Genetic control of brain morphogenesis through Otx gene dosage requirement

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Acampora, D., Mazan, S., Lallemand, Y., Avantaggiato, V., Maury, M., Simeone, A. and Br\236let, P (1995). Forebrain and midbrain regions are deleted in Otx2/ mutants due to a defective anterior neuroectoderm specification during gastrulation. Development 121, 3279-3290.[Abstract]

Acampora, D., Mazan, S., Avantaggiato, V., Barone, P., Tuorto, F.,Lallemand, Y., Br\236let, P. and Simeone, A (1996). Epilepsy and brain abnormalities in mice lacking Otx1 gene. Nature Genet 14, 218-222.[Medline]

Altman, J. and Bayer, S. A (1988). Development of the rat thalamus: I. Mosaic organization of the thalamic neuroepithelium. J. Comp. Neurol 275, 346-377.[Medline]

Ang, S.-L (1996). The brain organization. Nature 380, 25-27.[Medline]

Ang, S.-L., Jin, O., Rhinn, M., Daigle, N., Stevenson, L. and Rossant, J (1996). A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development 122, 243-252.[Abstract]

Avantaggiato, V., Acampora, D., Tuorto, F. and Simeone, A (1996). Retinoic acid induces stage-specific repatterning of the rostral central nervous system. Dev. Biol 175, 347-357.[Medline]

Bally-Cuif, L. and Wassef, M (1995). Determination events in the nervous system of the vertebrate embryo. Curr. Opin. Genet. Dev 5, 450-458.[Medline]

Bulfone, A., Smiga, S. M., Shimamura, K., Peterson, A., Puelles, L. and Rubenstein, J. L. R (1995). T-brain-1: A homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. Neuron 15, 63-78.[Medline]

Cohen, S. M. and Jurgens, G (1991). Drosophila headlines. Trends Genet 7, 267-272.[Medline]

Crossley, P. H. and Martin, G. R (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryos. Development 121, 439-451.[Abstract]

Crossley, P. H., Martinez, S. and Martin, G. R (1996). Midbrain development induced by FGF8 in the chick embryo. Nature 380, 66-68.[Medline]

Danielian, P. S. and McMahon, A. P (1996). Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature 383, 332-334.[Medline]

Echelard, Y., Epstein, D. J., St-Jacques, B., Shen, L., Mohler, J., McMahon, J. A. and McMahon, A. P (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.[Medline]

Figdor, M. C. and Stern, C. D (1993). Segmental organization of embryonic diencephalon. Nature 363, 630-634.[Medline]

Finkelstein, R. and Perrimon, N (1990). The orthodenticle gene is regulated by bicoid and torso and specifies Drosophila head development. Nature 346, 485-488.[Medline]

Gallera, J (1971). Primary induction in birds. Adv. Morph 9, 149-180.[Medline]

Hirth, F., Therianos, S., Loop, T., Gehring, W. J., Reichert, H. and Furukubo-Tokunaga, K (1995). Developmental defects in brain segmentation caused by mutations of the homeobox gene orthodenticle and empy spiracles in Drosophila. Neuron 15, 1-20.[Medline]

Ingham, P. W. and Martinez Arias, A (1992). Boundaries and fields in early embryos. Cell 68, 221-235.[Medline]

Joyner, A. L (1996). Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development. Trends Genet 12, 15-20.[Medline]

Lee, S M. K., Danielian, P. S., Fritzsch, B. and McMahon, A. P (1997). Evidence that FGF8 signalling from the midbrain-hindbrain junction regulates growth and polarity in the developing midbrain. Development 124, 959-969.[Abstract]

Marin, F. and Puelles, L (1994). Patterning of the embryonic avian midbrain after experimental inversions: a polarizing activity from the isthmus. Dev. Biol 163, 19-37.[Medline]

Martinez, S., Wassef, M. and Alvarado-Mallart, R.-M (1991). Induction of a mesencephalic phenotype in the 2 day-old chick prosencephalon is preceded by the early expression of the homeobox gene en. Neuron 6, 971-981.[Medline]

Matsuo, I., Kuratani, S., Kimura, C., Takeda, N. and Aizawa, S (1995). Mouse Otx2 functions in the formation and patterning of rostral head. Genes Dev 9, 2646-2658.[Abstract/Free Full Text]

