The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Ros, M. A.
	Articles by Fallon, J. F.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Ros, M. A.
	Articles by Fallon, J. F.

Carrington, J. L. and Fallon, J. F (1984). The stages of flank ectoderm capable of responding to ridge induction in the chick embryo. J. Embryol. Exp. Morphol 84, 19-34.[Medline]

Carrington, J. L. and Fallon, J. F (1984). Evidence that the ectoderm is the affected layer in the wingless mutant chick embryo. J. Exp. Zool 232, 297-308.[Medline]

Carrington, J. L. and Fallon, J. F (1986). Experimental manipulation leading to induction of dorsal ectodermal ridges on normal limb buds results in a phenocopy of the Eudiplopodia chick mutant. Dev. Biol 116, 130-137.[Medline]

Carrington, J. L. and Fallon, J. F (1988). Initial limb budding is independent of apical ectodermal ridge activity: evidence from a limbless mutant. Development 104, 361-367.[Abstract/Free Full Text]

Chang, D. T., Lopez, A., Von Kessler, D. P., Chang, C., Simandl, B. K., Zhao, R., Selding, M. F., Fallon, J. F. and Beachy, P. A (1994). Products, genetic linkage and limb patterning activity of a murine hedgehog gene. Development 120, 3339-3353.[Abstract]

Coates, M. I (1993). Ancestors and homology (the origin of the tetrapod limb). Acta Biotheoretica 41, 411-424.[Medline]

Coelho, C. N. D., Krabbenhoft, K. M., Upholt, W. B., Fallon, J. F. and Kosher, R. A (1991). Altered expression of the chicken homeo-box containing genes GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos. Development 113, 1487-1493.[Abstract]

Cohn, M. J., Izpis\234a-Belmonte, J. C., Abud, H., Heath, J. K. and Tickle, C (1995). Fibroblast growth factors induce additional limb development from the flank of chick embryos. Cell 80, 739-746.[Medline]

Crossley, H. P. and Martin, G. R (1995). The mouse Fgf-8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.[Abstract]

Crossley, H. P., Minowada, G., MacArthur, C. A. and Martin, G. R (1996). Roles for FGF8 in the induction, initiation and maintenance of chick limb development. Cell 84, 127-136.[Medline]

Davis, C. A., Holmyard, D. P., Millen, K. J. and Joyner, A. L (1991). Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum. Development 111, 287-298.[Abstract]

Dealy, C. N., Roth, A., Ferrari, D., Brown, A. M. C. and Kosher, R. A (1993). Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes. Mech. Dev 43, 175-186.[Medline]

Dealy, C. N. and Kosher, R. A (1995). Studies on insulin-like growth factor-I and insulin in chick limb morphogenesis. Dev. Dyn 202, 67-79.[Medline]

Dealy, C. N. and Kosher, R. A (1996). IGF-1, insulin and FGFs induce outgrowth of the limb buds of amelic mutant chick embryos. Development 122, 1323-1330.[Abstract]

Dono, R. and Zeller, R (1994). Cell type-specific nuclear translocation of fibroblast growth factor-2 isoforms during chicken kidney and limb morphogenesis. Dev. Biol 163, 316-330.[Medline]

Fallon, J. F., Lopez, A., Ros, M. A., Savage, M., Olwin, B. and Simandl, B. K (1994). FGF2: apical ectodermal ridge growth signal for the chick limb development. Science 264, 104-107.[Abstract/Free Full Text]

Francis, P. H., Richardson, M. K., Brickell, P. M. and Tickle, C (1994). Bone morphogenetic proteins and a signaling pathway that controls patterning in the developing chick limb. Development 120, 209-218.[Abstract]

Francis-West, P. H., Robertson, K., Ede, D. A., Rodriguez, C., Izpisua-Belmonte, J. C., Houston, B., Burt, D. W., Gribbin, C., Brickell, P. M. and Tickle, C (1995). Expression of genes encoding bone morphogenetic proteins and sonic hedgehog in talpid (ta3) limb buds: their relationships in the signalling cascade involved in limb patterning. Dev. Dyn 203, 187-197.[Medline]

