A mutational analysis of the 5' HoxD genes: dissection of genetic interactions during limb development in the mouse

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				O. Cocquempot, V. Brault, C. Babinet, and Y. Herault Fork Stalling and Template Switching As a Mechanism for Polyalanine Tract Expansion Affecting the DYC Mutant of HOXD13, a New Murine Model of Synpolydactyly Genetics, September 1, 2009; 183(1): 23 - 30. [Abstract] [Full Text] [PDF]

				Z. Wang, L. Yuan, S. J. Rossiter, X. Zuo, B. Ru, H. Zhong, N. Han, G. Jones, P. D. Jepson, and S. Zhang Adaptive Evolution of 5'HoxD Genes in the Origin and Diversification of the Cetacean Flipper Mol. Biol. Evol., March 1, 2009; 26(3): 613 - 622. [Abstract] [Full Text] [PDF]

				Y. Kawakami, Y. Uchiyama, C. Rodriguez Esteban, T. Inenaga, N. Koyano-Nakagawa, H. Kawakami, M. Marti, M. Kmita, P. Monaghan-Nichols, R. Nishinakamura, et al. Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities Development, February 15, 2009; 136(4): 585 - 594. [Abstract] [Full Text] [PDF]

				R. Raz, S. Stricker, E. Gazzerro, J. L. Clor, F. Witte, H. Nistala, S. Zabski, R. C. Pereira, L. Stadmeyer, X. Wang, et al. The mutation ROR2W749X, linked to human BDB, is a recessive mutation in the mouse, causing brachydactyly, mediating patterning of joints and modeling recessive Robinow syndrome Development, May 1, 2008; 135(9): 1713 - 1723. [Abstract] [Full Text] [PDF]

				W. M. Knosp, C. Saneyoshi, S. Shou, H. P. Bachinger, and H. S. Stadler Elucidation, Quantitative Refinement, and in Vivo Utilization of the HOXA13 DNA Binding Site J. Biol. Chem., March 2, 2007; 282(9): 6843 - 6853. [Abstract] [Full Text] [PDF]

				R. S. Hawley and W. D. Gilliland Sometimes the Result Is Not the Answer: The Truths and the Lies That Come From Using the Complementation Test Genetics, September 1, 2006; 174(1): 5 - 15. [Abstract] [Full Text] [PDF]

				T. D. Capellini, G. Di Giacomo, V. Salsi, A. Brendolan, E. Ferretti, D. Srivastava, V. Zappavigna, and L. Selleri Pbx1/Pbx2 requirement for distal limb patterning is mediated by the hierarchical control of Hox gene spatial distribution and Shh expression Development, June 1, 2006; 133(11): 2263 - 2273. [Abstract] [Full Text] [PDF]

				B Dlugaszewska, A Silahtaroglu, C Menzel, S Kubart, M Cohen, S Mundlos, Z Tumer, K Kjaer, U Friedrich, H-H Ropers, et al. Breakpoints around the HOXD cluster result in various limb malformations J. Med. Genet., February 1, 2006; 43(2): 111 - 118. [Abstract] [Full Text] [PDF]

				C. Li, X. Xu, D. K. Nelson, T. Williams, M. R. Kuehn, and C.-X. Deng FGFR1 function at the earliest stages of mouse limb development plays an indispensable role in subsequent autopod morphogenesis Development, November 1, 2005; 132(21): 4755 - 4764. [Abstract] [Full Text] [PDF]

				A. R. Kumar, W. A. Hudson, W. Chen, R. Nishiuchi, Q. Yao, and J. H. Kersey Hoxa9 influences the phenotype but not the incidence of Mll-AF9 fusion gene leukemia Blood, March 1, 2004; 103(5): 1823 - 1828. [Abstract] [Full Text] [PDF]

				H. Lavoie, F. Debeane, Q.-D. Trinh, J.-F. Turcotte, L.-P. Corbeil-Girard, M.-J. Dicaire, A. Saint-Denis, M. Page, G. A. Rouleau, and B. Brais Polymorphism, shared functions and convergent evolution of genes with sequences coding for polyalanine domains Hum. Mol. Genet., November 15, 2003; 12(22): 2967 - 2979. [Abstract] [Full Text] [PDF]

				P Debeer, C Bacchelli, P J Scambler, L De Smet, J-P Fryns, and F R Goodman Severe digital abnormalities in a patient heterozygous for both a novel missense mutation in HOXD13 and a polyalanine tract expansion in HOXA13 J. Med. Genet., November 1, 2002; 39(11): 852 - 856. [Full Text] [PDF]

				F. Spitz, F. Gonzalez, C. Peichel, T. F. Vogt, D. Duboule, and J. Zakany Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations Genes & Dev., September 1, 2001; 15(17): 2209 - 2214. [Abstract] [Full Text] [PDF]

