Flk-1 expression defines a population of early embryonic hematopoietic precursors

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[Abstract]<

				R. C. R. Perlingeiro Endoglin is required for hemangioblast and early hematopoietic development Development, August 15, 2007; 134(16): 3041 - 3048. [Abstract] [Full Text] [PDF]

				T. Haremaki, S. T. Fraser, Y.-M. Kuo, M. H. Baron, and D. C. Weinstein Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation PNAS, July 17, 2007; 104(29): 12029 - 12034. [Abstract] [Full Text] [PDF]

				M. Takenaga, M. Fukumoto, and Y. Hori Regulated Nodal signaling promotes differentiation of the definitive endoderm and mesoderm from ES cells J. Cell Sci., June 15, 2007; 120(12): 2078 - 2090. [Abstract] [Full Text] [PDF]

				E. T. ZAMBIDIS, L. SINKA, M. TAVIAN, V. JOKUBAITIS, T. S. PARK, P. SIMMONS, and B. PEAULT Emergence of Human Angiohematopoietic Cells in Normal Development and from Cultured Embryonic Stem Cells Ann. N.Y. Acad. Sci., June 1, 2007; 1106(1): 223 - 232. [Abstract] [Full Text] [PDF]

				H. K. Bone and M. J. Welham Phosphoinositide 3-kinase signalling regulates early development and developmental haemopoiesis J. Cell Sci., May 15, 2007; 120(10): 1752 - 1762. [Abstract] [Full Text] [PDF]

				M. Kennedy, S. L. D'Souza, M. Lynch-Kattman, S. Schwantz, and G. Keller Development of the hemangioblast defines the onset of hematopoiesis in human ES cell differentiation cultures Blood, April 1, 2007; 109(7): 2679 - 2687. [Abstract] [Full Text] [PDF]

				V. Kriz, N. Agren, C. K. Lindholm, S. Lenell, J. Saldeen, J. Mares, and M. Welsh The SHB Adapter Protein Is Required for Normal Maturation of Mesoderm during in Vitro Differentiation of Embryonic Stem Cells J. Biol. Chem., November 10, 2006; 281(45): 34484 - 34491. [Abstract] [Full Text] [PDF]

				C. Rolny, I. Nilsson, P. Magnusson, A. Armulik, L. Jakobsson, P. Wentzel, P. Lindblom, J. Norlin, C. Betsholtz, R. Heuchel, et al. Platelet-derived growth factor receptor-beta promotes early endothelial cell differentiation Blood, September 15, 2006; 108(6): 1877 - 1886. [Abstract] [Full Text] [PDF]

				V. Camara-Clayette, F. Le Pesteur, W. Vainchenker, and F. Sainteny Quantitative Oct4 Overproduction in Mouse Embryonic Stem Cells Results in Prolonged Mesoderm Commitment During Hematopoietic Differentiation In Vitro Stem Cells, August 1, 2006; 24(8): 1937 - 1945. [Abstract] [Full Text] [PDF]

				C. Furuta, H. Ema, S.-i. Takayanagi, T. Ogaeri, D. Okamura, Y. Matsui, and H. Nakauchi Discordant developmental waves of angioblasts and hemangioblasts in the early gastrulating mouse embryo. Development, July 1, 2006; 133(14): 2771 - 2779. [Abstract] [Full Text] [PDF]

				H. Wang, P. C. Charles, Y. Wu, R. Ren, X. Pi, M. Moser, M. Barshishat-Kupper, J. S. Rubin, C. Perou, V. Bautch, et al. Gene Expression Profile Signatures Indicate a Role for Wnt Signaling in Endothelial Commitment From Embryonic Stem Cells Circ. Res., May 26, 2006; 98(10): 1331 - 1339. [Abstract] [Full Text] [PDF]

				H. Priddle, D. R. E. Jones, P. W. Burridge, and R. Patient Hematopoiesis from Human Embryonic Stem Cells: Overcoming the Immune Barrier in Stem Cell Therapies Stem Cells, April 1, 2006; 24(4): 815 - 824. [Abstract] [Full Text] [PDF]

				N. Matsumoto, A. Kubo, H. Liu, K. Akita, F. Laub, F. Ramirez, G. Keller, and S. L. Friedman Developmental regulation of yolk sac hematopoiesis by Kruppel-like factor 6 Blood, February 15, 2006; 107(4): 1357 - 1365. [Abstract] [Full Text] [PDF]

				V. L Bautch Flk1 expression: promiscuity revealed Blood, January 1, 2006; 107(1): 3 - 4. [Full Text] [PDF]

				H. Hirai, I. M Samokhvalov, T. Fujimoto, S. Nishikawa, J. Imanishi, and S.-I. Nishikawa Involvement of Runx1 in the down-regulation of fetal liver kinase-1 expression during transition of endothelial cells to hematopoietic cells Blood, September 15, 2005; 106(6): 1948 - 1955. [Abstract] [Full Text] [PDF]

