Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Mo, R.
	Articles by Hui, C.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Mo, R.
	Articles by Hui, C.


Social Bookmarking

	What's this?

Bitgood, M. J. and McMahon, A. P (1995). Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev. Biol 172, 126-138.[Medline]

Chang, D. T. et al (1994). Products, genetic linkage and limb patterning activity of a murine hedgehog gene. Development 120, 3339-3353.[Abstract]

Christ, B. and Ordahl, C (1995). Early stages of chick somite development. Anat. Embryol 191, 381-396.[Medline]

Cohn, M. J. and Tickle, C (1996). Limbs: a model for pattern formation within the vertebrate body plan. Trends Genet 12, 253-257.[Medline]

Davis, A. P. and Capecchi, M. R (1996). A mutational analysis of the 5 HoxD genes: dissection of genetic interactions during limb development in the mouse. Development 122, 1175-1185.[Abstract]

Dietrich, S., Schubert, F. R. and Gruss, P (1993). Altered Pax gene expression in murine notochord mutants: The notochord is required to initiate and maintain ventral identity in the somite. Mech. Dev 44, 189-207.[Medline]

Dietrich, S. and Gruss, P (1995). undulated phenotypes suggest a role of Pax-1 for the development of vertebral and extravertebral structures. Dev. Biol 167, 529-548.[Medline]

Dolle, P., Izpisua-Belmonte, J.-C., Falkenstein, H., Renucci, A. and Duboule, D (1989). Coordinate expression of the murine Hox-5 complex homeobox-containing genes during limb pattern formation. Nature 342, 767-772.[Medline]

Dominguez, M., Brunner, M., Hafen, E. and Basler, K (1996). Sending and receiving the hedgehog signal: control by the Drosophila Gli protein cubitus interruptus. Science 272, 1621-1625.[Abstract]

Echelard, Y., Epstein, D. J., St.-Jauques, B., Shen, L., Mohler, J. A., McMahon, J. A. and McMahon, A. P (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.[Medline]

Erlebacher, A., Filvaroff, E., Gitelman, S. and Derynck, R (1995). Toward a molecular understanding of skeletal development. Cell 80, 371-378.[Medline]

Fan, C.-M. and Tessier-Lavigne, M (1994). Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog. Cell 79, 1175-1186.[Medline]

Fan, C.-M., Porter, J. A., Chiang, C., Chang, D. T., Beachy, P. and Tessier-Lavigne, M (1995). Long-range sclerotome induction by Sonic Hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. Cell 81, 457-465.[Medline]

Franz, T (1994). Extra-toes (Xt) homozygous mutant mice demonstrate a role for the Gli-3 gene in the development of the forebrain. Acta Anat 150, 38-44.[Medline]

Fromental-Ramain, C., Warot, X., Lakkaraju, S., Favier, B., Haack, H., Birling, C., Dierich, A., Dolle, P. and Chambon, P (1996). Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning. Development 122, 461-472.[Abstract]

Gollop, T. R. and Fontes, L.R (1985). The Greig cephalopolysyndactyly syndrome: Report of a family and review of the literature. Am. J. Med. Genet 22, 59-68.[Medline]

Goodrich, L. V., Johnson, R. L., Milenkovic, L., McMahon, J. A. and Scott, M. P (1996). Conservation of the hedgehog / patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog. Genes Dev 10, 301-312.[Abstract/Free Full Text]

Haack, H. and Gruss, P (1993). The establishment of murine Hox-1 expression domains during patterning of the limb. Dev. Biol 157, 410-422.[Medline]

Hahn, H. et al (1996). Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome. Cell 85, 841-851.[Medline]

Hammerschmidt, M., Bitgood, M. J. and McMahon, A. P (1996). Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. Genes Dev 10, 647-658.[Abstract/Free Full Text]

Hogan, B. L. M (1996). Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10, 1580-1594.[Free Full Text]

Hui, C.-c. and Joyner, A. L (1993). A mouse model of Greigcephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene. Nature Genet 3, 241-246.[Medline]

Hui, C.-c., Slusarski, D., Platt, K., Holmgren, R. and Joyner, A. L (1994). Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus , Gli , Gli-2 , and Gli-3 , in ectoderm-and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev. Biol 162, 402-413.[Medline]

Hynes, M., Porter, J. A., Chiang, C., Chang, D., Tessier-Lavigne, Beachy, P. A. and Rosenthal, A (1995). Induction of midbrain dopaminergic neurons by Sonic Hedgehog. Neuron 15, 35-44.[Medline]

Iseki, S., Araga, A., Ohuchi, H., Nohno, T., Yoshioka, H, Hayashi, F. and Noji, S (1996). Sonic hedgehog is expressed in epithelial cells during development of whsiker, hair, and tooth. Biochem. Biophys. Res. Comm 218, 688-693.[Medline]

Jegalian, B. G. and De Robertis, E. M (1992). Homeotic transformations in the mouse induced by overexpression of a human Hox3.3 transgene. Cell 71, 901-910.[Medline]

Johnson, D. R (1967). Extra-toes: a new mutant gene causing multiple abnormalities in the mouse. J. Embryol. Exp. Morph 17, 543-581.[Medline]

Johnson, R. L., Laufer, E., Riddle, R. D. and Tabin, C (1994). Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites. Cell 79, 1165-1173.[Medline]

Johnson, R. L., Grenier, J. and Scott, M. P (1995). Patched overexpression alters wing disc size and pattern: transcriptional and post-transcriptional effects on hedgehog targets. Development 121, 4161-4170.[Abstract]

Johnson, R. L. et al (1996). Human homolog of patched , a candidate gene for the basal cell nevus syndrome. Science 272, 1668-1671.[Abstract]

Koseki, H., Wallin, J., Wilting, J., Mizutani, Y., Ebensperger, C., Christ, B. and Balling, R (1993). Pax1 as a mediator of notochordal signals in the dorsoventral specification of vertebrae. Development 119, 649-660.[Abstract/Free Full Text]

Koyama, E. et al (1996). Polarizing activity, Sonic hedgehog , and tooth development in embryonic and postnatal mouse. Dev Dyn 206, 59-72.[Medline]

Lanske, B. et al (1996). PTH/PTHrP receptor in early development and Indian Hedgehog-regulated bone growth. Science 273, 663-666.[Abstract]

Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. and Tabin, C (1994). Sonic hedgehog and FGF-4 act througha signaling cascade and feedback loop to integrate growth and patterning on the developing limb. Cell 79, 993-1003.[Medline]

