Direct neural induction and selective inhibition of mesoderm and epidermis inducers by Xnr3

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Hansen, C. S.
	Articles by Smith, W. C.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Hansen, C. S.
	Articles by Smith, W. C.

Condie, B. G. and Harland, R. M (1987). Posterior expression of a homeobox gene in early Xenopus embryos. Development 101, 93-105.[Abstract]

Cox, W. G. and Hemmati-Brivanlou, A (1995). Caudalization of neural fate by tissue recombination and bFGF. Development 121, 4349-4358.[Abstract]

Dale, L., Howes, G., Price, B. M. and Smith, J. C (1992). Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development. Development 115, 573-585.[Abstract]

Doniach, T (1993). Planar and vertical induction of anteroposterior pattern during the development of the amphibian central nervous system. J. Neurobiol 24, 1256-1275.[Medline]

Doniach, T., Phillips, C. R. and Gerhart, J. C (1992). Planar induction of anteroposterior pattern in the developing central nervous system of Xenopus laevis. Science 257, 542-545.[Abstract/Free Full Text]

Dworkin-Rastl, E., Kelly, D. B. and Dworkin, M. B (1986). Localization of specific mRNA sequences in Xenopuslaevis by in situ hybridization. J. Embryol. Exp. Morph 91, 153-168.[Medline]

Ecochard, V., Cayrol, C., Foulquier, F., Zaraisky, A. and Duprat, A. M (1995). A novel TGF-beta-like gene, fugacin, specifically expressed in the Spemann organizer of Xenopus. Dev. Biol 172, 699-703.[Medline]

Fainsod, A., Steinbeisser, H. and De Robertis, E. M (1994). On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo. EMBO J 13, 5015-5025.[Medline]

Graff, J. M., Thies, R. S., Song, J. J., Celeste, A. J. and Melton, D. A (1994). Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo. Cell 79, 169-179.[Medline]

Green, J. B., New, H. V. and Smith, J. C (1992). Responses of embryonic Xenopus cells to activin and FGF are separated by multiple dose thresholds and correspond to distinct axes of the mesoderm. Cell 71, 731-739.[Medline]

Grunz, H. and Tacke, L (1989). Neural differentiation of Xenopus laevisectoderm takes place after disaggregation and delayed reaggregation without inducer. Cell Differ. Dev 28, 211-217.[Medline]

Harland, R. M. and Misher, L (1988). Stability of RNA in developing Xenopus embryos and identification of a destabilizing sequence in TFIIIA messenger RNA. Development 102, 837-852.[Abstract/Free Full Text]

Hawley, S. H. B., Wunnenberg-Stapleton, K., Hashimoto, C., Laurent, M. N., Watabe, T., Blumberg, B. W. and Cho, K. W (1995). Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction. Genes Dev 9, 2923-2935.[Abstract/Free Full Text]

Hazama, M., Aono, A., Ueno, N., Fujisawa, Y (1995). Efficient expression of a heterodimer of bone morphogenetic protein subunits using a baculovirus expression system. Biochem. Biophys. Res. Comm 209, 3-.

Hemmati-Brivanlou, A. and Harland, R. M (1989). Expression of an engrailed-related protein is induced in the anterior neural ectoderm of early Xenopus embryos. Development 106, 611-617.[Abstract]

Hemmati-Brivanlou, A., Kelly, O. G. and Melton, D. A (1994). Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity. Cell 77, 283-295.[Medline]

Hemmati-Brivanlou, A. and Melton, D. A (1994). Inhibition of activin signaling promotes neuralization in Xenopus laevis. Cell 77, 273-281.[Medline]

Hemmati-Brivanlou, A., Stewart, R. M. and Harland, R. M (1990). Region-specific neural induction of an engrailed protein by anterior notochord in Xenopus. Science 250, 800-802.[Abstract/Free Full Text]

Hemmati-Brivanlou, A. and Thomsen, G. H (1995). Ventral mesodermal patterning in Xenopus embryos: expression patterns and activities of BMP-2 and BMP-4. Dev. Genet 17, 78-89.[Medline]

