The Drosophila sugarless gene modulates Wingless signaling and encodes an enzyme involved in polysaccharide biosynthesis

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Structural Analysis of Glycosaminoglycans in Drosophila and Caenorhabditis elegans and Demonstration That tout-velu, a Drosophila Gene Related to EXT Tumor Suppressors, Affects Heparan Sulfate in Vivo
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H. Habuchi, M. Tanaka, O. Habuchi, K. Yoshida, H. Suzuki, K. Ban, and K. Kimata
The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the Targeted N-Sulfoglucosamine
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A. D. Lander and S. B. Selleck
The Elusive Functions of Proteoglycans: In Vivo Veritas
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C Goutte, W Hepler, K. Mickey, and J. Priess
aph-2 encodes a novel extracellular protein required for GLP-1-mediated signaling
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				X. Zhong, T. Desilva, L. Lin, P. Bodine, R. A. Bhat, E. Presman, J. Pocas, M. Stahl, and R. Kriz Regulation of Secreted Frizzled-related Protein-1 by Heparin J. Biol. Chem., July 13, 2007; 282(28): 20523 - 20533. [Abstract] [Full Text] [PDF]

				R.-J. Hung, H.-S. Chien, R.-Z. Lin, C.-T. Lin, J. Vatsyayan, H.-L. Peng, and H.-Y. Chang Comparative Analysis of Two UDP-glucose Dehydrogenases in Pseudomonas aeruginosa PAO1 J. Biol. Chem., June 15, 2007; 282(24): 17738 - 17748. [Abstract] [Full Text] [PDF]

				X. Zhu, L. M. Stevens, and D. Stein Synthesis of the sulfate donor PAPS in either the Drosophila germline or somatic follicle cells can support embryonic dorsal-ventral axis formation Development, April 15, 2007; 134(8): 1465 - 1469. [Abstract] [Full Text] [PDF]

				D. Vigetti, M. Ori, M. Viola, A. Genasetti, E. Karousou, M. Rizzi, F. Pallotti, I. Nardi, V. C. Hascall, G. De Luca, et al. Molecular Cloning and Characterization of UDP-glucose Dehydrogenase from the Amphibian Xenopus laevis and Its Involvement in Hyaluronan Synthesis J. Biol. Chem., March 24, 2006; 281(12): 8254 - 8263. [Abstract] [Full Text] [PDF]

				D. Beis, T. Bartman, S.-W. Jin, I. C. Scott, L. A. D'Amico, E. A. Ober, H. Verkade, J. Frantsve, H. A. Field, A. Wehman, et al. Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development Development, September 15, 2005; 132(18): 4193 - 4204. [Abstract] [Full Text] [PDF]

				X. Zhu, J. Sen, L. Stevens, J. S. Goltz, and D. Stein Drosophila Pipe protein activity in the ovary and the embryonic salivary gland does not require heparan sulfate glycosaminoglycans Development, September 1, 2005; 132(17): 3813 - 3822. [Abstract] [Full Text] [PDF]

				J. Vatsyayan, H.-L. Peng, and H.-Y. Chang Analysis of Human UDP-Glucose Dehydrogenase Gene Promoter: Identification of an Sp1 Binding Site Crucial for the Expression of the Large Transcript J. Biochem., June 1, 2005; 137(6): 703 - 709. [Abstract] [Full Text] [PDF]

				E. R. Bastow, K. J. Lamb, J. C. Lewthwaite, A. C. Osborne, E. Kavanagh, C. P. D. Wheeler-Jones, and A. A. Pitsillides Selective Activation of the MEK-ERK Pathway Is Regulated by Mechanical Stimuli in Forming Joints and Promotes Pericellular Matrix Formation J. Biol. Chem., March 25, 2005; 280(12): 11749 - 11758. [Abstract] [Full Text] [PDF]

				N. Kotani, S. Kitazume, K. Kamimura, S. Takeo, T. Aigaki, H. Nakato, and Y. Hashimoto Characterization of Drosophila Aspartic Proteases That Induce the Secretion of a Golgi-Resident Transferase, Heparan Sulfate 6-O-Sulfotransferase J. Biochem., March 1, 2005; 137(3): 315 - 322. [Abstract] [Full Text] [PDF]

				K. Weber, N. Johnson, D. Champlin, and A. Patty Many P-Element Insertions Affect Wing Shape in Drosophila melanogaster Genetics, March 1, 2005; 169(3): 1461 - 1475. [Abstract] [Full Text] [PDF]

				X. Franch-Marro, O. Marchand, E. Piddini, S. Ricardo, C. Alexandre, and J.-P. Vincent Glypicans shunt the Wingless signal between local signalling and further transport Development, February 15, 2005; 132(4): 659 - 666. [Abstract] [Full Text] [PDF]

				X. Lin Functions of heparan sulfate proteoglycans in cell signaling during development Development, December 15, 2004; 131(24): 6009 - 6021. [Abstract] [Full Text] [PDF]

				A. J. Zhu and M. P. Scott Incredible journey: how do developmental signals travel through tissue? Genes & Dev., December 15, 2004; 18(24): 2985 - 2997. [Abstract] [Full Text] [PDF]

				N. Perrimon, U. Hacker, B. Sanson, and T. Tabata Wingless, Hedgehog and Heparan Sulfate Proteoglycans Development, June 1, 2004; 131(11): 2509 - 2513. [Full Text] [PDF]

