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S. M. Vercauteren and H. J. Sutherland Constitutively active Notch4 promotes early human hematopoietic progenitor cell maintenance while inhibiting differentiation and causes lymphoid abnormalities in vivo Blood, October 15, 2004; 104(8): 2315 - 2322. [Abstract] [Full Text] [PDF] |
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F. MacKenzie, P. Duriez, B. Larrivee, L. Chang, I. Pollet, F. Wong, C. Yip, and A. Karsan Notch4-induced inhibition of endothelial sprouting requires the ankyrin repeats and involves signaling through RBP-J{kappa} Blood, September 15, 2004; 104(6): 1760 - 1768. [Abstract] [Full Text] [PDF] |
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I. Das, C. Craig, Y. Funahashi, K.-M. Jung, T.-W. Kim, R. Byers, A. P. Weng, J. L. Kutok, J. C. Aster, and J. Kitajewski Notch Oncoproteins Depend on {gamma}-Secretase/Presenilin Activity for Processing and Function J. Biol. Chem., July 16, 2004; 279(29): 30771 - 30780. [Abstract] [Full Text] [PDF] |
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Y. Liang and D. Ganem RBP-J (CSL) Is Essential for Activation of the K14/vGPCR Promoter of Kaposi's Sarcoma-Associated Herpesvirus by the Lytic Switch Protein RTA J. Virol., July 1, 2004; 78(13): 6818 - 6826. [Abstract] [Full Text] [PDF] |
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J. Dixelius, L. Jakobsson, E. Genersch, S. Bohman, P. Ekblom, and L. Claesson-Welsh Laminin-1 Promotes Angiogenesis in Synergy with Fibroblast Growth Factor by Distinct Regulation of the Gene and Protein Expression Profile in Endothelial Cells J. Biol. Chem., May 28, 2004; 279(22): 23766 - 23772. [Abstract] [Full Text] [PDF] |
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J. Chu and E. H. Bresnick Evidence That C Promoter-binding Factor 1 Binding Is Required for Notch-1-mediated Repression of Activator Protein-1 J. Biol. Chem., March 26, 2004; 279(13): 12337 - 12345. [Abstract] [Full Text] [PDF] |
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K. Horiuchi, G. Weskamp, L. Lum, H.-P. Hammes, H. Cai, T. A. Brodie, T. Ludwig, R. Chiusaroli, R. Baron, K. T. Preissner, et al. Potential Role for ADAM15 in Pathological Neovascularization in Mice Mol. Cell. Biol., August 15, 2003; 23(16): 5614 - 5624. [Abstract] [Full Text] [PDF] |
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D. Small, D. Kovalenko, R. Soldi, A. Mandinova, V. Kolev, R. Trifonova, C. Bagala, D. Kacer, C. Battelli, L. Liaw, et al. Notch Activation Suppresses Fibroblast Growth Factor-dependent Cellular Transformation J. Biol. Chem., April 25, 2003; 278(18): 16405 - 16413. [Abstract] [Full Text] [PDF] |
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T. Iso, Y. Hamamori, and L. Kedes Notch Signaling in Vascular Development Arterioscler Thromb Vasc Biol, April 1, 2003; 23(4): 543 - 553. [Abstract] [Full Text] [PDF] |
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T. Yamada, H. Yamazaki, T. Yamane, M. Yoshino, H. Okuyama, M. Tsuneto, T. Kurino, S.-I. Hayashi, and S. Sakano Regulation of osteoclast development by Notch signaling directed to osteoclast precursors and through stromal cells Blood, March 15, 2003; 101(6): 2227 - 2234. [Abstract] [Full Text] [PDF] |
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Z.-J. Liu, T. Shirakawa, Y. Li, A. Soma, M. Oka, G. P. Dotto, R. M. Fairman, O. C. Velazquez, and M. Herlyn Regulation of Notch1 and Dll4 by Vascular Endothelial Growth Factor in Arterial Endothelial Cells: Implications for Modulating Arteriogenesis and Angiogenesis Mol. Cell. Biol., January 1, 2003; 23(1): 14 - 25. [Abstract] [Full Text] |
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C. Talora, D. C. Sgroi, C. P. Crum, and G. P. Dotto Specific down-modulation of Notch1 signaling in cervical cancer cells is required for sustained HPV-E6/E7 expression and late steps of malignant transformation Genes & Dev., September 1, 2002; 16(17): 2252 - 2263. [Abstract] [Full Text] [PDF] |
