The Xvent-2 homeobox gene is part of the BMP-4 signalling pathway controlling [correction of controling] dorsoventral patterning of Xenopus mesoderm

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Arora, K., Dai, H., Kazuko, S. G., Jamal, J., O'Connor, M. B., Letsou, A. and Warrior, R (1995). The drosophila schnurri gene acts in the dpp/TGFsignalling pathway and encodes a transcription factor homologous to the human MBP family. Cell 81, 781-790.[Medline]

Belleville, S., Beauchemin, M., Tremblay, M., Noiseux, N. and Savard, P (1992). Homeobox-containing genes in newt are organized in clusters similar to other vertebrates. Gene 114, 179-186.[Medline]

Candia, A. F, Hu, J., Crosby, J., Lalley, P. A., Noden, D., Nadeau, J. H. and Wright, C. V. E (1992). Mox-1 and Mox-2 define a novel homeobox gene subfamily, and are differentially expressed during early mesodermal patterning in mouse embryos. Development 116, 1123-1136.[Abstract]

Cho, K. W., Blumberg, B., Steinbeisser, H. and De Robertis, E. M (1991). Molecular nature of Spemann's organizer: the role of the Xenopus homeobox gene goosecoid. Cell 67, 1111-1120.[Medline]

Christian, J. L. and Moon, R. T (1993). Interactions between Xwnt-8 and Spemann organizer signalling pathways generate dorsoventral pattern in the embryonic mesoderm of Xenopus. Genes Dev 7, 13-28.[Abstract/Free Full Text]

Dale, L. and Slack, J. M (1987). Regional specification within the mesoderm of early embryos of Xenopuslaevis. Development 100, 279-295.[Abstract/Free Full Text]

Dale, L. and Slack, J. M (1987). Fate map for the 32-cell stage of Xenopus laevis. Development 99, 527-551.[Abstract/Free Full Text]

Dale, L., Howes, G., Price, B. M. and Smith, J. C (1992). Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development. Development 115, 573-585.[Abstract]

Dear, T. N., Sanchez-Garcia, I. and Rabbitts, T. H (1993). The HOX11 gene encodes a DNA-binding nuclear transcription factor belonging to a distinct family of homeobox genes. Proc. Natl Acad. Sci. USA 90, 4431-4435.[Abstract/Free Full Text]

Fainsod, A., Steinbeisser, H. and De Robertis, E. M (1994). On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J 13, 5015-5025.[Medline]

Fjose, A., Molven, A. and Eiken, H. G (1988). Molecular cloning and chracterization of homeobox-containing genes from Atlantic salmon. Gene 62, 141-152.[Medline]

Gont, L. K., Steinbeisser, H., Blumberg, B. and De Robertis, E. M (1993). Tail formation as a continuation of gastrulation: the multiple cell populations of the Xenopus tailbud derive from the late blastopore lip. Development 119, 991-1004.[Abstract]

Graff, J. M., Thies, R. S., Song, J. J., Celeste, A. J. and Melton, D. A (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.[Medline]

Grieder, N. C., Nellen, D., Burke, R., Basler, K. and Affolter, M (1995). schnurri is required for Drosophila dpp signalling and encodes a zinc finger protein similar to the mamalian transcription factor PRDII-BF1. Cell 81, 791-800.[Medline]

Gurdon, J. B (1992). The generation of diversity and pattern in animal development. Cell 68, 185-199.[Medline]

Harland, R. M (1991). In situ hybridization: an improved whole-mount method for Xenopus embryos. Meth. Cell Biol 36, 685-695.[Medline]

Harland, R. M (1994). The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducers. Proc. Natl Acad. Sci. USA 91, 10243-10246.[Free Full Text]

Holley, S. A., Jackson, P. D., Sasai, Y., Lu, B., De Robertis, E. M., Hoffmann, M. and Ferguson, E. L (1995). A conserved system for dorso-ventral patterning in insects and vertebrates involving sog and chordin. Nature 376, 249-253.[Medline]

Jagla, K., Stanceva, I., Dretzen, G., Bellard, F. and Bellard, M (1994). A distinct class of homeodomain proteins is encoded by two sequentially expressed Drosophila genes from 93D/E cluster. Nucleic Acids Res 22, 1202-1207.[Abstract/Free Full Text]

Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. and Hogan, B. L (1992). DVR-4 (bone morphogenetic protein-4). as a posterior-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.[Abstract]

Jones, C. M. and Smith, J. C (1995). Revolving vertebrates. Curr. Biol 5, 574-576.[Medline]

