TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes

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[Abstract] [Full Text] [PDF]

W. V. Cardoso and J. Lu
Regulation of early lung morphogenesis: questions, facts and controversies
Development, May 1, 2006; 133(9): 1611 - 1624.
[Abstract] [Full Text] [PDF]

B. Bandyopadhyay, J. Fan, S. Guan, Y. Li, M. Chen, D. T. Woodley, and W. Li
A "traffic control" role for TGF{beta}3: orchestrating dermal and epidermal cell motility during wound healing
J. Cell Biol., March 27, 2006; 172(7): 1093 - 1105.
[Abstract] [Full Text] [PDF]

R. Kumar, J. C. Langer, and H.-W. Snoeck
Transforming growth factor-beta2 is involved in quantitative genetic variation in thymic involution
Blood, March 1, 2006; 107(5): 1974 - 1979.
[Abstract] [Full Text] [PDF]

T. Sasaki, Y. Ito, P. Bringas Jr, S. Chou, M. M. Urata, H. Slavkin, and Y. Chai
TGF{beta}-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development
Development, January 15, 2006; 133(2): 371 - 381.
[Abstract] [Full Text] [PDF]

E. V. Tchetina, J. Antoniou, M. Tanzer, D. J. Zukor, and A. R. Poole
Transforming Growth Factor-{beta}2 Suppresses Collagen Cleavage in Cultured Human Osteoarthritic Cartilage, Reduces Expression of Genes Associated with Chondrocyte Hypertrophy and Degradation, and Increases Prostaglandin E2 Production
Am. J. Pathol., January 1, 2006; 168(1): 131 - 140.
[Abstract] [Full Text] [PDF]

L. Ma, M.-F. Lu, R. J. Schwartz, and J. F. Martin
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
Development, December 15, 2005; 132(24): 5601 - 5611.
[Abstract] [Full Text] [PDF]

D. T. Wu, M. Bitzer, W. Ju, P. Mundel, and E. P. Bottinger
TGF-{beta} Concentration Specifies Differential Signaling Profiles of Growth Arrest/Differentiation and Apoptosis in Podocytes
J. Am. Soc. Nephrol., November 1, 2005; 16(11): 3211 - 3221.
[Abstract] [Full Text] [PDF]

J. Wang, N. Xu, X. Feng, N. Hou, J. Zhang, X. Cheng, Y. Chen, Y. Zhang, and X. Yang
Targeted Disruption of Smad4 in Cardiomyocytes Results in Cardiac Hypertrophy and Heart Failure
Circ. Res., October 14, 2005; 97(8): 821 - 828.
[Abstract] [Full Text] [PDF]

H.-P. Kim, B.-G. Kim, J. Letterio, and W. J. Leonard
Smad-dependent Cooperative Regulation of Interleukin 2 Receptor {alpha} Chain Gene Expression by T Cell Receptor and Transforming Growth Factor-{beta}
J. Biol. Chem., October 7, 2005; 280(40): 34042 - 34047.
[Abstract] [Full Text] [PDF]

K. Janssens, P. ten Dijke, S. Janssens, and W. Van Hul
Transforming Growth Factor-{beta}1 to the Bone
Endocr. Rev., October 1, 2005; 26(6): 743 - 774.
[Abstract] [Full Text] [PDF]

M. Kluppel, T. N. Wight, C. Chan, A. Hinek, and J. L. Wrana
Maintenance of chondroitin sulfation balance by chondroitin-4-sulfotransferase 1 is required for chondrocyte development and growth factor signaling during cartilage morphogenesis
Development, September 1, 2005; 132(17): 3989 - 4003.
[Abstract] [Full Text] [PDF]

C. Colarossi, Y. Chen, H. Obata, V. Jurukovski, L. Fontana, B. Dabovic, and D. B. Rifkin
Lung Alveolar Septation Defects in Ltbp-3-Null Mice
Am. J. Pathol., August 1, 2005; 167(2): 419 - 428.
[Abstract] [Full Text] [PDF]

L O'Rear, L Longobardi, M Torello, B K Law, H L Moses, F Chiarelli, and A Spagnoli
Signaling cross-talk between IGF-binding protein-3 and transforming growth factor-{beta} in mesenchymal chondroprogenitor cell growth
J. Mol. Endocrinol., June 1, 2005; 34(3): 723 - 737.
[Abstract] [Full Text] [PDF]

				A. Horowitz and M. Simons Branching Morphogenesis Circ. Res., October 10, 2008; 103(8): 784 - 795. [Abstract] [Full Text] [PDF]

				P. Durani, N. Occleston, S. O'Kane, and M. W. J. Ferguson Avotermin: A Novel Antiscarring Agent International Journal of Lower Extremity Wounds, September 1, 2008; 7(3): 160 - 168. [Abstract] [PDF]