Lufkin, T., Mark, M., Hart, C. P., Dolle, P., LeMeur, M. and Chambon, P (1992). Homeotic transformation of the occipital bones of the skull by ectopic expression of a homeobox gene. Nature 359, 835-841.[Medline]

Margio, V., Scott, M. P., Johnson, R. L., Goodrich, L. V. and Tabin, C. J (1996). Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb. Development 122, 1225-1233.[Abstract]

Martin, J. F., Bradley, A. and Olson, E. N (1995). The paired -like homeo box gene MHox is required for early events of skeletogenesis in multiple lineages. Genes Dev 9, 1237-1249.[Abstract/Free Full Text]

Masuya, H., Sagai, T., Wakana, S., Moriwaki, K. and Shiroishi, T (1995). A duplicated zone of polarizing activity in polydactylous mouse mutants. Genes Dev 9, 1645-1653.[Abstract/Free Full Text]

Motzny, C.K. and Holmgren, R (1995). The Drosophila cubitus interruptus protein and its role in the wingless and hedgehog signal transduction pathways. Mech. Dev 52, 137-150.[Medline]

Nagy, A., Rossant, J., Nagy, R., Abramow-Newerly, W. and Roder, J (1994). Derivation of completely cell culture-derived mice form early-passage. Proc. Natl. Acad. Sci. USA 90, 8424-8428.[Abstract/Free Full Text]

Neubuser, A., Koseki, H. and Balling, R (1995). Characterization anddevelopmental expression of Pax9 , a paired-box-containing gene related to Pax1. Dev. Biol 170, 701-716.[Medline]

Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.[Medline]

Orenic, T. V., Slusarski, D. C., Kroll, K. L. and Holmgren, R. A (1990). Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila. Genes Dev 4, 1053-1067.[Abstract/Free Full Text]

Pavletich, N. P. and Pabo, C. O (1993). Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers. Science 261, 1701-1707.[Abstract/Free Full Text]

Riddle, R. D., Johnson, R. L., Laufer, E. and Tabin, C (1993). Sonic hedgehog mediates the polarizing activity of ZPA. Cell 75, 1401-1416.[Medline]

Roberts, D. J., Johnson, R. L., Burke, A. C., Nelson, C. E., Morgan, B. A. and Tabin, C (1995). Sonic hedgehog is an endodermal signal inducing Bmp-4 and Hox genes during induction and regionalization of the chick hindgut. Development 121, 3163-3174.[Abstract]

Satokata, I. and Maas, R (1994). Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development. Nature Genet 6, 348-355.[Medline]

Schimmang, T., Lemaistre, M., Vortkamp, A. and Ruther, U (1992). Expression of the zinc finger gene Gli3 is affected in the morphogenetic mouse mutant extra-toes ( Xt ). Development 116, 799-804.[Abstract]

Theiler, K (1988). Vertebral malformations. Adv. Anat. Embryol. Cell Biol 112, 1-99.[Medline]

Tybulewicz, V. L. J., Crawford, C. E., KJackson, P. K., Bronson, R. T. and Mulligan, R. C (1991). Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene. Cell 65, 1153-1163.[Medline]

Vaahtokari, A., Aberg, T., Jernvall, J., Keranen, S. and Thesleff, I (1996). The enamel knot as a signaling center in the developing mouse tooth. Mech. Dev 54, 39-43.[Medline]

Verbout, A. J (1985). The development of the vertebral column. Adv. Anat. Embryol. Cell Biol 90, 1-122.[Medline]

Vortkamp, A., Gessler, M. and Grzeschik, K.-H (1991). GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families. Nature 352, 539-540.[Medline]

Vortkamp, A., Franz, T., Gessler, M. and Grzeschik, K.-H (1992). Deletion of GLI3 supports the homology of the human Greig cephalopolysyndactyly syndrome (GCPS) and the mouse mutant extra toes (Xt). Mammalian Genome 3, 461-463.[Medline]

Vortkamp, A., Lee, K., Lanske, B., Serge, G. V., Kronenberg, H. M. and Tabin, C. J (1996). Regulation of rate of cartilage differentiation by Indian Hedgehog and PTH-related protein. Science 273, 613-622.[Abstract]

Wallin, J., Wilting, J., Koseki, H., Fritsch, R., Christ, B. and Balling, R (1994). The role of Pax1 in axial skeleton development. Development 120, 1109-1121.[Abstract]

Walterhouse, D., Ahmed, M., Slusarski, D., Kalamaras, J., Boucher, D., Holmgren, R. and Iannaccone, P (1993). gli , a putative zinc finger transcription factor, is expressed in a segmental pattern during normal mouse development. Dev. Dyn 196, 91-102.[Medline]

Zarkower, D. and Hodgkin, J (1993). Zinc fingers in sex determination: only one of the two C. elegans Tra-1 proteins binds DNA in vivo. Nucl.Acids Res 21, 3691-3698.[Abstract/Free Full Text]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

J. Han, J. Mayo, X. Xu, J. Li, P. Bringas Jr, R. L. Maas, J. L. R. Rubenstein, and Y. Chai
Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice
Development, December 15, 2009; 136(24): 4225 - 4233.
[Abstract] [Full Text] [PDF]

K. S. Joeng and F. Long
The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization
Development, December 15, 2009; 136(24): 4177 - 4185.
[Abstract] [Full Text] [PDF]

S. D. Weatherbee, L. A. Niswander, and K. V. Anderson
A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling
Hum. Mol. Genet., December 1, 2009; 18(23): 4565 - 4575.
[Abstract] [Full Text] [PDF]

S. Miyagawa, A. Moon, R. Haraguchi, C. Inoue, M. Harada, C. Nakahara, K. Suzuki, D. Matsumaru, T. Kaneko, I. Matsuo, et al.
Dosage-dependent hedgehog signals integrated with Wnt/{beta}-catenin signaling regulate external genitalia formation as an appendicular program
Development, December 1, 2009; 136(23): 3969 - 3978.
[Abstract] [Full Text] [PDF]

P. Purcell, B. W. Joo, J. K. Hu, P. V. Tran, M. L. Calicchio, D. J. O'Connell, R. L. Maas, and C. J. Tabin
Temporomandibular joint formation requires two distinct hedgehog-dependent steps
PNAS, October 27, 2009; 106(43): 18297 - 18302.
[Abstract] [Full Text] [PDF]

C. Anderson, S. Thorsteinsdottir, and A.-G. Borycki
Sonic hedgehog-dependent synthesis of laminin {alpha}1 controls basement membrane assembly in the myotome
Development, October 15, 2009; 136(20): 3495 - 3504.
[Abstract] [Full Text] [PDF]

