The SH2-containing tyrosine phosphatase corkscrew is required during signaling by sevenless, Ras1 and Raf

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				L. A. Jarvis, S. J. Toering, M. A. Simon, M. A. Krasnow, and R. K. Smith-Bolton Sprouty proteins are in vivo targets of Corkscrew/SHP-2 tyrosine phosphatases Development, March 15, 2006; 133(6): 1133 - 1142. [Abstract] [Full Text] [PDF]

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				R. Wilson, A. Battersby, A. Csiszar, E. Vogelsang, and M. Leptin A Functional Domain of Dof That Is Required for Fibroblast Growth Factor Signaling Mol. Cell. Biol., March 15, 2004; 24(6): 2263 - 2276. [Abstract] [Full Text] [PDF]

				Y. M. Agazie and M. J. Hayman Development of an Efficient "Substrate-trapping" Mutant of Src Homology Phosphotyrosine Phosphatase 2 and Identification of the Epidermal Growth Factor Receptor, Gab1, and Three Other Proteins as Target Substrates J. Biol. Chem., April 11, 2003; 278(16): 13952 - 13958. [Abstract] [Full Text] [PDF]

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				I. Wolf, B. J. Jenkins, Y. Liu, M. Seiffert, J. M. Custodio, P. Young, and L. R. Rohrschneider Gab3, a New DOS/Gab Family Member, Facilitates Macrophage Differentiation Mol. Cell. Biol., January 1, 2002; 22(1): 231 - 244. [Abstract] [Full Text] [PDF]

				R. K. Smith, P. M. Carroll, J. D. Allard, and M. A. Simon MASK, a large ankyrin repeat and KH domain-containing protein involved in Drosophila receptor tyrosine kinase signaling Development, January 1, 2002; 129(1): 71 - 82. [Abstract] [Full Text] [PDF]

				J. L. Schutzman, C. Z. Borland, J. C. Newman, M. K. Robinson, M. Kokel, and M. J. Stern The Caenorhabditis elegans EGL-15 Signaling Pathway Implicates a DOS-Like Multisubstrate Adaptor Protein in Fibroblast Growth Factor Signal Transduction Mol. Cell. Biol., December 1, 2001; 21(23): 8104 - 8116. [Abstract] [Full Text] [PDF]

				M. R. J. Hamlet and L. A. Perkins Analysis of Corkscrew Signaling in the Drosophila Epidermal Growth Factor Receptor Pathway During Myogenesis Genetics, November 1, 2001; 159(3): 1073 - 1087. [Abstract] [Full Text] [PDF]

				J. Lorenzen, S. Baker, F Denhez, M. Melnick, D. Brower, and L. Perkins Nuclear import of activated D-ERK by DIM-7, an importin family member encoded by the gene moleskin Development, January 4, 2001; 128(8): 1403 - 1414. [Abstract] [PDF]

				C. R. Maroun, M. A. Naujokas, M. Holgado-Madruga, A. J. Wong, and M. Park The Tyrosine Phosphatase SHP-2 Is Required for Sustained Activation of Extracellular Signal-Regulated Kinase and Epithelial Morphogenesis Downstream from the Met Receptor Tyrosine Kinase Mol. Cell. Biol., November 15, 2000; 20(22): 8513 - 8525. [Abstract] [Full Text]

				L. Firth, J. Manchester, J. A. Lorenzen, M. Baron, and L. A. Perkins Identification of Genomic Regions That Interact With a Viable Allele of the Drosophila Protein Tyrosine Phosphatase Corkscrew Genetics, October 1, 2000; 156(2): 733 - 748. [Abstract] [Full Text]

				Z.-Q. Shi, D.-H. Yu, M. Park, M. Marshall, and G.-S. Feng Molecular Mechanism for the Shp-2 Tyrosine Phosphatase Function in Promoting Growth Factor Stimulation of Erk Activity Mol. Cell. Biol., March 1, 2000; 20(5): 1526 - 1536. [Abstract] [Full Text]

				K. Fukunaga, T. Noguchi, H. Takeda, T. Matozaki, Y. Hayashi, H. Itoh, and M. Kasuga Requirement for Protein-tyrosine Phosphatase SHP-2 in Insulin-induced Activation of c-Jun NH2-terminal Kinase J. Biol. Chem., February 18, 2000; 275(7): 5208 - 5213. [Abstract] [Full Text] [PDF]

				A. M. O'Reilly, S. Pluskey, S. E. Shoelson, and B. G. Neel Activated Mutants of SHP-2 Preferentially Induce Elongation of Xenopus Animal Caps Mol. Cell. Biol., January 1, 2000; 20(1): 299 - 311. [Abstract] [Full Text]

