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T.-a. Matsuoka, I. Artner, E. Henderson, A. Means, M. Sander, and R. Stein The MafA transcription factor appears to be responsible for tissue-specific expression of insulin PNAS, March 2, 2004; 101(9): 2930 - 2933. [Abstract] [Full Text] [PDF] |
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H. Yoshitomi and K. S. Zaret Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a Development, February 15, 2004; 131(4): 807 - 817. [Abstract] [Full Text] [PDF] |
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S. B. Smith, H. Watada, and M. S. German Neurogenin3 Activates the Islet Differentiation Program while Repressing Its Own Expression Mol. Endocrinol., January 1, 2004; 18(1): 142 - 149. [Abstract] [Full Text] [PDF] |
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I. Ber, K. Shternhall, S. Perl, Z. Ohanuna, I. Goldberg, I. Barshack, L. Benvenisti-Zarum, I. Meivar-Levy, and S. Ferber Functional, Persistent, and Extended Liver to Pancreas Transdifferentiation J. Biol. Chem., August 22, 2003; 278(34): 31950 - 31957. [Abstract] [Full Text] [PDF] |
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B. Duvillie, M. Attali, V. Aiello, E. Quemeneur, and R. Scharfmann Label-Retaining Cells in the Rat Pancreas: Location and Differentiation Potential in Vitro Diabetes, August 1, 2003; 52(8): 2035 - 2042. [Abstract] [Full Text] [PDF] |
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P. Blyszczuk, J. Czyz, G. Kania, M. Wagner, U. Roll, L. St-Onge, and A. M. Wobus Expression of Pax4 in embryonic stem cells promotes differentiation of nestin-positive progenitor and insulin-producing cells PNAS, February 4, 2003; 100(3): 998 - 1003. [Abstract] [Full Text] [PDF] |
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D. Melloul, S. Marshak, and E. Cerasi Regulation of pdx-1 Gene Expression Diabetes, December 1, 2002; 51(90003): S320 - 325. [Abstract] [Full Text] [PDF] |
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Y. Kido, J. Nakae, M. L. Hribal, S. Xuan, A. Efstratiadis, and D. Accili Effects of Mutations in the Insulin-like Growth Factor Signaling System on Embryonic Pancreas Development and beta -Cell Compensation to Insulin Resistance J. Biol. Chem., September 20, 2002; 277(39): 36740 - 36747. [Abstract] [Full Text] [PDF] |
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A. M. Holland, M. A. Hale, H. Kagami, R. E. Hammer, and R. J. MacDonald Experimental control of pancreatic development and maintenance PNAS, September 17, 2002; 99(19): 12236 - 12241. [Abstract] [Full Text] [PDF] |
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H. Kaneto, G. Xu, N. Fujii, S. Kim, S. Bonner-Weir, and G. C. Weir Involvement of c-Jun N-terminal Kinase in Oxidative Stress-mediated Suppression of Insulin Gene Expression J. Biol. Chem., August 9, 2002; 277(33): 30010 - 30018. [Abstract] [Full Text] [PDF] |
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C. S. Lee, N. J. Sund, M. Z. Vatamaniuk, F. M. Matschinsky, D. A. Stoffers, and K. H. Kaestner Foxa2 Controls Pdx1 Gene Expression in Pancreatic {beta}-Cells In Vivo Diabetes, August 1, 2002; 51(8): 2546 - 2551. [Abstract] [Full Text] [PDF] |
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M. Olbrot, J. Rud, L. G. Moss, and A. Sharma Identification of beta -cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA PNAS, May 14, 2002; 99(10): 6737 - 6742. [Abstract] [Full Text] [PDF] |
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J. Sharpe, U. Ahlgren, P. Perry, B. Hill, A. Ross, J. Hecksher-Sorensen, R. Baldock, and D. Davidson Optical Projection Tomography as a Tool for 3D Microscopy and Gene Expression Studies Science, April 19, 2002; 296(5567): 541 - 545. [Abstract] [Full Text] [PDF] |