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W. Wang, A. H. Campos, C. Z. Prince, Y. Mou, and M. J. Pollman Coordinate Notch3-Hairy-related Transcription Factor Pathway Regulation in Response to Arterial Injury. MEDIATOR ROLE OF PLATELET-DERIVED GROWTH FACTOR AND ERK J. Biol. Chem., June 21, 2002; 277(26): 23165 - 23171. [Abstract] [Full Text] [PDF] |
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V. Sriuranpong, M. W. Borges, C. L. Strock, E. K. Nakakura, D. N. Watkins, C. M. Blaumueller, B. D. Nelkin, and D. W. Ball Notch Signaling Induces Rapid Degradation of Achaete-Scute Homolog 1 Mol. Cell. Biol., May 1, 2002; 22(9): 3129 - 3139. [Abstract] [Full Text] [PDF] |
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K. G. Leong, X. Hu, L. Li, M. Noseda, B. Larrivee, C. Hull, L. Hood, F. Wong, and A. Karsan Activated Notch4 Inhibits Angiogenesis: Role of {beta}1-Integrin Activation Mol. Cell. Biol., April 15, 2002; 22(8): 2830 - 2841. [Abstract] [Full Text] [PDF] |
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S. Stier, T. Cheng, D. Dombkowski, N. Carlesso, and D. T. Scadden Notch1 activation increases hematopoietic stem cell self-renewal in vivo and favors lymphoid over myeloid lineage outcome Blood, April 1, 2002; 99(7): 2369 - 2378. [Abstract] [Full Text] [PDF] |
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S. J. Morrison, D. Qian, L. Jerabek, B. A. Thiel, I.-K. Park, P. S. Ford, M. J. Kiel, N. J. Schork, I. L. Weissman, and M. F. Clarke A Genetic Determinant That Specifically Regulates the Frequency of Hematopoietic Stem Cells J. Immunol., January 15, 2002; 168(2): 635 - 642. [Abstract] [Full Text] [PDF] |
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A. Stollewerk Recruitment of cell groups through Delta/Notch signalling during spider neurogenesis Development, January 12, 2002; 129(23): 5339 - 5348. [Abstract] [Full Text] [PDF] |
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S. L. Dunwoodie, M. Clements, D. B. Sparrow, X. Sa, R. A. Conlon, and R. S. P. Beddington Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm Development, January 4, 2002; 129(7): 1795 - 1806. [Abstract] [Full Text] [PDF] |
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B.M. WEINSTEIN and N.D. LAWSON Arteries, Veins, Notch, and VEGF Cold Spring Harb Symp Quant Biol, January 1, 2002; 67(0): 155 - 162. [Abstract] [PDF] |
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X.-Q. Yan, U. Sarmiento, Y. Sun, G. Huang, J. Guo, T. Juan, G. Van, M.-Y. Qi, S. Scully, G. Senaldi, et al. A novel Notch ligand, Dll4, induces T-cell leukemia/lymphoma when overexpressed in mice by retroviral-mediated gene transfer Blood, December 15, 2001; 98(13): 3793 - 3799. [Abstract] [Full Text] [PDF] |
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K. Kumano, S. Chiba, K. Shimizu, T. Yamagata, N. Hosoya, T. Saito, T. Takahashi, Y. Hamada, and H. Hirai Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression Blood, December 1, 2001; 98(12): 3283 - 3289. [Abstract] [Full Text] [PDF] |
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G. Wu, S. Lyapina, I. Das, J. Li, M. Gurney, A. Pauley, I. Chui, R. J. Deshaies, and J. Kitajewski SEL-10 Is an Inhibitor of Notch Signaling That Targets Notch for Ubiquitin-Mediated Protein Degradation Mol. Cell. Biol., November 1, 2001; 21(21): 7403 - 7415. [Abstract] [Full Text] [PDF] |
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M. T. Saxena, E. H. Schroeter, J. S. Mumm, and R. Kopan Murine Notch Homologs (N1-4) Undergo Presenilin-dependent Proteolysis J. Biol. Chem., October 19, 2001; 276(43): 40268 - 40273. [Abstract] [Full Text] [PDF] |