				G. D. Zheng, K. Hidaka, and T. Morisaki Stable and Uniform Gene Suppression by Site-Specific Integration of siRNA Expression Cassette in Murine Embryonic Stem Cells Stem Cells, September 1, 2005; 23(8): 1028 - 1034. [Abstract] [Full Text] [PDF]

				E. T. Zambidis, B. Peault, T. S. Park, F. Bunz, and C. I. Civin Hematopoietic differentiation of human embryonic stem cells progresses through sequential hematoendothelial, primitive, and definitive stages resembling human yolk sac development Blood, August 1, 2005; 106(3): 860 - 870. [Abstract] [Full Text] [PDF]

				A. Kubo, V. Chen, M. Kennedy, E. Zahradka, G. Q. Daley, and G. Keller The homeobox gene HEX regulates proliferation and differentiation of hemangioblasts and endothelial cells during ES cell differentiation Blood, June 15, 2005; 105(12): 4590 - 4597. [Abstract] [Full Text] [PDF]

				G. Keller Embryonic stem cell differentiation: emergence of a new era in biology and medicine Genes & Dev., May 15, 2005; 19(10): 1129 - 1155. [Abstract] [Full Text] [PDF]

				S. L. D'Souza, A. G. Elefanty, and G. Keller SCL/Tal-1 is essential for hematopoietic commitment of the hemangioblast but not for its development Blood, May 15, 2005; 105(10): 3862 - 3870. [Abstract] [Full Text] [PDF]

				H. Irie, T. Tatsumi, M. Takamiya, K. Zen, T. Takahashi, A. Azuma, K. Tateishi, T. Nomura, H. Hayashi, N. Nakajima, et al. Carbon Dioxide-Rich Water Bathing Enhances Collateral Blood Flow in Ischemic Hindlimb via Mobilization of Endothelial Progenitor Cells and Activation of NO-cGMP System Circulation, March 29, 2005; 111(12): 1523 - 1529. [Abstract] [Full Text] [PDF]

				M. Iida, T. Heike, M. Yoshimoto, S. Baba, H. Doi, and T. Nakahata Identification of cardiac stem cells with FLK1, CD31, and VE-cadherin expression during embryonic stem cell differentiation FASEB J, March 1, 2005; 19(3): 371 - 378. [Abstract] [Full Text] [PDF]

				E. S. Ng, L. Azzola, K. Sourris, L. Robb, E. G. Stanley, and A. G. Elefanty The primitive streak gene Mixl1 is required for efficient haematopoiesis and BMP4-induced ventral mesoderm patterning in differentiating ES cells Development, March 1, 2005; 132(5): 873 - 884. [Abstract] [Full Text] [PDF]

				M. Eguchi, M. Eguchi-Ishimae, A. Green, T. Enver, and M. Greaves Directing oncogenic fusion genes into stem cells via an SCL enhancer PNAS, January 25, 2005; 102(4): 1133 - 1138. [Abstract] [Full Text] [PDF]

				M. M. Dikov, J. E. Ohm, N. Ray, E. E. Tchekneva, J. Burlison, D. Moghanaki, S. Nadaf, and D. P. Carbone Differential Roles of Vascular Endothelial Growth Factor Receptors 1 and 2 in Dendritic Cell Differentiation J. Immunol., January 1, 2005; 174(1): 215 - 222. [Abstract] [Full Text] [PDF]

				M. Tsuneto, A. Tominaga, H. Yamazaki, M. Yoshino, S. H. Orkin, and S.-I. Hayashi Enforced Expression of PU.1 Rescues Osteoclastogenesis from Embryonic Stem Cells Lacking Tal-1 Stem Cells, January 1, 2005; 23(1): 134 - 143. [Abstract] [Full Text] [PDF]

				B. K. Hadland, S. S. Huppert, J. Kanungo, Y. Xue, R. Jiang, T. Gridley, R. A. Conlon, A. M. Cheng, R. Kopan, and G. D. Longmore A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development Blood, November 15, 2004; 104(10): 3097 - 3105. [Abstract] [Full Text] [PDF]

				A. Menthena, N. Deb, M. Oertel, P. N. Grozdanov, J. Sandhu, S. Shah, C. Guha, D. A. Shafritz, and M. D. Dabeva Bone Marrow Progenitors Are Not the Source of Expanding Oval Cells in Injured Liver Stem Cells, November 1, 2004; 22(6): 1049 - 1061. [Abstract] [Full Text] [PDF]

				J. R. Gothert, S. E. Gustin, J. A. M. van Eekelen, U. Schmidt, M. A. Hall, S. M. Jane, A. R. Green, B. Gottgens, D. J. Izon, and C. G. Begley Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium Blood, September 15, 2004; 104(6): 1769 - 1777. [Abstract] [Full Text] [PDF]

				N. Ferrara Vascular Endothelial Growth Factor: Basic Science and Clinical Progress Endocr. Rev., August 1, 2004; 25(4): 581 - 611. [Abstract] [Full Text] [PDF]