M.-H. Chen, C. W. Wilson, Y.-J. Li, K. K. L. Law, C.-S. Lu, R. Gacayan, X. Zhang, C.-c. Hui, and P.-T. Chuang
Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
Genes & Dev., August 15, 2009; 23(16): 1910 - 1928.
[Abstract] [Full Text] [PDF]

M. I. Romero-Ortega and M. Ezaki
Nerve Pathology in Unregulated Limb Growth
J. Bone Joint Surg. Am., July 1, 2009; 91(Supplement_4): 53 - 57.
[Full Text] [PDF]

H. O.-L. Cheung, X. Zhang, A. Ribeiro, R. Mo, S. Makino, V. Puviindran, K. K. L. Law, J. Briscoe, and C.-c. Hui
The Kinesin Protein Kif7 Is a Critical Regulator of Gli Transcription Factors in Mammalian Hedgehog Signaling
Sci. Signal., June 23, 2009; 2(76): ra29 - ra29.
[Abstract] [Full Text] [PDF]

N. J. Rowbotham, A. L. Hager-Theodorides, A. L. Furmanski, S. E. Ross, S. V. Outram, J. T. Dessens, and T. Crompton
Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanism
Blood, May 21, 2009; 113(21): 5144 - 5156.
[Abstract] [Full Text] [PDF]

R. X. Norman, H. W. Ko, V. Huang, C. M. Eun, L. L. Abler, Z. Zhang, X. Sun, and J. T. Eggenschwiler
Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling
Hum. Mol. Genet., May 15, 2009; 18(10): 1740 - 1754.
[Abstract] [Full Text] [PDF]

Y. Ren, R. G. Cowan, R. M. Harman, and S. M. Quirk
Dominant Activation of the Hedgehog Signaling Pathway in the Ovary Alters Theca Development and Prevents Ovulation
Mol. Endocrinol., May 1, 2009; 23(5): 711 - 723.
[Abstract] [Full Text] [PDF]

Y. Lan and R. Jiang
Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth
Development, April 15, 2009; 136(8): 1387 - 1396.
[Abstract] [Full Text] [PDF]

M. Zhao, S.-Y. Ko, J.-H. Liu, D. Chen, J. Zhang, B. Wang, S. E. Harris, B. O. Oyajobi, and G. R. Mundy
Inhibition of Microtubule Assembly in Osteoblasts Stimulates Bone Morphogenetic Protein 2 Expression and Bone Formation through Transcription Factor Gli2
Mol. Cell. Biol., March 1, 2009; 29(5): 1291 - 1305.
[Abstract] [Full Text] [PDF]

B. B. Madison, L. B. McKenna, D. Dolson, D. J. Epstein, and K. H. Kaestner
FoxF1 and FoxL1 Link Hedgehog Signaling and the Control of Epithelial Proliferation in the Developing Stomach and Intestine
J. Biol. Chem., February 27, 2009; 284(9): 5936 - 5944.
[Abstract] [Full Text] [PDF]

D. S. Wall, A. J. Mears, B. McNeill, C. Mazerolle, S. Thurig, Y. Wang, R. Kageyama, and V. A. Wallace
Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity
J. Cell Biol., January 12, 2009; 184(1): 101 - 112.
[Abstract] [Full Text] [PDF]

W. T. Farmer, A. L. Altick, H. F. Nural, J. P. Dugan, T. Kidd, F. Charron, and G. S. Mastick
Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals
Development, November 15, 2008; 135(22): 3643 - 3653.
[Abstract] [Full Text] [PDF]

W. Yu, K. McDonnell, M. M. Taketo, and C. B. Bai
Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner
Development, November 15, 2008; 135(22): 3687 - 3696.
[Abstract] [Full Text] [PDF]

M. Varjosalo and J. Taipale
Hedgehog: functions and mechanisms
Genes & Dev., September 15, 2008; 22(18): 2454 - 2472.
[Abstract] [Full Text] [PDF]

T. Eichberger, A. Kaser, C. Pixner, C. Schmid, S. Klingler, M. Winklmayr, C. Hauser-Kronberger, F. Aberger, and A.-M. Frischauf
GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells
J. Biol. Chem., May 2, 2008; 283(18): 12426 - 12437.
[Abstract] [Full Text] [PDF]

S. Hartwig, D. Bridgewater, V. Di Giovanni, J. Cain, Y. Mishina, and N. D. Rosenblum
BMP Receptor ALK3 Controls Collecting System Development
J. Am. Soc. Nephrol., January 1, 2008; 19(1): 117 - 124.
[Abstract] [Full Text] [PDF]

M. C. Russell, R. G. Cowan, R. M. Harman, A. L. Walker, and S. M. Quirk
The Hedgehog Signaling Pathway in the Mouse Ovary
Biol Reprod, August 1, 2007; 77(2): 226 - 236.
[Abstract] [Full Text] [PDF]

A. Shimoyama, M. Wada, F. Ikeda, K. Hata, T. Matsubara, A. Nifuji, M. Noda, K. Amano, A. Yamaguchi, R. Nishimura, et al.
Ihh/Gli2 Signaling Promotes Osteoblast Differentiation by Regulating Runx2 Expression and Function
Mol. Biol. Cell, July 1, 2007; 18(7): 2411 - 2418.
[Abstract] [Full Text] [PDF]

B. L. Allen, T. Tenzen, and A. P. McMahon
The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development
Genes & Dev., May 15, 2007; 21(10): 1244 - 1257.
[Abstract] [Full Text] [PDF]

N. J. Rowbotham, A. L. Hager-Theodorides, M. Cebecauer, D. K. Shah, E. Drakopoulou, J. Dyson, S. V. Outram, and T. Crompton
Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation
Blood, May 1, 2007; 109(9): 3757 - 3766.
[Abstract] [Full Text] [PDF]

R. Haraguchi, J. Motoyama, H. Sasaki, Y. Satoh, S. Miyagawa, N. Nakagata, A. Moon, and G. Yamada
Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling
Development, February 1, 2007; 134(3): 525 - 533.
[Abstract] [Full Text] [PDF]

E. Nieuwenhuis, J. Motoyama, P. C. Barnfield, Y. Yoshikawa, X. Zhang, R. Mo, M. A. Crackower, and C.-c. Hui
Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia.
Mol. Cell. Biol., September 1, 2006; 26(17): 6609 - 6622.
[Abstract] [Full Text] [PDF]

