spacer gif spacer gif spacer gif spacer gif spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zhong, W.
Right arrow Articles by Jan, Y. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhong, W.
Right arrow Articles by Jan, Y. N.
Artavanis-Tsakonas, S., Matsuno, K. and Fortini, M. E (1995). Notch signaling. Science 268, 225-232.[Abstract/Free Full Text]

Brand, A. H. and Perrimon, N (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.[Abstract]

Caviness, V. S., Jr., Takahashi, T. and Nowakowski, R. S (1995). Numbers, time and neocortical neurogenesis: a general developmental and evolutionary model. Trends Neurosci 18, 379-383.[Medline]

Chenn, A. and McConnell, S. K (1995). Cleavage orientation and the asymmetric inheritance of Notch1 immunoreactivity in mammalian neurogenesis. Cell 82, 631-641.[Medline]

Church, G. M. and Gilbert, W (1984). Genomic sequencing. Proc. Natl. Acad. Sci. USA 81, 1991-1995.[Abstract/Free Full Text]

del Amo, F. F., Gendron-Maguire, M., Swiatek, P. J., Jenkins, N. A., Copeland, N. G. and Gridley, T (1993). Cloning, analysis, and chromosomal localization of Notch1 , a mouse homolog of Drosophila Notch. Genomics 15, 259-264.[Medline]

Duncan, S. A., Manova, K., Chen, W. S., Hoodless, P., Weinstein, D. C., Bachvarova, R. F. and Dranell, J. R., Jr (1994). Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. Proc. Natl. Acad. Sci. USA 91, 7598-7602.[Abstract/Free Full Text]

Fortini, M. E., Rebay, I., Caron, L. A. and Artavanis-Tsakonas, S (1993). An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye. Nature 365, 555-557.[Medline]

Frise, E., Knoblich, J. A., Younger-Shepherd, S., Jan, L. Y. and Jan, Y. N (1996). The Drosophila Numb protein inhibits signaling of the Notch receptor during cell-cell interactions in sensory organ lineage. Proc. Natl. Acad. Sci. USA 93, 11925-11932.[Abstract/Free Full Text]

Ghosh, A. and Greenberg, M. E (1995). Distinct roles for bFGF and NT-3 in the regulation of cortical neurogenesis. Neuron 15, 89-103.[Medline]

Guo, M., Jan, L. Y. and Jan, Y. N (1996). Control of daughter cell fates during asymmetric division: interaction of Numb and Notch. Neuron 17, 27-41.[Medline]

Hartenstein, V. and Posakony, J. W (1990). A dual function of the Notch gene in Drosophila sensillum development. Dev. Biol 142, 13-30.[Medline]

Jan, Y. N. and Jan, L. Y (1995). Maggot's hair and bug's eye: role of cell interactions and intrinsic factors in cell fate specification. Neuron 14, 1-5.[Medline]

Kornack, D. R. and Rakic, P (1995). Radial and horizontal deployment of clonally related cells in the primate neocortex: relationship to distinct mitotic lineages. Neuron 15, 311-321.[Medline]

Lardelli, M., Dahlstrand, J. and Lendahl, U (1994). The novel Notch homologue mouse Notch3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium. Mech. Dev 46, 123-136.[Medline]

Luskin, M. B., Pearlman, A. L. and Sanes, J. R (1988). Cell lineage in the cerebral cortex of the mouse studied in vivo and in vitro with a recombinant retrovirus. Neuron 1, 635-647.[Medline]

McConnell, S. K (1995). Constructing the cerebral cortex: neurogenesis and fate determination. Neuron 15, 761-768.[Medline]

Price, J. and Thurlow, L (1988). Cell lineage in the rat cerebral cortex: a study using retroviral-mediated gene transfer. Development 104, 473-482.[Abstract/Free Full Text]

Rakic, P (1988). Specification of cerebral cortical areas. Science 241, 170-176.[Abstract/Free Full Text]

Rakic, P (1995). Radial versus tangential migration of neuronal clones in the developing cerebral cortex. Proc. Natl. Acad. Sci. USA 92, 11323-11327.[Free Full Text]

