Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus

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Aono, A., Hazama, M., Notoya, K., Taketomi, S., Yamasaki, H., Tsukuda, R., Sasaki, S. and Fujisawa, Y (1995). Potent ectopic bone-inducing activity of bone morphogenetic protein 4/7 heterodimer. Biochem. Biophy. Res. Commun 210, 679-677.

Arendt, D. and Nubler-Jung, K (1994). Inversion of dorsoventral axis?. Nature 371, 26-.[Medline]

Cho, K. W., Morita, E. A., Wright, C. V. and De Robertis, E. M (1991). Overexpression of a homeodomain protein confers axis-forming activity to uncommitted Xenopus embryonic cells. Cell 65, 55-64.[Medline]

Christian, J.L. and Moon, R.T (1993). Interactions between Xwnt-8 and Spemann organizer signalling pathways generate dorso-ventral pattern in the embryonic mesoderm of Xenopus. Genes Dev 7, 13-28.[Abstract/Free Full Text]

Clement, J. H., Fettes, P., Kn\232chel, S., Lef, J. and Kn\232chel, W (1995). Bone morphogenetic protein 2 in the early development of Xenopus laevis. Mech. Dev 52, 357-370.[Medline]

Dale, L. and Slack, J. M (1987). Fate map for the 32-cell stage of Xenopus laevis. Development 99, 527-51.[Abstract/Free Full Text]

Dale, L., Howes, G., Price, B. M. and Smith, J. C (1992). Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development. Development 115, 573-85.[Abstract]

De Robertis, E. M. and Sasai, Y (1996). A common plan for dorsoventral patterning in Bilateria. Nature 380, 37-40.[Medline]

Fainsod, A., Steinbeisser, H. and De Robertis, E. M (1994). On the function of Bmp-4 in patterning the marginal zone of the Xenopus embryo. EMBO J 13, 5015-25.[Medline]

Ferguson, E. L. and Anderson, K. V (1992). Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461.[Medline]

Ferguson, E. L (1996). Conservation of dorsal-ventral patterning in arthropods and chordates. Current Opin. Genet. Dev 6, 424-431.[Medline]

Francois, V. and Bier, E (1995). Xenopus chordin and Drosophila short gastrulation genes encode homologous proteins functioning in dorsal-ventral axis formation. Cell 80, 19-20.[Medline]

Francois, V., Solloway, M., O'Neill, J. W., Emery, J. and Bier, E (1994). Dorsal-ventral patterning of the Drosophila embryo depends on a putative negative growth factor encoded by the short gastrulation gene. Genes Dev 8, 2602-16.[Abstract/Free Full Text]

Frank, D. and Harland, R. M (1991). Transient expression of XMyoD in non-somitic mesoderm of Xenopus gastrulae. Development 113, 1387-93.[Abstract]

Gawantka, V., Delius, H., Hirschfeld, K., Blumenstock, C. and Niehrs, C (1995). Antagonizing the Spemann organizer: role of the homeobox gene Xvent-1. EMBO J 14, 6268-79.[Medline]

Graff, J. M., Thies, R. S., Song, J. J., Celeste, A. J. and Melton, D. A (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-79.[Medline]

Graff, J. M., Bansal, A. and Melton, D. A (1996). Xenopus Mad proteins transduce distinct subsets of signals for the TGF-superfamily. Cell 85, 479-487.[Medline]

Green, J. B. A. and Smith, J. C (1990). Graded changes in dose of a Xenopus activin A homologue elicit stepwise transitions in embryonic cell fate. Nature 347, 391-394.[Medline]

Green, J. B. A., New, H. V. and Smith, J. C (1992). Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 71, 731-739.[Medline]

Gurdon, J. B., Harger, P., Mitchell, A. and Lemaire, P (1994). Activin signaling and response to a morphogen gradient. Nature 371, 487-492.[Medline]

Harland, R. M (1991). In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol 36, 685-95.[Medline]

