Temporally-regulated retinoic acid depletion produces specific neural crest, ocular and nervous system defects

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Altman, J. and Bayer, S. A (1982). Development of the cranial nerve ganglia and related nuclei in the rat. Adv. Anat. Embryol. Cell Biol 74, 1-90.[Medline]

Amedee-Manesme, O., Furr, H. C. and Olson, J. A (1984). The correlation between liver vitamin A concentrations in micro-(needle biopsy) and macro samples of human liver specimens obtained at autopsy. Am. J. Clin. Nutr 39, 315-319.[Abstract/Free Full Text]

Anzano, M. A., Lamb, A. J. and Olson, J. A (1979). Growth, appetite, sequence of pathological signs and survival following the induction of rapid, synchronous vitamin A deficiency in the rat. J. Nutr 109, 1419-1431.[Abstract/Free Full Text]

Barua, A. B., Kostic, D., Barua, M. and Olson, J. A (1995). Determination of retinol and retinoic acid in capillary blood by high performance liquid chromatography. J. Liq. Chrom 18, 1459-1471.

Bedo, G., Santisteban, A. and Aranda, A (1989). Retinoic acid regulates growth hormone gene expression. Nature 339, 231-234.[Medline]

Collins, M. D., Tzimas, G., Burgin, H., Hummler, H. and Nau, H (1995). Single versus multiple dose administration of all-trans-retinoic acid during organogenesis: differentiation metabolism and transplacental kinetics in rat and rabbit. Tox. Appl. Pharm 130, 9-18.[Medline]

Dickman, E. D. and Smith, S. M (1995). Selective regulation ofcardiomyocyte gene expression and cardiac morphogenesis by retinoic acid. Dev. Dyn 206, 39-48.

Davila, M. E., Norris, L., Cleary, M. P. and Ross, C. A (1985). Vitamin A during lactation: relationship of maternal diet to milk vitamin A content and to the vitamin A status of lactating rats and their pups. J. Nutr 115, 1033-1041.[Abstract/Free Full Text]

Dersch, H. and Zile, M. H (1993). Induction of normal cardiovascular development in the vitamin A-deprived quail embryo by natural retinoids. Dev. Biol 160, 424-433.[Medline]

Dolle, P., Ruberte, E., Leroy, P., Morriss-Kay, G. and Chambon, P (1990). Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development 110, 1133-1151.[Abstract/Free Full Text]

Dyson, E., Sucov, H. M., Kubalak, S. W., Schmid-Schonbein, G. E., DeLano, F. A., Evans, R. M., Ross, J. M., Jr. and Chien, K. R (1995). Atrial-like phenotype is associated with embryonic ventricular failure in retinoid X receptor/ mice. Proc. Natl. Acad. Sci. USA 92, 7386-7390.[Abstract/Free Full Text]

Furr, H. C., Cooper, D. A. and Olson, J. A (1986). Separation of retinyl esters by non-aqueous reversed-phased high performance liquid chromatography. J. Chrom 378, 45-53.[Medline]

Graw, J (1996). Genetic aspects of embryonic eye development in vertebrates. Dev. Genet 18, 181-197.[Medline]

Grondona, J. M., Kastner, P., Gansmuller, A., Decimo, D., Chambon, P. and Mark, M (1996). Retinal dysplasia and degeneration in RAR2/RAR 2 compound mutant mice. Development 122, 2173-2188.[Abstract]

Gu, H., Marth, J. D., Orban, P. C., Mossmann, H. and Rajewsky, K (1994). Deletion of a DNA polymerasegene segment in T cells using cell type-specific gene targeting. Science 265, 103-106.[Abstract/Free Full Text]

Henion, P. D. and Weston, J. A (1994). Retinoic acid selectively promotes the survival and proliferation of neurogenic precursors in cultured neural crest cell populations. Dev. Biol 161, 243-250.[Medline]

Ito, Y., Zile, M., DeLuca, H. F. and Ahrens, H. M (1974). Metabolism of retinoic acid in vitamin A-deficient rats. Biochim. Biophys. Acta 369, 338-350.

Kastner, P., Grondona, J. M., Mark, M., Gansmuller, A., LeMeur, M., Decimo, D., Vonesch, J.-L., Dolle, P. and Chambon, P (1994). Genetic analysis of RXRdevelopmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis. Cell 78, 987-1003.[Medline]

Lohnes, D., Mark, M., Mendelsohn, C., Dolle, P., Dierich, A., Gorry, P., Gansmuller, A. and Chambon, P (1994). Function of the retinoic acid receptors (RARs) during development. I. Craniofacial and skeletal abnormalities in RAR double mutants. Development 120, 2733-2748.