S. Zhang, M. Shi, C.-c. Hui, and J. M. Rommens
Loss of the Mouse Ortholog of the Shwachman-Diamond Syndrome Gene (Sbds) Results in Early Embryonic Lethality.
Mol. Cell. Biol., September 1, 2006; 26(17): 6656 - 6663.
[Abstract] [Full Text] [PDF]

S. Warming, R. A. Rachel, N. A. Jenkins, and N. G. Copeland
Zfp423 is required for normal cerebellar development.
Mol. Cell. Biol., September 1, 2006; 26(18): 6913 - 6922.
[Abstract] [Full Text] [PDF]

M. Grachtchouk, J. Liu, A. Wang, L. Wei, C. K. Bichakjian, J. Garlick, A. F. Paulino, T. Giordano, and A. A. Dlugosz
Odontogenic Keratocysts Arise from Quiescent Epithelial Rests and Are Associated with Deregulated Hedgehog Signaling in Mice and Humans
Am. J. Pathol., September 1, 2006; 169(3): 806 - 814.
[Abstract] [Full Text] [PDF]

Y. Yang, C. L. Mahaffey, N. Berube, and W. N. Frankel
Interaction between Fidgetin and Protein Kinase A-anchoring Protein AKAP95 Is Critical for Palatogenesis in the Mouse
J. Biol. Chem., August 4, 2006; 281(31): 22352 - 22359.
[Abstract] [Full Text] [PDF]

M. Zhao, M. Qiao, S. E. Harris, D. Chen, B. O. Oyajobi, and G. R. Mundy
The zinc finger transcription factor gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling.
Mol. Cell. Biol., August 1, 2006; 26(16): 6197 - 6208.
[Abstract] [Full Text] [PDF]

C Shaw-Smith
Oesophageal atresia, tracheo-oesophageal fistula, and the VACTERL association: review of genetics and epidemiology
J. Med. Genet., July 1, 2006; 43(7): 545 - 554.
[Abstract] [Full Text] [PDF]

Y. Pan, C. B. Bai, A. L. Joyner, and B. Wang
Sonic hedgehog Signaling Regulates Gli2 Transcriptional Activity by Suppressing Its Processing and Degradation.
Mol. Cell. Biol., May 1, 2006; 26(9): 3365 - 3377.
[Abstract] [Full Text] [PDF]

S. Blaess, J. D. Corrales, and A. L. Joyner
Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region
Development, May 1, 2006; 133(9): 1799 - 1809.
[Abstract] [Full Text] [PDF]

J. D. Corrales, S. Blaess, E. M. Mahoney, and A. L. Joyner
The level of sonic hedgehog signaling regulates the complexity of cerebellar foliation
Development, May 1, 2006; 133(9): 1811 - 1821.
[Abstract] [Full Text] [PDF]

K. Watanabe, N. Tamamaki, T. Furuta, S. L. Ackerman, K. Ikenaka, and K. Ono
Dorsally derived netrin 1 provides an inhibitory cue and elaborates the `waiting period' for primary sensory axons in the developing spinal cord
Development, April 1, 2006; 133(7): 1379 - 1387.
[Abstract] [Full Text] [PDF]

M. C. Hu, R. Mo, S. Bhella, C. W. Wilson, P.-T. Chuang, C.-c. Hui, and N. D. Rosenblum
GLI3-dependent transcriptional repression of Gli1, Gli2 and kidney patterning genes disrupts renal morphogenesis
Development, February 1, 2006; 133(3): 569 - 578.
[Abstract] [Full Text] [PDF]

L. Koziel, M. Wuelling, S. Schneider, and A. Vortkamp
Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation
Development, December 1, 2005; 132(23): 5249 - 5260.
[Abstract] [Full Text] [PDF]

M. J. Hilton, X. Tu, J. Cook, H. Hu, and F. Long
Ihh controls cartilage development by antagonizing Gli3, but requires additional effectors to regulate osteoblast and vascular development
Development, October 1, 2005; 132(19): 4339 - 4351.
[Abstract] [Full Text] [PDF]

M.-H. Chen, N. Gao, T. Kawakami, and P.-T. Chuang
Mice Deficient in the Fused Homolog Do Not Exhibit Phenotypes Indicative of Perturbed Hedgehog Signaling during Embryonic Development
Mol. Cell. Biol., August 15, 2005; 25(16): 7042 - 7053.
[Abstract] [Full Text] [PDF]

A. L. Hager-Theodorides, J. T. Dessens, S. V. Outram, and T. Crompton
The transcription factor Gli3 regulates differentiation of fetal CD4-CD8- double-negative thymocytes
Blood, August 15, 2005; 106(4): 1296 - 1304.
[Abstract] [Full Text] [PDF]

E. Roessler, A. N. Ermilov, D. K. Grange, A. Wang, M. Grachtchouk, A. A. Dlugosz, and M. Muenke
A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2
Hum. Mol. Genet., August 1, 2005; 14(15): 2181 - 2188.
[Abstract] [Full Text] [PDF]

V. Stepan, S. Ramamoorthy, H. Nitsche, Y. Zavros, J. L. Merchant, and A. Todisco
Regulation and Function of the Sonic Hedgehog Signal Transduction Pathway in Isolated Gastric Parietal Cells
J. Biol. Chem., April 22, 2005; 280(16): 15700 - 15708.
[Abstract] [Full Text] [PDF]

A. McDermott, M. Gustafsson, T. Elsam, C.-C. Hui, C. P. Emerson Jr, and A.-G. Borycki
Gli2 and Gli3 have redundant and context-dependent function in skeletal muscle formation
Development, January 15, 2005; 132(2): 345 - 357.
[Abstract] [Full Text] [PDF]

M. E. Hutchin, M. S.T. Kariapper, M. Grachtchouk, A. Wang, L. Wei, D. Cummings, J. Liu, L. E. Michael, A. Glick, and A. A. Dlugosz
Sustained Hedgehog signaling is required for basal cell carcinoma proliferation and survival: conditional skin tumorigenesis recapitulates the hair growth cycle
Genes & Dev., January 15, 2005; 19(2): 214 - 223.
[Abstract] [Full Text] [PDF]

J. D. Corrales, G. L. Rocco, S. Blaess, Q. Guo, and A. L. Joyner
Spatial pattern of sonic hedgehog signaling through Gli genes during cerebellum development
Development, November 15, 2004; 131(22): 5581 - 5590.
[Abstract] [Full Text] [PDF]