Gardner, C. A. and Barald, K. F (1992). Expression patterns of Engrailed-like proteins in the chick embryo. Dev. Dyn 193, 370-388.[Medline]

Geduspan, J. S. and MacCabe, J. A (1987). The ectodermal control of mesodermal patterns of differentiation in the developing chick wing. Dev. Biol 124, 398-408.[Medline]

Geduspan, J. S. and MacCabe, J. A (1989). Transfer of dorsoventral information from mesoderm to ectoderm at the onset of limb development. Anat. Rec 224, 79-87.[Medline]

Geduspan, J. S. and Solursh, M (1992). A growth-promoting influence from the mesonephros during limb outgrowth. Dev. Biol 151, 242-250.[Medline]

Geduspan, J. S. and Solursh, M (1993). Effects on the mesonephros and Insulin-like growth factor I on chondrogenesis of limb explants. Dev. Biol 156, 500-508.[Medline]

Hamburger, V (1938). Morphogenetic and axial self-differentiation of transplanted limb primordia of 2-day chick embryos. J. Exp. Zool 77, 379-399.

Hamburger, V. and Hamilton, H (1951). A series of normal stages in the development of the chick embryos. J. Morphol 88, 49-92.

Hardy, A., Richardson, M. K., Francis-West, P. H., Rodriguez, C., Izpis\234a-Belmonte, J. C., Duprez, D. and Wolpert, L (1995). Gene expression, polarizing activity and skeletal patterning in reaggregated hind limb mesenchyme. Development 121, 4329-4337.[Abstract]

Harrison, R. G (1918). Experiments on the development of the fore limb of amblystoma, a self-differentiating equipotential system. J. Exp. Zool 25, 13-461.

Harrison, R. G (1921). On relations of symmetry in transplanted limbs. J. Exp. Zool 32, 1-136.

Heikinheimo, M., Lawshe, A., Shackleford, G. M., Wilson, D. B. and MacArthur, C. A (1994). Fgf-8 expression in the post-gastrulation mouse suggest roles in the development of the face, limbs and central nervous system. Mech. Dev 48, 129-138.[Medline]

Hornbruch, A. and Wolpert, L (1991). The spatial and temporal distribution of polarizing activity in the flank of the pre-limb-bud stages in the chick embryo,. Development 111, 725-31.[Abstract]

Izpis\234a-Belmonte, J. C., Tickle, C., Dolle, P., Wolpert, L. and Duboule, D (1991). Expression of the homeobox Hox-4 genes and the specification of position in chick wing development. Nature 350, 585-589.[Medline]

Izpis\234a-Belmonte, J. C., Brown, J. C., Duboule, D. and Tickle, C (1992). Expression of Hox-4 genes in the chick wing links pattern formation to the epithelial-mesenchymal interactions that mediate growth. EMBO J 11, 1451-1457.[Medline]

Kieny, M (1960). Role inducteur du mesoderme dans la differentiation precoce du bourgeon de membre chez l'embryon de Poulet. J. Embryol. Exp. Morphol 8, 457-467.

Krabbenhoft, K. M. and Fallon, J. F (1989). The formation of leg or wing specific structures by leg bud cells grafted to the wing bud is influenced by proximity to the apical ridge. Dev. Biol 131, 373-382.[Medline]

Lanser, M. E. and Fallon, J. F (1984). Development of the lateral motor column in the limbless mutant chick embryo. J. Neurosci 4, 2043-2050.[Abstract]

Laufer, E., Nelson, C., Johson, R. L. Morgan, B. A. and Tabin, C (1994). Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.[Medline]

Lewis, J. H. and Wolpert, L (1976). The principle of non-equivalence in development. J. Theor. Biol 62, 479-90.[Medline]

Lopez-Mart\222nez, A., Chang, D. T., Chiang, C., Porter, J. A., Ros, M. A., Simandl, B. K., Beachy, P. A. and Fallon, J. F (1995). Limb-patterning activity and restricted posterior localization of the amino terminal product of Sonic hedgehog cleavage. Curr. Biol 5, 791-796.[Medline]