McMahon, A. P., Joyner, A. L., Bradley, A. and McMahon, J. A (1992). The midbrain-hindbrain phenotype of Wnt-1/Wnt-1 mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum. Cell 69, 581-595.[Medline]

Meinhardt, H (1983). Cell determination boundaries as organizing: regions for secondary embryonic fields. Dev. Biol 96, 375-385.[Medline]

Millet, S., Bloch-Gallego, E., Simeone, A. and Alvarado-Mallart, R.-M (1996). Is the caudal limit of Otx2 gene expression a marker of the midbrain/hindbrain boundary? A study using a chick- Otx2 riboprobe and chick/quail homotopic grafts. Development 122, 3785-3797.[Abstract]

Pellegrini, M., Mansouri, A., Simeone, A., Boncinelli, E. and Gruss, P (1996). Dentate gyrus formation requires Emx2. Development 122, 3893-3898.[Abstract]

Perrimon, N (1994). The genetic basis of patterned baldness in Drosophila. Cell 76, 781-784.[Medline]

Puelles, L. and Rubenstein, J. L. R (1993). Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggest a neuromeric organization. Trends Neuros 16, 472-479.[Medline]

Rowitch, D. H. and McMahon, A. P (1995). Pax-2 expression in the murine neural plate precedes and encompasses the expression domains of Wnt-1 and En-1. Mech. Dev 52, 3-8.[Medline]

Royet, J. and Finkelstein, R (1995). Pattern formation in Drosophila head development: the role of the orthodenticle homeobox gene. Development 121, 3561-3572.[Abstract]

Rubenstein, J. L. R., Martinez, S., Shimamura, K. and Puelles, L (1994). The embryonic vertebrate forebrain: the prosomeric model. Science 266, 578-580.[Free Full Text]

Ruiz i Altaba, A (1994). Pattern formation in the vertebrate neural plate. Trends Neurosci 17, 233-243.[Medline]

Simeone, A., Acampora, D., Gulisano, M., Stornaiuolo, A. and Boncinelli, E (1992). Nested expression domains of four homeobox genes in developing rostral brain. Nature 358, 687-690.[Medline]

Simeone, A., Gulisano, M., Acampora, D., Stornaiuolo, A., Rambaldi, M. and Boncinelli, E (1992). Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex. EMBO J 11, 2541-2550.[Medline]

Simeone, A., Acampora, D., Mallamaci, A., Stornaiuolo, A., D'Apice, M. R., Nigro, V. and Boncinelli, E (1993). A vertebrate gene related to orthodenticle contains a homeodomain of the bicoid class and demarcates anterior neuroectoderm in the gastrulating mouse embryo. EMBO J 12, 2735-2747.[Medline]

Simeone, A., D'Apice, M. R., Nigro,V., Casanova, J., Graziani, F., Acampora, D. and Avantaggiato, V (1994). Orthopedia , a novel homeobox-containing gene expressed in the developing central nervous system of both mouse and Drosophila. Neuron 13, 83-101.[Medline]

Simeone, A., Avantaggiato, V., Moroni, M. C., Mavilio, F., Arra, C., Cotelli,F., Nigro, V. and Acampora, D (1995). Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system. Mech. Dev 51, 83-98.[Medline]

Stoykova, A. and Gruss, P (1994). Roles of Pax -genes in developing and adult brain as suggested by expression patterns. J. Neurosci 14, 1395-1412.[Abstract]

Storey, K. G., Crossley, J. M., De Robertis, E. M., Norris, W. E. and Stern, C. D (1992). Neural induction and regionalisation in the chick embryo. Development 114, 729-741.[Abstract]

Tanaka, A., Miyamoto, K., Minamino, N., Takeda, M., Sato, B., Matsuo, H. and Matsumoto, K (1992). Cloning and characterization of an androgen-induced growth factor essential for the androgen-dependent growth of mouse mammary carcinoma cells. Proc. Natl. Acad. Sci. USA 89, 8928-8932.[Abstract/Free Full Text]

Thomas, K. R. and Capecchi, M. R (1990). Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346, 847-850.[Medline]

Thor, S (1995). The genetics of brain development: conserved programs in files and mice. Neuron 15, 975-977.[Medline]

Vaage, S (1969). The segmentation of the primitive neural tube in chick embryos ( Gallus domesticus ). Adv. Anat. Embryol. Cell Biol 41, 1-87.

