A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway

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Altschul, S. F., Gish, W., Miller, W., Meyers, E. W., and Lipman, D (1990). Basic local alignment search tool. J. Mol Biol 215, 403-410.[Medline]

Amo, F. F. d., Smith, D. E., Swiatek, P. J., Gendron-Maguire, M., Greenspan, R. J., McMahon, A. P., and Gridley, T (1992). Expression pattern of Motch , a mouse homolog of Drosophila Notch , suggests an important role in early postimplantation mouse development. Development 115, 737-744.[Abstract]

Artavanis-Tsakonas, S., Matsuno, K., and Fortini, M. E (1995). Notch signaling. Science 268, 225-232.[Abstract/Free Full Text]

Barr, P. J (1991). Mammalian Subtilisins: The long-sought dibasic processing endoproteases. Cell 66, 1-3.[Medline]

Bettenhausen, B., Angelis, M. H. d., Simon, D., Guenet, J.-L., and Gossler, A (1995). Transient and restricted expression during mouse embryogenesis of Dll1 , a murine gene closely related to Drosophila Delta. Development 121, 2407-2418.[Abstract]

Bie, I. D., Savaria, D., Roebroeck, A. J., Day, R., Lazeure, C., Ven, W. J. v. d., and Seidah, N. G (1995). Processing specificity and biosynthesis of the Drosophila melanogaster convertases dfurin1-CRR, dfurin1-X, and dfurin2. J. Biol. Chem 270, 1020-1028.[Abstract/Free Full Text]

Blair, S. S (1993). Mechanism of compartment formation: evidence that non-proliferating cells do not play a critical role in defining the D/V lineage restriction in the developing wing of Drosophila. Development 119, 339-351.[Abstract]

Boone, C., Bussey, H., Greene, D., Thomas, D. Y., and Vernet, T (1986). Yeast killer toxin: site-directed mutations implicate the precursor protein as the immunity component. Cell 46, 105-113.[Medline]

Bradley, R. S., and Brown, A. M. C (1990). The proto-oncogene int - 1 encodes a secreted protein associated with the extracellular matrix. EMBO J 9, 1569-1575.[Medline]

Brand, A., and Perrimon, N (1993). Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415.[Abstract]

Bussey, H (1991). K1 killer toxin, a pore-forming protein from yeast. Molecular Microbiology 5, 2339-2343.[Medline]

Candia, A. F., Hu, H., Crosby, J., Lalley, P. A., Noden, D., Nadeau, J. H., and Wright, C. V. E (1992). Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development 116, 1123-1136.[Abstract]

Cheng, H. J., Nakamoto, M., Bergemann, A. D., and Flanagan, J. G (1995). Complementary gradients in expression and binding of Elf-1 and Mek-4 in development of the topographic retinotectal projection map. Cell 82, 371-381.[Medline]

Chitnis, A., Henrique, D., Lewis, J., Ish-Horowicz, D., and Kintner, C (1995). Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature 375, 761-766.[Medline]

Conlon, R. A., Reaume, A. G., and Rossant, J (1995). Notch1 is required for the coordinate segmentation of somites. Development 121, 1533-1545.[Abstract]

de Celis, J. F.., Garcia-Bellido, A., and Bray, S. J (1996). Activation and function of Notch at the dorsal-ventral boundary of the wing imaginal disc. Development 122, 359-369.[Abstract]

Diaz-Benjumea, F. J., and Cohen, S. M (1995). Serrate signals through Notch to establish a Wingless -dependent organizer at the dorsal/ventral compartment boundary of the Drosophila wing. Development 121, 4215-4225.[Abstract]

Doherty, D., Feger, G., Younger-Shepherd, S., Jan, L. Y., and Jan, Y. N (1996). Delta is a ventral to dorsal signal complementary to Serrate , another Notch ligand, in Drosophila wing formation. Genes Dev 10, 421-434.[Abstract/Free Full Text]

Ellisen, L. W., Bird, J., West, D. C., Soreng, A. L., Reynolds, T. C., Smith, S. D., and Sklar, J (1991). TAN-1 , the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms. Cell 66, 649-661.[Medline]

Fahrner, K., Hogan, B. L. M., and Flavell, R. A (1987). Transcription of the H-2 and Qa genes in embryonic and adult mice. EMBO J 6, 1265-1271.[Medline]

Flanagan, J. G., and Leder, P (1990). The Kit ligand: a cell surface molecule altered in Steel mutant fibroblasts. Cell 63, 185-194.[Medline]

Garcia-Bellido, A (1975). Genetic control of wing disc development in Drosophila. Ciba Foundation Symposium 29, 161-182.