Jamrich, M., Sargent, T.D. and Dawid, I.B (1987). Cell-type-specific expression of epidermal cytokeratin genes during gastrulation of Xenopus laevis. Genes Dev 1, 124-132.[Abstract/Free Full Text]

Jones, C. M., Dale, L., Hogan, B. L. M., Wright, C. V. E. and Smith, J. C (1996). Bone morphogenetic protein-4 (BMP-4) acts during gastrula stages to cause ventralization of Xenopus embryos. Development 122, 1545-1554.[Abstract]

Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. and Hogan, B. L (1992). DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.[Abstract]

Jones, E. A. and Woodland, H. R (1989). Spatial aspects of neural induction in Xenopuslaevis. Development 107, 785-791.[Abstract/Free Full Text]

Jones, M., Hogan, B. L. M., Kuehn, M. R., Smith, J. C. and Wright, C. V. E (1995). Nodal-related signals induce axial mesoderm and dorsalized mesoderm during vertebrate gastrulation. Development 121, 3651-3662.[Abstract]

Keller, R. E (1975). Vital dye mapping of the gastrula and neurula of Xenopus laevis. I. Prospective areas and morphogenetic movements of the superficial layer. Dev. Biol 42, 222-241.[Medline]

Keller, R. E (1976). Vital dye mapping of the gastrula and neurula of Xenopus laevis. II. Prospective areas and morphogenetic movements of the deep layer. Dev. Biol 51, 118-137.[Medline]

Kengaku, M. and Okamoto, H (1993). Basic fibroblast growth factor induces differentiation of neural tube and neural crest lineages of cultured ectoderm cells from Xenopus gastrula. Development 119, 1067-1078.[Abstract]

Kessler, D. S. and Melton, D. A (1994). Vertebrate embryonic induction: mesodermal and neural patterning. Science 266, 596-604.[Abstract/Free Full Text]

Kingsley, D. M (1994). The TGF-superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 8, 133-146.[Free Full Text]

Kintner, C. R. and Melton, D. A (1987). Expression of Xenopus N-CAM RNA in ectoderm is an early response to neural induction. Development 99, 311-325.[Abstract]

Knecht, A. K., Good, P. J., Dawid, I. B. and Harland, R. M (1995). Dorsal-ventral patterning and differentiation of noggin-induced neural tissue in the absence of mesoderm. Development 121, 1927-1935.[Abstract]

Koenig, B. B., Cook, J. S., Wolsing, D. H., Ting, J., Tiesman, J. P., Correa, P. E., Olson, C. A., Pecquet, A. L., Ventura, F., Grant, R. A., Chen, G.-X., Wrana, J. L., Massague, J. and Rosenbaum, J. S (1994). Characterization and cloning of a receptor for BMP-2 and BMP-4 from NIH 3T3 cells. Mol. Cell. Biol 14, 5961-5974.[Abstract/Free Full Text]

K\232ster, M., Plessow, S., Clement, J. H., Lorenz, A., Tiedemann, H. and Kn\232chel, W (1991). Bone morphogenetic protein 4 (BMP-4), a member of the TGF-family, in early embryos of Xenopus laevis: analysis of mesoderm inducing activity. Mech. Dev 33, 191-200.[Medline]

Krieg, P. A., Varnum, S. M., Wormington, W. M. and Melton, D. A (1989). The mRNA encoding elongation factor 1-alpha (EF-1 alpha) is a major transcript at the midblastula transition in Xenopus. Dev. Biol 133, 93-100.[Medline]

Kunkel, T. A (1985). Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc. Natl. Acad. Sci. U.S.A 82, 488-492.[Abstract/Free Full Text]

Lamb, T. M. and Harland, R. M (1995). Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern. Development 121, 3627-3636.[Abstract]

Lamb, T. M., Knecht, A. K., Smith, W. C., Stachel, S. E., Economides, A. N., Stahl, N., Yancopolous, G. D. and Harland, R. M (1993). Neural induction by the secreted polypeptide noggin. Science 262, 713-718.[Abstract/Free Full Text]

Launay, C., Fromentoux, V., Shi, D.-L. and Boucaut, J.-C (1996). A truncated FGF receptor blocks neural induction by endogenous Xenopus inducers. Development 122, 869-880.[Abstract]