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H. Kaneto, A. Sharma, K. Suzuma, D. R. Laybutt, G. Xu, S. Bonner-Weir, and G. C. Weir Induction of c-Myc Expression Suppresses Insulin Gene Transcription by Inhibiting NeuroD/BETA2-mediated Transcriptional Activation J. Biol. Chem., April 5, 2002; 277(15): 12998 - 13006. [Abstract] [Full Text] [PDF] |
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M. Brissova, M. Shiota, W. E. Nicholson, M. Gannon, S. M. Knobel, D. W. Piston, C. V. E. Wright, and A. C. Powers Reduction in Pancreatic Transcription Factor PDX-1 Impairs Glucose-stimulated Insulin Secretion J. Biol. Chem., March 22, 2002; 277(13): 11225 - 11232. [Abstract] [Full Text] [PDF] |
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A. Bhushan, N. Itoh, S. Kato, J. P. Thiery, P. Czernichow, S. Bellusci, and R. Scharfmann Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis Development, December 15, 2001; 128(24): 5109 - 5117. [Abstract] [Full Text] [PDF] |
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K. Gerrish, M. A. Cissell, and R. Stein The Role of Hepatic Nuclear Factor 1alpha and PDX-1 in Transcriptional Regulation of the pdx-1 Gene J. Biol. Chem., December 14, 2001; 276(51): 47775 - 47784. [Abstract] [Full Text] [PDF] |
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S. K. Kim and M. Hebrok Intercellular signals regulating pancreas development and function Genes & Dev., January 15, 2001; 15(2): 111 - 127. [Full Text] |
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G Deutsch, J Jung, M Zheng, J Lora, and K. Zaret A bipotential precursor population for pancreas and liver within the embryonic endoderm Development, January 3, 2001; 128(6): 871 - 881. [Abstract] [PDF] |
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S. Marshak, E. Benshushan, M. Shoshkes, L. Havin, E. Cerasi, and D. Melloul Functional Conservation of Regulatory Elements in the pdx-1 Gene: PDX-1 and Hepatocyte Nuclear Factor 3beta Transcription Factors Mediate beta -Cell-Specific Expression Mol. Cell. Biol., October 15, 2000; 20(20): 7583 - 7590. [Abstract] [Full Text] |
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H.-P. Huang, M. Liu, H. M. El-Hodiri, K. Chu, M. Jamrich, and M.-J. Tsai Regulation of the Pancreatic Islet-Specific Gene BETA2 (neuroD) by Neurogenin 3 Mol. Cell. Biol., May 1, 2000; 20(9): 3292 - 3307. [Abstract] [Full Text] |
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L. Zhao, M. A. Cissell, E. Henderson, R. Colbran, and R. Stein The RIPE3b1 Activator of the Insulin Gene Is Composed of a Protein(s) of Approximately 43 kDa, Whose DNA Binding Activity Is Inhibited by Protein Phosphatase Treatment J. Biol. Chem., March 31, 2000; 275(14): 10532 - 10537. [Abstract] [Full Text] [PDF] |
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G. Gradwohl, A. Dierich, M. LeMeur, and F. Guillemot neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas PNAS, February 15, 2000; 97(4): 1607 - 1611. [Abstract] [Full Text] [PDF] |
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K. Gerrish, M. Gannon, D. Shih, E. Henderson, M. Stoffel, C. V. E. Wright, and R. Stein Pancreatic beta Cell-specific Transcription of the pdx-1 Gene. THE ROLE OF CONSERVED UPSTREAM CONTROL REGIONS AND THEIR HEPATIC NUCLEAR FACTOR 3beta SITES J. Biol. Chem., February 4, 2000; 275(5): 3485 - 3492. [Abstract] [Full Text] [PDF] |
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K. Ohneda, R. G. Mirmira, J. Wang, J. D. Johnson, and M. S. German The Homeodomain of PDX-1 Mediates Multiple Protein-Protein Interactions in the Formation of a Transcriptional Activation Complex on the Insulin Promoter Mol. Cell. Biol., February 1, 2000; 20(3): 900 - 911. [Abstract] [Full Text] |