Hinz, U., Giebel, B., and Campos-Ortega, J (1994). The basic-helix-loop-helix domain of Drosophila lethal of scute protein is sufficient for proneural function and activates neurogenic genes. Cell 79, 77-87.

Irvine, K. D., and Wieschaus, E (1994). fringe , a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 79, 595-606.[Medline]

Jessell, T. M., and Melton, D. A (1992). Diffusible factors in vertebrate embryonic induction. Cell 68, 257-270.[Medline]

Keynes, R. J., and Stern, C. D (1988). Mechanisms of vertebrate segmentation. Development 103, 413-430.[Medline]

Kim, J., Irvine, K. D., and Carroll, S. B (1995). Cell recognition, signal induction, and symmetrical gene activation at the dorsal-ventral boundary of the developing Drosophila wing. Cell 82, 795-802.[Medline]

Kim, J., Sebring, A., Esch, J. J., Kraus, M. E., Vorwerk, K., Magee, J., and Carroll, S. B (1996). Integration of positional signals and regulation of wing formation and identity by Drosophila vestigial gene. Nature 382, 133-138.[Medline]

Lawrence, P. A., and Struhl, G (1996). Morphogens, compartments, and pattern: Lessons from Drosophila. Cell 85, 951-961.[Medline]

Lee, J. J., Ekker, S. C., Kessler, D. P. v., Porter, J. A., Sun, B. I., and Beachy, P. A (1994). Autoproteolysis in hedgehog protein biogenesis. Science 266, 1528-1537.[Abstract/Free Full Text]

Lewis, J (1996). Neurogenic genes and vertebrate neurogenesis. Curr. Opin. Neurobiol 6, 3-10.[Medline]

Lindsell, C. E., Shawber, C. J., Boulter, J., and Weinmaster, G (1995). Jagged : a mammalian ligand that activates Notch1. Cell 80, 909-917.[Medline]

Lumsden, A. and Krumlauf, R (1996). Patterning the vertebrate neuraxis. Science 274, 1109-1115.[Abstract/Free Full Text]

Morisato, D. and Anderson, K.V (1995). Signaling pathways that establish the dorsal-ventral pattern of the Drosophila embryo. Ann. Rev. Genet 29, 371-399.[Medline]

Nieto, M. A., Gilardi-Hebenstreit, P., Charnay, P., and Wilkinson, D. G (1992). A receptor protein tyrosine kinase implicated in the segmental patterning of the hindbrain and mesoderm. Development 116, 1137-1150.[Abstract]

Riddle, R. D., Johnson, R. L., Laufer, E., and Tabin, C (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.[Medline]

Roebroek, A. J., Ayoubi, T. A., Creemers, J. W., Pauli, I. G., and Ven, W. v. d (1995). The Dfur2 gene of Drosophilamelanogaster: Genetic organization, expression during embryogenesis, and pro-protein processing activity of its translational product Dfurin2. DNA and Cell Biology 14, 223-234.[Medline]

Rubin, G. M., and Spradling, A. C (1982). Genetic transformation of Drosophila with transposable element vectors. Science 218, 348-353.[Abstract/Free Full Text]

Rulifson, E.J. and Blair, S.S (1995). Notch regulates wingless expression and is not required for reception of the paracrine wingless signal during wing neurogenesis in Drosophila. Development 121, 2813-2824.[Abstract]

Speicher, S.A., Thomas, U., Hinz, U., and Knust, E (1994). The Serrate locus of Drosophila and its role in morphogenesis of the wing imaginal discs: control of cell proliferation. Development 120, 535-544.[Abstract]

Tam, P. P. L., and Trainor, P. A (1994). Specification and segmentation of the paraxial mesoderm. Anat. Embryol 189, 275-305.[Medline]

Tanabe, Y. and Jessell, T. M (1996). Diversity and pattern in the developing spinal cord. Science 274, 1115-1123.[Abstract/Free Full Text]