				K. P. White, S. A. Rifkin, P. Hurban, and D. S. Hogness Microarray Analysis of Drosophila Development During Metamorphosis Science, December 10, 1999; 286(5447): 2179 - 2184. [Abstract] [Full Text]

				C.-K. Qu, W.-M. Yu, B. Azzarelli, and G.-S. Feng Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals PNAS, July 20, 1999; 96(15): 8528 - 8533. [Abstract] [Full Text] [PDF]

				E.-S. Oh, H. Gu, T. M. Saxton, J. F. Timms, S. Hausdorff, E. U. Frevert, B. B. Kahn, T. Pawson, B. G. Neel, and S. M. Thomas Regulation of Early Events in Integrin Signaling by Protein Tyrosine Phosphatase SHP-2 Mol. Cell. Biol., April 1, 1999; 19(4): 3205 - 3215. [Abstract] [Full Text] [PDF]

				S Kramer, M Okabe, N Hacohen, M. Krasnow, and Y Hiromi Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila Development, January 6, 1999; 126(11): 2515 - 2525. [Abstract] [PDF]

				D.-H. Yu, C.-K. Qu, O. Henegariu, X. Lu, and G.-S. Feng Protein-tyrosine Phosphatase Shp-2 Regulates Cell Spreading, Migration, and Focal Adhesion J. Biol. Chem., August 14, 1998; 273(33): 21125 - 21131. [Abstract] [Full Text] [PDF]

				N. Le and M. A. Simon Disabled Is a Putative Adaptor Protein That Functions during Signaling by the Sevenless Receptor Tyrosine Kinase Mol. Cell. Biol., August 1, 1998; 18(8): 4844 - 4854. [Abstract] [Full Text]

				K. Nakamura and J. C. Cambier B Cell Antigen Receptor (BCR)-Mediated Formation of a SHP-2-pp120 Complex and Its Inhibition by Fe{gamma}RIIB1-BCR Coligation J. Immunol., July 15, 1998; 161(2): 684 - 691. [Abstract] [Full Text] [PDF]

				T. B. Deb, L. Wong, D. S. Salomon, G. Zhou, J. E. Dixon, J. S. Gutkind, S. A. Thompson, and G. R. Johnson A Common Requirement for the Catalytic Activity and Both SH2 Domains of SHP-2 in Mitogen-activated Protein (MAP) Kinase Activation by the ErbB Family of Receptors. A SPECIFIC ROLE FOR SHP-2 IN MAP, BUT NOT c-Jun AMINO-TERMINAL KINASE ACTIVATION J. Biol. Chem., July 3, 1998; 273(27): 16643 - 16646. [Abstract] [Full Text] [PDF]

				J. D. Allard, R. Herbst, P. M. Carroll, and M. A. Simon Mutational Analysis of the SRC Homology 2�Domain Protein-tyrosine Phosphatase Corkscrew J. Biol. Chem., May 22, 1998; 273(21): 13129 - 13135. [Abstract] [Full Text] [PDF]

				M. Tsuda, T. Matozaki, K. Fukunaga, Y. Fujioka, A. Imamoto, T. Noguchi, T. Takada, T. Yamao, H. Takeda, F. Ochi, et al. Integrin-mediated Tyrosine Phosphorylation of SHPS-1 and Its Association with SHP-2. ROLES OF Fak AND Src FAMILY KINASES J. Biol. Chem., May 22, 1998; 273(21): 13223 - 13229. [Abstract] [Full Text] [PDF]

				T. Takada, T. Matozaki, H. Takeda, K. Fukunaga, T. Noguchi, Y. Fujioka, I. Okazaki, M. Tsuda, T. Yamao, F. Ochi, et al. Roles of the Complex Formation of SHPS-1 with SHP-2 in Insulin-stimulated Mitogen-activated Protein Kinase Activation J. Biol. Chem., April 10, 1998; 273(15): 9234 - 9242. [Abstract] [Full Text] [PDF]

				M. J. Gutch, A. J. Flint, J. Keller, N. K. Tonks, and M. O. Hengartner The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval�development Genes & Dev., February 15, 1998; 12(4): 571 - 585. [Abstract] [Full Text]

				Z. Yu, L. Su, O. Hoglinger, M. L. Jaramillo, D. Banville, and S.-H. Shen SHP-1 Associates with Both Platelet-derived Growth Factor Receptor and the p85 Subunit of Phosphatidylinositol 3-Kinase J. Biol. Chem., February 6, 1998; 273(6): 3687 - 3694. [Abstract] [Full Text] [PDF]

				P Towb, R. Galindo, and S. Wasserman Recruitment of Tube and Pelle to signaling sites at the surface of the Drosophila embryo Development, January 7, 1998; 125(13): 2443 - 2450. [Abstract] [PDF]