Kao, K. R. and Elinson, R. P (1988). The entire mesodermal mantle behaves as Spemann's organizer in dorsoanterior enhanced Xenopuslaevis embryos. Dev. Biol 127, 64-77.[Medline]

Kimelman, D., Christian, J. L. and Moon, R. T (1992). Synergistic principles of development: overlapping patterning systems in Xenopus mesoderm induction. Development 116, 1-9.[Abstract]

Kingsley, D. M (1994). The TGF-b superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 8, 133-146.[Free Full Text]

Koster, M., Plessow, S., Clement, J. H., Lorenz, A., Tiedemann, H. and Knochel, W (1991). Bone morphogenetic protein 4 (BMP-4), a member of the TGF-beta family, in early embryos of Xenopuslaevis : analysis of mesoderm inducing activity. Mech. Dev 33, 191-199.[Medline]

Lemaire, P., Garrett, N. and Gurdon, J. B (1995). Expression cloning of siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81, 85-94.[Medline]

McGinnis, W. and Krumlauf, R (1992). Homeobox genes and axial patterning. Cell 68, 283-302.[Medline]

Mohun, T. J., Brennan, S., Dathan, N., Fairman, S. and Gurdon, J. B (1984). Cell type-specific activation of actin genes in the early amphibian embryo. Nature 311, 716-721.[Medline]

Moody, S. A (1987). Fates of the blastomeres of the 32-cell-stage Xenopus embryo. Dev. Biol 122, 300-319.[Medline]

Niehrs, C. and De Robertis, E. M (1991). Ectopic expression of a homeobox gene changes cell fate in Xenopus embryos in a position-specific manner. EMBO J 10, 3621-3629.[Medline]

Niehrs, C., Keller, R., Cho, K. W. and De Robertis, E. M (1993). The homeobox gene goosecoid controls cell migration in Xenopus embryos. Cell 72, 491-503.[Medline]

Niehrs, C., Steinbeisser, H. and De Robertis, E. M (1994). Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid. Science 263, 817-820.[Abstract/Free Full Text]

Ruiz i Altaba, A. and Melton, D. A (1989). Bimodal and graded expression of the Xenopus homeobox gene Xhox3 during embryonic development. Development 106, 173-183.[Abstract]

Sanger, F., Nicklen, S. and Coulson, A. R (1977). DNA sequencing with chain-terminating inhibitors. Proc. Natl Acad. Sci. USA 74, 5436-5467.

Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. and De Robertis, E. M (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.[Medline]

Savage, C., Das, P., Finelli, A., Townsend, S., Sun, C.-Y., Baird, S. and Padgett, R (1996). Caenorhabditis elegans genes sma-2, sma-3 and sma-4define a conserved family of transforming growth factorpathway components. Proc. Natl Acad. Sci. USA 93, 790-794.[Abstract/Free Full Text]

Scharf, S. R. and Gerhart J. C (1983). Axis determination in eggs of Xenopus laevis : a critical period before first cleavage, identified by the common effects of cold, pressure and ultraviolet irradiation. Dev. Biol 99, 75-87.[Medline]

Schmidt, J. E., Suzuki, A., Ueno, N. and Kimelman, D (1995). Localized BMP-4 mediates dorsal/ventral patterning in the early Xenopus embryo. Dev. Biol 169, 37-50.[Medline]

Sekelsky, J. J., Newfeld, S. J., Raferty, L. A., Chartnoff, E. H. and Gelbart, W. M (1995). Genetic characterization and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophilamelanogaster. Genetics 139, 1347-1358.[Abstract]

Shimell, M. J., Ferguson, E. L., Childs, S. R. and O'Connor, M. B (1991). The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1. Cell 67, 469-481.[Medline]

Sive, H. L (1993). The frog prince-ss: a molecular formula for dorsoventral patterning in Xenopus. Genes Dev 7, 1-12.[Free Full Text]

Slack, J. M. W (1993). Embryonic induction. Mech. Dev 41, 91-107.[Medline]

Smith, J. C. and Slack, J. M (1983). Dorsalization and neural induction: properties of the organizer in Xenopuslaevis. J. Embryol. Exp. Morphol 78, 299-317.[Medline]

Steinbeisser, H., Fainsod, A, Niehrs, C., Sasai, Y. and De Robertis, E. M (1995). The role of gsc and BMP-4 in dorso ventral patterning of the marginal zone in Xenopus: a loss of function study using antisense RNA. EMBO J 14, 5230-5243.[Medline]

Suzuki, A., Thies, R. S., Yamaji, N., Song, J. J., Wozney, J. M., Murakami, K. and Ueno, N (1994). A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo. Proc. Natl Acad. Sci. USA 91, 10255-10259.[Abstract/Free Full Text]