Lettice, L. A. and Slack, J. M. W (1993). Properties of the dorsalizing signal in gastrulae of Xenopuslaevis. Development 117, 263-271.[Abstract]

Mason, A (1994). Functional analysis of the cysteine residues of activin A. Mol. Endo 8, 325-332.[Abstract]

Matzuk, M. M, Lu, N., Vogel, H., Sellheyer, K., Roop, D. R. and Bradley, A (1995). Multiple defects and perinatal death in mice deficient in follistatin. Nature 374, 360-363.[Medline]

Melton, D. A., Kreig, P. A., Rebagliati, M. R., Maniatis, T., Zinn, K. and Green, M. R (1984). Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucl. Acid Res 12, 7035-7056.[Abstract/Free Full Text]

Piccolo, S., Sasai, Y., Lu, B. and De Robertis, E (1996). Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4. Cell 86, 589-598.[Medline]

Richter, K., Grunz, H. and Dawid, I. B (1988). Gene expression in the embryonic nervous system of Xenopus laevis. Proc. Natl. Acad. Sci. USA 85, 8086-8090.[Abstract/Free Full Text]

Ruiz i Altaba, A (1990). Neural expression of the Xenopus homeobox gene Xhox3 : evidence for a patterning neural signal that spreads through the ectoderm. Development 108, 595-604.[Abstract/Free Full Text]

Saha, M. S. and Grainger, R. M (1992). A labile period in the determination of the anterior-posterior axis during early neural development in Xenopus. Neuron 8, 1003-1014.[Medline]

Sasai, Y., Lu, B., Steinbeisseer, H., Geissert, D., Gont, L. K. and De Robertis, E. M (1994). Xenopus chordin: a novel dorsalizing factor activated by organizer-specific homeobox genes. Cell 79, 779-790.[Medline]

Sasai, Y., Lu, B., Steinbelsser, H. and De Robertis, E. M (1995). Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus. Nature 376, 333-336.[Medline]

Schulte-Merker, S., Smith, J. C. and Dale, L (1994). Effects of truncated activin and FGF receptors and of follistatin on the inducing activities of BVg1 and activin: does activin play a role in mesoderm induction?. EMBO J 13, 3533-3533.[Medline]

Sharpe, C. R., Fritz, A., De, R. E. and Gurdon, J. B (1987). A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction. Cell 50, 749-758.[Medline]

Shih, J. and Keller, R (1992). The epithelium of the dorsal marginal zone of Xenopus has organizer properties. Development 116, 887-99.[Abstract]

Slack, J. M (1993). Embryonic induction. Mech. Dev 41, 91-107.[Medline]

Smith, J. C., Price, B. M. J., Green, J. B. A., Weigel, D. and Herrmann, B. G (1991). Expression of the Xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction. Cell 67, 79-87.[Medline]

Smith, J. C. and Slack, J. M (1983). Dorsalization and neural induction: properties of the organizer in Xenopus laevis. J. Embryol.Exp.Morph 78, 299-317.[Medline]

Smith, W. C. and Harland, R. M (1992). Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos. Cell 70, 829-840.[Medline]

Smith, W. C. and Harland, R. M (1991). Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center. Cell 67, 753-765.[Medline]

Smith, W. C., Knecht, A. K., Wu, M. and Harland, R. M (1993). Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm. Nature 361, 547-549.[Medline]

Smith, W. C., McKendry, R. M., Ribisi, S. and Harland, R. M (1995). A nodal-related gene defines a physical and functional domain within the Spemann Organizer. Cell 82, 37-46.[Medline]

ten Dijke, P., Yamashita, H., Sampath, T. K., Reddi, A. H., Estevez, M.,Riddle, D. L., Ichijo, H., Heldin, C. H. and Miyazono, K (1994). Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4. J. Biol. Chem 269, 16985-16988.[Abstract/Free Full Text]

Thomsen, G., Woolf, T., Whitman, M., Sokol, S., Vaughan, J., Vale, W. and Melton, W (1990). Activins are expressed early in Xenopus embryogenesis and can induce axial mesoderm and anterior structures. Cell 63, 485-493.[Medline]