Harland, R. M (1994). The transforming growth factor beta family and induction of the vertebrate mesoderm: bone morphogenetic proteins are ventral inducers [comment]. Proc. Natl. Acad. Sci. USA 91, 10243-6.[Free Full Text]

Hawley, S. H., Wunnenberg, S. K., Hashimoto, C., Laurent, M. N., Watabe, T., Blumberg, B. W. and Cho, K. W (1995). Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. Genes Dev 9, 2923-35.[Abstract/Free Full Text]

Hemmati-Brivanlou, A., Kelly, O. G. and Melton, D. A (1994). Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-95.[Medline]

Hemmati-Brivanlou, A. and Thomsen, G. H (1995). Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and Bmp-4. Dev. Genet 17, 78-89.[Medline]

Hogan, B. M (1996). Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10, 1580-1594.[Free Full Text]

Holley, S. A., Jackson, P. D., Sasai, Y., Lu, B., De Robertis, E. M.,Hoffmann, M. and Ferguson, E. L (1995). A conserved system for dorso-ventral patterning in insects and vertebrates involving sog and chordin. Nature 376, 249-253.[Medline]

Holley, S. A., Neul, J. L., Attisano, L., O'Connor, M. B., De Robertis, E. M. and Ferguson, E. L (1996). The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing dpp from activating its receptor. Cell 86, 607-617.[Medline]

Hoodless, P., Haerry, T., Abdollah, S., Stapleton, M., O'Connor, M. B., Attisano, L. and Wrana, J (1996). MADR1, a Mad-related protein that functions in BMP-2 signaling pathways. Cell 85, 489-500.[Medline]

Hopwood, N. D., Pluck, A. and Gurdon, J. B (1991). Xenopus Myf-5 marks early muscle cells and can activate muscle genes ectopically in early embryos. Development 111, 551-560.[Abstract]

Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. and Hogan, B. L (1992). DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-47.[Abstract]

Jones, C. M. and Smith, J. C (1995). Revolving vertebrates. Curr. Biol 5, 574-576.[Medline]

Jones, C. M., Kuehn, M. R., Hogan, B. L., Smith, J. C. and Wright, C. V (1995). Nodal-related signals induce axial mesoderm and dorsalize mesoderm during gastrulation. Development 121, 3651-62.[Abstract]

Jones, C. M., Dale, L., Hogan, B. L. M., Wright, C. V. E. and Smith, J. C (1996). Bone morphogenetic protein-4 (Bmp-4) acts during gastrula stages to cause ventralization of Xenopus embryos. Development 122, 1545-1554.[Abstract]

Jones, C. M., Armes, N. and Smith, J.C (1996). Signalling by TGF-b family members: short range effects of Xnr2 and Bmp-4 contrast with the long-range effects of activin. Curr. Biol 6, 1468-1475.[Medline]

Kessler, D. S. and Melton, D. A (1995). Induction of dorsal mesoderm by soluble, mature Vg1 protein. Development 121, 2155-2164.[Abstract]

K\232ster, M., Plessow, S., Clement, J. H., Lorenz, A., Tiedemann, H. and Kn\232chel, W (1991). Bone morphogenetic protein 4 (Bmp-4), a member of the TGF-beta family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity. Mech. Dev 33, 191-9.[Medline]

Ladher, R., Mohun, T. J., Smith, J. C. and Snape, A. M (1996). Xom : a Xenopus homeobox gene that mediates the early effects of Bmp-4. Development 122, 2385-2394.[Abstract]

Lamb, T. M., Knecht, A. K., Smith, W. C., Stachel, S. E., Economides, A. N., Stahl, N., Yancopolous, G. D. and Harland, R. M (1993). Neural induction by the secreted polypeptide noggin. Science 262, 713-8.[Abstract/Free Full Text]

Lecuit, T., Brook, W. J., Ng, M., Calleja, M., Sun, H. and Cohen, S (1996). Two distinct mechanisms for long-range patterning by decapentaplegic in the Drosophila wing. Nature 381, 387-392.[Medline]