B. Ganss and A. Jheon
ZINC FINGER TRANSCRIPTION FACTORS IN SKELETAL DEVELOPMENT
Critical Reviews in Oral Biology & Medicine, September 1, 2004; 15(5): 282 - 297.
[Abstract] [Full Text] [PDF]

Q. Lei, A. K. Zelman, E. Kuang, S. Li, and M. P. Matise
Transduction of graded Hedgehog signaling by a combination of Gli2 and Gli3 activator functions in the developing spinal cord
Development, August 1, 2004; 131(15): 3593 - 3604.
[Abstract] [Full Text] [PDF]

C. Wolff, S. Roy, K. E. Lewis, H. Schauerte, G. Joerg-Rauch, A. Kirn, C. Weiler, R. Geisler, P. Haffter, and P. W. Ingham
iguana encodes a novel zinc-finger protein with coiled-coil domains essential for Hedgehog signal transduction in the zebrafish embryo
Genes & Dev., July 1, 2004; 18(13): 1565 - 1576.
[Abstract] [Full Text] [PDF]

H. Petropoulos, P. J. Gianakopoulos, A. G. Ridgeway, and I. S. Skerjanc
Disruption of Meox or Gli Activity Ablates Skeletal Myogenesis in P19 Cells
J. Biol. Chem., June 4, 2004; 279(23): 23874 - 23881.
[Abstract] [Full Text] [PDF]

Y. Chen, V. Knezevic, V. Ervin, R. Hutson, Y. Ward, and S. Mackem
Direct interaction with Hoxd proteins reverses Gli3-repressor function to promote digit formation downstream of Shh
Development, May 15, 2004; 131(10): 2339 - 2347.
[Abstract] [Full Text] [PDF]

P. Stanier and G. E. Moore
Genetics of cleft lip and palate: syndromic genes contribute to the incidence of non-syndromic clefts
Hum. Mol. Genet., April 1, 2004; 13(suppl_1): R73 - R81.
[Abstract] [Full Text] [PDF]

V. Palma and A. R. i Altaba
Hedgehog-GLI signaling regulates the behavior of cells with stem cell properties in the developing neocortex
Development, January 15, 2004; 131(2): 337 - 345.
[Abstract] [Full Text] [PDF]

L. Buttitta, R. Mo, C.-C. Hui, and C.-M. Fan
Interplays of Gli2 and Gli3 and their requirement in mediating Shh-dependent sclerotome induction
Development, December 22, 2003; 130(25): 6233 - 6243.
[Abstract] [Full Text] [PDF]

M. Lebel, P. Agarwal, C. W. Cheng, M. G. Kabir, T. Y. Chan, V. Thanabalasingham, X. Zhang, D. R. Cohen, M. Husain, S. H. Cheng, et al.
The Iroquois Homeobox Gene Irx2 Is Not Essential for Normal Development of the Heart and Midbrain-Hindbrain Boundary in Mice
Mol. Cell. Biol., November 15, 2003; 23(22): 8216 - 8225.
[Abstract] [Full Text] [PDF]

E. Roessler, Y.-Z. Du, J. L. Mullor, E. Casas, W. P. Allen, G. Gillessen-Kaesbach, E. R. Roeder, J. E. Ming, A. R. i Altaba, and M. Muenke
Loss-of-function mutations in the human GLI2 gene are associated with pituitary anomalies and holoprosencephaly-like features
PNAS, November 11, 2003; 100(23): 13424 - 13429.
[Abstract] [Full Text] [PDF]

Y.-S. Kim, G. Nakanishi, M. Lewandoski, and A. M. Jetten
GLIS3, a novel member of the GLIS subfamily of Kruppel-like zinc finger proteins with repressor and activation functions
Nucleic Acids Res., October 1, 2003; 31(19): 5513 - 5525.
[Abstract] [Full Text] [PDF]

J. C.Y. Wong, N. Alon, C. Mckerlie, J. R. Huang, M. S. Meyn, and M. Buchwald
Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia
Hum. Mol. Genet., August 15, 2003; 12(16): 2063 - 2076.
[Abstract] [Full Text] [PDF]

R. O. Karlstrom, O. V. Tyurina, A. Kawakami, N. Nishioka, W. S. Talbot, H. Sasaki, and A. F. Schier
Genetic analysis of zebrafish gli1 and gli2 reveals divergent requirements for gli genes in vertebrate development
Development, April 15, 2003; 130(8): 1549 - 1564.
[Abstract] [Full Text] [PDF]

E. Roessler and M. Muenke
How a Hedgehog might see holoprosencephaly
Hum. Mol. Genet., April 2, 2003; 12(90001): R15 - 25.
[Abstract] [Full Text] [PDF]

C. B. Bai, W. Auerbach, J. S. Lee, D. Stephen, and A. L. Joyner
Gli2, but not Gli1, is required for initial Shh signaling and ectopic activation of the Shh pathway
Development, March 12, 2003; 129(20): 4753 - 4761.
[Abstract] [Full Text] [PDF]

M. Dunaeva, P. Michelson, P. Kogerman, and R. Toftgard
Characterization of the Physical Interaction of Gli Proteins with SUFU Proteins
J. Biol. Chem., February 7, 2003; 278(7): 5116 - 5122.
[Abstract] [Full Text] [PDF]

P. Mill, R. Mo, H. Fu, M. Grachtchouk, P. C.W. Kim, A. A. Dlugosz, and C.-c. Hui
Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development
Genes & Dev., January 15, 2003; 17(2): 282 - 294.
[Abstract] [Full Text] [PDF]

P. Dai, T. Shinagawa, T. Nomura, J. Harada, S. C. Kaul, R. Wadhwa, M. M. Khan, H. Akimaru, H. Sasaki, C. Colmenares, et al.
Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3
Genes & Dev., November 15, 2002; 16(22): 2843 - 2848.
[Abstract] [Full Text] [PDF]

M. Persson, D. Stamataki, P. te Welscher, E. Andersson, J. Bose, U. Ruther, J. Ericson, and J. Briscoe
Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity
Genes & Dev., November 15, 2002; 16(22): 2865 - 2878.
[Abstract] [Full Text] [PDF]

H. Sheng, S. Goich, A. Wang, M. Grachtchouk, L. Lowe, R. Mo, K. Lin, F. J. de Sauvage, H. Sasaki, C.-c. Hui, et al.
Dissecting the Oncogenic Potential of Gli2: Deletion of an NH2-Terminal Fragment Alters Skin Tumor Phenotype
Cancer Res., September 15, 2002; 62(18): 5308 - 5316.
[Abstract] [Full Text] [PDF]