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P. Miettinen, M Huotari, T Koivisto, J Ustinov, J Palgi, S Rasilainen, E Lehtonen, J Keski-Oja, and T Otonkoski Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors Development, January 6, 2000; 127(12): 2617 - 2627. [Abstract] [PDF] |
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S. B. Smith, H. C. Ee, J. R. Conners, and M. S. German Paired-Homeodomain Transcription Factor PAX4 Acts as a Transcriptional Repressor in Early Pancreatic Development Mol. Cell. Biol., December 1, 1999; 19(12): 8272 - 8280. [Abstract] [Full Text] [PDF] |
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U. Ahlgren, J. Jonsson, L. Jonsson, K. Simu, and H. Edlund beta -Cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta -cell phenotype and maturity onset diabetes Genes & Dev., June 15, 1998; 12(12): 1763 - 1768. [Abstract] [Full Text] |
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A. Øster, J. Jensen, P. Serup, P. Galante, O. D. Madsen, and L.-I. Larsson Rat Endocrine Pancreatic Development in Relation to Two Homeobox Gene Products (Pdx-1 and Nkx 6.1) J. Histochem. Cytochem., June 1, 1998; 46(6): 707 - 716. [Abstract] [Full Text] |
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M. Hebrok, S. K. Kim, and D. A. Melton Notochord repression of endodermal Sonic hedgehog permits pancreas development Genes & Dev., June 1, 1998; 12(11): 1705 - 1713. [Abstract] [Full Text] |
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W. M. Milewski, S. J. Duguay, S. J. Chan, and D. F. Steiner Conservation of PDX-1 Structure, Function, and Expression in Zebrafish Endocrinology, March 1, 1998; 139(3): 1440 - 1449. [Abstract] [Full Text] [PDF] |
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F Miralles, P Czernichow, and R Scharfmann Follistatin regulates the relative proportions of endocrine versus exocrine tissue during pancreatic development Development, January 3, 1998; 125(6): 1017 - 1024. [Abstract] [PDF] |
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R. Awatramani, S. Scherer, J. Grinspan, E. Collarini, R. Skoff, D. O'Hagan, J. Garbern, and J. Kamholz Evidence That the Homeodomain Protein Gtx Is Involved in the Regulation of Oligodendrocyte Myelination J. Neurosci., September 1, 1997; 17(17): 6657 - 6668. [Abstract] [Full Text] [PDF] |
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M Sander, A Neubuser, J Kalamaras, H C Ee, G R Martin, and M S German Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development. Genes & Dev., July 1, 1997; 11(13): 1662 - 1673. [Abstract] [PDF] |
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S. Kim, M Hebrok, and D. Melton Notochord to endoderm signaling is required for pancreas development Development, January 11, 1997; 124(21): 4243 - 4252. [Abstract] [PDF] |
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S.K. Kim, M. Hebrok, and D.A. Melton Pancreas Development in the Chick Embryo Cold Spring Harb Symp Quant Biol, January 1, 1997; 62(0): 377 - 383. [Abstract] [PDF] |
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R. H. Harrington and A. Sharma Transcription Factors Recognizing Overlapping C1-A2 Binding Sites Positively Regulate Insulin Gene Expression J. Biol. Chem., January 5, 2001; 276(1): 104 - 113. [Abstract] [Full Text] [PDF] |
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E. Ben-Shushan, S. Marshak, M. Shoshkes, E. Cerasi, and D. Melloul A Pancreatic beta -Cell-specific Enhancer in the Human PDX-1 Gene Is Regulated by Hepatocyte Nuclear Factor 3beta (HNF-3beta ), HNF-1alpha , and SPs Transcription Factors J. Biol. Chem., May 11, 2001; 276(20): 17533 - 17540. [Abstract] [Full Text] [PDF] |
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