Lemaire, P., Garett, N. and Gurdon, J. B (1995). Expression cloning of Siamois, a Xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis. Cell 81, 85-94.[Medline]

Liem, K. F., Tremml, G., Roelink, H. and Jessell, T. M (1995). Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell 82, 969-979.[Medline]

Liu, F., Baker, J., Doody, J., Carcamo, J. and Massague, J (1996). A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620-623.[Medline]

Maeno, M., Ong, R. C., Suzuki, A., Ueno, N. and Kung, H. F (1994). A truncated bone morphogenetic protein 4 receptor alters the fate of ventral mesoderm to dorsal mesoderm: roles of animal pole tissue in the development of ventral mesoderm. Proc. Natl. Acad. Sci. USA 91, 10260-4.[Abstract/Free Full Text]

Matzuk, M. M., Kumar, T. R., Vassalli, A., Bickenbach, J. R., Roop, D. R., Jaenisch, R. and Bradley, A (1995). Functional analysis of activins during mammalian development. Nature 374, 354-356.[Medline]

Moos, M., Wang, S. and Krinks, M (1995). Anti-dorsalizing morphogenetic protein is a novel TGF-beta homolog expressed in the Spemann organizer. Development 121, 4293-4301.[Abstract]

Nellen, D., Burke, R., Struhl, G. and Basler, K (1996). Direct and long-range action of a dpp morphogen gradient. Cell 85, 357-368.[Medline]

Niehrs, C. and De Robertis, E. M (1991). Ectopic expression of a homeobox gene changes cell fate in Xenopus embryos in a position-specific manner. EMBO J 10, 3621-9.[Medline]

Niehrs, C., Steinbeisser, H. and De Robertis, E. M (1994). Mesodermal patterning by a gradient of the vertebrate homeobox gene goosecoid. Science 263, 817-20.[Abstract/Free Full Text]

Niehrs, C (1996). Mad connection to the nucleus. Nature 381, 561-562.[Medline]

Nishimatsu, S., Suzuki, A., Shoda, A., Murakami, K. and Ueno, N (1992). Genes for bone morphogenetic proteins are differentially transcribed in early amphibian embryos. Biochem. Biophys. Res. Commun 186, 1487-95.[Medline]

Nishimatsu, S., Takebayashi, K., Suzuki, A., Murakami, K. and Ueno, N (1993). Immunodetection of Xenopus bone morphogenetic protein-4 in early embryos. Growth Factors 8, 173-6.[Medline]

Onichtchouk, D., Gawantka, V., Dosch, R., Delius, H., Hirschfeld, K., Blumenstock, C. and Niehrs, C (1996). The Xvent-2 homeobox gene is part of the Bmp-4 signaling pathway controlling dorsoventral patterning of Xenopus mesoderm. Development 122, 3045-3053.[Abstract]

Papalopulu, N. and Kintner, C (1996). A Xenopus gene, Xbr-1, defines a novel class of homeobox genes and is expressed in the dorsal ciliary margin of the eye. Dev. Biol 174, 104-114.[Medline]

Piccolo, S., Sasai, Y., Lu, B. and DeRobertis, E. M (1996). Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to Bmp-4. Cell 86, 589-598.[Medline]

Reem-Kalma, Y., Lamb, T. and Frank, D (1995). Competition between noggin and Bmp-4 activities may regulate dorsalization during Xenopus development. Proc. Natl. Acad. Sci. USA 92, 12141-12145.[Abstract/Free Full Text]

Reilly, K. M. and Melton, D. A (1996). Short-range signaling by candidate morphogens of the TGF-beta family and evidence for a relay mechanism of induction. Cell 86, 743-754.[Medline]

Rupp, R. A., Snider, L. and Weintraub, H (1994). Xenopus embryos regulate the nuclear localization of XMyoD. Genes Dev 8, 1311-23.[Abstract/Free Full Text]

Ruiz i Altaba, A. and Jessel, T (1991). Retinoic acid modifies mesodermal patterning in early Xenopus embryos. Genes Dev 5, 175-87.[Abstract/Free Full Text]

