new conditional-lethal mutations in each of the tubulin genes of Saccharomyces cerevisiae. Genetics 119, 249-260.[Abstract/Free Full Text]

Thomas, K.R. and Capecchi, M.R (1987). Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51, 503-512.[Medline]

Yokouchi, Y., Sasaki, H. and Kuroiwa, A (1991). Homeobox gene expression correlated with the bifurcation process of limb cartilage development. Nature 353, 443-445.[Medline]

Yokouchi, Y., Nakazato, S., Yamamoto, M., Goto, Y., Kameda, T., Iba, H. and Kuroiwa, A (1995). Misexpression of Hoxa-13 induces cartilage homeotic transformation and changes cell adhesiveness in chick limb buds. Genes Dev 9, 2509-2522.[Abstract/Free Full Text]

Zappavigna, V., Sartori, D. and Mavilio, F (1994). Specificity of Hox protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeodomain. Genes Dev 8, 732-744.[Abstract/Free Full Text]

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				M. Towers and C. Tickle Growing models of vertebrate limb development Development, January 15, 2009; 136(2): 179 - 190. [Abstract] [Full Text] [PDF]

				C. Lin, Y. Yin, F. Long, and L. Ma Tissue-specific requirements of {beta}-catenin in external genitalia development Development, August 15, 2008; 135(16): 2815 - 2825. [Abstract] [Full Text] [PDF]

				P. Lu, Y. Yu, Y. Perdue, and Z. Werb The apical ectodermal ridge is a timer for generating distal limb progenitors Development, April 15, 2008; 135(8): 1395 - 1405. [Abstract] [Full Text] [PDF]

				T. Montavon, J.-F. Le Garrec, M. Kerszberg, and D. Duboule Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness Genes & Dev., February 1, 2008; 22(3): 346 - 359. [Abstract] [Full Text] [PDF]

				P. Basu, T. K. Lung, W. Lemsaddek, T. G. Sargent, D. C. Williams Jr, M. Basu, L. C. Redmond, J. B Lingrel, J. L. Haar, and J. A. Lloyd EKLF and KLF2 have compensatory roles in embryonic {beta}-globin gene expression and primitive erythropoiesis Blood, November 1, 2007; 110(9): 3417 - 3425. [Abstract] [Full Text] [PDF]

				W. M. Knosp, C. Saneyoshi, S. Shou, H. P. Bachinger, and H. S. Stadler Elucidation, Quantitative Refinement, and in Vivo Utilization of the HOXA13 DNA Binding Site J. Biol. Chem., March 2, 2007; 282(9): 6843 - 6853. [Abstract] [Full Text] [PDF]

				R. S. Hawley and W. D. Gilliland Sometimes the Result Is Not the Answer: The Truths and the Lies That Come From Using the Complementation Test Genetics, September 1, 2006; 174(1): 5 - 15. [Abstract] [Full Text] [PDF]

				T. D. Capellini, G. Di Giacomo, V. Salsi, A. Brendolan, E. Ferretti, D. Srivastava, V. Zappavigna, and L. Selleri Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression Development, June 1, 2006; 133(11): 2263 - 2273. [Abstract] [Full Text] [PDF]

				T. P. Hill, M. M. Taketo, W. Birchmeier, and C. Hartmann Multiple roles of mesenchymal {beta}-catenin during murine limb patterning Development, April 1, 2006; 133(7): 1219 - 1229. [Abstract] [Full Text] [PDF]

				V. Salsi and V. Zappavigna Hoxd13 and Hoxa13 Directly Control the Expression of the EphA7 Ephrin Tyrosine Kinase Receptor in Developing Limbs J. Biol. Chem., January 27, 2006; 281(4): 1992 - 1999. [Abstract] [Full Text] [PDF]

				C. D. McCabe and J. W. Innis A genomic approach to the identification and characterization of HOXA13 functional binding elements Nucleic Acids Res., November 30, 2005; 33(21): 6782 - 6794. [Abstract] [Full Text] [PDF]

				J. M. Verheyden, M. Lewandoski, C. Deng, B. D. Harfe, and X. Sun Conditional inactivation of Fgfr1 in mouse defines its role in limb bud establishment, outgrowth and digit patterning Development, October 1, 2005; 132(19): 4235 - 4245. [Abstract] [Full Text] [PDF]

				T. M. Williams, M. E. Williams, J. H. Heaton, T. D. Gelehrter, and J. W. Innis Group 13 HOX proteins interact with the MH2 domain of R-Smads and modulate Smad transcriptional activation functions independent of HOX DNA-binding capability Nucleic Acids Res., August 8, 2005; 33(14): 4475 - 4484. [Abstract] [Full Text] [PDF]