Tiedemann, H., Tiedemann, H., Grunz, H. and Kn\232chel, W (1995). Molecular mechanisms of tissue determination and pattern formation in amphibian embryos. Naturwissenschaften 82, 123-134.[Medline]

von Dassow, G., Schmidt, J. E. and Kimelman, D (1993). Induction of the Xenopus organizer: expression and regulation of Xnot, a novel FGF and activin-regulated homeo box gene. Genes Dev 7, 355-366.[Abstract/Free Full Text]

Wilson, P. A. and Hemmati-Brivanlou (1995). Induction of epidermis and inhibition of neural cell fate by BMP-4. Nature 376, 331-333.[Medline]

Xu, R.-H., Dong, Z., Maeno, M., Kim, J., Suzuki, A., Ueno, N., Sredni, D., Colburn, N. H. and Kung, H.-F (1996). Involvement of ras/raf/AP1 in BMP-4 signalling during Xenopus embryonic development. Proc. Natl Acad. Sci. USA 93, 834-838.[Abstract/Free Full Text]

Papalopulu, N. and Kintner, C (1996). A Xenopus gene, Xbr-1, defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye. Dev. Biol 174, 104-114.[Medline]

Schmidt, J. E., von Dassow, G. and Kimelman, D (1996). Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox. Development 122, 1711-1721.[Abstract]

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J. Biol. Chem., September 1, 2000; 275(36): 27973 - 27978.
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				E. Amaya Xenomics Genome Res., December 1, 2005; 15(12): 1683 - 1691. [Abstract] [Full Text] [PDF]

				M. Matsuo-Takasaki, M. Matsumura, and Y. Sasai An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation Development, September 1, 2005; 132(17): 3885 - 3894. [Abstract] [Full Text] [PDF]

				U. J. Pyati, A. E. Webb, and D. Kimelman Transgenic zebrafish reveal stage-specific roles for Bmp signaling in ventral and posterior mesoderm development Development, May 15, 2005; 132(10): 2333 - 2343. [Abstract] [Full Text] [PDF]

				N. Offner, N. Duval, M. Jamrich, and B. Durand The pro-apoptotic activity of a vertebrate Bar-like homeobox gene plays a key role in patterning the Xenopus neural plate by limiting the number of chordin- and shh-expressing cells Development, April 15, 2005; 132(8): 1807 - 1818. [Abstract] [Full Text] [PDF]

				T. Koide, T. Hayata, and K. W. Y. Cho Gene Regulatory Networks Special Feature: Xenopus as a model system to study transcriptional regulatory networks PNAS, April 5, 2005; 102(14): 4943 - 4948. [Abstract] [Full Text] [PDF]

				J. Tao, E. Kuliyev, X. Wang, X. Li, T. Wilanowski, S. M. Jane, P. E. Mead, and J. M. Cunningham BMP4-dependent expression of Xenopus Grainyhead-like 1 is essential for epidermal differentiation Development, March 1, 2005; 132(5): 1021 - 1034. [Abstract] [Full Text] [PDF]

				Y. Cao, S. Knochel, C. Donow, J. Miethe, E. Kaufmann, and W. Knochel The POU Factor Oct-25 Regulates the Xvent-2B Gene and Counteracts Terminal Differentiation in Xenopus Embryos J. Biol. Chem., October 15, 2004; 279(42): 43735 - 43743. [Abstract] [Full Text] [PDF]

				M.-C. Ramel and A. C. Lekven Repression of the vertebrate organizer by Wnt8 is mediated by Vent and Vox Development, August 15, 2004; 131(16): 3991 - 4000. [Abstract] [Full Text] [PDF]

				H.-T. Tseng, R. Shah, and M. Jamrich Function and regulation of FoxF1 during Xenopus gut development Development, August 1, 2004; 131(15): 3637 - 3647. [Abstract] [Full Text] [PDF]

				C. Tribulo, M. J. Aybar, V. H. Nguyen, M. C. Mullins, and R. Mayor Regulation of Msx genes by a Bmp gradient is essential for neural crest specification Development, December 29, 2003; 130(26): 6441 - 6452. [Abstract] [Full Text] [PDF]

				J. Yang, J. Wu, C. Tan, and P. S. Klein PP2A:B56{epsilon} is required for Wnt/{beta}-catenin signaling during embryonic development Development, December 1, 2003; 130(23): 5569 - 5578. [Abstract] [Full Text] [PDF]

				I. L. Blitz, K. W. Y. Cho, and C. Chang Twisted gastrulation loss-of-function analyses support its role as a BMP inhibitor during early Xenopus embryogenesis Development, October 15, 2003; 130(20): 4975 - 4988. [Abstract] [Full Text] [PDF]