Mahmood, R., Bresnick, J., Hornbruch, A., Mahony, C., Morton, N., Colquhoun, K., Martin. P., Lumsden, A., Dickson, C. and Mason, I (1995). A role for FGF8 in the initiation and maintenance of vertebrate limb bud outgrowth. Curr. Biol 5, 797-806.[Medline]

Martin, G. R (1995). Why thumbs are up. Nature 374, 410-411.[Medline]

MacCabe, J. A., Errick, J. and Saunders, J. W (1974). Ectodermal control of the dorsoventral axis in the leg bud of the chick embryo. Dev. Biol 39, 69-82.[Medline]

Meinhardt, H (1983). A boundary model for pattern formation in vertebrate limbs. J. Embryol. Exp. Morphol 76, 115-137.[Medline]

Mima, T., Ohuchi, H., Noji, S. and Mikawa, T (1995). FGF can induce outgrowth of somatic mesoderm both inside and outside of limb-forming regions. Dev. Biol 167, 617-620.[Medline]

Niswander, L. and Martin, G. R (1992). Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse. Development 114, 755-768.[Abstract]

Niswander, L., Tickle, C., Vogel, A., Booth, I. and Martin, G. R (1993). FGF4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb. Cell 75, 579-587.[Medline]

Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C (1994). Positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.[Medline]

Ohuchi, H., Yoshioka, H., Tanaka, H., Kawakami, Y., Nohno, T. and Noji, S (1994). Involvement of androgen-induced growth factor (FGF8) gene in mouse embryogenesis and morphogenesis. Biochem. Biophys. Res. Com 204, 882-888.[Medline]

Ohuchi, H., Nakagawa, T., Yamahuchi, M., Ohata, T., Yoshioka, H., Kuwana, T., Mima, T., Mikawa, T., Nohno, T. and Noji, S (1995). An additional limb can be induced from the flank of the chick embryo by FGF4. Biochem. Biophys. Res. Com 209, 809-816.[Medline]

Parr, B. A. and McMahon, A (1995). Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes in mouse limb. Nature 374, 350-353.[Medline]

Pinot, M (1970). Le role du mesoderme somitique dans la morphogenese precoce des membres de l'embryon de Poulet. J. Embryol. Exp. Morph 23, 109-151.[Medline]

Prahlad, R. B., Skala, G., Jones, D. B. and Briles, W. S (1979). Limbless : A new genetic mutant in the chick. J. Exp. Zool 209, 427-434.[Medline]

Riddle, R. D., Johnson, R. L., Laufer, E. and Tabin, C (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.[Medline]

Riddle, R. D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T. M. and Tabin, C (1995). Induction of the LIM homeobox gene Lmx1 by Wnt7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631-640.[Medline]

Robert, B., Lyons, G., Simandl, B. K., Kuroiwa, A. and Buckingham, M (1991). The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds. Genes and Dev 5, 2363-2374.[Abstract/Free Full Text]

Ros, M. A., Lyons, G. E., Mackem, S. and Fallon, J. F (1994). Recombinant limbs as a model to study homeobox gene regulation during limb development. Dev. Biol 166, 59-72.[Medline]

Rosenquist, G. C (1971). The origin and movement of the limb-bud epithelium and mesenchyme in the chick embryo as determined by radioautographic mapping. J. Embryol. Exp. Morphol 25, 85-96.[Medline]

Rowe, D. A. and Fallon, J. F (1982). The proximodistal determination of skeletal parts in the developing chick leg. J. Embryol. Exp. Morphol 68, 1-7.[Medline]

Rubin, L. and Saunders, J. W. Jr (1972). Ectodermal-mesodermal interactions in the growth of limb buds in the chick embryo: constancy and temporal limits of the ectodermal induction. Dev. Biol 28, 94-112.[Medline]

Saunders, J. W., Jr (1948). The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm. J. Exp. Zool 108, 363-403.[Medline]

Saunders, J. W., Jr. and Reuss, C (1974). Inductive and axial properties of prospective wing-bud mesoderm in the chick embryo. Dev. Biol 38, 41-50.[Medline]