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N. D. Lawson, N. Scheer, V. N. Pham, C.-H. Kim, A. B. Chitnis, J. A. Campos-Ortega, and B. M. Weinstein Notch signaling is required for arterial-venous differentiation during embryonic vascular development Development, October 1, 2001; 128(19): 3675 - 3683. [Abstract] [Full Text] [PDF] |
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V. Lindner, C. Booth, I. Prudovsky, D. Small, T. Maciag, and L. Liaw Members of the Jagged/Notch Gene Families Are Expressed in Injured Arteries and Regulate Cell Phenotype via Alterations in Cell Matrix and Cell-Cell Interaction Am. J. Pathol., September 1, 2001; 159(3): 875 - 883. [Abstract] [Full Text] [PDF] |
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K. Ohishi, B. Varnum-Finney, R. E. Serda, C. Anasetti, and I. D. Bernstein The Notch ligand, Delta-1, inhibits the differentiation of monocytes into macrophages but permits their differentiation into dendritic cells Blood, September 1, 2001; 98(5): 1402 - 1407. [Abstract] [Full Text] [PDF] |
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T. Mizutani, Y. Taniguchi, T. Aoki, N. Hashimoto, and T. Honjo Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members PNAS, July 13, 2001; (2001) 161269998. [Abstract] [Full Text] [PDF] |
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T. Gridley Notch signaling during vascular development PNAS, May 8, 2001; 98(10): 5377 - 5378. [Full Text] [PDF] |
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H. Uyttendaele, J. Ho, J. Rossant, and J. Kitajewski Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium PNAS, May 8, 2001; 98(10): 5643 - 5648. [Abstract] [Full Text] [PDF] |
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V. Sriuranpong, M. W. Borges, R. K. Ravi, D. R. Arnold, B. D. Nelkin, S. B. Baylin, and D. W. Ball Notch Signaling Induces Cell Cycle Arrest in Small Cell Lung Cancer Cells Cancer Res., April 1, 2001; 61(7): 3200 - 3205. [Abstract] [Full Text] |
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D. Rudel and J. Kimble Conservation of glp-1 Regulation and Function in Nematodes Genetics, February 1, 2001; 157(2): 639 - 654. [Abstract] [Full Text] |
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S. Kusano and N. Raab-Traub An Epstein-Barr Virus Protein Interacts with Notch J. Virol., January 1, 2001; 75(1): 384 - 395. [Abstract] [Full Text] |
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K. Shimizu, S. Chiba, N. Hosoya, K. Kumano, T. Saito, M. Kurokawa, Y. Kanda, Y. Hamada, and H. Hirai Binding of Delta1, Jagged1, and Jagged2 to Notch2 Rapidly Induces Cleavage, Nuclear Translocation, and Hyperphosphorylation of Notch2 Mol. Cell. Biol., September 15, 2000; 20(18): 6913 - 6922. [Abstract] [Full Text] |
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P. Carmeliet Fibroblast Growth Factor-1 Stimulates Branching and Survival of Myocardial Arteries : A Goal for Therapeutic Angiogenesis? Circ. Res., August 4, 2000; 87(3): 176 - 178. [Full Text] [PDF] |
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S. Tsai, J. Fero, and S. Bartelmez Mouse Jagged2 is differentially expressed in hematopoietic progenitors and endothelial cells and promotes the survival and proliferation of hematopoietic progenitors by direct cell-to-cell contact Blood, August 1, 2000; 96(3): 950 - 957. [Abstract] [Full Text] [PDF] |
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S. Jeffries and A. J. Capobianco Neoplastic Transformation by Notch Requires Nuclear Localization Mol. Cell. Biol., June 1, 2000; 20(11): 3928 - 3941. [Abstract] [Full Text] |
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J. R. Shutter, S. Scully, W. Fan, W. G. Richards, J. Kitajewski, G. A. Deblandre, C. R. Kintner, and K. L. Stark Dll4, a novel Notch ligand expressed in arterial endothelium Genes & Dev., June 1, 2000; 14(11): 1313 - 1318. [Abstract] [Full Text] |