Reid, C. B., Liang, I. and Walsh, C (1995). Systematic widespread clonal organization in cerebral cortex. Neuron 15, 299-310.[Medline]

Rhyu, M. S., Jan, L. Y. and Jan, Y. N (1994). Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76, 477-491.[Medline]

Ross, C. A (1995). When more is less: pathogenesis of glutamine repeat neurodegenerative diseases. Neuron 15, 493-496.[Medline]

Schaeren-Wiemers, N. and Gerfin-Moser, A (1993). A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situhybridization using digoxigenin-labeled cRNA probes. Histochemistry 100, 431-440.[Medline]

Spana, E. P. and Doe, C. Q (1996). Numb antagonizes Notch signaling to specify sibling neuron cell fates. Neuron 17, 21-26.[Medline]

Spana, E. P., Kopczynski, C., Goodman, C. S. and Doe, C. Q (1995). Asymmetric localization of numb autonomously determines sibling neuron identity in the Drosophila CNS. Development 121, 3489-3494.[Abstract]

Struhl, G., Fitzgerald, K. and Greenwald, I (1993). Intrinsic activity of the Lin-12 and Notch intracellular domains in vivo. Cell 74, 331-345.[Medline]

Uemura, T., Shepherd, S., Ackerman, L., Jan, L. Y. and Jan, Y. N (1989). numb , a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 58, 349-360.[Medline]

Verdi, J. M., Schmandt, R., Bashirullah, A., Jacob, S., Salvino, R., Craig, C. G., Amgen EST Program, Lipshitz, H. D. and McGlade, C. J (1996). Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate. Curr. Biol 6, 1134-1145.[Medline]

Vicario-Abejon, C., Johe, K. K., Hazel, T. G., Collazo, D. and McKay, R. D. G (1995). Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Neuron 15, 105-114.[Medline]

Walsh, C. and Cepko, C. L (1988). Clonally related cortical cells show several migration patterns. Science 241, 1342-1345.[Abstract/Free Full Text]

Weinmaster, G., Roberts, V. J. and Lemke, G (1991). A homolog of Drosophila Notch expressed during mammalian development. Development 113, 199-205.[Abstract]

Weinmaster, G., Roberts, V. J. and Lemke, G (1992). Notch2 : a second mammalian Notch gene. Development 116, 931-941.[Abstract]

Zhong, W., Feder, J. N., Jiang, M.-M., Jan, L. Y. and Jan, Y. N (1996). Asymmetric localization of a mammalian Numb homologue during mouse cortical neurogenesis. Neuron 17, 43-53.[Medline]

Zhong, W., Mirkovitch, J. and Darnell, J. E., Jr (1994). Tissue specific regulation of mouse hepatocyte nuclear factor 4 expression. Mol. Cell. Biol 14, 7276-7284.[Abstract/Free Full Text]

Zhou, M.-M., Ravichandran, K. S., Olejniczak, E. T., Petros, A. M., Meadows, R. P., Sattler, M., Harlan, J. E., Wade, W. S., Burakoff, S. J. and Fesik, S. W (1995). Structure and ligand recognition of the phosphotyrosine binding domain of Shc. Nature 378, 584-592.[Medline]




This article has been cited by other articles:


Home page
DevelopmentHome page
R. C. Range, T. D. Glenn, E. Miranda, and D. R. McClay
LvNumb works synergistically with Notch signaling to specify non-skeletal mesoderm cells in the sea urchin embryo
Development, July 15, 2008; 135(14): 2445 - 2454.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
A. Wilson, D.-L. Ardiet, C. Saner, N. Vilain, F. Beermann, M. Aguet, H. R. MacDonald, and O. Zilian
Normal Hemopoiesis and Lymphopoiesis in the Combined Absence of Numb and Numblike
J. Immunol., June 1, 2007; 178(11): 6746 - 6751.
[Abstract] [Full Text] [PDF]