Lohnes, D., Mark, M., Mendelsohn, C., Dolle, P., Decimo, D., LeMeur, M., Dierich, A., Gorry, P. and Chambon, P (1995). Developmental roles of the retinoic acid receptors. J. Steroid Biochem. Molec. Biol 53, 475-486.[Medline]

Maden, M., Gale, E., Kostetskii, I., and Zile, M (1996). Vitamin A-deficient quail embryos have half a hindbrain and other neural defects. Current Biol 6, 417-426.[Medline]

Mangelsdorf, D. J., Borgmeyer, U., Heyman, R. A., Zhou, J. Y., Ong, E. S., Oro, A. E., Kakizuka, A. and Evans, R. M (1992). Characterization of three RXR genes that mediate the action of 9-cis-retinoic acid. Genes Dev 6, 329-344.[Abstract/Free Full Text]

Mason, K. E (1935). Foetal death, prolonged gestation and difficult parturition in the rat as a result of vitamin A deficiency. Am. J. Anat 57, 303-349.

McAvoy, J. W (1980). Induction of the eye lens. Differentiation 17, 137-149.[Medline]

McCaffery, P., Lee, M. O., Wagner, M. A., Sladek, N. E. and Drager, U. C (1992). Asymmetrical retinoic acid synthesis in the dorsoventral axis of the retina. Development 115, 371-382.[Abstract]

Mendelsohn, C. Lohnes, D., Decimo, D., Lufkin, T., LeMeur, M., Chambon, P. and Mark, M (1994). Function of the retinoic acid receptors (RARs) during development. (II) Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development 120, 2749-2771.[Abstract]

Morriss-Kay, G (1993). Retinoic acid and craniofacial development: molecules and morphogenesis. BioEssays 15, 9-15.[Medline]

Morriss-Kay, G. M. and Sokolova, N (1996). Embryonic development and pattern formation. FASEB J 10, 961-968.[Abstract]

Napoli, J. L. and A. M. McCormick (1981). Tissue dependence of retinoic acid metabolism in vivo. Biochim. Biophys. Acta 666, 165-175.[Medline]

Noden, D. M (1991). Vertebrate craniofacial development: the relation between ontogenetic process and morophological outcome. Brain Behav. Evol 38, 190-225.[Medline]

Reeves, P. G., Nielsen, F. H. and Fahey, G. C., Jr (1993). AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76A rodent diet. J. Nutr 123, 1939-1951.[Abstract/Free Full Text]

Rhodes, S. J., Chen, R., DiMattia, G. E., Scully, L. M., Kalla, K. A., Lin, S. C., Yu, V. C. and Rosenfeld, M. G (1993). A tissue-specific enhancer confers Pit-1-dependent morphogen inducibility and autoregulation on the pit-1 gene. Genes Dev 7, 913-932.[Abstract/Free Full Text]

Rogers, W. E. and Bieri, J. G (1969). Vitamin A deficiency in the rat prior to weaning. Proc. Soc. Exp. Biol 132, 622-624.[Medline]

Schwind, J. L (1928). The development of the hypophysis cerebri of the albino rat. Am. J. Anat 41, 295-319.

Simmons, D. M., Voss, J. W., Ingraham, H. A., Holloway, J. M., Broide, R. S., Rosenfeld, M. G. and Swanson, L. W (1990). Pituitary cell phenotypes involve cell-specific Pit-1 mRNA translation and synergistic interactions with other classes of transcription factors. Genes Dev 4, 695-711.[Abstract/Free Full Text]

Smith, J. E (1990). Preparation of vitamin A-deficient rats and mice. Meth. Enzymol 190, 229-236.[Medline]

Sucov, H. M., Dyson, E., Gumeringer, C. L., Price, J., Chien, K. R. and Evans, R. M (1994). RXRmutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis. Genes Dev 8, 1007-1018.[Abstract/Free Full Text]

Takahashi, Y. I., Smith, J. E. and Goodman, D. S (1977). Vitamin A and retinol-binding protein metabolism during fetal development in the rat. Am. J. Physiol 233, 263-.