				T. Leung, J. Bischof, I. Soll, D. Niessing, D. Zhang, J. Ma, H. Jackle, and W. Driever bozozok directly represses bmp2b transcription and mediates the earliest dorsoventral asymmetry of bmp2b expression in zebrafish Development, August 15, 2003; 130(16): 3639 - 3649. [Abstract] [Full Text] [PDF]

				M. Polli and E. Amaya A study of mesoderm patterning through the analysis of the regulation of Xmyf-5 expression Development, March 8, 2003; 129(12): 2917 - 2927. [Abstract] [Full Text] [PDF]

				S. Shim, N. Bae, and J.-K. Han Bone morphogenetic protein-4-induced activation of Xretpos is mediated by Smads and Olf-1/EBF associated zinc finger (OAZ) Nucleic Acids Res., July 15, 2002; 30(14): 3107 - 3117. [Abstract] [Full Text] [PDF]

				H. Friedle and W. Knochel Cooperative Interaction of Xvent-2 and GATA-2 in the Activation of the Ventral Homeobox Gene Xvent-1B J. Biol. Chem., June 21, 2002; 277(26): 23872 - 23881. [Abstract] [Full Text] [PDF]

				C. Ring, S. Ogata, L. Meek, J. Song, T. Ohta, K. Miyazono, and K. W.Y. Cho The role of a Williams-Beuren syndrome-associated helix-loop-helix domain-containing transcription factor in activin/nodal signaling Genes & Dev., April 1, 2002; 16(7): 820 - 835. [Abstract] [Full Text] [PDF]

				Y. Miyanaga, I. Torregroza, and T. Evans A Maternal Smad Protein Regulates Early Embryonic Apoptosis in Xenopus laevis Mol. Cell. Biol., March 1, 2002; 22(5): 1317 - 1328. [Abstract] [Full Text] [PDF]

				K. O. Hartley, S. L. Nutt, and E. Amaya Targeted gene expression in transgenic Xenopus using the binary Gal4-UAS system PNAS, January 24, 2002; (2002) 22646899. [Abstract] [Full Text] [PDF]

				T. S. Yamamoto, C. Takagi, A. C. Hyodo, and N. Ueno Suppression of head formation by Xmsx-1 through the inhibition of intracellular nodal signaling Development, July 15, 2001; 128(14): 2769 - 2779. [Abstract] [Full Text] [PDF]

				Y. Imai, M. A. Gates, A. E. Melby, D. Kimelman, A. F. Schier, and W. S. Talbot The homeobox genes vox and vent are redundant repressors of dorsal fates in zebrafish Development, June 15, 2001; 128(12): 2407 - 2420. [Abstract] [Full Text] [PDF]

				T. R. Clarke, Y. Hoshiya, S. E. Yi, X. Liu, K. M. Lyons, and P. K. Donahoe Mullerian Inhibiting Substance Signaling Uses a Bone Morphogenetic Protein (BMP)-Like Pathway Mediated by ALK2 and Induces Smad6 Expression Mol. Endocrinol., June 1, 2001; 15(6): 946 - 959. [Abstract] [Full Text] [PDF]

				K. L. Rossow and R. Janknecht The Ewing's Sarcoma Gene Product Functions as a Transcriptional Activator Cancer Res., March 1, 2001; 61(6): 2690 - 2695. [Abstract] [Full Text]

				M. Kuhl, L. C. Sheldahl, C. C. Malbon, and R. T. Moon Ca2+/Calmodulin-dependent Protein Kinase II Is Stimulated by Wnt and Frizzled Homologs and Promotes Ventral Cell Fates in Xenopus J. Biol. Chem., April 21, 2000; 275(17): 12701 - 12711. [Abstract] [Full Text] [PDF]

				O Kazanskaya, A Glinka, and C Niehrs The role of Xenopus dickkopf1 in prechordal plate specification and neural patterning Development, January 11, 2000; 127(22): 4981 - 4992. [Abstract] [PDF]

				R Vignali, L Poggi, F Madeddu, and G Barsacchi HNF1(beta) is required for mesoderm induction in the Xenopus embryo Development, January 4, 2000; 127(7): 1455 - 1465. [Abstract] [PDF]

				A. M. Barbieri, G. Lupo, A. Bulfone, M. Andreazzoli, M. Mariani, F. Fougerousse, G. G. Consalez, G. Borsani, J. S. Beckmann, G. Barsacchi, et al. A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis PNAS, September 14, 1999; 96(19): 10729 - 10734. [Abstract] [Full Text] [PDF]