Home page
ReproductionHome page
S. Corallini, S. Fera, L. Grisanti, I. Falciatori, B. Muciaccia, M. Stefanini, and E. Vicini
Expression of the adaptor protein m-Numb in mouse male germ cells.
Reproduction, December 1, 2006; 132(6): 887 - 897.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
G. Chapman, L. Liu, C. Sahlgren, C. Dahlqvist, and U. Lendahl
High levels of Notch signaling down-regulate Numb and Numblike
J. Cell Biol., November 20, 2006; 175(4): 535 - 540.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
L. S. Campos, L. Decker, V. Taylor, and W. Skarnes
Notch, Epidermal Growth Factor Receptor, and beta1-Integrin Pathways Are Coordinated in Neural Stem Cells
J. Biol. Chem., February 24, 2006; 281(8): 5300 - 5309.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
M. Sakurai, K. Ayukawa, R. Setsuie, K. Nishikawa, Y. Hara, H. Ohashi, M. Nishimoto, T. Abe, Y. Kudo, M. Sekiguchi, et al.
Ubiquitin C-terminal hydrolase L1 regulates the morphology of neural progenitor cells and modulates their differentiation
J. Cell Sci., January 1, 2006; 119(1): 162 - 171.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
L. Poggi, M. Vitorino, I. Masai, and W. A. Harris
Influences on neural lineage and mode of division in the zebrafish retina in vivo
J. Cell Biol., December 19, 2005; 171(6): 991 - 999.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
H. Tokumitsu, N. Hatano, H. Inuzuka, Y. Sueyoshi, S. Yokokura, T. Ichimura, N. Nozaki, and R. Kobayashi
Phosphorylation of Numb Family Proteins: POSSIBLE INVOLVEMENT OF CA2+/CALMODULIN-DEPENDENT PROTEIN KINASES
J. Biol. Chem., October 21, 2005; 280(42): 35108 - 35118.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
H. Tang, S. B. Rompani, J. B. Atkins, Y. Zhou, T. Osterwalder, and W. Zhong
Numb Proteins Specify Asymmetric Cell Fates via an Endocytosis- and Proteasome-Independent Pathway
Mol. Cell. Biol., April 15, 2005; 25(8): 2899 - 2909.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
T. Melkman and P. Sengupta
Regulation of chemosensory and GABAergic motor neuron development by the C. elegans Aristaless/Arx homolog alr-1
Development, April 15, 2005; 132(8): 1935 - 1949.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
R. Ben-Yair and C. Kalcheim
Lineage analysis of the avian dermomyotome sheet reveals the existence of single cells with both dermal and muscle progenitor fates
Development, February 15, 2005; 132(4): 689 - 701.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
A. C. Anderson, E. A. Kitchens, S. W. Chan, C. St. Hill, Y. N. Jan, W. Zhong, and E. A. Robey
The Notch Regulator Numb Links the Notch and TCR Signaling Pathways
J. Immunol., January 15, 2005; 174(2): 890 - 897.
[Abstract] [Full Text] [PDF]


Home page
Genes Dev.Home page
E. J. Huang, H. Li, A. A. Tang, A. K. Wiggins, R. L. Neve, W. Zhong, L. Y. Jan, and Y. N. Jan
Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization
Genes & Dev., January 1, 2005; 19(1): 138 - 151.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
R. Zhang, Z. Zhang, C. Zhang, L. Zhang, A. Robin, Y. Wang, M. Lu, and M. Chopp
Stroke Transiently Increases Subventricular Zone Cell Division from Asymmetric to Symmetric and Increases Neuronal Differentiation in the Adult Rat
J. Neurosci., June 23, 2004; 24(25): 5810 - 5815.
[Abstract] [Full Text] [PDF]