Saunders, J. W. Jr., Gasseling, M. T. and Errick, J. E (1976). Inductive activity and enduring cellular constitution of a supernumerary apical ectodermal ridge grafted to the limb bud of the chick embryo. Dev. Biol 50, 16-25.[Medline]

Savage, M. P., Hart, C. E., Riley, B., Sasse, J., Olwin, B. B. and Fallon, J. F (1993). Distribution of FGF2 suggests it has a role in chick limb bud growth. Dev. Dyn 198, 159-170.[Medline]

Savage, M. P. and Fallon, J. F (1995). FGF2 mRNA and its antisense message are expressed in a developmentally specific manner in the chick limb bud and mesonephros. Dev. Dyn 202, 343-353.[Medline]

Searls, R. L. and Janners, M. Y (1971). The initiation of limb bud outgrowth in the embryonic chick. Dev. Biol 24, 198-213.[Medline]

Stephens, T. D. and McNulty, T. R (1981). Evidence for a metameric pattern in the development of the chick humerus. J. Embryol. Exp. Morphol 61, 191-205.[Medline]

Stephens, T. D., Spall, R., Baker, W. C., Hiatt, S. R., Pugmire, D. E., Shaker, M. R., Willis, H. J. and Winger, K. P (1991). Axial and paraxial influences on limb morphogenesis. J. Morphol 208, 367-379.

Stephens, T. D., Baker, W. C., Cotterell, J. W., Edwards, D. R., Pugmire, D. S., Roberts, S. G., Shaker, M. R., Willis, H. J. and Winger, K. P (1993). Evaluation of the chick wing territory as an equipotential self-differentiating system. Dev. Dyn 197, 157-68.[Medline]

Stocum, D. L. and Fallon, J. F (1982). Control of pattern formation in urodele limb ontogeny: a review and a hypothesis. J. Embryol. Exp. Morphol 69, 7-36.[Medline]

Streck, R. D., Wood, T. L., Hsu, M. S. and Pintar, J. E (1992). Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs. Dev. Biol 151, 586-96.[Medline]

Summerbell, D., Lewis, J. H. and Wolpert, L (1973). Positional information in chick limb morphogenesis. Nature 224, 492-496.

Summerbell, D (1974). A quantitative analysis of the effect of excision of the apical ridge from the chick limb bud. J. Embryol. Exp. Morphol 32, 651-660.[Medline]

Suzuki, H. R., Sakamoto, H., Yoshida, T., Sugimora, T., Terada, M. and Solursh, M (1992). Localization of Hst1 transcripts to the apical ectodermal ridge in the mouse embryo. Dev. Biol 150, 219-222.[Medline]

Tickle, C (1981). The number of polarizing region cells required to specify additional digits in the developing chick wing. Nature 289, 295-298.[Medline]

Tickle, C., Summerbell, D. and Wolpert, L (1975). Positional signaling and specification of digits in chick limb morphogenesis. Nature 254, 199-202.[Medline]

Todt, W. and Fallon, J. F (1984). Development of the apical ectodermal ridge in the chick wing bud. J. Embryol. Exp. Morph 80, 21-41.[Medline]

Vogel, A. and Tickle, C (1993). FGF4 maintains polarizing activity of posterior limb bud cells in vivo and in vitro. Development 119, 199-206.[Abstract]

Vogel, A., Rodriguez, C., Warnken, W. and Izpis\234a Belmonte, J. C (1995). Dorsal cell fate specified by chick Lmx1 during vertebrate limb development. Nature 378, 716-720.[Medline]

Vogel, A., Rodriguez, C. and Izpis\234a Belmonte, J. C (1996). Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development 122, 1737-1750.[Abstract]

Wilkinson, D. G. and Nieto, M. A (1993). Detection of messenger RNA by insitu hybridization to tissues sections and whole mounts. Methods Enzymol 225, 361-373.[Medline]

Yang, Y. and Niswander, L (1995). Interaction between the signaling molecules WNT7a and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell 80, 939-947.[Medline]

Zwilling, E (1955). Ectoderm-mesoderm relationship in the development of the chick embryo limb bud. J. Exp. Zool 128, 423-442.