				H. Chen, F. Zhuang, Y-H. Liu, B. Xu, P. del Moral, W. Deng, Y. Chai, M. Kolb, J. Gauldie, D. Warburton, et al. TGF-{beta} receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung Eur. Respir. J., August 1, 2008; 32(2): 285 - 295. [Abstract] [Full Text] [PDF]

				D Obler, A L Juraszek, L B Smoot, and M R Natowicz Double outlet right ventricle: aetiologies and associations J. Med. Genet., August 1, 2008; 45(8): 481 - 497. [Abstract] [Full Text] [PDF]

				M. M. Hauri-Hohl, S. Zuklys, M. P. Keller, L. T. Jeker, T. Barthlott, A. M. Moon, J. Roes, and G. A. Hollander TGF-{beta} signaling in thymic epithelial cells regulates thymic involution and postirradiation reconstitution Blood, August 1, 2008; 112(3): 626 - 634. [Abstract] [Full Text] [PDF]

				K. Niessen, Y. Fu, L. Chang, P. A. Hoodless, D. McFadden, and A. Karsan Slug is a direct Notch target required for initiation of cardiac cushion cellularization J. Cell Biol., July 28, 2008; 182(2): 315 - 325. [Abstract] [Full Text] [PDF]

				N. Ambalavanan, T. Nicola, J. Hagood, A. Bulger, R. Serra, J. Murphy-Ullrich, S. Oparil, and Y.-F. Chen Transforming growth factor-{beta} signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung Am J Physiol Lung Cell Mol Physiol, July 1, 2008; 295(1): L86 - L95. [Abstract] [Full Text] [PDF]

				E. Roussa, O. Oehlke, B. Rahhal, S. Heermann, S. Heidrich, M. Wiehle, and K. Krieglstein Transforming Growth Factor {beta} Cooperates with Persephin for Dopaminergic Phenotype Induction Stem Cells, July 1, 2008; 26(7): 1683 - 1694. [Abstract] [Full Text] [PDF]

				W. V. Ingman and R. L. Jones Cytokine knockouts in reproduction: the use of gene ablation to dissect roles of cytokines in reproductive biology Hum. Reprod. Update, March 1, 2008; 14(2): 179 - 192. [Abstract] [Full Text] [PDF]

				P. F. van Loo, E. A. F. Mahtab, L. J. Wisse, J. Hou, F. Grosveld, G. Suske, S. Philipsen, and A. C. Gittenberger-de Groot Transcription Factor Sp3 Knockout Mice Display Serious Cardiac Malformations Mol. Cell. Biol., December 15, 2007; 27(24): 8571 - 8582. [Abstract] [Full Text] [PDF]

				B. C. Lin, R. Sullivan, Y. Lee, S. Moran, E. Glover, and C. A. Bradfield Deletion of the Aryl Hydrocarbon Receptor-associated Protein 9 Leads to Cardiac Malformation and Embryonic Lethality J. Biol. Chem., December 7, 2007; 282(49): 35924 - 35932. [Abstract] [Full Text] [PDF]

				V. Todorovic, D. Frendewey, D. E. Gutstein, Y. Chen, L. Freyer, E. Finnegan, F. Liu, A. Murphy, D. Valenzuela, G. Yancopoulos, et al. Long form of latent TGF-{beta} binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling Development, October 15, 2007; 134(20): 3723 - 3732. [Abstract] [Full Text] [PDF]

				L. A. Compton, D. A. Potash, C. B. Brown, and J. V. Barnett Coronary Vessel Development Is Dependent on the Type III Transforming Growth Factor {beta} Receptor Circ. Res., October 12, 2007; 101(8): 784 - 791. [Abstract] [Full Text] [PDF]

				L. Song, W. Yan, X. Chen, C.-x. Deng, Q. Wang, and K. Jiao Myocardial Smad4 Is Essential for Cardiogenesis in Mouse Embryos Circ. Res., August 3, 2007; 101(3): 277 - 285. [Abstract] [Full Text] [PDF]

				A. Spagnoli, L. O'Rear, R. L. Chandler, F. Granero-Molto, D. P. Mortlock, A. E. Gorska, J. A. Weis, L. Longobardi, A. Chytil, K. Shimer, et al. TGF-{beta} signaling is essential for joint morphogenesis J. Cell Biol., July 30, 2007; 177(6): 1105 - 1117. [Abstract] [Full Text] [PDF]

				M. Bujak and N. G. Frangogiannis The role of TGF-{beta} signaling in myocardial infarction and cardiac remodeling Cardiovasc Res, May 1, 2007; 74(2): 184 - 195. [Abstract] [Full Text] [PDF]

