Drosophila cubitus interruptus forms a negative feedback loop with patched and regulates expression of Hedgehog target genes

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Alexandre, C., Jacinto, A. and Ingham, P.W (1996). Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the Cubitus interruptus protein, a member of the GLI family of the zinc finger DNA-binding proteins. Genes Dev 10, 2003-2013.[Abstract/Free Full Text]

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				L. F. de Navas, D. L. Garaulet, and E. Sanchez-Herrero The Ultrabithorax Hox gene of Drosophila controls haltere size by regulating the Dpp pathway Development, November 15, 2006; 133(22): 4495 - 4506. [Abstract] [Full Text] [PDF]

				D. Kent, E. W. Bush, and J. E. Hooper Roadkill attenuates Hedgehog responses through degradation of Cubitus interruptus. Development, May 1, 2006; 133(10): 2001 - 2010. [Abstract] [Full Text] [PDF]

				S. K. Pallavi and L. S. Shashidhara Signaling interactions between squamous and columnar epithelia of the Drosophila wing disc J. Cell Sci., August 1, 2005; 118(15): 3363 - 3370. [Abstract] [Full Text] [PDF]

				S. Merabet, J. C.-G. Hombria, N. Hu, J. Pradel, and Y. Graba Hox-controlled reorganisation of intrasegmental patterning cues underlies Drosophila posterior spiracle organogenesis Development, July 1, 2005; 132(13): 3093 - 3102. [Abstract] [Full Text] [PDF]

				K. Kato, T. Chihara, and S. Hayashi Hedgehog and Decapentaplegic instruct polarized growth of cell extensions in the Drosophila trachea Development, November 1, 2004; 131(21): 5253 - 5261. [Abstract] [Full Text] [PDF]

				C. Kwon, R. Hays, J. Fetting, and T. V. Orenic Opposing inputs by Hedgehog and Brinker define a stripe of hairy expression in the Drosophila leg imaginal disc Development, June 1, 2004; 131(11): 2681 - 2692. [Abstract] [Full Text] [PDF]

				S. S. Blair Genetic mosaic techniques for studying Drosophila development Development, November 1, 2003; 130(21): 5065 - 5072. [Abstract] [Full Text] [PDF]

				W. Fu and N. E. Baker Deciphering synergistic and redundant roles of Hedgehog, Decapentaplegic and Delta that drive the wave of differentiation in Drosophila eye development Development, November 1, 2003; 130(21): 5229 - 5239. [Abstract] [Full Text] [PDF]

				C. Hosono, K. Takaira, R. Matsuda, and K. Saigo Functional subdivision of trunk visceral mesoderm parasegments in Drosophila is required for gut and trachea development Development, February 1, 2003; 130(3): 439 - 449. [Abstract] [Full Text] [PDF]

				K. E. Nybakken, C. W. Turck, D. J. Robbins, and J. M. Bishop Hedgehog-stimulated Phosphorylation of the Kinesin-related Protein Costal2 Is Mediated by the Serine/Threonine Kinase Fused J. Biol. Chem., June 28, 2002; 277(27): 24638 - 24647. [Abstract] [Full Text] [PDF]

				F. Chanut, A. Luk, and U. Heberlein A Screen for Dominant Modifiers of roDom, a Mutation That Disrupts Morphogenetic Furrow Progression in Drosophila, Identifies Groucho and Hairless as Regulators of atonal Expression Genetics, November 1, 2000; 156(3): 1203 - 1217. [Abstract] [Full Text]

				R. H. Goodman and S. Smolik CBP/p300 in cell growth, transformation, and development Genes & Dev., July 1, 2000; 14(13): 1553 - 1577. [Full Text]

				A Gallet, C Angelats, S Kerridge, and P. Therond Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila Development, January 12, 2000; 127(24): 5509 - 5522. [Abstract] [PDF]

				P. Svendsen, S. Marshall, M Kyba, and W. Brook The combgap locus encodes a zinc-finger protein that regulates cubitus interruptus during limb development in Drosophila melanogaster Development, January 10, 2000; 127(19): 4083 - 4093. [Abstract] [PDF]