Thomsen, G. H., and Melton, D. A (1993). Processed Vg1 protein is an axial mesoderm inducer in Xenopus. Cell 74, 433-441.[Medline]

van den Heuvel, M., Nusse, R., Johnston, P., and Lawrence, P.A (1989). Distribution of the wingless gene product in Drosophila embryos: A protein involved in cell-cell communication. Cell 59, 739-749.[Medline]

Wu, J. Y., Wen, L., Zhang, W.-J., and Rao, Y (1996). The secreted product of Xenopus gene lunatic Fringe , a vertebrate signaling molecule. Science 273, 355-358.[Abstract]

Zecca, M., Basler, K., and Struhl, G (1996). Direct and long-range action of a wingless morphogen gradient. Cell 87, 833-844.[Medline]

Zettlmeissl, G., Gregersen, J.-P., Duport, J. M., Mehdi, S., Reiner, G., and Seed, B (1990). Expression and characterization of human CD4: Immunoglobulin fusion proteins. DNA and Cell Biology 9, 347-353.[Medline]

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				E. T. Shifley, K. M. VanHorn, A. Perez-Balaguer, J. D. Franklin, M. Weinstein, and S. E. Cole Oscillatory lunatic fringe activity is crucial for segmentation of the anterior but not posterior skeleton Development, March 1, 2008; 135(5): 899 - 908. [Abstract] [Full Text] [PDF]

				S.-i. Tsukumo, K. Hirose, Y. Maekawa, K. Kishihara, and K. Yasutomo Lunatic Fringe Controls T Cell Differentiation through Modulating Notch Signaling J. Immunol., December 15, 2006; 177(12): 8365 - 8371. [Abstract] [Full Text] [PDF]

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				K. L. Hahn, J. Johnson, B. J. Beres, S. Howard, and J. Wilson-Rawls Lunatic fringe null female mice are infertile due to defects in meiotic maturation Development, February 15, 2005; 132(4): 817 - 828. [Abstract] [Full Text] [PDF]

				L.-T. Yang, J. T. Nichols, C. Yao, J. O. Manilay, E. A. Robey, and G. Weinmaster Fringe Glycosyltransferases Differentially Modulate Notch1 Proteolysis Induced by Delta1 and Jagged1 Mol. Biol. Cell, February 1, 2005; 16(2): 927 - 942. [Abstract] [Full Text] [PDF]

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				T. Okajima, A. Xu, and K. D. Irvine Modulation of Notch-Ligand Binding by Protein O-Fucosyltransferase 1 and Fringe J. Biol. Chem., October 24, 2003; 278(43): 42340 - 42345. [Abstract] [Full Text] [PDF]

				T. Correia, V. Papayannopoulos, V. Panin, P. Woronoff, J. Jiang, T. F. Vogt, and K. D. Irvine Molecular genetic analysis of the glycosyltransferase Fringe in Drosophila PNAS, May 27, 2003; 100(11): 6404 - 6409. [Abstract] [Full Text] [PDF]

				S. Shi and P. Stanley Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways PNAS, April 29, 2003; 100(9): 5234 - 5239. [Abstract] [Full Text] [PDF]

				A. Nomura-Kitabayashi, Y. Takahashi, S. Kitajima, T. Inoue, H. Takeda, and Y. Saga Hypomorphic Mesp allele distinguishes establishment of rostrocaudal polarity and segment border formation in somitogenesis Development, March 7, 2003; 129(10): 2473 - 2481. [Abstract] [Full Text] [PDF]

				L. Shao, D. J. Moloney, and R. Haltiwanger Fringe Modifies O-Fucose on Mouse Notch1 at Epidermal Growth Factor-like Repeats within the Ligand-binding Site and the Abruptex Region J. Biol. Chem., February 28, 2003; 278(10): 7775 - 7782. [Abstract] [Full Text] [PDF]

				G. K. H. Przemeck, U. Heinzmann, J. Beckers, and M. Hrabe de Angelis Node and midline defects are associated with left-right development in Delta1 mutant embryos Development, January 1, 2003; 130(1): 3 - 13. [Abstract] [Full Text] [PDF]

				S.-E. Lin, T. Oyama, T. Nagase, K. Harigaya, and M. Kitagawa Identification of New Human Mastermind Proteins Defines a Family That Consists of Positive Regulators for Notch Signaling J. Biol. Chem., December 20, 2002; 277(52): 50612 - 50620. [Abstract] [Full Text] [PDF]