				S. Kuure, A. Popsueva, M. Jakobson, K. Sainio, and H. Sariola Glycogen Synthase Kinase-3 Inactivation and Stabilization of beta-Catenin Induce Nephron Differentiation in Isolated Mouse and Rat Kidney Mesenchymes J. Am. Soc. Nephrol., April 1, 2007; 18(4): 1130 - 1139. [Abstract] [Full Text] [PDF]

				J. A. Williams, B. L. Loeys, L. U. Nwakanma, H. C. Dietz, P. J. Spevak, N. D. Patel, K. Francois, J. DeBacker, V. L. Gott, L. A. Vricella, et al. Early Surgical Experience With Loeys-Dietz: A New Syndrome of Aggressive Thoracic Aortic Aneurysm Disease Ann. Thorac. Surg., February 1, 2007; 83(2): S757 - S763. [Abstract] [Full Text] [PDF]

				H. G. R. Thompson, J. D. Mih, T. B. Krasieva, B. J. Tromberg, and S. C. George Epithelial-derived TGF-beta2 modulates basal and wound-healing subepithelial matrix homeostasis Am J Physiol Lung Cell Mol Physiol, December 1, 2006; 291(6): L1277 - L1285. [Abstract] [Full Text] [PDF]

				K. Jiao, M. Langworthy, L. Batts, C. B. Brown, H. L. Moses, and H. S. Baldwin Tgf{beta} signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development Development, November 15, 2006; 133(22): 4585 - 4593. [Abstract] [Full Text] [PDF]

				W. Qi, X. Chen, J. Holian, E. Mreich, S. Twigg, R. E. Gilbert, and C. A. Pollock Transforming growth factor-beta1 differentially mediates fibronectin and inflammatory cytokine expression in kidney tubular cells Am J Physiol Renal Physiol, November 1, 2006; 291(5): F1070 - F1077. [Abstract] [Full Text] [PDF]

				K. Mesbah, A. Camus, C. Babinet, and J. Barra Mutation in the Trap{alpha}/Ssr1 Gene, Encoding Translocon-Associated Protein {alpha}, Results in Outflow Tract Morphogenetic Defects. Mol. Cell. Biol., October 1, 2006; 26(20): 7760 - 7771. [Abstract] [Full Text] [PDF]

				K.R. Barnett, C. Schilling, C.R. Greenfeld, D. Tomic, and J.A. Flaws Ovarian follicle development and transgenic mouse models Hum. Reprod. Update, September 1, 2006; 12(5): 537 - 555. [Abstract] [Full Text] [PDF]

				E. Roussa, M. Wiehle, N. Dunker, S. Becker-Katins, O. Oehlke, and K. Krieglstein Transforming Growth Factor {beta} Is Required for Differentiation of Mouse Mesencephalic Progenitors into Dopaminergic Neurons In Vitro and In Vivo: Ectopic Induction in Dorsal Mesencephalon Stem Cells, September 1, 2006; 24(9): 2120 - 2129. [Abstract] [Full Text] [PDF]

				C. Park, K. Lavine, Y. Mishina, C.-X. Deng, D. M. Ornitz, and K. Choi Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation Development, September 1, 2006; 133(17): 3473 - 3484. [Abstract] [Full Text] [PDF]

				C. S. K. Mayanil, A. Pool, H. Nakazaki, A. C. Reddy, B. Mania-Farnell, B. Yun, D. George, D. G. McLone, and E. G. Bremer Regulation of Murine TGFbeta2 by Pax3 during Early Embryonic Development J. Biol. Chem., August 25, 2006; 281(34): 24544 - 24552. [Abstract] [Full Text] [PDF]

				M. D'Antonio, A. Droggiti, M. L. Feltri, J. Roes, L. Wrabetz, R. Mirsky, and K. R. Jessen TGFbeta Type II Receptor Signaling Controls Schwann Cell Death and Proliferation in Developing Nerves. J. Neurosci., August 15, 2006; 26(33): 8417 - 8427. [Abstract] [Full Text] [PDF]

				R. L Jones, C. Stoikos, J. K Findlay, and L. A Salamonsen TGF-{beta} superfamily expression and actions in the endometrium and placenta. Reproduction, August 1, 2006; 132(2): 217 - 232. [Abstract] [Full Text] [PDF]

				S. Biswas, T. L. Criswell, S. E. Wang, and C. L. Arteaga Inhibition of Transforming Growth Factor-{beta} Signaling in Human Cancer: Targeting a Tumor Suppressor Network as a Therapeutic Strategy. Clin. Cancer Res., July 15, 2006; 12(14): 4142 - 4146. [Full Text] [PDF]

				D. Sheppard Transforming Growth Factor {beta}: A Central Modulator of Pulmonary and Airway Inflammation and Fibrosis. Proceedings of the ATS, July 1, 2006; 3(5): 413 - 417. [Abstract] [Full Text] [PDF]