Y.-S. Kim, M. Lewandoski, A. O. Perantoni, S. Kurebayashi, G. Nakanishi, and A. M. Jetten
Identification of Glis1, a Novel Gli-related, Kruppel-like Zinc Finger Protein Containing Transactivation and Repressor Functions
J. Biol. Chem., August 16, 2002; 277(34): 30901 - 30913.
[Abstract] [Full Text] [PDF]

F. Zhang, G. Nakanishi, S. Kurebayashi, K. Yoshino, A. Perantoni, Y.-S. Kim, and A. M. Jetten
Characterization of Glis2, a Novel Gene Encoding a Gli-related, Kruppel-like Transcription Factor with Transactivation and Repressor Functions. ROLES IN KIDNEY DEVELOPMENT AND NEUROGENESIS
J. Biol. Chem., March 15, 2002; 277(12): 10139 - 10149.
[Abstract] [Full Text] [PDF]

J. W. Yoon, Y. Kita, D. J. Frank, R. R. Majewski, B. A. Konicek, M. A. Nobrega, H. Jacob, D. Walterhouse, and P. Iannaccone
Gene Expression Profiling Leads to Identification of GLI1-binding Elements in Target Genes and a Role for Multiple Downstream Pathways in GLI1-induced Cell Transformation
J. Biol. Chem., February 8, 2002; 277(7): 5548 - 5555.
[Abstract] [Full Text] [PDF]

J. Chen and D. E. Harrison
Quantitative trait loci regulating relative lymphocyte proportions in mouse peripheral blood
Blood, January 15, 2002; 99(2): 561 - 566.
[Abstract] [Full Text] [PDF]

M. K. Gustafsson, H. Pan, D. F. Pinney, Y. Liu, A. Lewandowski, D. J. Epstein, and C. P. Emerson Jr.
Myf5 is a direct target of long-range Shh signaling and Gli regulation for muscle specification
Genes & Dev., January 1, 2002; 16(1): 114 - 126.
[Abstract] [Full Text] [PDF]

N. Sato, P. L. Leopold, and R. G. Crystal
Effect of Adenovirus-Mediated Expression of Sonic Hedgehog Gene on Hair Regrowth in Mice With Chemotherapy-Induced Alopecia
J Natl Cancer Inst, December 19, 2001; 93(24): 1858 - 1864.
[Abstract] [Full Text] [PDF]

C. B. Bai and A. L. Joyner
Gli1 can rescue the in vivo function of Gli2
Development, December 15, 2001; 128(24): 5161 - 5172.
[Abstract] [Full Text] [PDF]

R. Haraguchi, R. Mo, C.-c. Hui, J. Motoyama, S. Makino, T. Shiroishi, W. Gaffield, and G. Yamada
Unique functions of Sonic hedgehog signaling during external genitalia development
Development, November 1, 2001; 128(21): 4241 - 4250.
[Abstract] [Full Text] [PDF]

R. Mo, J. H. Kim, J. Zhang, C. Chiang, C.-c. Hui, and P. C. W. Kim
Anorectal Malformations Caused by Defects in Sonic Hedgehog Signaling
Am. J. Pathol., August 1, 2001; 159(2): 765 - 774.
[Abstract] [Full Text]

R. H. Costa, V. V. Kalinichenko, and L. Lim
Transcription factors in mouse lung development and function
Am J Physiol Lung Cell Mol Physiol, May 1, 2001; 280(5): L823 - L838.
[Abstract] [Full Text] [PDF]

M. Dundar, T. M Gordon, I. Ozyazgan, F. Oguzkaya, Y. Ozkul, A. Cooke, A G. Wilkinson, S. Holloway, F. R Goodman, and J. L Tolmie
A novel acropectoral syndrome maps to chromosome 7q36
J. Med. Genet., May 1, 2001; 38(5): 304 - 309.
[Abstract] [Full Text]

M. J. Smith, S. D. Gitlin, C. M. Browning, B. R. Lane, N. M. Clark, N. Shah, S. Rainier, and D. M. Markovitz
GLI-2 Modulates Retroviral Gene Expression
J. Virol., March 1, 2001; 75(5): 2301 - 2313.
[Abstract] [Full Text]

C. M. Browning, M. J. Smith, N. M. Clark, B. R. Lane, C. Parada, M. Montano, V. N. KewalRamani, D. R. Littman, M. Essex, R. G. Roeder, et al.
Human GLI-2 Is a Tat Activation Response Element-Independent Tat Cofactor
J. Virol., March 1, 2001; 75(5): 2314 - 2323.
[Abstract] [Full Text]

C. P. Klingenberg, L. J. Leamy, E. J. Routman, and J. M. Cheverud
Genetic Architecture of Mandible Shape in Mice: Effects of Quantitative Trait Loci Analyzed by Geometric Morphometrics
Genetics, February 1, 2001; 157(2): 785 - 802.
[Abstract] [Full Text]

M. Mina
Regulation of Mandibular Growth and Morphogenesis
Critical Reviews in Oral Biology & Medicine, January 1, 2001; 12(4): 276 - 300.
[Abstract] [Full Text] [PDF]

D. Epstein, L Martinu, J. Michaud, K. Losos, C Fan, and A. Joyner
Members of the bHLH-PAS family regulate Shh transcription in forebrain regions of the mouse CNS
Development, January 11, 2000; 127(21): 4701 - 4709.
[Abstract] [PDF]

R Brewster, J. Mullor, and A Ruiz i Altaba
Gli2 functions in FGF signaling during antero-posterior patterning
Development, January 10, 2000; 127(20): 4395 - 4405.
[Abstract] [PDF]

H. Park, C Bai, K. Platt, M. Matise, A Beeghly, C. Hui, M Nakashima, and A. Joyner
Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation
Development, January 4, 2000; 127(8): 1593 - 1605.
[Abstract] [PDF]

S. Baur, J. Mai, and S. Dymecki
Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity
Development, January 2, 2000; 127(3): 605 - 619.
[Abstract] [PDF]

T. L. McCarthy, Changhua Ji, and M. Centrella
Links Among Growth Factors, Hormones, and Nuclear Factors With Essential Roles in Bone Formation
Critical Reviews in Oral Biology & Medicine, January 1, 2000; 11(4): 409 - 422.
[Abstract] [Full Text] [PDF]

M. Kalff-Suske, A. Wild, J. Topp, M. Wessling, E.-M. Jacobsen, D. Bornholdt, H. Engel, H. Heuer, C. M. Aalfs, M. G. E. M. Ausems, et al.
Point mutations throughout the GLI3 gene cause Greig cephalopolysyndactyly syndrome
Hum. Mol. Genet., September 1, 1999; 8(9): 1769 - 1777.
[Abstract] [Full Text] [PDF]