Walther, C. and Gruss, P (1991). Pax-6 , a murine paired box gene, is expressed in the developing CNS. Development 113, 1435-1449.[Abstract]

Yoshida, M., Suda, Y., Matsuo, I., Miyamoto, N., Takeda, N., Kuratani, S. and Aizawa, S (1997). Emx1 and Emx2 functions in development of dorsal telencephalon. Development 124, 101-111.[Abstract]

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				S. Scholpp, I. Foucher, N. Staudt, D. Peukert, A. Lumsden, and C. Houart Otx1l, Otx2 and Irx1b establish and position the ZLI in the diencephalon Development, September 1, 2007; 134(17): 3167 - 3176. [Abstract] [Full Text] [PDF]

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				G. Griesel, D. Treichel, P. Collombat, J. Krull, A. Zembrzycki, W. M. R. van den Akker, P. Gruss, A. Simeone, and A. Mansouri Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border Development, May 1, 2006; 133(9): 1779 - 1787. [Abstract] [Full Text] [PDF]

				B. Vernay, M. Koch, F. Vaccarino, J. Briscoe, A. Simeone, R. Kageyama, and S.-L. Ang Otx2 Regulates Subtype Specification and Neurogenesis in the Midbrain J. Neurosci., May 11, 2005; 25(19): 4856 - 4867. [Abstract] [Full Text] [PDF]

				D. Kurokawa, N. Takasaki, H. Kiyonari, R. Nakayama, C. Kimura-Yoshida, I. Matsuo, and S. Aizawa Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm Development, July 15, 2004; 131(14): 3307 - 3317. [Abstract] [Full Text] [PDF]

				D. Kurokawa, H. Kiyonari, R. Nakayama, C. Kimura-Yoshida, I. Matsuo, and S. Aizawa Regulation of Otx2 expression and its functions in mouse forebrain and midbrain Development, July 15, 2004; 131(14): 3319 - 3331. [Abstract] [Full Text] [PDF]

				E. Puelles, A. Annino, F. Tuorto, A. Usiello, D. Acampora, T. Czerny, C. Brodski, S.-L. Ang, W. Wurst, and A. Simeone Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain Development, May 1, 2004; 131(9): 2037 - 2048. [Abstract] [Full Text] [PDF]

				C. Kimura-Yoshida, K. Kitajima, I. Oda-Ishii, E Tian, M. Suzuki, M. Yamamoto, T. Suzuki, M. Kobayashi, S. Aizawa, and I. Matsuo Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification Development, January 1, 2004; 131(1): 57 - 71. [Abstract] [Full Text] [PDF]

				C. Brodski, D. M. V. Weisenhorn, M. Signore, I. Sillaber, M. Oesterheld, V. Broccoli, D. Acampora, A. Simeone, and W. Wurst Location and Size of Dopaminergic and Serotonergic Cell Populations Are Controlled by the Position of the Midbrain-Hindbrain Organizer J. Neurosci., May 15, 2003; 23(10): 4199 - 4207. [Abstract] [Full Text] [PDF]

				T. Hide, J. Hatakeyama, C. Kimura-Yoshida, E Tian, N. Takeda, Y. Ushio, T. Shiroishi, S. Aizawa, and I. Matsuo Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice Development, March 11, 2003; 129(18): 4347 - 4357. [Abstract] [Full Text] [PDF]

				T. Brody and W. F. Odenwald Cellular diversity in the developing nervous system: a temporal view from Drosophila Development, March 10, 2003; 129(16): 3763 - 3770. [Abstract] [Full Text] [PDF]

				O. V. Lagutin, C. C. Zhu, D. Kobayashi, J. Topczewski, K. Shimamura, L. Puelles, H. R.C. Russell, P. J. McKinnon, L. Solnica-Krezel, and G. Oliver Six3 repression of Wnt signaling in the anterior neuroectoderm is essential for vertebrate forebrain development Genes & Dev., February 1, 2003; 17(3): 368 - 379. [Abstract] [Full Text] [PDF]