				B. J. Sommer, J. J. Barycki, and M. A. Simpson Characterization of Human UDP-glucose Dehydrogenase: CYS-276 IS REQUIRED FOR THE SECOND OF TWO SUCCESSIVE OXIDATIONS J. Biol. Chem., May 28, 2004; 279(22): 23590 - 23596. [Abstract] [Full Text] [PDF]

				D. J. Bornemann, J. E. Duncan, W. Staatz, S. Selleck, and R. Warrior Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways Development, May 1, 2004; 131(9): 1927 - 1938. [Abstract] [Full Text] [PDF]

				S. Takeo, M. Fujise, T. Akiyama, H. Habuchi, N. Itano, T. Matsuo, T. Aigaki, K. Kimata, and H. Nakato In Vivo Hyaluronan Synthesis upon Expression of the Mammalian Hyaluronan Synthase Gene in Drosophila J. Biol. Chem., April 30, 2004; 279(18): 18920 - 18925. [Abstract] [Full Text] [PDF]

				C. Han, T. Y. Belenkaya, M. Khodoun, M. Tauchi, X. Lin, and X. Lin Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation Development, April 1, 2004; 131(7): 1563 - 1575. [Abstract] [Full Text] [PDF]

				T. Tabata and Y. Takei Morphogens, their identification and regulation Development, February 15, 2004; 131(4): 703 - 712. [Abstract] [Full Text] [PDF]

				Y. Takei, Y. Ozawa, M. Sato, A. Watanabe, and T. Tabata Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans Development, January 1, 2004; 131(1): 73 - 82. [Abstract] [Full Text] [PDF]

				M. S. Hickery, M. T. Bayliss, J. Dudhia, J. C. Lewthwaite, J. C. W. Edwards, and A. A. Pitsillides Age-related Changes in the Response of Human Articular Cartilage to IL-1{alpha} and Transforming Growth Factor-{beta} (TGF-{beta}): CHONDROCYTES EXHIBIT A DIMINISHED SENSITIVITY TO TGF-{beta} J. Biol. Chem., December 26, 2003; 278(52): 53063 - 53071. [Abstract] [Full Text] [PDF]

				S. C. Desbordes and B. Sanson The glypican Dally-like is required for Hedgehog signalling in the embryonic epidermis of Drosophila Development, December 22, 2003; 130(25): 6245 - 6255. [Abstract] [Full Text] [PDF]

				R. J. Bink, H. Habuchi, Z. Lele, E. Dolk, J. Joore, G.-J. Rauch, R. Geisler, S. W. Wilson, J. den Hertog, K. Kimata, et al. Heparan Sulfate 6-O-Sulfotransferase Is Essential for Muscle Development in Zebrafish J. Biol. Chem., August 15, 2003; 278(33): 31118 - 31127. [Abstract] [Full Text] [PDF]

				Q. Ch'ng, L. Williams, Y. S. Lie, M. Sym, J. Whangbo, and C. Kenyon Identification of Genes That Regulate a Left-Right Asymmetric Neuronal Migration in Caenorhabditis elegans Genetics, August 1, 2003; 164(4): 1355 - 1367. [Abstract] [Full Text] [PDF]

				S. Kamiyama, T. Suda, R. Ueda, M. Suzuki, R. Okubo, N. Kikuchi, Y. Chiba, S. Goto, H. Toyoda, K. Saigo, et al. Molecular Cloning and Identification of 3'-Phosphoadenosine 5'-Phosphosulfate Transporter J. Biol. Chem., July 3, 2003; 278(28): 25958 - 25963. [Abstract] [Full Text] [PDF]

				B.-T. Kim, K. Tsuchida, J. Lincecum, H. Kitagawa, M. Bernfield, and K. Sugahara Identification and Characterization of Three Drosophila melanogaster Glucuronyltransferases Responsible for the Synthesis of the Conserved Glycosaminoglycan-Protein Linkage Region of Proteoglycans. TWO NOVEL HOMOLOGS EXHIBIT BROAD SPECIFICITY TOWARD OLIGOSACCHARIDES FROM PROTEOGLYCANS, GLYCOPROTEINS, AND GLYCOSPHINGOLIPIDS J. Biol. Chem., March 7, 2003; 278(11): 9116 - 9124. [Abstract] [Full Text] [PDF]

				C. A. Micchelli, I. The, E. Selva, V. Mogila, and N. Perrimon rasp, a putative transmembrane acyltransferase, is required for Hedgehog signaling Development, March 4, 2003; 129(4): 843 - 851. [Abstract] [Full Text] [PDF]

				H.-Y. Hwang and H. R. Horvitz The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development PNAS, October 29, 2002; 99(22): 14218 - 14223. [Abstract] [Full Text] [PDF]

				T. Y. Belenkaya, C. Han, H. J. Standley, X. Lin, D. W. Houston, J. Heasman, and X. Lin pygopus encodes a nuclear protein essential for Wingless/Wnt signaling Development, September 1, 2002; 129(17): 4089 - 4101. [Abstract] [Full Text] [PDF]

				R. Muller, F. Altmann, D. Zhou, and T. Hennet The Drosophila melanogaster brainiac Protein Is a Glycolipid-specific beta 1,3N-Acetylglucosaminyltransferase J. Biol. Chem., August 30, 2002; 277(36): 32417 - 32420. [Abstract] [Full Text] [PDF]