Temporally-regulated retinoic acid depletion produces specific neural crest, ocular and nervous system defects

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				C E Decock, C M Breusegem, and B P Leroy Authors' response Br J Ophthalmol, November 1, 2008; 92(11): 1569 - 1569. [Full Text] [PDF]

				F. Chen, T. J. Desai, J. Qian, K. Niederreither, J. Lu, and W. V. Cardoso Inhibition of Tgf{beta} signaling by endogenous retinoic acid is essential for primary lung bud induction Development, August 15, 2007; 134(16): 2969 - 2979. [Abstract] [Full Text] [PDF]

				C E Decock, C M Breusegem, E H Van Aken, B P Leroy, C M Van Den Broecke, and J R Delanghe High {beta}-trace protein concentration in the fluid of an orbital cyst associated with bilateral colobomatous microphthalmos Br J Ophthalmol, June 1, 2007; 91(6): 836 - 838. [Full Text] [PDF]

				D. Chambers, L. Wilson, M. Maden, and A. Lumsden RALDH-independent generation of retinoic acid during vertebrate embryogenesis by CYP1B1 Development, April 1, 2007; 134(7): 1369 - 1383. [Abstract] [Full Text] [PDF]

				J. Morcillo, J. R. Martinez-Morales, F. Trousse, Y. Fermin, J. C. Sowden, and P. Bovolenta Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH Development, August 15, 2006; 133(16): 3179 - 3190. [Abstract] [Full Text] [PDF]

				A. Molotkov, N. Molotkova, and G. Duester Retinoic acid guides eye morphogenetic movements via paracrine signaling but is unnecessary for retinal dorsoventral patterning Development, May 15, 2006; 133(10): 1901 - 1910. [Abstract] [Full Text] [PDF]

				W. V. Cardoso and J. Lu Regulation of early lung morphogenesis: questions, facts and controversies Development, May 1, 2006; 133(9): 1611 - 1624. [Abstract] [Full Text] [PDF]

				L. Liu and L. J. Gudas Disruption of the Lecithin:Retinol Acyltransferase Gene Makes Mice More Susceptible to Vitamin A Deficiency J. Biol. Chem., December 2, 2005; 280(48): 40226 - 40234. [Abstract] [Full Text] [PDF]

				N. Matt, V. Dupe, J.-M. Garnier, C. Dennefeld, P. Chambon, M. Mark, and N. B. Ghyselinck Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells Development, November 1, 2005; 132(21): 4789 - 4800. [Abstract] [Full Text] [PDF]

				S. M. O'Byrne, N. Wongsiriroj, J. Libien, S. Vogel, I. J. Goldberg, W. Baehr, K. Palczewski, and W. S. Blaner Retinoid Absorption and Storage Is Impaired in Mice Lacking Lecithin:Retinol Acyltransferase (LRAT) J. Biol. Chem., October 21, 2005; 280(42): 35647 - 35657. [Abstract] [Full Text] [PDF]

				I. O. Sirbu, L. Gresh, J. Barra, and G. Duester Shifting boundaries of retinoic acid activity control hindbrain segmental gene expression Development, June 1, 2005; 132(11): 2611 - 2622. [Abstract] [Full Text] [PDF]

				H. K.W. Tse, M. B.W. Leung, A. S. Woolf, A. L. Menke, N. D. Hastie, J. A. Gosling, C.-P. Pang, and A. S.W. Shum Implication of Wt1 in the Pathogenesis of Nephrogenic Failure in a Mouse Model of Retinoic Acid-Induced Caudal Regression Syndrome Am. J. Pathol., May 1, 2005; 166(5): 1295 - 1307. [Abstract] [Full Text] [PDF]

				J. Shiotsugu, Y. Katsuyama, K. Arima, A. Baxter, T. Koide, J. Song, R. A. S. Chandraratna, and B. Blumberg Multiple points of interaction between retinoic acid and FGF signaling during embryonic axis formation Development, June 1, 2004; 131(11): 2653 - 2667. [Abstract] [Full Text] [PDF]

				V. Dupe, N. Matt, J.-M. Garnier, P. Chambon, M. Mark, and N. B. Ghyselinck A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment PNAS, November 25, 2003; 100(24): 14036 - 14041. [Abstract] [Full Text] [PDF]

				C. Wongtrakool, S. Malpel, J. Gorenstein, J. Sedita, M. I. Ramirez, T. M. Underhill, and W. V. Cardoso Down-regulation of Retinoic Acid Receptor {alpha} Signaling Is Required for Sacculation and Type I Cell Formation in the Developing Lung J. Biol. Chem., November 21, 2003; 278(47): 46911 - 46918. [Abstract] [Full Text] [PDF]