Sanes, J. R., Rubenstein, J. L. and Nicolas, J. F (1986). Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos. EMBO J 5, 3133-42.[Medline]

Sasai, Y., Lu, B., Steinbeisser, H., Geissert, D., Gont, L. K. and De Robertis, E. M (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-90.[Medline]

Sasai, Y., Lu, B., Steinbeisser, H. and De Robertis, E. M (1995). Regulation of neural induction by the chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.[Medline]

Schmidt, J., Francois, V., Bier, E. and Kimelman, D (1995). Drosophila short gastrulation induces an ectopic axis in Xenopus : evidence for conserved mechanisms of dorsal-ventral patterning. Development 121, 4319-4328.[Abstract]

Schmidt, J. E., Suzuki, A., Ueno, N. and Kimelman, D (1995). Localized Bmp-4 mediates dorsal/ventral patterning in the early Xenopus embryo. Dev. Biol 169, 37-50.[Medline]

Schmidt, J. E., von Dassow, G. and Kimelman, D (1996). Regulation of dorsal-ventral patterning: the ventralizing effects of the novel Xenopus homeobox gene Vox. Development 122, 1711-1721.[Abstract]

Schulte-Merker, S., Smith, J. C. and Dale, L (1994). Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction?. EMBO J 15, 3533-3541.

Sekelsky, J. J., Newfeld, S. J., Raftery, L. A., Chartoff, E. H. and Gelbart, W. M (1995). Genetic characterisation and cloning of Mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358.[Abstract]

Shoda, A., Murakami, K. and Ueno, N (1994). Biologically active BMP-2 in early Xenopus laevis embryos. Biochem Biophys Res Commun 198, 1267-74.[Medline]

Slack, J. M. W (1994). Inducing factors in Xenopus early embryos. Curr. Biol 4, 116-127.[Medline]

Smith, J. C. and Slack, J. M (1983). Dorsalization and neural induction: properties of the organizer in Xenopus laevis. J. Embryol. Exp. Morph 78, 299-317.[Medline]

Smith, W. C. and Harland, R. M (1992). Expression cloning of noggin, a newdorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70, 829-40.[Medline]

Smith, W. C., Knecht, A. K., Wu, M. and Harland, R. M (1993). Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature 361, 547-9.[Medline]

Smith, W. C., McKendry, R., Ribisi, S. J. and Harland, R. M (1995). A nodal-related gene defines a physical and functional domain within the Spemann organizer. Cell 82, 37-46.[Medline]

Steinbeisser, H., Fainsod, A., Niehrs, C., Sasai, Y. and DeRobertis, E. M (1995). The role of gsc and Bmp-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss of function study using antisense RNA. EMBO J 14, 5230-5243.[Medline]

Steward, R. M. and Gerhard, J. C (1990). The anterior extend of dorsal development depends on the quantity of organizer in the late blastula. Development 109, 363-372.[Abstract]

Suzuki, A., Nishimatsu, S., Shoda, A., Takebayashi, K., Murakami, K. and Ueno, N (1993). Biochemical properties of amphibian bone morphogenetic protein-4 expressed in CHO cells. Biochem. J 291, 413-417.

Suzuki, A., Thies, R. S., Yamaji, N., Song, J. J., Wozney, J. M., Murakami, K. and Ueno, N (1994). A truncated bone morphogenetic protein receptor affects dorsal-ventral patterning in the early Xenopus embryo. Proc. Natl. Acad. Sci. USA 91, 10255-9.[Abstract/Free Full Text]

Thomsen, G. H (1996). Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor. Development 122, 2359-2366.[Abstract]

Tidman-Ault, C., Dirksen, M. L. and Jamrich, M (1996). A novel homeobox gene PV.1 mediates induction of ventral mesoderm in Xenopus embryos. Proc. Natl. Acad. Sci. USA 93, 6415-6420.[Abstract/Free Full Text]