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L. T. Krebs, Y. Xue, C. R. Norton, J. R. Shutter, M. Maguire, J. P. Sundberg, D. Gallahan, V. Closson, J. Kitajewski, R. Callahan, et al. Notch signaling is essential for vascular morphogenesis in mice Genes & Dev., June 1, 2000; 14(11): 1343 - 1352. [Abstract] [Full Text] |
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K. Ohishi, B. Varnum-Finney, D. Flowers, C. Anasetti, D. Myerson, and I. D. Bernstein Monocytes express high amounts of Notch and undergo cytokine specific apoptosis following interaction with the Notch ligand, Delta-1 Blood, May 1, 2000; 95(9): 2847 - 2854. [Abstract] [Full Text] [PDF] |
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F. Radtke, I. Ferrero, A. Wilson, R. Lees, M. Aguet, and H. R. MacDonald Notch1 Deficiency Dissociates the Intrathymic Development of Dendritic Cells and T Cells J. Exp. Med., April 3, 2000; 191(7): 1085 - 1094. [Abstract] [Full Text] [PDF] |
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W. Han, Q. Ye, and M. A. S. Moore A soluble form of human Delta-like-1 inhibits differentiation of hematopoietic progenitor cells Blood, March 1, 2000; 95(5): 1616 - 1625. [Abstract] [Full Text] [PDF] |
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M. Rones, K. McLaughlin, M Raffin, and M Mercola Serrate and Notch specify cell fates in the heart field by suppressing cardiomyogenesis Development, January 9, 2000; 127(17): 3865 - 3876. [Abstract] [PDF] |
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T Ito, N Udaka, T Yazawa, K Okudela, H Hayashi, T Sudo, F Guillemot, R Kageyama, and H Kitamura Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium Development, January 9, 2000; 127(18): 3913 - 3921. [Abstract] [PDF] |
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A Zine, T. Van De Water, and F de Ribaupierre Notch signaling regulates the pattern of auditory hair cell differentiation in mammals Development, January 8, 2000; 127(15): 3373 - 3383. [Abstract] [PDF] |
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T. Veikkola, M. Karkkainen, L. Claesson-Welsh, and K. Alitalo Regulation of Angiogenesis via Vascular Endothelial Growth Factor Receptors Cancer Res., January 1, 2000; 60(2): 203 - 212. [Full Text] |
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K. Shimizu, S. Chiba, K. Kumano, N. Hosoya, T. Takahashi, Y. Kanda, Y. Hamada, Y. Yazaki, and H. Hirai Mouse Jagged1 Physically Interacts with Notch2 and Other Notch Receptors. ASSESSMENT BY QUANTITATIVE METHODS J. Biol. Chem., November 12, 1999; 274(46): 32961 - 32969. [Abstract] [Full Text] [PDF] |
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E. Tsifrina, N. M. Ananyeva, G. Hastings, and G. Liau Identification and Characterization of Three cDNAs That Encode Putative Novel Hyaluronan-Binding Proteins, Including an Endothelial Cell-Specific Hyaluronan Receptor Am. J. Pathol., November 1, 1999; 155(5): 1625 - 1633. [Abstract] [Full Text] [PDF] |
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M. P. Felli, M. Maroder, T. A. Mitsiadis, A. F. Campese, D. Bellavia, A. Vacca, R. S. Mann, L. Frati, U. Lendahl, A. Gulino, et al. Expression pattern of Notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand–receptor interactions in intrathymic T cell development Int. Immunol., July 1, 1999; 11(7): 1017 - 1025. [Abstract] [Full Text] [PDF] |
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K. Penta, J. A. Varner, L. Liaw, C. Hidai, R. Schatzman, and T. Quertermous Del1 Induces Integrin Signaling and Angiogenesis by Ligation of alpha Vbeta 3 J. Biol. Chem., April 16, 1999; 274(16): 11101 - 11109. [Abstract] [Full Text] [PDF] |
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N. Carlesso, J. C. Aster, J. Sklar, and D. T. Scadden Notch1-Induced Delay of Human Hematopoietic Progenitor Cell Differentiation Is Associated With Altered Cell Cycle Kinetics Blood, February 1, 1999; 93(3): 838 - 848. [Abstract] [Full Text] [PDF] |