This article has been cited by other articles:

P. Valasek, D. J. R. Evans, F. Maina, M. Grim, and K. Patel
A dual fate of the hindlimb muscle mass: cloacal/perineal musculature develops from leg muscle cells
Development, February 1, 2005; 132(3): 447 - 458.
[Abstract] [Full Text] [PDF]

M. A. Ros, R. D. Dahn, M. Fernandez-Teran, K. Rashka, N. C. Caruccio, S. M. Hasso, J. J. Bitgood, J. J. Lancman, and J. F. Fallon
The chick oligozeugodactyly (ozd) mutant lacks sonic hedgehog function in the limb
Development, February 1, 2003; 130(3): 527 - 537.
[Abstract] [Full Text] [PDF]

D. G. McFadden, J. McAnally, J. A. Richardson, J. Charite, and E. N. Olson
Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding
Development, January 7, 2002; 129(13): 3077 - 3088.
[Abstract] [Full Text] [PDF]

S. Pizette, C. Abate-Shen, and L. Niswander
BMP controls proximodistal outgrowth, via induction of the apical ectodermal ridge, and dorsoventral patterning in the vertebrate limb
Development, November 15, 2001; 128(22): 4463 - 4474.
[Abstract] [Full Text] [PDF]

R. A. Kimmel, D. H. Turnbull, V. Blanquet, W. Wurst, C. A. Loomis, and A. L. Joyner
Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation
Genes & Dev., June 1, 2000; 14(11): 1377 - 1389.
[Abstract] [Full Text]

M. Fernandez-Teran, M. E. Piedra, I. S. Kathiriya, D. Srivastava, J. C. Rodriguez-Rey, and M. A. Ros
Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway
Development, May 15, 2000; 127(10): 2133 - 2142.
[Abstract] [PDF]

H Grandel, B. Draper, and S Schulte-Merker
dackel acts in the ectoderm of the zebrafish pectoral fin bud to maintain AER signaling
Development, January 10, 2000; 127(19): 4169 - 4178.
[Abstract] [PDF]

J Charite, D. McFadden, and E. Olson
The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development
Development, January 6, 2000; 127(11): 2461 - 2470.
[Abstract] [PDF]

A. Moon, A. Boulet, and M. Capecchi
Normal limb development in conditional mutants of Fgf4
Development, January 3, 2000; 127(5): 989 - 996.
[Abstract] [PDF]

J. Galceran, I. Fariñas, M. J. Depew, H. Clevers, and R. Grosschedl
Wnt3a-/--like phenotype and limb deficiency in Lef1-/-Tcf1-/- mice
Genes & Dev., March 15, 1999; 13(6): 709 - 717.
[Abstract] [Full Text]

C. Neumann, H Grandel, W Gaffield, S Schulte-Merker, and C Nusslein-Volhard
Transient establishment of anteroposterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity
Development, January 11, 1999; 126(21): 4817 - 4826.
[Abstract] [PDF]

R. Widelitz, T. Jiang, C. Chen, N. Stott, and C. Chuong
Wnt-7a in feather morphogenesis: involvement of anterior-posterior asymmetry and proximal-distal elongation demonstrated with an in vitro reconstitution model
Development, January 6, 1999; 126(12): 2577 - 2587.
[Abstract] [PDF]

A Zuniga and R Zeller
Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity
Development, January 1, 1999; 126(1): 13 - 21.
[Abstract] [PDF]

I Munoz-Sanjuan, B. Simandl, J. Fallon, and J Nathans
Expression of chicken fibroblast growth factor homologous factor (FHF)-1 and of differentially spliced isoforms of FHF-2 during development and involvement of FHF-2 in chicken limb development
Development, January 1, 1999; 126(2): 409 - 421.
[Abstract] [PDF]

G. R. Martin
The roles of FGFs in the early development of vertebrate�limbs
Genes & Dev., June 1, 1998; 12(11): 1571 - 1586.
[Full Text]

