Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling

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				P. M. Smallwood, J. Williams, Q. Xu, D. J. Leahy, and J. Nathans Mutational Analysis of Norrin-Frizzled4 Recognition J. Biol. Chem., February 9, 2007; 282(6): 4057 - 4068. [Abstract] [Full Text] [PDF]

				X. Zhu, J. Sen, L. Stevens, J. S. Goltz, and D. Stein Drosophila Pipe protein activity in the ovary and the embryonic salivary gland does not require heparan sulfate glycosaminoglycans Development, September 1, 2005; 132(17): 3813 - 3822. [Abstract] [Full Text] [PDF]

				J. Vatsyayan, H.-L. Peng, and H.-Y. Chang Analysis of Human UDP-Glucose Dehydrogenase Gene Promoter: Identification of an Sp1 Binding Site Crucial for the Expression of the Large Transcript J. Biochem., June 1, 2005; 137(6): 703 - 709. [Abstract] [Full Text] [PDF]

				K. Weber, N. Johnson, D. Champlin, and A. Patty Many P-Element Insertions Affect Wing Shape in Drosophila melanogaster Genetics, March 1, 2005; 169(3): 1461 - 1475. [Abstract] [Full Text] [PDF]

				X. Franch-Marro, O. Marchand, E. Piddini, S. Ricardo, C. Alexandre, and J.-P. Vincent Glypicans shunt the Wingless signal between local signalling and further transport Development, February 15, 2005; 132(4): 659 - 666. [Abstract] [Full Text] [PDF]

				X. Lin Functions of heparan sulfate proteoglycans in cell signaling during development Development, December 15, 2004; 131(24): 6009 - 6021. [Abstract] [Full Text] [PDF]

				A. J. Zhu and M. P. Scott Incredible journey: how do developmental signals travel through tissue? Genes & Dev., December 15, 2004; 18(24): 2985 - 2997. [Abstract] [Full Text] [PDF]

				F. Moyrand and G. Janbon UGD1, Encoding the Cryptococcus neoformans UDP-Glucose Dehydrogenase, Is Essential for Growth at 37{degrees}C and for Capsule Biosynthesis Eukaryot. Cell, December 1, 2004; 3(6): 1601 - 1608. [Abstract] [Full Text] [PDF]

				J.-W. Huh, H.-Y. Yoon, H.-J. Lee, W.-B. Choi, S.-J. Yang, and S.-W. Cho Importance of Gly-13 for the Coenzyme Binding of Human UDP-glucose Dehydrogenase J. Biol. Chem., September 3, 2004; 279(36): 37491 - 37498. [Abstract] [Full Text] [PDF]

				N. Perrimon, U. Hacker, B. Sanson, and T. Tabata Wingless, Hedgehog and Heparan Sulfate Proteoglycans Development, June 1, 2004; 131(11): 2509 - 2513. [Full Text] [PDF]

				D. J. Bornemann, J. E. Duncan, W. Staatz, S. Selleck, and R. Warrior Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways Development, May 1, 2004; 131(9): 1927 - 1938. [Abstract] [Full Text] [PDF]

				S. Takeo, M. Fujise, T. Akiyama, H. Habuchi, N. Itano, T. Matsuo, T. Aigaki, K. Kimata, and H. Nakato In Vivo Hyaluronan Synthesis upon Expression of the Mammalian Hyaluronan Synthase Gene in Drosophila J. Biol. Chem., April 30, 2004; 279(18): 18920 - 18925. [Abstract] [Full Text] [PDF]

				C. Han, T. Y. Belenkaya, M. Khodoun, M. Tauchi, X. Lin, and X. Lin Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation Development, April 1, 2004; 131(7): 1563 - 1575. [Abstract] [Full Text] [PDF]

				T. Tabata and Y. Takei Morphogens, their identification and regulation Development, February 15, 2004; 131(4): 703 - 712. [Abstract] [Full Text] [PDF]

				Y. Takei, Y. Ozawa, M. Sato, A. Watanabe, and T. Tabata Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans Development, January 1, 2004; 131(1): 73 - 82. [Abstract] [Full Text] [PDF]

				S. C. Desbordes and B. Sanson The glypican Dally-like is required for Hedgehog signalling in the embryonic epidermis of Drosophila Development, December 22, 2003; 130(25): 6245 - 6255. [Abstract] [Full Text] [PDF]