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S. Du Yan, Y. Shi, A. Zhu, J. Fu, H. Zhu, Y. Zhu, L. Gibson, E. Stern, K. Collison, F. Al-Mohanna, et al. Role of ERAB/L-3-Hydroxyacyl-coenzyme A Dehydrogenase Type II Activity in Abeta -induced Cytotoxicity J. Biol. Chem., January 22, 1999; 274(4): 2145 - 2156. [Abstract] [Full Text] [PDF] |
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T Ikeya and S Hayashi Interplay of Notch and FGF signaling restricts cell fate and MAPK activation in the Drosophila trachea Development, January 10, 1999; 126(20): 4455 - 4463. [Abstract] [PDF] |
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Y Hamada, Y Kadokawa, M Okabe, M Ikawa, J. Coleman, and Y Tsujimoto Mutation in ankyrin repeats of the mouse Notch2 gene induces early embryonic lethality Development, January 8, 1999; 126(15): 3415 - 3424. [Abstract] [PDF] |
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H. K. Kim and G. Siu The Notch Pathway Intermediate HES-1 Silences CD4 Gene Expression Mol. Cell. Biol., December 1, 1998; 18(12): 7166 - 7175. [Abstract] [Full Text] |
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S. Jarriault, O. Le Bail, E. Hirsinger, O. Pourquié, F. Logeat, C. F. Strong, C. Brou, N. G. Seidah, and A. Israël Delta-1 Activation of Notch-1 Signaling Results in HES-1 Transactivation Mol. Cell. Biol., December 1, 1998; 18(12): 7423 - 7431. [Abstract] [Full Text] |
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P. Jones, G. May, L. Healy, J. Brown, G. Hoyne, S. Delassus, and T. Enver Stromal Expression of Jagged 1 Promotes Colony Formation by Fetal Hematopoietic Progenitor Cells Blood, September 1, 1998; 92(5): 1505 - 1511. [Abstract] [Full Text] [PDF] |
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B. Herren, B. Levkau, E. W. Raines, and R. Ross Cleavage of beta -Catenin and Plakoglobin and Shedding of VE-Cadherin during Endothelial Apoptosis: Evidence for a Role for Caspases and Metalloproteinases Mol. Biol. Cell, June 1, 1998; 9(6): 1589 - 1601. [Abstract] [Full Text] |
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B. Varnum-Finney, L. E. Purton, M. Yu, C. Brashem-Stein, D. Flowers, S. Staats, K. A. Moore, I. Le Roux, R. Mann, G. Gray, et al. The Notch Ligand, Jagged-1, Influences the Development of Primitive Hematopoietic Precursor Cells Blood, June 1, 1998; 91(11): 4084 - 4091. [Abstract] [Full Text] [PDF] |
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A. Bigas, D. I. K. Martin, and L. A. Milner Notch1 and Notch2 Inhibit Myeloid Differentiation in Response to Different Cytokines Mol. Cell. Biol., April 1, 1998; 18(4): 2324 - 2333. [Abstract] [Full Text] |
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E. J. A. Hubbard, G. Wu, J. Kitajewski, and I. Greenwald sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins Genes & Dev., December 1, 1997; 11(23): 3182 - 3193. [Abstract] [Full Text] [PDF] |
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D. Sherwood and D. McClay Identification and localization of a sea urchin Notch homologue: insights into vegetal plate regionalization and Notch receptor regulation Development, January 9, 1997; 124(17): 3363 - 3374. [Abstract] [PDF] |
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S. Dunwoodie, D Henrique, S. Harrison, and R. Beddington Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryo Development, January 8, 1997; 124(16): 3065 - 3076. [Abstract] [PDF] |
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J. de la Pompa, A Wakeham, K. Correia, E Samper, S Brown, R. Aguilera, T Nakano, T Honjo, T. Mak, J Rossant, et al. Conservation of the Notch signalling pathway in mammalian neurogenesis Development, January 3, 1997; 124(6): 1139 - 1148. [Abstract] [PDF] |
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