Tamarin, A., Crawley, A., Lee, J. and Tickle, C (1984). Analysis of upper beak defects in chicken embryos following treatment with retinoic acid. J. Embryol. Exp. Morph 84, 105-123.[Medline]

Thompson, J. N., Howell, J. M. and Pitt, G. A. J (1964). Vitamin A and reproduction in rats. Proc. Roy. Soc. (Biol.) 159, 510-533.

Tini, M., Fraser, R. A. and Giguere, V (1995). Functional interactions between retinoic acid receptor-related orphan nuclear receptor (ROR) and the retinoic acid receptors in the regulation of the F-crystallin promoter. J. Biol. Chem 270, 20156-20161.[Abstract/Free Full Text]

Thaller, C. and Eichele, G (1987). Identification and spatial distribution of retinoids in the developing chick limb bud. Nature 327, 625-628.[Medline]

Wallingford, J. C. and Underwood, B. A (1987). Vitamin A status needed to maintain vitamin A concentrations in nonhepatic tissues of the pregnant rat. J. Nutr 117, 1410-1415.[Abstract/Free Full Text]

Warkany, J. and Schraffenberger, E (1946). Congenital malformations induced in rats by maternal vitamin A deficiency. I. Defects of the eye. Arch. Ophth 35, 150-169.

Wellik, D. M. and DeLuca, H. F (1995). Retinol in addition to retinoic acid is required for successful gestation in vitamin A-deficient rats. Biol. Reprod 53, 1392-1397.[Abstract]

Wilson, J. G., Roth, C. B. and Warkany, J (1953). An analysis of the syndrome of malformations induced by maternal vitamin A deficiency. Effects of restoration of vitamin A at various times during gestation. Am J. Anat 92, 189-217.[Medline]

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				C E Decock, C M Breusegem, E H Van Aken, B P Leroy, C M Van Den Broecke, and J R Delanghe High {beta}-trace protein concentration in the fluid of an orbital cyst associated with bilateral colobomatous microphthalmos Br. J. Ophthalmol., June 1, 2007; 91(6): 836 - 838. [Full Text] [PDF]

				D. Chambers, L. Wilson, M. Maden, and A. Lumsden RALDH-independent generation of retinoic acid during vertebrate embryogenesis by CYP1B1 Development, April 1, 2007; 134(7): 1369 - 1383. [Abstract] [Full Text] [PDF]

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				W. V. Cardoso and J. Lu Regulation of early lung morphogenesis: questions, facts and controversies Development, May 1, 2006; 133(9): 1611 - 1624. [Abstract] [Full Text] [PDF]

				L. Liu and L. J. Gudas Disruption of the Lecithin:Retinol Acyltransferase Gene Makes Mice More Susceptible to Vitamin A Deficiency J. Biol. Chem., December 2, 2005; 280(48): 40226 - 40234. [Abstract] [Full Text] [PDF]

				N. Matt, V. Dupe, J.-M. Garnier, C. Dennefeld, P. Chambon, M. Mark, and N. B. Ghyselinck Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells Development, November 1, 2005; 132(21): 4789 - 4800. [Abstract] [Full Text] [PDF]

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				J. C. White, V. N. Shankar, M. Highland, M. L. Epstein, H. F. DeLuca, and M. Clagett-Dame Defects in embryonic hindbrain development and fetal resorption resulting from vitamin A deficiency in the rat are prevented by feeding pharmacological levels of all-trans-retinoic acid PNAS, November 10, 1998; 95(23): 13459 - 13464. [Abstract] [Full Text] [PDF]

				B Mascrez, M Mark, A Dierich, N. Ghyselinck, P Kastner, and P Chambon The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development Development, January 12, 1998; 125(23): 4691 - 4707. [Abstract] [PDF]

				H Kempf, C Linares, P Corvol, and J. Gasc Pharmacological inactivation of the endothelin type A receptor in the early chick embryo: a model of mispatterning of the branchial arch derivatives Development, January 12, 1998; 125(24): 4931 - 4941. [Abstract] [PDF]

				P Ruiz-Lozano, S. Smith, G Perkins, S. Kubalak, G. Boss, H. Sucov, R. Evans, and K. Chien Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos Development, January 2, 1998; 125(3): 533 - 544. [Abstract] [PDF]

				F. Grun, Y. Hirose, S. Kawauchi, T. Ogura, and K. Umesono Aldehyde Dehydrogenase 6, a Cytosolic Retinaldehyde Dehydrogenase Prominently Expressed in Sensory Neuroepithelia during Development J. Biol. Chem., December 22, 2000; 275(52): 41210 - 41218. [Abstract] [Full Text] [PDF]