Home page
Stem CellsHome page
B.M. Deasy, R.J. Jankowski, T.R. Payne, B. Cao, J.P. Goff, J.S. Greenberger, and J. Huard
Modeling Stem Cell Population Growth: Incorporating Terms for Proliferative Heterogeneity
Stem Cells, September 1, 2003; 21(5): 536 - 545.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
D. A. Lyons, A. T. Guy, and J. D. W. Clarke
Monitoring neural progenitor fate through multiple rounds of division in an intact vertebrate brain
Development, August 1, 2003; 130(15): 3427 - 3436.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
M. A. McGill and C. J. McGlade
Mammalian Numb Proteins Promote Notch1 Receptor Ubiquitination and Degradation of the Notch1 Intracellular Domain
J. Biol. Chem., June 13, 2003; 278(25): 23196 - 23203.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
M. Cayouette and M. Raff
The orientation of cell division influences cell-fate choice in the developing mammalian retina
Development, June 1, 2003; 130(11): 2329 - 2339.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
Q. Shen, W. Zhong, Y. N. Jan, and S. Temple
Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts
Development, March 12, 2003; 129(20): 4843 - 4853.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
G. Estivill-Torrus, H. Pearson, V. van Heyningen, D. J. Price, and P. Rashbass
Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors
Development, March 3, 2003; 129(2): 455 - 466.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
F. Yu, X. Morin, R. Kaushik, S. Bahri, X. Yang, and W. Chia
A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts
J. Cell Sci., March 1, 2003; 116(5): 887 - 896.
[Abstract] [Full Text] [PDF]


Home page
Sci SignalHome page
Q. Shen and S. Temple
Creating Asymmetric Cell Divisions by Skewing Endocytosis
Sci. Signal., December 10, 2002; 2002(162): pe52 - pe52.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
A. O. Silva, C. E. Ercole, and S. C. McLoon
Plane of Cell Cleavage and Numb Distribution during Cell Division Relative to Cell Differentiation in the Developing Retina
J. Neurosci., September 1, 2002; 22(17): 7518 - 7525.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Biol.Home page
R. Gallo, F. Zazzeroni, E. Alesse, C. Mincione, U. Borello, P. Buanne, R. D'Eugenio, A. R. Mackay, B. Argenti, R. Gradini, et al.
Ren: a novel, developmentally regulated gene that promotes neural cell differentiation
J. Cell Biol., August 19, 2002; 158(4): 731 - 740.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
R. Roncarati, N. Sestan, M. H. Scheinfeld, B. E. Berechid, P. A. Lopez, O. Meucci, J. C. McGlade, P. Rakic, and L. D'Adamio
The gamma -secretase-generated intracellular domain of beta -amyloid precursor protein binds Numb and inhibits Notch signaling
PNAS, May 14, 2002; 99(10): 7102 - 7107.
[Abstract] [Full Text] [PDF]


Home page
J. Immunol.Home page
M. B. French, U. Koch, R. E. Shaye, M. A. McGill, S. E. Dho, C. J. Guidos, and C. J. McGlade
Transgenic Expression of Numb Inhibits Notch Signaling in Immature Thymocytes But Does Not Alter T Cell Fate Specification
J. Immunol., April 1, 2002; 168(7): 3173 - 3180.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
B. E. Berechid, M. Kitzmann, D. R. Foltz, A. H. Roach, D. Seiffert, L. A. Thompson, R. E. Olson, A. Bernstein, D. B. Donoviel, and J. S. Nye
Identification and Characterization of Presenilin-independent Notch Signaling
J. Biol. Chem., March 1, 2002; 277(10): 8154 - 8165.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
H. Okano, T. Imai, and M. Okabe
Musashi: a translational regulator of cell fate
J. Cell Sci., January 4, 2002; 115(7): 1355 - 1359.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
M. Cayouette, A. V. Whitmore, G. Jeffery, and M. Raff
Asymmetric Segregation of Numb in Retinal Development and the Influence of the Pigmented Epithelium
J. Neurosci., August 1, 2001; 21(15): 5643 - 5651.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
T. Imai, A. Tokunaga, T. Yoshida, M. Hashimoto, K. Mikoshiba, G. Weinmaster, M. Nakafuku, and H. Okano
The Neural RNA-Binding Protein Musashi1 Translationally Regulates Mammalian numb Gene Expression by Interacting with Its mRNA
Mol. Cell. Biol., June 15, 2001; 21(12): 3888 - 3900.
[Abstract] [Full Text]


Home page
Cancer Res.Home page
V. Sriuranpong, M. W. Borges, R. K. Ravi, D. R. Arnold, B. D. Nelkin, S. B. Baylin, and D. W. Ball
Notch Signaling Induces Cell Cycle Arrest in Small Cell Lung Cancer Cells
Cancer Res., April 1, 2001; 61(7): 3200 - 3205.
[Abstract] [Full Text]