M Takahashi, K Tamura, D Buscher, H Masuya, S Yonei-Tamura, K Matsumoto, M Naitoh-Matsuo, J Takeuchi, K Ogura, T Shiroishi, et al.
The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development
Development, January 11, 1998; 125(22): 4417 - 4425.
[Abstract] [PDF]

C Rodriguez-Esteban, J. Schwabe, J. Pena, D. Rincon-Limas, J Magallon, J Botas, and J. Belmonte
Lhx2, a vertebrate homologue of apterous, regulates vertebrate limb outgrowth
Development, January 10, 1998; 125(20): 3925 - 3934.
[Abstract] [PDF]

F Reifers, H Bohli, E. Walsh, P. Crossley, D. Stainier, and M Brand
Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis
Development, January 7, 1998; 125(13): 2381 - 2395.
[Abstract] [PDF]

C. Loomis, R. Kimmel, C. Tong, J Michaud, and A. Joyner
Analysis of the genetic pathway leading to formation of ectopic apical ectodermal ridges in mouse Engrailed-1 mutant limbs
Development, January 3, 1998; 125(6): 1137 - 1148.
[Abstract] [PDF]

X Xu, M Weinstein, C Li, M Naski, R. Cohen, D. Ornitz, P Leder, and C Deng
Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction
Development, January 2, 1998; 125(4): 753 - 765.
[Abstract] [PDF]

Y. Imokawa and K. Yoshizato
Expression of Sonic hedgehog gene in regenerating newt limb blastemas recapitulates that in developing limb�buds
PNAS, August 19, 1997; 94(17): 9159 - 9164.
[Abstract] [Full Text] [PDF]

T. Stratford, K Kostakopoulou, and M Maden
Hoxb-8 has a role in establishing early anterior-posterior polarity in chick forelimb but not hindlimb
Development, January 11, 1997; 124(21): 4225 - 4234.
[Abstract] [PDF]

V Knezevic, R De Santo, K Schughart, U Huffstadt, C Chiang, K. Mahon, and S Mackem
Hoxd-12 differentially affects preaxial and postaxial chondrogenic branches in the limb and regulates Sonic hedgehog in a positive feedback loop
Development, January 11, 1997; 124(22): 4523 - 4536.
[Abstract] [PDF]

M Altabef, J. Clarke, and C Tickle
Dorso-ventral ectodermal compartments and origin of apical ectodermal ridge in developing chick limb
Development, January 11, 1997; 124(22): 4547 - 4556.
[Abstract] [PDF]

H Ohuchi, T Nakagawa, A Yamamoto, A Araga, T Ohata, Y Ishimaru, H Yoshioka, T Kuwana, T Nohno, M Yamasaki, et al.
The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor
Development, January 6, 1997; 124(11): 2235 - 2244.
[Abstract] [PDF]

C Logan, A Hornbruch, I Campbell, and A Lumsden
The role of Engrailed in establishing the dorsoventral axis of the chick limb
Development, January 6, 1997; 124(12): 2317 - 2324.
[Abstract] [PDF]

M. Ros, M Sefton, and M. Nieto
Slug, a zinc finger gene previously implicated in the early patterning of the mesoderm and the neural crest, is also involved in chick limb development
Development, January 5, 1997; 124(9): 1821 - 1829.
[Abstract] [PDF]

J. Michaud, F Lapointe, and N. Le Douarin
The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure
Development, January 4, 1997; 124(8): 1453 - 1463.
[Abstract] [PDF]

M. Lewandoski, E.N. Meyers, and G.R. Martin
Analysis of Fgf8 Gene Function in Vertebrate Development
Cold Spring Harb Symp Quant Biol, January 1, 1997; 62(0): 159 - 168.
[Abstract] [PDF]

U Grieshammer, G Minowada, J. Pisenti, U. Abbott, and G. Martin
The chick limbless mutation causes abnormalities in limb bud dorsal-ventral patterning: implications for the mechanism of apical ridge formation
Development, January 12, 1996; 122(12): 3851 - 3861.
[Abstract] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Ros, M. A.