Turner, D. L. and Weintraub, H (1994). Expression of achaete-scute homolog 3 in Xenopus embryos converts ectodermal cells to a neural fate. Genes Dev 8, 1434-1447.[Abstract/Free Full Text]

Vodicka, M. A. and Gerhart, J. C (1995). Blastomere derivation and domains of gene expression in the Spemann Organizer of Xenopus laevis. Development 121, 3505-3518.[Abstract]

Wilson, P. A. and Hemmati-Brivanlou, A (1995). Induction of epidermis and inhibition of neural fate by Bmp-4. Nature 376, 331-333.[Medline]

Wright, C. V., Morita, E. A., Wilkin, D. J. and De, R. E (1990). The Xenopus XIHbox 6 homeo protein, a marker of posterior neural induction, is expressed in proliferating neurons. Development 109, 225-234.[Abstract]

Xu, J., McKeehan, K., Matsuzaki, K. and McKeehan, W. L (1995). Inhibin antagonizes inhibition of liver cell growth by activin by a dominant-negative mechanism. J. Biol. Chem 270, 6308-6313.[Abstract/Free Full Text]

Xu, R. H., Kim, J., Taira, M., Zhan, S., Sredni, D. and Kung, H. F (1995). A dominant negative bone morphogenetic protein 4 receptor causes neuralization in Xenopus ectoderm. Biochem. Biophys. Res. Comm 212, 212-219.[Medline]

Zhou, X., Sasaki, H., Lowe, L., Hogan, B. L. and Kuehn, M. R (1993). Nodal is a novel TGF-beta-like gene expressed in the mouse node during gastrulation. Nature 361, 543-547.[Medline]

Zimmerman, L. B., De Jesus-Escobar, J. M. and Harland, R. M (1996). The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein-4. Cell 86, 599-606.[Medline]

This article has been cited by other articles:

C. Linker and C. D. Stern
Neural induction requires BMP inhibition only as a late step, and involves signals other than FGF and Wnt antagonists
Development, November 15, 2004; 131(22): 5671 - 5681.
[Abstract] [Full Text] [PDF]

C. Yokota, M. Kofron, M. Zuck, D. W. Houston, H. Isaacs, M. Asashima, C. C. Wylie, and J. Heasman
A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor
Development, May 15, 2003; 130(10): 2199 - 2212.
[Abstract] [Full Text] [PDF]

G. Lupo, W. A. Harris, G. Barsacchi, and R. Vignali
Induction and patterning of the telencephalon in Xenopus laevis
Development, January 12, 2002; 129(23): 5421 - 5436.
[Abstract] [Full Text] [PDF]

I. Munoz-Sanjuan, E. Bell, C. R. Altmann, A. Vonica, and A. H. Brivanlou
Gene profiling during neural induction in Xenopus laevis: regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding protein
Development, January 12, 2002; 129(23): 5529 - 5540.
[Abstract] [Full Text] [PDF]

C. H. Ezal, C. D. Marion, and W. C. Smith
Primary Structure Requirements for Xenopus Nodal-related 3 and a Comparison with Regions Required by Xenopus Nodal-related 2
J. Biol. Chem., May 5, 2000; 275(19): 14124 - 14131.
[Abstract] [Full Text] [PDF]

S. Osada, Y Saijoh, A Frisch, C. Yeo, H Adachi, M Watanabe, M Whitman, H Hamada, and C. Wright
Activin/nodal responsiveness and asymmetric expression of a Xenopus nodal-related gene converge on a FAST-regulated module in intron 1
Development, January 6, 2000; 127(11): 2503 - 2514.
[Abstract] [PDF]

E Agius, M Oelgeschlager, O Wessely, C Kemp, and E. De Robertis
Endodermal Nodal-related signals and mesoderm induction in Xenopus
Development, January 3, 2000; 127(6): 1173 - 1183.
[Abstract] [PDF]

J. C. Baker, R. S.P. Beddington, and R. M. Harland
Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural development
Genes & Dev., December 1, 1999; 13(23): 3149 - 3159.
[Abstract] [Full Text]

