Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development

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				K.-Q. Gong, A. R. Yallowitz, H. Sun, G. R. Dressler, and D. M. Wellik A Hox-Eya-Pax Complex Regulates Early Kidney Developmental Gene Expression Mol. Cell. Biol., November 1, 2007; 27(21): 7661 - 7668. [Abstract] [Full Text] [PDF]

				I. J. Murawski, D. B. Myburgh, J. Favor, and I. R. Gupta Vesico-ureteric reflux and urinary tract development in the Pax21Neu+/ mouse Am J Physiol Renal Physiol, November 1, 2007; 293(5): F1736 - F1745. [Abstract] [Full Text] [PDF]

				O. Michos, A. Goncalves, J. Lopez-Rios, E. Tiecke, F. Naillat, K. Beier, A. Galli, S. Vainio, and R. Zeller Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis Development, July 1, 2007; 134(13): 2397 - 2405. [Abstract] [Full Text] [PDF]

				J. C. Clarke, S. R. Patel, R. M. Raymond Jr, S. Andrew, B. G. Robinson, G. R. Dressler, and P. D. Brophy Regulation of c-Ret in the developing kidney is responsive to Pax2 gene dosage Hum. Mol. Genet., December 1, 2006; 15(23): 3420 - 3428. [Abstract] [Full Text] [PDF]

				S. Jain, J. P. Golden, D. Wozniak, E. Pehek, E. M. Johnson Jr, and J. Milbrandt RET Is Dispensable for Maintenance of Midbrain Dopaminergic Neurons in Adult Mice J. Neurosci., October 25, 2006; 26(43): 11230 - 11238. [Abstract] [Full Text] [PDF]

				C. C. Tsui, S. J. Shankland, and B. A. Pierchala Glial Cell Line-Derived Neurotrophic Factor and Its Receptor Ret Is a Novel Ligand-Receptor Complex Critical for Survival Response during Podocyte Injury J. Am. Soc. Nephrol., June 1, 2006; 17(6): 1543 - 1552. [Abstract] [Full Text] [PDF]

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				S. Jain, M. Encinas, E. M. Johnson Jr., and J. Milbrandt Critical and distinct roles for key RET tyrosine docking sites in renal development Genes & Dev., February 1, 2006; 20(3): 321 - 333. [Abstract] [Full Text] [PDF]

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				A. Wong, S. Bogni, P. Kotka, E. de Graaff, V. D'Agati, F. Costantini, and V. Pachnis Phosphotyrosine 1062 Is Critical for the In Vivo Activity of the Ret9 Receptor Tyrosine Kinase Isoform Mol. Cell. Biol., November 1, 2005; 25(21): 9661 - 9673. [Abstract] [Full Text] [PDF]

				G. Challen, B. Gardiner, G. Caruana, X. Kostoulias, G. Martinez, M. Crowe, D. F. Taylor, J. Bertram, M. Little, and S. M. Grimmond Temporal and spatial transcriptional programs in murine kidney development Physiol Genomics, October 17, 2005; 23(2): 159 - 171. [Abstract] [Full Text] [PDF]

				R. P. Scott, S. Eketjall, H. Aineskog, and C. F. Ibanez Distinct Turnover of Alternatively Spliced Isoforms of the RET Kinase Receptor Mediated by Differential Recruitment of the Cbl Ubiquitin Ligase J. Biol. Chem., April 8, 2005; 280(14): 13442 - 13449. [Abstract] [Full Text] [PDF]

				R. V. Sampogna and S. K. Nigam Implications of Gene Networks for Understanding Resilience and Vulnerability in the Kidney Branching Program Physiology, December 1, 2004; 19(6): 339 - 347. [Abstract] [Full Text] [PDF]

				O. H. Yu, I. J. Murawski, D. B. Myburgh, and I. R. Gupta Overexpression of RET leads to vesicoureteric reflux in mice Am J Physiol Renal Physiol, December 1, 2004; 287(6): F1123 - F1130. [Abstract] [Full Text] [PDF]

				S. Jain, C. K. Naughton, M. Yang, A. Strickland, K. Vij, M. Encinas, J. Golden, A. Gupta, R. Heuckeroth, E. M. Johnson Jr, et al. Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis Development, November 1, 2004; 131(21): 5503 - 5513. [Abstract] [Full Text] [PDF]