L. A. Lettice, L. A. Purdie, G. J. Carlson, F. Kilanowski, J. Dorin, and R. E. Hill
The mouse bagpipe gene controls development of axial skeleton, skull, and spleen
PNAS, August 17, 1999; 96(17): 9695 - 9700.
[Abstract] [Full Text] [PDF]

M. Iwamoto, M. Enomoto-Iwamoto, and K. Kurisu
Actions of Hedgehog Proteins on Skeletal Cells
Critical Reviews in Oral Biology & Medicine, July 1, 1999; 10(4): 477 - 486.
[Abstract] [Full Text] [PDF]

P. Dai, H. Akimaru, Y. Tanaka, T. Maekawa, M. Nakafuku, and S. Ishii
Sonic Hedgehog-induced Activation of the Gli1 Promoter Is Mediated by GLI3
J. Biol. Chem., March 19, 1999; 274(12): 8143 - 8152.
[Abstract] [Full Text] [PDF]

D. Stone, M Murone, S Luoh, W Ye, M. Armanini, A Gurney, H Phillips, J Brush, A Goddard, F. de Sauvage, et al.
Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
J. Cell Sci., January 12, 1999; 112(23): 4437 - 4448.
[Abstract] [PDF]

H Peters, B Wilm, N Sakai, K Imai, R Maas, and R Balling
Pax1 and Pax9 synergistically regulate vertebral column development
Development, January 12, 1999; 126(23): 5399 - 5408.
[Abstract] [PDF]

Y Taya, S O'Kane, and M. Ferguson
Pathogenesis of cleft palate in TGF-beta3 knockout mice
Development, January 9, 1999; 126(17): 3869 - 3879.
[Abstract] [PDF]

T Theil, G Alvarez-Bolado, A Walter, and U Ruther
Gli3 is required for Emx gene expression during dorsal telencephalon development
Development, January 8, 1999; 126(16): 3561 - 3571.
[Abstract] [PDF]

M. Matise, M Lustig, T Sakurai, M Grumet, and A. Joyner
Ventral midline cells are required for the local control of commissural axon guidance in the mouse spinal cord
Development, January 8, 1999; 126(16): 3649 - 3659.
[Abstract] [PDF]

A Ruiz i Altaba
Gli proteins encode context-dependent positive and negative functions: implications for development and disease
Development, January 6, 1999; 126(14): 3205 - 3216.
[Abstract] [PDF]

S Qu, S. Tucker, Q Zhao, B deCrombrugghe, and R Wisdom
Physical and genetic interactions between Alx4 and Cart1
Development, January 1, 1999; 126(2): 359 - 369.
[Abstract] [PDF]

R. Jiang, Y. Lan, H. D. Chapman, C. Shawber, C. R. Norton, D. V. Serreze, G. Weinmaster, and T. Gridley
Defects in limb, craniofacial, and thymic development in Jagged2 mutant�mice
Genes & Dev., April 1, 1998; 12(7): 1046 - 1057.
[Abstract] [Full Text]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Mo, R.

Articles by Hui, C.

Search for Related Content

PubMed

PubMed Citation

Articles by Mo, R.

Articles by Hui, C.

Social Bookmarking

What's this?

				K. S. Joeng and F. Long The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization Development, December 15, 2009; 136(24): 4177 - 4185. [Abstract] [Full Text] [PDF]

				S. D. Weatherbee, L. A. Niswander, and K. V. Anderson A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling Hum. Mol. Genet., December 1, 2009; 18(23): 4565 - 4575. [Abstract] [Full Text] [PDF]

				S. Miyagawa, A. Moon, R. Haraguchi, C. Inoue, M. Harada, C. Nakahara, K. Suzuki, D. Matsumaru, T. Kaneko, I. Matsuo, et al. Dosage-dependent hedgehog signals integrated with Wnt/{beta}-catenin signaling regulate external genitalia formation as an appendicular program Development, December 1, 2009; 136(23): 3969 - 3978. [Abstract] [Full Text] [PDF]

				P. Purcell, B. W. Joo, J. K. Hu, P. V. Tran, M. L. Calicchio, D. J. O'Connell, R. L. Maas, and C. J. Tabin Temporomandibular joint formation requires two distinct hedgehog-dependent steps PNAS, October 27, 2009; 106(43): 18297 - 18302. [Abstract] [Full Text] [PDF]

				C. Anderson, S. Thorsteinsdottir, and A.-G. Borycki Sonic hedgehog-dependent synthesis of laminin {alpha}1 controls basement membrane assembly in the myotome Development, October 15, 2009; 136(20): 3495 - 3504. [Abstract] [Full Text] [PDF]

				M.-H. Chen, C. W. Wilson, Y.-J. Li, K. K. L. Law, C.-S. Lu, R. Gacayan, X. Zhang, C.-c. Hui, and P.-T. Chuang Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved Genes & Dev., August 15, 2009; 23(16): 1910 - 1928. [Abstract] [Full Text] [PDF]

				M. I. Romero-Ortega and M. Ezaki Nerve Pathology in Unregulated Limb Growth J. Bone Joint Surg. Am., July 1, 2009; 91(Supplement_4): 53 - 57. [Full Text] [PDF]

				H. O.-L. Cheung, X. Zhang, A. Ribeiro, R. Mo, S. Makino, V. Puviindran, K. K. L. Law, J. Briscoe, and C.-c. Hui The Kinesin Protein Kif7 Is a Critical Regulator of Gli Transcription Factors in Mammalian Hedgehog Signaling Sci. Signal., June 23, 2009; 2(76): ra29 - ra29. [Abstract] [Full Text] [PDF]

				N. J. Rowbotham, A. L. Hager-Theodorides, A. L. Furmanski, S. E. Ross, S. V. Outram, J. T. Dessens, and T. Crompton Sonic hedgehog negatively regulates pre-TCR-induced differentiation by a Gli2-dependent mechanism Blood, May 21, 2009; 113(21): 5144 - 5156. [Abstract] [Full Text] [PDF]

				R. X. Norman, H. W. Ko, V. Huang, C. M. Eun, L. L. Abler, Z. Zhang, X. Sun, and J. T. Eggenschwiler Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling Hum. Mol. Genet., May 15, 2009; 18(10): 1740 - 1754. [Abstract] [Full Text] [PDF]