C Chang and A Hemmati-Brivanlou
Xenopus GDF6, a new antagonist of noggin and a partner of BMPs
Development, January 8, 1999; 126(15): 3347 - 3357.
[Abstract] [PDF]

S. Osada and C. Wright
Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis
Development, January 6, 1999; 126(14): 3229 - 3240.
[Abstract] [PDF]

B. Sun, S. Bush, L. Collins-Racie, E. LaVallie, E. DiBlasio-Smith, N. Wolfman, J. McCoy, and H. Sive
derriere: a TGF-beta family member required for posterior development in Xenopus
Development, January 4, 1999; 126(7): 1467 - 1482.
[Abstract] [PDF]

E Pera, S Stein, and M Kessel
Ectodermal patterning in the avian embryo: epidermis versus neural plate
Development, January 1, 1999; 126(1): 63 - 73.
[Abstract] [PDF]

J. LeSueur and J. Graff
Spemann organizer activity of Smad10
Development, January 1, 1999; 126(1): 137 - 146.
[Abstract] [PDF]

F. Mariani and R. Harland
XBF-2 is a transcriptional repressor that converts ectoderm into neural tissue
Development, January 12, 1998; 125(24): 5019 - 5031.
[Abstract] [PDF]

K. Kroll, A. Salic, L. Evans, and M. Kirschner
Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation
Development, January 8, 1998; 125(16): 3247 - 3258.
[Abstract] [PDF]

T Nakayama, M. Snyder, S. Grewal, K Tsuneizumi, T Tabata, and J. Christian
Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning
Development, January 3, 1998; 125(5): 857 - 867.
[Abstract] [PDF]

J van der Wees, J. Schilthuis, C. Koster, H Diesveld-Schipper, G. Folkers, P. van der Saag, M. Dawson, K Shudo, B van der Burg, and A. Durston
Inhibition of retinoic acid receptor-mediated signalling alters positional identity in the developing hindbrain
Development, January 2, 1998; 125(3): 545 - 556.
[Abstract] [PDF]

K. Nakata, T. Nagai, J. Aruga, and K. Mikoshiba
Xenopus Zic3, a primary regulator both in neural and neural crest�development
PNAS, October 28, 1997; 94(22): 11980 - 11985.
[Abstract] [Full Text] [PDF]

K Sampath, A. Cheng, A Frisch, and C. Wright
Functional differences among Xenopus nodal-related genes in left-right axis determination
Development, January 9, 1997; 124(17): 3293 - 3302.
[Abstract] [PDF]

L. M. Bjorklund, R. Sanchez-Pernaute, S. Chung, T. Andersson, I. Y. C. Chen, K. St. P. McNaught, A.-L. Brownell, B. G. Jenkins, C. Wahlestedt, K.-S. Kim, et al.
From the Cover: Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
PNAS, February 19, 2002; 99(4): 2344 - 2349.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Hansen, C. S.

Articles by Smith, W. C.

Search for Related Content

PubMed

PubMed Citation

Articles by Hansen, C. S.

Articles by Smith, W. C.

				C. Yokota, M. Kofron, M. Zuck, D. W. Houston, H. Isaacs, M. Asashima, C. C. Wylie, and J. Heasman A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor Development, May 15, 2003; 130(10): 2199 - 2212. [Abstract] [Full Text] [PDF]

				G. Lupo, W. A. Harris, G. Barsacchi, and R. Vignali Induction and patterning of the telencephalon in Xenopus laevis Development, January 12, 2002; 129(23): 5421 - 5436. [Abstract] [Full Text] [PDF]

				I. Munoz-Sanjuan, E. Bell, C. R. Altmann, A. Vonica, and A. H. Brivanlou Gene profiling during neural induction in Xenopus laevis: regulation of BMP signaling by post-transcriptional mechanisms and TAB3, a novel TAK1-binding protein Development, January 12, 2002; 129(23): 5529 - 5540. [Abstract] [Full Text] [PDF]

				C. H. Ezal, C. D. Marion, and W. C. Smith Primary Structure Requirements for Xenopus Nodal-related 3 and a Comparison with Regions Required by Xenopus Nodal-related 2 J. Biol. Chem., May 5, 2000; 275(19): 14124 - 14131. [Abstract] [Full Text] [PDF]