				R. J. Bink, H. Habuchi, Z. Lele, E. Dolk, J. Joore, G.-J. Rauch, R. Geisler, S. W. Wilson, J. den Hertog, K. Kimata, et al. Heparan Sulfate 6-O-Sulfotransferase Is Essential for Muscle Development in Zebrafish J. Biol. Chem., August 15, 2003; 278(33): 31118 - 31127. [Abstract] [Full Text] [PDF]

				S. Kamiyama, T. Suda, R. Ueda, M. Suzuki, R. Okubo, N. Kikuchi, Y. Chiba, S. Goto, H. Toyoda, K. Saigo, et al. Molecular Cloning and Identification of 3'-Phosphoadenosine 5'-Phosphosulfate Transporter J. Biol. Chem., July 3, 2003; 278(28): 25958 - 25963. [Abstract] [Full Text] [PDF]

				Y. Bontemps, B. Vuillermoz, F. Antonicelli, C. Perreau, J.-L. Danan, F.-X. Maquart, and Y. Wegrowski Specific Protein-1 Is a Universal Regulator of UDP-glucose Dehydrogenase Expression: ITS POSITIVE INVOLVEMENT IN TRANSFORMING GROWTH FACTOR-{beta} SIGNALING AND INHIBITION IN HYPOXIA J. Biol. Chem., June 6, 2003; 278(24): 21566 - 21575. [Abstract] [Full Text] [PDF]

				B.-T. Kim, K. Tsuchida, J. Lincecum, H. Kitagawa, M. Bernfield, and K. Sugahara Identification and Characterization of Three Drosophila melanogaster Glucuronyltransferases Responsible for the Synthesis of the Conserved Glycosaminoglycan-Protein Linkage Region of Proteoglycans. TWO NOVEL HOMOLOGS EXHIBIT BROAD SPECIFICITY TOWARD OLIGOSACCHARIDES FROM PROTEOGLYCANS, GLYCOPROTEINS, AND GLYCOSPHINGOLIPIDS J. Biol. Chem., March 7, 2003; 278(11): 9116 - 9124. [Abstract] [Full Text] [PDF]

				H.-Y. Hwang and H. R. Horvitz The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development PNAS, October 29, 2002; 99(22): 14218 - 14223. [Abstract] [Full Text] [PDF]

				S. L. Holmen, A. Salic, C. R. Zylstra, M. W. Kirschner, and B. O. Williams A Novel Set of Wnt-Frizzled Fusion Proteins Identifies Receptor Components That Activate beta -Catenin-dependent Signaling J. Biol. Chem., September 13, 2002; 277(38): 34727 - 34735. [Abstract] [Full Text] [PDF]

				S. Yamada, Y. Okada, M. Ueno, S. Iwata, S. S. Deepa, S. Nishimura, M. Fujita, I. Van Die, Y. Hirabayashi, and K. Sugahara Determination of the Glycosaminoglycan-Protein Linkage Region Oligosaccharide Structures of Proteoglycans from Drosophila melanogaster and Caenorhabditis elegans J. Biol. Chem., August 23, 2002; 277(35): 31877 - 31886. [Abstract] [Full Text] [PDF]

				J. L. Moriarity, K. J. Hurt, A. C. Resnick, P. B. Storm, W. Laroy, R. L. Schnaar, and S. H. Snyder UDP-glucuronate Decarboxylase, a Key Enzyme in Proteoglycan Synthesis. CLONING, CHARACTERIZATION, AND LOCALIZATION J. Biol. Chem., May 3, 2002; 277(19): 16968 - 16975. [Abstract] [Full Text] [PDF]

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				N. B. Schwartz and M. Domowicz Chondrodysplasias due to proteoglycan defects Glycobiology, April 1, 2002; 12(4): 57R - 68R. [Abstract] [Full Text] [PDF]

				D. Liu, Z. Shriver, G. Venkataraman, Y. El Shabrawi, and R. Sasisekharan Tumor cell surface heparan sulfate as cryptic promoters or inhibitors of tumor growth and metastasis PNAS, January 22, 2002; 99(2): 568 - 573. [Abstract] [Full Text] [PDF]