				X. Fan, A. Molotkov, S.-I. Manabe, C. M. Donmoyer, L. Deltour, M. H. Foglio, A. E. Cuenca, W. S. Blaner, S. A. Lipton, and G. Duester Targeted Disruption of Aldh1a1 (Raldh1) Provides Evidence for a Complex Mechanism of Retinoic Acid Synthesis in the Developing Retina Mol. Cell. Biol., July 1, 2003; 23(13): 4637 - 4648. [Abstract] [Full Text] [PDF]

				J. M. Lampert, J. Holzschuh, S. Hessel, W. Driever, K. Vogt, and J. von Lintig Provitamin A conversion to retinal via the {beta},{beta}-carotene-15,15'-oxygenase (bcox) is essential for pattern formation and differentiation during zebrafish embryogenesis Development, May 15, 2003; 130(10): 2173 - 2186. [Abstract] [Full Text] [PDF]

				K. Niederreither, J. Vermot, V. Fraulob, P. Chambon, and P. Dolle Retinaldehyde dehydrogenase 2 (RALDH2)- independent patterns of retinoic acid synthesis in the mouse embryo PNAS, December 10, 2002; 99(25): 16111 - 16116. [Abstract] [Full Text] [PDF]

				X. E, L. Zhang, J. Lu, P. Tso, W. S. Blaner, M. S. Levin, and E. Li Increased Neonatal Mortality in Mice Lacking Cellular Retinol-binding Protein II J. Biol. Chem., September 20, 2002; 277(39): 36617 - 36623. [Abstract] [Full Text] [PDF]

				G. Begemann, T. F. Schilling, G.-J. Rauch, R. Geisler, and P. W. Ingham The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain Development, August 15, 2001; 128(16): 3081 - 3094. [Abstract] [Full Text] [PDF]

				O. Wendling, N. B. Ghyselinck, P. Chambon, and M. Mark Roles of retinoic acid receptors in early embryonic morphogenesis and hindbrain patterning Development, June 1, 2001; 128(11): 2031 - 2038. [Abstract] [Full Text] [PDF]

				M. Mori, N. B. Ghyselinck, P. Chambon, and M. Mark Systematic Immunolocalization of Retinoid Receptors in Developing and Adult Mouse Eyes Invest. Ophthalmol. Vis. Sci., May 1, 2001; 42(6): 1312 - 1318. [Abstract] [Full Text]

				S. A. Ross, P. J. McCaffery, U. C. Drager, and L. M. De Luca Retinoids in Embryonal Development Physiol Rev, July 1, 2000; 80(3): 1021 - 1054. [Abstract] [Full Text] [PDF]

				S Malpel, C Mendelsohn, and W. Cardoso Regulation of retinoic acid signaling during lung morphogenesis Development, January 7, 2000; 127(14): 3057 - 3067. [Abstract] [PDF]

				J. W. Jaeger, I. H. Carlson, and W. P. Porter Endocrine, immune, and behavioral effects of aldicarb (carbamate), atrazine (triazine) and nitrate (fertilizer) mixtures at groundwater concentrations Toxicology and Industrial Health, February 1, 1999; 15(1-2): 133 - 151. [Abstract] [PDF]

				J. C. White, V. N. Shankar, M. Highland, M. L. Epstein, H. F. DeLuca, and M. Clagett-Dame Defects in embryonic hindbrain development and fetal resorption resulting from vitamin A deficiency in the rat are prevented by feeding pharmacological levels of all-trans-retinoic acid PNAS, November 10, 1998; 95(23): 13459 - 13464. [Abstract] [Full Text] [PDF]

				B Mascrez, M Mark, A Dierich, N. Ghyselinck, P Kastner, and P Chambon The RXRalpha ligand-dependent activation function 2 (AF-2) is important for mouse development Development, January 12, 1998; 125(23): 4691 - 4707. [Abstract] [PDF]

				H Kempf, C Linares, P Corvol, and J. Gasc Pharmacological inactivation of the endothelin type A receptor in the early chick embryo: a model of mispatterning of the branchial arch derivatives Development, January 12, 1998; 125(24): 4931 - 4941. [Abstract] [PDF]

				P Ruiz-Lozano, S. Smith, G Perkins, S. Kubalak, G. Boss, H. Sucov, R. Evans, and K. Chien Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos Development, January 2, 1998; 125(3): 533 - 544. [Abstract] [PDF]

				F. Grun, Y. Hirose, S. Kawauchi, T. Ogura, and K. Umesono Aldehyde Dehydrogenase 6, a Cytosolic Retinaldehyde Dehydrogenase Prominently Expressed in Sensory Neuroepithelia during Development J. Biol. Chem., December 22, 2000; 275(52): 41210 - 41218. [Abstract] [Full Text] [PDF]