				S. Osada, Y Saijoh, A Frisch, C. Yeo, H Adachi, M Watanabe, M Whitman, H Hamada, and C. Wright Activin/nodal responsiveness and asymmetric expression of a Xenopus nodal-related gene converge on a FAST-regulated module in intron 1 Development, January 6, 2000; 127(11): 2503 - 2514. [Abstract] [PDF]

				E Agius, M Oelgeschlager, O Wessely, C Kemp, and E. De Robertis Endodermal Nodal-related signals and mesoderm induction in Xenopus Development, January 3, 2000; 127(6): 1173 - 1183. [Abstract] [PDF]

				J. C. Baker, R. S.P. Beddington, and R. M. Harland Wnt signaling in Xenopus embryos inhibits Bmp4 expression and activates neural development Genes & Dev., December 1, 1999; 13(23): 3149 - 3159. [Abstract] [Full Text]

				C Chang and A Hemmati-Brivanlou Xenopus GDF6, a new antagonist of noggin and a partner of BMPs Development, January 8, 1999; 126(15): 3347 - 3357. [Abstract] [PDF]

				S. Osada and C. Wright Xenopus nodal-related signaling is essential for mesendodermal patterning during early embryogenesis Development, January 6, 1999; 126(14): 3229 - 3240. [Abstract] [PDF]

				B. Sun, S. Bush, L. Collins-Racie, E. LaVallie, E. DiBlasio-Smith, N. Wolfman, J. McCoy, and H. Sive derriere: a TGF-beta family member required for posterior development in Xenopus Development, January 4, 1999; 126(7): 1467 - 1482. [Abstract] [PDF]

				E Pera, S Stein, and M Kessel Ectodermal patterning in the avian embryo: epidermis versus neural plate Development, January 1, 1999; 126(1): 63 - 73. [Abstract] [PDF]

				J. LeSueur and J. Graff Spemann organizer activity of Smad10 Development, January 1, 1999; 126(1): 137 - 146. [Abstract] [PDF]

				F. Mariani and R. Harland XBF-2 is a transcriptional repressor that converts ectoderm into neural tissue Development, January 12, 1998; 125(24): 5019 - 5031. [Abstract] [PDF]

				K. Kroll, A. Salic, L. Evans, and M. Kirschner Geminin, a neuralizing molecule that demarcates the future neural plate at the onset of gastrulation Development, January 8, 1998; 125(16): 3247 - 3258. [Abstract] [PDF]

				T Nakayama, M. Snyder, S. Grewal, K Tsuneizumi, T Tabata, and J. Christian Xenopus Smad8 acts downstream of BMP-4 to modulate its activity during vertebrate embryonic patterning Development, January 3, 1998; 125(5): 857 - 867. [Abstract] [PDF]

				J van der Wees, J. Schilthuis, C. Koster, H Diesveld-Schipper, G. Folkers, P. van der Saag, M. Dawson, K Shudo, B van der Burg, and A. Durston Inhibition of retinoic acid receptor-mediated signalling alters positional identity in the developing hindbrain Development, January 2, 1998; 125(3): 545 - 556. [Abstract] [PDF]

				K. Nakata, T. Nagai, J. Aruga, and K. Mikoshiba Xenopus Zic3, a primary regulator both in neural and neural crest�development PNAS, October 28, 1997; 94(22): 11980 - 11985. [Abstract] [Full Text] [PDF]

				K Sampath, A. Cheng, A Frisch, and C. Wright Functional differences among Xenopus nodal-related genes in left-right axis determination Development, January 9, 1997; 124(17): 3293 - 3302. [Abstract] [PDF]

				L. M. Bjorklund, R. Sanchez-Pernaute, S. Chung, T. Andersson, I. Y. C. Chen, K. St. P. McNaught, A.-L. Brownell, B. G. Jenkins, C. Wahlestedt, K.-S. Kim, et al. From the Cover: Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model PNAS, February 19, 2002; 99(4): 2344 - 2349. [Abstract] [Full Text] [PDF]