				Y. Ren, R. G. Cowan, R. M. Harman, and S. M. Quirk Dominant Activation of the Hedgehog Signaling Pathway in the Ovary Alters Theca Development and Prevents Ovulation Mol. Endocrinol., May 1, 2009; 23(5): 711 - 723. [Abstract] [Full Text] [PDF]

				Y. Lan and R. Jiang Sonic hedgehog signaling regulates reciprocal epithelial-mesenchymal interactions controlling palatal outgrowth Development, April 15, 2009; 136(8): 1387 - 1396. [Abstract] [Full Text] [PDF]

				M. Zhao, S.-Y. Ko, J.-H. Liu, D. Chen, J. Zhang, B. Wang, S. E. Harris, B. O. Oyajobi, and G. R. Mundy Inhibition of Microtubule Assembly in Osteoblasts Stimulates Bone Morphogenetic Protein 2 Expression and Bone Formation through Transcription Factor Gli2 Mol. Cell. Biol., March 1, 2009; 29(5): 1291 - 1305. [Abstract] [Full Text] [PDF]

				B. B. Madison, L. B. McKenna, D. Dolson, D. J. Epstein, and K. H. Kaestner FoxF1 and FoxL1 Link Hedgehog Signaling and the Control of Epithelial Proliferation in the Developing Stomach and Intestine J. Biol. Chem., February 27, 2009; 284(9): 5936 - 5944. [Abstract] [Full Text] [PDF]

				D. S. Wall, A. J. Mears, B. McNeill, C. Mazerolle, S. Thurig, Y. Wang, R. Kageyama, and V. A. Wallace Progenitor cell proliferation in the retina is dependent on Notch-independent Sonic hedgehog/Hes1 activity J. Cell Biol., January 12, 2009; 184(1): 101 - 112. [Abstract] [Full Text] [PDF]

				W. T. Farmer, A. L. Altick, H. F. Nural, J. P. Dugan, T. Kidd, F. Charron, and G. S. Mastick Pioneer longitudinal axons navigate using floor plate and Slit/Robo signals Development, November 15, 2008; 135(22): 3643 - 3653. [Abstract] [Full Text] [PDF]

				W. Yu, K. McDonnell, M. M. Taketo, and C. B. Bai Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner Development, November 15, 2008; 135(22): 3687 - 3696. [Abstract] [Full Text] [PDF]

				M. Varjosalo and J. Taipale Hedgehog: functions and mechanisms Genes & Dev., September 15, 2008; 22(18): 2454 - 2472. [Abstract] [Full Text] [PDF]

				T. Eichberger, A. Kaser, C. Pixner, C. Schmid, S. Klingler, M. Winklmayr, C. Hauser-Kronberger, F. Aberger, and A.-M. Frischauf GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells J. Biol. Chem., May 2, 2008; 283(18): 12426 - 12437. [Abstract] [Full Text] [PDF]

				S. Hartwig, D. Bridgewater, V. Di Giovanni, J. Cain, Y. Mishina, and N. D. Rosenblum BMP Receptor ALK3 Controls Collecting System Development J. Am. Soc. Nephrol., January 1, 2008; 19(1): 117 - 124. [Abstract] [Full Text] [PDF]

				M. C. Russell, R. G. Cowan, R. M. Harman, A. L. Walker, and S. M. Quirk The Hedgehog Signaling Pathway in the Mouse Ovary Biol Reprod, August 1, 2007; 77(2): 226 - 236. [Abstract] [Full Text] [PDF]

				A. Shimoyama, M. Wada, F. Ikeda, K. Hata, T. Matsubara, A. Nifuji, M. Noda, K. Amano, A. Yamaguchi, R. Nishimura, et al. Ihh/Gli2 Signaling Promotes Osteoblast Differentiation by Regulating Runx2 Expression and Function Mol. Biol. Cell, July 1, 2007; 18(7): 2411 - 2418. [Abstract] [Full Text] [PDF]

				B. L. Allen, T. Tenzen, and A. P. McMahon The Hedgehog-binding proteins Gas1 and Cdo cooperate to positively regulate Shh signaling during mouse development Genes & Dev., May 15, 2007; 21(10): 1244 - 1257. [Abstract] [Full Text] [PDF]

				R. Haraguchi, J. Motoyama, H. Sasaki, Y. Satoh, S. Miyagawa, N. Nakagata, A. Moon, and G. Yamada Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling Development, February 1, 2007; 134(3): 525 - 533. [Abstract] [Full Text] [PDF]

				E. Nieuwenhuis, J. Motoyama, P. C. Barnfield, Y. Yoshikawa, X. Zhang, R. Mo, M. A. Crackower, and C.-c. Hui Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia. Mol. Cell. Biol., September 1, 2006; 26(17): 6609 - 6622. [Abstract] [Full Text] [PDF]

				S. Zhang, M. Shi, C.-c. Hui, and J. M. Rommens Loss of the Mouse Ortholog of the Shwachman-Diamond Syndrome Gene (Sbds) Results in Early Embryonic Lethality. Mol. Cell. Biol., September 1, 2006; 26(17): 6656 - 6663. [Abstract] [Full Text] [PDF]

				S. Warming, R. A. Rachel, N. A. Jenkins, and N. G. Copeland Zfp423 is required for normal cerebellar development. Mol. Cell. Biol., September 1, 2006; 26(18): 6913 - 6922. [Abstract] [Full Text] [PDF]

				M. Grachtchouk, J. Liu, A. Wang, L. Wei, C. K. Bichakjian, J. Garlick, A. F. Paulino, T. Giordano, and A. A. Dlugosz Odontogenic Keratocysts Arise from Quiescent Epithelial Rests and Are Associated with Deregulated Hedgehog Signaling in Mice and Humans Am. J. Pathol., September 1, 2006; 169(3): 806 - 814. [Abstract] [Full Text] [PDF]

				Y. Yang, C. L. Mahaffey, N. Berube, and W. N. Frankel Interaction between Fidgetin and Protein Kinase A-anchoring Protein AKAP95 Is Critical for Palatogenesis in the Mouse J. Biol. Chem., August 4, 2006; 281(31): 22352 - 22359. [Abstract] [Full Text] [PDF]

				M. Zhao, M. Qiao, S. E. Harris, D. Chen, B. O. Oyajobi, and G. R. Mundy The zinc finger transcription factor gli2 mediates bone morphogenetic protein 2 expression in osteoblasts in response to hedgehog signaling. Mol. Cell. Biol., August 1, 2006; 26(16): 6197 - 6208. [Abstract] [Full Text] [PDF]