Articles by Fallon, J. F.

Search for Related Content

PubMed

PubMed Citation

Articles by Ros, M. A.

Articles by Fallon, J. F.

				M. A. Ros, R. D. Dahn, M. Fernandez-Teran, K. Rashka, N. C. Caruccio, S. M. Hasso, J. J. Bitgood, J. J. Lancman, and J. F. Fallon The chick oligozeugodactyly (ozd) mutant lacks sonic hedgehog function in the limb Development, February 1, 2003; 130(3): 527 - 537. [Abstract] [Full Text] [PDF]

				D. G. McFadden, J. McAnally, J. A. Richardson, J. Charite, and E. N. Olson Misexpression of dHAND induces ectopic digits in the developing limb bud in the absence of direct DNA binding Development, January 7, 2002; 129(13): 3077 - 3088. [Abstract] [Full Text] [PDF]

				S. Pizette, C. Abate-Shen, and L. Niswander BMP controls proximodistal outgrowth, via induction of the apical ectodermal ridge, and dorsoventral patterning in the vertebrate limb Development, November 15, 2001; 128(22): 4463 - 4474. [Abstract] [Full Text] [PDF]

				R. A. Kimmel, D. H. Turnbull, V. Blanquet, W. Wurst, C. A. Loomis, and A. L. Joyner Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation Genes & Dev., June 1, 2000; 14(11): 1377 - 1389. [Abstract] [Full Text]

				M. Fernandez-Teran, M. E. Piedra, I. S. Kathiriya, D. Srivastava, J. C. Rodriguez-Rey, and M. A. Ros Role of dHAND in the anterior-posterior polarization of the limb bud: implications for the Sonic hedgehog pathway Development, May 15, 2000; 127(10): 2133 - 2142. [Abstract] [PDF]

				H Grandel, B. Draper, and S Schulte-Merker dackel acts in the ectoderm of the zebrafish pectoral fin bud to maintain AER signaling Development, January 10, 2000; 127(19): 4169 - 4178. [Abstract] [PDF]

				J Charite, D. McFadden, and E. Olson The bHLH transcription factor dHAND controls Sonic hedgehog expression and establishment of the zone of polarizing activity during limb development Development, January 6, 2000; 127(11): 2461 - 2470. [Abstract] [PDF]

				A. Moon, A. Boulet, and M. Capecchi Normal limb development in conditional mutants of Fgf4 Development, January 3, 2000; 127(5): 989 - 996. [Abstract] [PDF]

				J. Galceran, I. Fariñas, M. J. Depew, H. Clevers, and R. Grosschedl Wnt3a-/--like phenotype and limb deficiency in Lef1-/-Tcf1-/- mice Genes & Dev., March 15, 1999; 13(6): 709 - 717. [Abstract] [Full Text]

				C. Neumann, H Grandel, W Gaffield, S Schulte-Merker, and C Nusslein-Volhard Transient establishment of anteroposterior polarity in the zebrafish pectoral fin bud in the absence of sonic hedgehog activity Development, January 11, 1999; 126(21): 4817 - 4826. [Abstract] [PDF]

				R. Widelitz, T. Jiang, C. Chen, N. Stott, and C. Chuong Wnt-7a in feather morphogenesis: involvement of anterior-posterior asymmetry and proximal-distal elongation demonstrated with an in vitro reconstitution model Development, January 6, 1999; 126(12): 2577 - 2587. [Abstract] [PDF]

				A Zuniga and R Zeller Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity Development, January 1, 1999; 126(1): 13 - 21. [Abstract] [PDF]

				I Munoz-Sanjuan, B. Simandl, J. Fallon, and J Nathans Expression of chicken fibroblast growth factor homologous factor (FHF)-1 and of differentially spliced isoforms of FHF-2 during development and involvement of FHF-2 in chicken limb development Development, January 1, 1999; 126(2): 409 - 421. [Abstract] [PDF]

				G. R. Martin The roles of FGFs in the early development of vertebrate�limbs Genes & Dev., June 1, 1998; 12(11): 1571 - 1586. [Full Text]