				G. Campbell and A Tomlinson Transcriptional regulation of the Hedgehog effector CI by the zinc-finger gene combgap Development, January 10, 2000; 127(19): 4095 - 4103. [Abstract] [PDF]

				P Aza-Blanc, H. Lin, A Ruiz i Altaba, and T. Kornberg Expression of the vertebrate Gli proteins in Drosophila reveals a distribution of activator and repressor activities Development, January 10, 2000; 127(19): 4293 - 4301. [Abstract] [PDF]

				N Methot and K Basler Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus Development, January 9, 2000; 127(18): 4001 - 4010. [Abstract] [PDF]

				Q. Wang and R. Holmgren Nuclear import of cubitus interruptus is regulated by hedgehog via a mechanism distinct from Ci stabilization and Ci activation Development, January 7, 2000; 127(14): 3131 - 3139. [Abstract] [PDF]

				T Suzuki and K Saigo Transcriptional regulation of atonal required for Drosophila larval eye development by concerted action of eyes absent, sine oculis and hedgehog signaling independent of fused kinase and cubitus interruptus Development, January 4, 2000; 127(7): 1531 - 1540. [Abstract] [PDF]

				H. Park, C Bai, K. Platt, M. Matise, A Beeghly, C. Hui, M Nakashima, and A. Joyner Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation Development, January 4, 2000; 127(8): 1593 - 1605. [Abstract] [PDF]

				B. Charroux, C. Angelats, L. Fasano, S. Kerridge, and C. Vola The Levels of the bancal Product, a Drosophila Homologue of Vertebrate hnRNP K Protein, Affect Cell Proliferation and Apoptosis in Imaginal Disc Cells Mol. Cell. Biol., November 1, 1999; 19(11): 7846 - 7856. [Abstract] [Full Text] [PDF]

				D. N. Keys, D. L. Lewis, J. E. Selegue, B. J. Pearson, L. V. Goodrich, R. L. Johnson, J. Gates, M. P. Scott, and S. B. Carroll Recruitment of a hedgehog Regulatory Circuit in Butterfly Eyespot Evolution Science, January 22, 1999; 283(5401): 532 - 534. [Abstract] [Full Text]

				C Alexandre, M Lecourtois, and J Vincent Wingless and Hedgehog pattern Drosophila denticle belts by regulating the production of short-range signals Development, January 12, 1999; 126(24): 5689 - 5698. [Abstract] [PDF]

				Q. Wang and R. Holmgren The subcellular localization and activity of Drosophila cubitus interruptus are regulated at multiple levels Development, January 11, 1999; 126(22): 5097 - 5106. [Abstract] [PDF]

				P. Therond, B Limbourg Bouchon, A Gallet, F Dussilol, T Pietri, M van den Heuvel, and H Tricoire Differential requirements of the fused kinase for hedgehog signalling in the Drosophila embryo Development, January 9, 1999; 126(18): 4039 - 4051. [Abstract] [PDF]

				A Kopp, R. Blackman, and I Duncan Wingless, decapentaplegic and EGF receptor signaling pathways interact to specify dorso-ventral pattern in the adult abdomen of Drosophila Development, January 8, 1999; 126(16): 3495 - 3507. [Abstract] [PDF]

				J Hepker, R. Blackman, and R Holmgren Cubitus interruptus is necessary but not sufficient for direct activation of a wing-specific decapentaplegic enhancer Development, January 8, 1999; 126(16): 3669 - 3677. [Abstract] [PDF]

				R Hays, K. Buchanan, C Neff, and T. Orenic Patterning of Drosophila leg sensory organs through combinatorial signaling by hedgehog, decapentaplegic and wingless Development, January 7, 1999; 126(13): 2891 - 2899. [Abstract] [PDF]

				A Amin, Y Li, and R Finkelstein Hedgehog activates the EGF receptor pathway during Drosophila head development Development, January 6, 1999; 126(12): 2623 - 2630. [Abstract] [PDF]

				A Ruiz i Altaba Gli proteins encode context-dependent positive and negative functions: implications for development and disease Development, January 6, 1999; 126(14): 3205 - 3216. [Abstract] [PDF]