				Y. Zhang, T. Miki, T. Iwanaga, Y. Koseki, M. Okuno, Y. Sunaga, N. Ozaki, H. Yano, H. Koseki, and S. Seino Identification, Tissue Expression, and Functional Characterization of Otx3, a Novel Member of the Otx Family J. Biol. Chem., July 26, 2002; 277(31): 28065 - 28069. [Abstract] [Full Text] [PDF]

				A. Dohmoto, K. Shimizu, Y. Asada, and T. Maeda Quantitative Trait Loci on Chromosomes 10 and 11 Influencing Mandible Size of SMXA RI Mouse Strains J. Dent. Res., July 1, 2002; 81(7): 501 - 504. [Abstract] [Full Text] [PDF]

				L. A. Martin, S.-S. Tan, and D. Goldowitz Clonal Architecture of the Mouse Hippocampus J. Neurosci., May 1, 2002; 22(9): 3520 - 3530. [Abstract] [Full Text] [PDF]

				A. Glavic, J. L. Gomez-Skarmeta, and R. Mayor The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation Development, January 4, 2002; 129(7): 1609 - 1621. [Abstract] [Full Text] [PDF]

				J. Y. H. Li and A. L. Joyner Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression Development, December 15, 2001; 128(24): 4979 - 4991. [Abstract] [Full Text] [PDF]

				H. Toresson and K. Campbell A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice Development, December 1, 2001; 128(23): 4769 - 4780. [Abstract] [Full Text] [PDF]

				J. P. Martinez-Barbera, M. Signore, P. P. Boyl, E. Puelles, D. Acampora, R. Gogoi, F. Schubert, A. Lumsden, and A. Simeone Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2 Development, December 1, 2001; 128(23): 4789 - 4800. [Abstract] [Full Text] [PDF]

				D. Acampora, P. P. Boyl, M. Signore, J. P. Martinez-Barbera, C. Ilengo, E. Puelles, A. Annino, H. Reichert, G. Corte, and A. Simeone OTD/OTX2 functional equivalence depends on 5' and 3' UTR-mediated control of Otx2 mRNA for nucleo-cytoplasmic export and epiblast-restricted translation Development, December 1, 2001; 128(23): 4801 - 4813. [Abstract] [Full Text] [PDF]

				H.-G. Belting, G. Hauptmann, D. Meyer, S. Abdelilah-Seyfried, A. Chitnis, C. Eschbach, I. Soll, C. Thisse, B. Thisse, K. B. Artinger, et al. spiel ohne grenzen/pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer Development, November 1, 2001; 128(21): 4165 - 4176. [Abstract] [Full Text] [PDF]

				P. P. Boyl, M. Signore, D. Acampora, J. P. Martinez-Barbera, C. Ilengo, A. Annino, G. Corte, and A. Simeone Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR Development, August 1, 2001; 128(15): 2989 - 3000. [Abstract] [Full Text] [PDF]

				S. Tole and E. A. Grove Detailed Field Pattern Is Intrinsic to the Embryonic Mouse Hippocampus Early in Neurogenesis J. Neurosci., March 1, 2001; 21(5): 1580 - 1589. [Abstract] [Full Text] [PDF]

				J Hatakeyama, K Tomita, T Inoue, and R Kageyama Roles of homeobox and bHLH genes in specification of a retinal cell type Development, January 4, 2001; 128(8): 1313 - 1322. [Abstract] [PDF]

				A Liu and A. Joyner EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region Development, January 1, 2001; 128(2): 181 - 191. [Abstract] [PDF]

				Y Watanabe and H Nakamura Control of chick tectum territory along dorsoventral axis by Sonic hedgehog Development, January 3, 2000; 127(5): 1131 - 1140. [Abstract] [PDF]

				J Galceran, E. Miyashita-Lin, E Devaney, J. Rubenstein, and R Grosschedl Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1 Development, January 2, 2000; 127(3): 469 - 482. [Abstract] [PDF]

				C Irving and I Mason Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression Development, January 1, 2000; 127(1): 177 - 186. [Abstract] [PDF]