				V. M. Panin, L. Shao, L. Lei, D. J. Moloney, K. D. Irvine, and R. S. Haltiwanger Notch Ligands Are Substrates for Protein O-Fucosyltransferase-1 and Fringe J. Biol. Chem., August 9, 2002; 277(33): 29945 - 29952. [Abstract] [Full Text] [PDF]

				S. S. Nijjar, L. Wallace, H. A. Crosby, S. G. Hubscher, and A. J. Strain Altered Notch Ligand Expression in Human Liver Disease : Further Evidence for a Role of the Notch Signaling Pathway in Hepatic Neovascularization and Biliary Ductular Defects Am. J. Pathol., May 1, 2002; 160(5): 1695 - 1703. [Abstract] [Full Text] [PDF]

				S. L. Dunwoodie, M. Clements, D. B. Sparrow, X. Sa, R. A. Conlon, and R. S. P. Beddington Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm Development, January 4, 2002; 129(7): 1795 - 1806. [Abstract] [Full Text] [PDF]

				J. Chen, D. J. Moloney, and P. Stanley Fringe modulation of Jagged1-induced Notch signaling requires the action of beta 4galactosyltransferase-1 PNAS, November 9, 2001; (2001) 241398098. [Abstract] [Full Text] [PDF]

				L. T. Ziemer, D. Pennica, and A. J. Levine Identification of a Mouse Homolog of the Human BTEB2 Transcription Factor as a {beta}-Catenin-Independent Wnt-1-Responsive Gene Mol. Cell. Biol., January 15, 2001; 21(2): 562 - 574. [Abstract] [Full Text]

				A. C.-K. Chung, D. Katz, F. A. Pereira, K. J. Jackson, F. J. DeMayo, A. J. Cooney, and B. W. O'Malley Loss of Orphan Receptor Germ Cell Nuclear Factor Function Results in Ectopic Development of the Tail Bud and a Novel Posterior Truncation Mol. Cell. Biol., January 15, 2001; 21(2): 663 - 677. [Abstract] [Full Text]

				D. J. Moloney, L. H. Shair, F. M. Lu, J. Xia, R. Locke, K. L. Matta, and R. S. Haltiwanger Mammalian Notch1 Is Modified with Two Unusual Forms of O-Linked Glycosylation Found on Epidermal Growth Factor-like Modules J. Biol. Chem., March 24, 2000; 275(13): 9604 - 9611. [Abstract] [Full Text] [PDF]

				M Milan and S. Cohen Temporal regulation of apterous activity during development of the Drosophila wing Development, January 7, 2000; 127(14): 3069 - 3078. [Abstract] [PDF]

				E. de Alava and W. L. Gerald Molecular Biology of the Ewing�s Sarcoma/Primitive Neuroectodermal Tumor Family J. Clin. Oncol., January 5, 2000; 18(1): 204 - 204. [Abstract] [Full Text] [PDF]

				C Jouve, I Palmeirim, D Henrique, J Beckers, A Gossler, D Ish-Horowicz, and O Pourquie Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm Development, January 4, 2000; 127(7): 1421 - 1429. [Abstract] [PDF]

				H. Harada, P. Kettunen, H.-S. Jung, T. Mustonen, Y. A. Wang, and I. Thesleff Localization of Putative Stem Cells in Dental Epithelium and Their Association with Notch and FGF Signaling J. Cell Biol., October 4, 1999; 147(1): 105 - 120. [Abstract] [Full Text] [PDF]

				C. S. Wesley Notch and Wingless Regulate Expression of Cuticle Patterning Genes Mol. Cell. Biol., August 1, 1999; 19(8): 5743 - 5758. [Abstract] [Full Text] [PDF]

				Y. Lee, G. Huang, R. Cameron, G Graham, E. Davidson, L Hood, and R. Britten EST analysis of gene expression in early cleavage-stage sea urchin embryos Development, January 9, 1999; 126(17): 3857 - 3867. [Abstract] [PDF]

				T. Yamaguchi, A Bradley, A. McMahon, and S Jones A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo Development, January 3, 1999; 126(6): 1211 - 1223. [Abstract] [PDF]