				M Takahashi, K Tamura, D Buscher, H Masuya, S Yonei-Tamura, K Matsumoto, M Naitoh-Matsuo, J Takeuchi, K Ogura, T Shiroishi, et al. The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development Development, January 11, 1998; 125(22): 4417 - 4425. [Abstract] [PDF]

				C Rodriguez-Esteban, J. Schwabe, J. Pena, D. Rincon-Limas, J Magallon, J Botas, and J. Belmonte Lhx2, a vertebrate homologue of apterous, regulates vertebrate limb outgrowth Development, January 10, 1998; 125(20): 3925 - 3934. [Abstract] [PDF]

				F Reifers, H Bohli, E. Walsh, P. Crossley, D. Stainier, and M Brand Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of midbrain-hindbrain boundary development and somitogenesis Development, January 7, 1998; 125(13): 2381 - 2395. [Abstract] [PDF]

				C. Loomis, R. Kimmel, C. Tong, J Michaud, and A. Joyner Analysis of the genetic pathway leading to formation of ectopic apical ectodermal ridges in mouse Engrailed-1 mutant limbs Development, January 3, 1998; 125(6): 1137 - 1148. [Abstract] [PDF]

				X Xu, M Weinstein, C Li, M Naski, R. Cohen, D. Ornitz, P Leder, and C Deng Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction Development, January 2, 1998; 125(4): 753 - 765. [Abstract] [PDF]

				Y. Imokawa and K. Yoshizato Expression of Sonic hedgehog gene in regenerating newt limb blastemas recapitulates that in developing limb�buds PNAS, August 19, 1997; 94(17): 9159 - 9164. [Abstract] [Full Text] [PDF]

				T. Stratford, K Kostakopoulou, and M Maden Hoxb-8 has a role in establishing early anterior-posterior polarity in chick forelimb but not hindlimb Development, January 11, 1997; 124(21): 4225 - 4234. [Abstract] [PDF]

				V Knezevic, R De Santo, K Schughart, U Huffstadt, C Chiang, K. Mahon, and S Mackem Hoxd-12 differentially affects preaxial and postaxial chondrogenic branches in the limb and regulates Sonic hedgehog in a positive feedback loop Development, January 11, 1997; 124(22): 4523 - 4536. [Abstract] [PDF]

				M Altabef, J. Clarke, and C Tickle Dorso-ventral ectodermal compartments and origin of apical ectodermal ridge in developing chick limb Development, January 11, 1997; 124(22): 4547 - 4556. [Abstract] [PDF]

				H Ohuchi, T Nakagawa, A Yamamoto, A Araga, T Ohata, Y Ishimaru, H Yoshioka, T Kuwana, T Nohno, M Yamasaki, et al. The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor Development, January 6, 1997; 124(11): 2235 - 2244. [Abstract] [PDF]

				C Logan, A Hornbruch, I Campbell, and A Lumsden The role of Engrailed in establishing the dorsoventral axis of the chick limb Development, January 6, 1997; 124(12): 2317 - 2324. [Abstract] [PDF]

				M. Ros, M Sefton, and M. Nieto Slug, a zinc finger gene previously implicated in the early patterning of the mesoderm and the neural crest, is also involved in chick limb development Development, January 5, 1997; 124(9): 1821 - 1829. [Abstract] [PDF]

				J. Michaud, F Lapointe, and N. Le Douarin The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure Development, January 4, 1997; 124(8): 1453 - 1463. [Abstract] [PDF]

				M. Lewandoski, E.N. Meyers, and G.R. Martin Analysis of Fgf8 Gene Function in Vertebrate Development Cold Spring Harb Symp Quant Biol, January 1, 1997; 62(0): 159 - 168. [Abstract] [PDF]

				U Grieshammer, G Minowada, J. Pisenti, U. Abbott, and G. Martin The chick limbless mutation causes abnormalities in limb bud dorsal-ventral patterning: implications for the mechanism of apical ridge formation Development, January 12, 1996; 122(12): 3851 - 3861. [Abstract] [PDF]