				J. Cobb and D. Duboule Comparative analysis of genes downstream of the Hoxd cluster in developing digits and external genitalia Development, July 1, 2005; 132(13): 3055 - 3067. [Abstract] [Full Text] [PDF]

				V. Scott, E. A. Morgan, and H. S. Stadler Genitourinary Functions of Hoxa13 and Hoxd13 J. Biochem., June 1, 2005; 137(6): 671 - 676. [Abstract] [Full Text] [PDF]

				J. W. Innis, D. Mortlock, Z. Chen, M. Ludwig, M. E. Williams, T. M. Williams, C. D. Doyle, Z. Shao, M. Glynn, D. Mikulic, et al. Polyalanine expansion in HOXA13: three new affected families and the molecular consequences in a mouse model Hum. Mol. Genet., November 15, 2004; 13(22): 2841 - 2851. [Abstract] [Full Text] [PDF]

				W. M. Knosp, V. Scott, H. P. Bachinger, and H. S. Stadler HOXA13 regulates the expression of bone morphogenetic proteins 2 and 7 to control distal limb morphogenesis Development, September 15, 2004; 131(18): 4581 - 4592. [Abstract] [Full Text] [PDF]

				A. C. M. Brun, J. M. Bjornsson, M. Magnusson, N. Larsson, P. Leveen, M. Ehinger, E. Nilsson, and S. Karlsson Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells Blood, June 1, 2004; 103(11): 4126 - 4133. [Abstract] [Full Text] [PDF]

				Y. Chen, V. Knezevic, V. Ervin, R. Hutson, Y. Ward, and S. Mackem Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh Development, May 15, 2004; 131(10): 2339 - 2347. [Abstract] [Full Text] [PDF]

				A. M. Boulet and M. R. Capecchi Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod Development, January 15, 2004; 131(2): 299 - 309. [Abstract] [Full Text] [PDF]

				H. Lavoie, F. Debeane, Q.-D. Trinh, J.-F. Turcotte, L.-P. Corbeil-Girard, M.-J. Dicaire, A. Saint-Denis, M. Page, G. A. Rouleau, and B. Brais Polymorphism, shared functions and convergent evolution of genes with sequences coding for polyalanine domains Hum. Mol. Genet., November 15, 2003; 12(22): 2967 - 2979. [Abstract] [Full Text] [PDF]

				M. Suzuki, N. Ueno, and A. Kuroiwa Hox Proteins Functionally Cooperate with the GC Box-binding Protein System through Distinct Domains J. Biol. Chem., August 8, 2003; 278(32): 30148 - 30156. [Abstract] [Full Text] [PDF]

				D. M. Wellik and M. R. Capecchi Hox10 and Hox11 Genes Are Required to Globally Pattern the Mammalian Skeleton Science, July 18, 2003; 301(5631): 363 - 367. [Abstract] [Full Text] [PDF]

				E. A. Morgan, S. B. Nguyen, V. Scott, and H. S. Stadler Loss of Bmp7 and Fgf8 signaling in Hoxa13-mutant mice causes hypospadia Development, July 15, 2003; 130(14): 3095 - 3109. [Abstract] [Full Text] [PDF]

				L Frisen, K Lagerstedt, M Tapper-Persson, I Kockum, and A Nordenskjold A novel duplication in the HOXA13 gene in a family with atypical hand-foot-genital syndrome J. Med. Genet., April 1, 2003; 40(4): e49 - 49. [Full Text] [PDF]

				P Debeer, C Bacchelli, P J Scambler, L De Smet, J-P Fryns, and F R Goodman Severe digital abnormalities in a patient heterozygous for both a novel missense mutation in HOXD13 and a polyalanine tract expansion in HOXA13 J. Med. Genet., November 1, 2002; 39(11): 852 - 856. [Full Text] [PDF]

				H. Y. Chang, J.-T. Chi, S. Dudoit, C. Bondre, M. van de Rijn, D. Botstein, and P. O. Brown Diversity, topographic differentiation, and positional memory in human fibroblasts PNAS, October 1, 2002; 99(20): 12877 - 12882. [Abstract] [Full Text] [PDF]

				P. de Santa Barbara and D. J. Roberts Tail gut endoderm and gut/genitourinary/tail development: a new tissue-specific role for Hoxa13 Development, January 2, 2002; 129(3): 551 - 561. [Abstract] [Full Text] [PDF]

				H. S. Stadler, K. M. Higgins, and M. R. Capecchi Loss of Eph-receptor expression correlates with loss of cell adhesion and chondrogenic capacity in Hoxa13 mutant limbs Development, November 1, 2001; 128(21): 4177 - 4188. [Abstract] [Full Text] [PDF]

				Y. Zhao and S. S. Potter Functional specificity of the Hoxa13 homeobox Development, August 15, 2001; 128(16): 3197 - 3207. [Abstract] [Full Text] [PDF]