				E van Den Akker, C Fromental-Ramain, W de Graaff, H Le Mouellic, P Brulet, P Chambon, and J Deschamps Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes Development, January 5, 2001; 128(10): 1911 - 1921. [Abstract] [PDF]

				A. Faiella, M. Wernig, G. G. Consalez, U. Hostick, C. Hofmann, E. Hustert, E. Boncinelli, R. Balling, and J. H. Nadeau A mouse model for valproate teratogenicity: parental effects, homeotic transformations, and altered HOX expression Hum. Mol. Genet., January 22, 2000; 9(2): 227 - 236. [Abstract] [Full Text] [PDF]

				F. Chen and M. R. Capecchi Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy PNAS, January 19, 1999; 96(2): 541 - 546. [Abstract] [Full Text] [PDF]

				Y. G. Yueh, D. P. Gardner, and C. Kappen Evidence for regulation of cartilage differentiation by the homeobox gene Hoxc-8 PNAS, August 18, 1998; 95(17): 9956 - 9961. [Abstract] [Full Text] [PDF]

				L. J. Brunet, J. A. McMahon, A. P. McMahon, and R. M. Harland Noggin, Cartilage Morphogenesis, and Joint Formation in the Mammalian Skeleton Science, May 29, 1998; 280(5368): 1455 - 1457. [Abstract] [Full Text]

				Y Herault, J Beckers, T Kondo, N Fraudeau, and D Duboule Genetic analysis of a Hoxd-12 regulatory element reveals global versus local modes of controls in the HoxD complex Development, January 5, 1998; 125(9): 1669 - 1677. [Abstract] [PDF]

				D. Duboule Hox is in the hair: a break in�colinearity? Genes & Dev., January 1, 1998; 12(1): 1 - 4. [Full Text]

				T Takagi, H Moribe, H Kondoh, and Y Higashi DeltaEF1, a zinc finger and homeodomain transcription factor, is required for skeleton patterning in multiple lineages Development, January 1, 1998; 125(1): 21 - 31. [Abstract] [PDF]

				J. Zakany, C. Fromental-Ramain, X. Warot, and D. Duboule Regulation of number and size of digits by posterior Hox genes: A dose-dependent mechanism with potential evolutionary�implications PNAS, December 9, 1997; 94(25): 13695 - 13700. [Abstract] [Full Text] [PDF]

				F. R. Goodman, S. Mundlos, Y. Muragaki, D. Donnai, M. L. Giovannucci-Uzielli, E. Lapi, F. Majewski, J. McGaughran, C. McKeown, W. Reardon, et al. Synpolydactyly phenotypes correlate with size of expansions in HOXD13 polyalanine�tract PNAS, July 8, 1997; 94(14): 7458 - 7463. [Abstract] [Full Text] [PDF]

				X Warot, C Fromental-Ramain, V Fraulob, P Chambon, and P Dolle Gene dosage-dependent effects of the Hoxa-13 and Hoxd-13 mutations on morphogenesis of the terminal parts of the digestive and urogenital tracts Development, January 12, 1997; 124(23): 4781 - 4791. [Abstract] [PDF]

				E. Carpenter, J. Goddard, A. Davis, T. Nguyen, and M. Capecchi Targeted disruption of Hoxd-10 affects mouse hindlimb development Development, January 11, 1997; 124(22): 4505 - 4514. [Abstract] [PDF]

				V Knezevic, R De Santo, K Schughart, U Huffstadt, C Chiang, K. Mahon, and S Mackem Hoxd-12 differentially affects preaxial and postaxial chondrogenic branches in the limb and regulates Sonic hedgehog in a positive feedback loop Development, January 11, 1997; 124(22): 4523 - 4536. [Abstract] [PDF]

				C. Peichel, B Prabhakaran, and T. Vogt The mouse Ulnaless mutation deregulates posterior HoxD gene expression and alters appendicular patterning Development, January 9, 1997; 124(18): 3481 - 3492. [Abstract] [PDF]

				Y Herault, N Fraudeau, J Zakany, and D Duboule Ulnaless (Ul), a regulatory mutation inducing both loss-of-function and gain-of-function of posterior Hoxd genes Development, January 9, 1997; 124(18): 3493 - 3500. [Abstract] [PDF]

				H. Lu, J. Revelli, L Goering, C Thaller, and G Eichele Retinoid signaling is required for the establishment of a ZPA and for the expression of Hoxb-8, a mediator of ZPA formation Development, January 5, 1997; 124(9): 1643 - 1651. [Abstract] [PDF]

				D. Goff and C. Tabin Analysis of Hoxd-13 and Hoxd-11 misexpression in chick limb buds reveals that Hox genes affect both bone condensation and growth Development, January 2, 1997; 124(3): 627 - 636. [Abstract] [PDF]