Vassalli, A., Matzuk, M. M., Gardner, H. A., Lee, K. F. and Jaenisch, R (1994). Activin/inhibin beta B subunit gene disruption leads to defects in eyelid development and female reproduction. Genes Dev 8, 414-427.[Abstract/Free Full Text]

Wharton, K. A., Ray, R. P. and Gelbart, W. M (1993). An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development 117, 807-822.[Abstract]

Wilson, P. A. and Hemmati-Brivanlou, A (1995). Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376, 331-333.[Medline]

Winnier, G., Blessing, M., Labosky, P. A. and Hogan, B. L. M (1995). Bone morphogenetic protein 4 is required for mesoderm formation and patterning in the mouse. Genes Dev 9, 2105-2116.[Abstract/Free Full Text]

Yamashita, H., Dijke, P., Huylebroeck, D., Sampath, T. K. andries, M., Smith, J. C., Heldin, C. H. and Miyazono, K (1995). Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects. J. Cell Biol 130, 217-226.[Abstract/Free Full Text]

Zimmerman, L. B., De Jes\234s-Escobar, J.-E. and Harland, R. M (1996). The Spemann organizer Signal noggin binds and inactivates bone morphogenetic protein-4. Cell 86, 599-606.[Medline]

Zon, L. I (1995). Developmental biology of hematopoiesis. Blood_Fb_86 , 2876-2891.A graded response to Bmp-4 has recently been observed in zebrafish (Neave, B., Holder, N. and Patient, N., 1997). A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish. Mech. Dev 62, 183-195.

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Development, January 12, 1999; 126(23): 5327 - 5337.
[Abstract] [PDF]

D Sela-Donenfeld and C Kalcheim
Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube
Development, January 11, 1999; 126(21): 4749 - 4762.
[Abstract] [PDF]

K. Barth, Y Kishimoto, K. Rohr, C Seydler, S Schulte-Merker, and S. Wilson
Bmp activity establishes a gradient of positional information throughout the entire neural plate
Development, January 11, 1999; 126(22): 4977 - 4987.
[Abstract] [PDF]

S. Connors, J Trout, M Ekker, and M. Mullins
The role of tolloid/mini fin in dorsoventral pattern formation of the zebrafish embryo
Development, January 6, 1999; 126(14): 3119 - 3130.
[Abstract] [PDF]

M Hild, A Dick, G. Rauch, A Meier, T Bouwmeester, P Haffter, and M Hammerschmidt
The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo
Development, January 5, 1999; 126(10): 2149 - 2159.
[Abstract] [PDF]

M Nikaido, M Tada, H Takeda, A Kuroiwa, and N Ueno
In vivo analysis using variants of zebrafish BMPR-IA: range of action and involvement of BMP in ectoderm patterning
Development, January 1, 1999; 126(1): 181 - 190.
[Abstract] [PDF]

D.-Y. Wu, G. E. Schneider, J. Silver, M. Poston, and S. Jhaveri
A Role for Tectal Midline Glia in the Unilateral Containment of Retinocollicular Axons
J. Neurosci., October 15, 1998; 18(20): 8344 - 8355.
[Abstract] [Full Text] [PDF]

R. Reshef, M. Maroto, and A. B. Lassar
Regulation of dorsal somitic cell fates: BMPs and Noggin control the timing and pattern of myogenic regulator�expression
Genes & Dev., February 1, 1998; 12(3): 290 - 303.
[Abstract] [Full Text]

T. Sykes, A. Rodaway, M. Walmsley, and R. Patient
Suppression of GATA factor activity causes axis duplication in Xenopus
Development, January 12, 1998; 125(23): 4595 - 4605.
[Abstract] [PDF]

S Noramly and B. Morgan
BMPs mediate lateral inhibition at successive stages in feather tract development
Development, January 10, 1998; 125(19): 3775 - 3787.
[Abstract] [PDF]

J. Hudson, S. Podos, K Keith, S. Simpson, and E. Ferguson
The Drosophila Medea gene is required downstream of dpp and encodes a functional homolog of human Smad4
Development, January 4, 1998; 125(8): 1407 - 1420.
[Abstract] [PDF]