				M. Jijiwa, T. Fukuda, K. Kawai, A. Nakamura, K. Kurokawa, Y. Murakumo, M. Ichihara, and M. Takahashi A Targeting Mutation of Tyrosine 1062 in Ret Causes a Marked Decrease of Enteric Neurons and Renal Hypoplasia Mol. Cell. Biol., September 15, 2004; 24(18): 8026 - 8036. [Abstract] [Full Text] [PDF]

				M. M. Shah, R. V. Sampogna, H. Sakurai, K. T. Bush, and S. K. Nigam Branching morphogenesis and kidney disease Development, April 1, 2004; 131(7): 1449 - 1462. [Abstract] [Full Text] [PDF]

				A. Majumdar, S. Vainio, A. Kispert, J. McMahon, and A. P. McMahon Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development Development, July 15, 2003; 130(14): 3175 - 3185. [Abstract] [Full Text] [PDF]

				S. Gianino, J. R. Grider, J. Cresswell, H. Enomoto, and R. O. Heuckeroth GDNF availability determines enteric neuron number by controlling precursor proliferation Development, May 15, 2003; 130(10): 2187 - 2198. [Abstract] [Full Text] [PDF]

				D. Lang and J. A. Epstein Sox10 and Pax3 physically interact to mediate activation of a conserved c-RET enhancer Hum. Mol. Genet., April 15, 2003; 12(8): 937 - 945. [Abstract] [Full Text] [PDF]

				A. Popsueva, D. Poteryaev, E. Arighi, X. Meng, A. Angers-Loustau, D. Kaplan, M. Saarma, and H. Sariola GDNF promotes tubulogenesis of GFR{alpha}1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase J. Cell Biol., April 14, 2003; 161(1): 119 - 129. [Abstract] [Full Text] [PDF]

				A. S. McCallion, E. Stames, R. A. Conlon, and A. Chakravarti Phenotype variation in two-locus mouse models of Hirschsprung disease: Tissue-specific interaction between Ret and Ednrb PNAS, February 18, 2003; 100(4): 1826 - 1831. [Abstract] [Full Text] [PDF]

				K. Schumacher, R. Strehl, U. de Vries, H. J. Groene, and W. W. Minuth SBA-Positive Fibers between the CD Ampulla, Mesenchyme, and Renal Capsule J. Am. Soc. Nephrol., October 1, 2002; 13(10): 2446 - 2453. [Abstract] [Full Text] [PDF]

				D. M. Wellik, P. J. Hawkes, and M. R. Capecchi Hox11 paralogous genes are essential for metanephric kidney induction Genes & Dev., June 1, 2002; 16(11): 1423 - 1432. [Abstract] [Full Text] [PDF]

				M. Shirane, H. Sawa, Y. Kobayashi, T. Nakano, K. Kitajima, Y. Shinkai, K. Nagashima, and I. Negishi Deficiency of phospholipase C-{gamma}1 impairs renal development and hematopoiesis Development, March 14, 2002; 128(24): 5173 - 5180. [Abstract] [Full Text] [PDF]

				R. Nishinakamura, Y. Matsumoto, K. Nakao, K. Nakamura, A. Sato, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, S. Scully, D. L. Lacey, et al. Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development Development, March 10, 2002; 128(16): 3105 - 3115. [Abstract] [Full Text] [PDF]

				M. Willem, N. Miosge, W. Halfter, N. Smyth, I. Jannetti, E. Burghart, R. Timpl, and U. Mayer Specific ablation of the nidogen-binding site in the laminin {gamma}1 chain interferes with kidney and lung development Development, January 6, 2002; 129(11): 2711 - 2722. [Abstract] [Full Text] [PDF]

				E. de Graaff, S. Srinivas, C. Kilkenny, V. D'Agati, B. S. Mankoo, F. Costantini, and V. Pachnis Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis Genes & Dev., September 15, 2001; 15(18): 2433 - 2444. [Abstract] [Full Text] [PDF]

				H. Sakurai, K. T. Bush, and S. K. Nigam Identification of pleiotrophin as a mesenchymal factor involved in ureteric bud branching morphogenesis Development, January 9, 2001; 128(17): 3283 - 3293. [Abstract] [Full Text] [PDF]

				T Kume, K Deng, and B. Hogan Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract Development, January 4, 2000; 127(7): 1387 - 1395. [Abstract] [PDF]