Home page
DevelopmentHome page
C. Chambers, Y Peng, H Nguyen, N Gaiano, G Fishell, and J. Nye
Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors
Development, January 3, 2001; 128(5): 689 - 702.
[Abstract] [PDF]


Home page
J. Cell Biol.Home page
E. Santolini, C. Puri, A. E. Salcini, M. C. Gagliani, P. G. Pelicci, C. Tacchetti, and P. P. Di Fiore
Numb Is an Endocytic Protein
J. Cell Biol., December 11, 2000; 151(6): 1345 - 1352.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
W. Zhong, M.-M. Jiang, M. D. Schonemann, J. J. Meneses, R. A. Pedersen, L. Y. Jan, and Y. N. Jan
Mouse numb is an essential gene involved in cortical neurogenesis
PNAS, June 6, 2000; 97(12): 6844 - 6849.
[Abstract] [Full Text] [PDF]


Home page
J. Neurosci.Home page
R. Y. L. Tsai and R. D. G. McKay
Cell Contact Regulates Fate Choice by Cortical Stem Cells
J. Neurosci., May 15, 2000; 20(10): 3725 - 3735.
[Abstract] [Full Text] [PDF]


Home page
J Child NeurolHome page
H. B. Samat and J. H. Menkes
How to Construct a Neural Tube
J Child Neurol, February 1, 2000; 15(2): 110 - 124.
[PDF]


Home page
DevelopmentHome page
Y Wakamatsu, T. Maynard, and J. Weston
Fate determination of neural crest cells by NOTCH-mediated lateral inhibition and asymmetrical cell division during gangliogenesis
Development, January 7, 2000; 127(13): 2811 - 2821.
[Abstract] [PDF]


Home page
J. Biol. Chem.Home page
S. E. Dho, M. B. French, S. A. Woods, and C. J. McGlade
Characterization of Four Mammalian Numb Protein Isoforms. IDENTIFICATION OF CYTOPLASMIC AND MEMBRANE-ASSOCIATED VARIANTS OF THE PHOSPHOTYROSINE BINDING DOMAIN
J. Biol. Chem., November 12, 1999; 274(46): 33097 - 33104.
[Abstract] [Full Text] [PDF]


Home page
ScienceHome page
N. Sestan, S. Artavanis-Tsakonas, and P. Rakic
Contact-Dependent Inhibition of Cortical Neurite Growth Mediated by Notch Signaling
Science, October 22, 1999; 286(5440): 741 - 746.
[Abstract] [Full Text]


Home page
Genes Dev.Home page
N. Hawkins and G. Garriga
Asymmetric cell division: from A to Z
Genes & Dev., December 1, 1998; 12(23): 3625 - 3638.
[Full Text]


Home page
J. Biol. Chem.Home page
S. E. Dho, S. Jacob, C. D. Wolting, M. B. French, L. R. Rohrschneider, and C. J. McGlade
The Mammalian Numb Phosphotyrosine-binding Domain. CHARACTERIZATION OF BINDING SPECIFICITY AND IDENTIFICATION OF A NOVEL PDZ DOMAIN-CONTAINING NUMB BINDING PROTEIN, LNX
J. Biol. Chem., April 10, 1998; 273(15): 9179 - 9187.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
D Levitan and I Greenwald
LIN-12 protein expression and localization during vulval development in C. elegans
Development, January 8, 1998; 125(16): 3101 - 3109.
[Abstract] [PDF]


Home page
Mol. Cell. Biol.Home page
C.-t. Chien, S. Wang, M. Rothenberg, L. Y. Jan, and Y. N. Jan
Numb-Associated Kinase Interacts with the Phosphotyrosine Binding Domain of Numb and Antagonizes the Function of Numb In Vivo
Mol. Cell. Biol., January 1, 1998; 18(1): 598 - 607.
[Abstract] [Full Text]


This Article
Right arrow Summary Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zhong, W.
Right arrow Articles by Jan, Y. N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zhong, W.
Right arrow Articles by Jan, Y. N.