D Onichtchouk, A Glinka, and C Niehrs
Requirement for Xvent-1 and Xvent-2 gene function in dorsoventral patterning of Xenopus mesoderm
Development, January 4, 1998; 125(8): 1447 - 1456.
[Abstract] [PDF]

J Heasman
Patterning the Xenopus blastula
Development, January 11, 1997; 124(21): 4179 - 4191.
[Abstract] [PDF]

E Hirsinger, D Duprez, C Jouve, P Malapert, J Cooke, and O Pourquie
Noggin acts downstream of Wnt and Sonic Hedgehog to antagonize BMP4 in avian somite patterning
Development, January 11, 1997; 124(22): 4605 - 4614.
[Abstract] [PDF]

K. A. Henningfeld, H. Friedle, S. Rastegar, and W. Knochel
Autoregulation of Xvent-2B; Direct Interaction and Functional Cooperation of Xvent-2 and Smad1
J. Biol. Chem., January 11, 2002; 277(3): 2097 - 2103.
[Abstract] [Full Text] [PDF]

S. Paine-Saunders, B. L. Viviano, A. N. Economides, and S. Saunders
Heparan Sulfate Proteoglycans Retain Noggin at the Cell Surface. A POTENTIAL MECHANISM FOR SHAPING BONE MORPHOGENETIC PROTEIN GRADIENTS
J. Biol. Chem., January 11, 2002; 277(3): 2089 - 2096.
[Abstract] [Full Text] [PDF]

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				K. Mintzer, M. Lee, G Runke, J Trout, M Whitman, and M. Mullins Lost-a-fin encodes a type I BMP receptor, Alk8, acting maternally and zygotically in dorsoventral pattern formation Development, January 3, 2001; 128(6): 859 - 869. [Abstract] [PDF]

				G Drossopoulou, K. Lewis, J. Sanz-Ezquerro, N Nikbakht, A. McMahon, C Hofmann, and C Tickle A model for anteroposterior patterning of the vertebrate limb based on sequential long- and short-range Shh signalling and Bmp signalling Development, January 4, 2000; 127(7): 1337 - 1348. [Abstract] [PDF]

				T Narita, K Saitoh, T Kameda, A Kuroiwa, M Mizutani, C Koike, H Iba, and S Yasugi BMPs are necessary for stomach gland formation in the chicken embryo: a study using virally induced BMP-2 and Noggin expression Development, January 3, 2000; 127(5): 981 - 988. [Abstract] [PDF]

				L. Angerer, D. Oleksyn, C. Logan, D. McClay, L Dale, and R. Angerer A BMP pathway regulates cell fate allocation along the sea urchin animal-vegetal embryonic axis Development, January 3, 2000; 127(5): 1105 - 1114. [Abstract] [PDF]

				V. Nguyen, J Trout, S. Connors, P Andermann, E Weinberg, and M. Mullins Dorsal and intermediate neuronal cell types of the spinal cord are established by a BMP signaling pathway Development, January 3, 2000; 127(6): 1209 - 1220. [Abstract] [PDF]

				M. Roudbaraki, A. Lorsignol, L. Langouche, G. Callewaert, H. Vankelecom, and C. Denef Target Cells of {gamma}3-Melanocyte-Stimulating Hormone Detected through Intracellular Ca2+ Responses in Immature Rat Pituitary Constitute a Fraction of All Main Pituitary Cell Types, but Mostly Express Multiple Hormone Phenotypes at the Messenger Ribonucleic Acid Level. Refractoriness to Melanocortin-3 Receptor Blockade in the Lacto-Somatotroph Lineage Endocrinology, October 1, 1999; 140(10): 4874 - 4885. [Abstract] [Full Text]

				A. Pavlova, R. O. Stuart, M. Pohl, and S. K. Nigam Evolution of gene expression patterns in a model of branching morphogenesis Am J Physiol Renal Physiol, October 1, 1999; 277(4): F650 - F663. [Abstract] [Full Text] [PDF]

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