Notochord to endoderm signaling is required for pancreas development

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				N. Nekrep, J. Wang, T. Miyatsuka, and M. S. German Signals from the neural crest regulate beta-cell mass in the pancreas Development, June 15, 2008; 135(12): 2151 - 2160. [Abstract] [Full Text] [PDF]

				N. Shiraki, T. Yoshida, K. Araki, A. Umezawa, Y. Higuchi, H. Goto, K. Kume, and S. Kume Guided Differentiation of Embryonic Stem Cells into Pdx1-Expressing Regional-Specific Definitive Endoderm Stem Cells, April 1, 2008; 26(4): 874 - 885. [Abstract] [Full Text] [PDF]

				M. Kodama, F. Takeshita, S. Kanegasaki, T. Ochiya, and G. Quinn Pancreatic Endocrine and Exocrine Cell Ontogeny From Renal Capsule transplanted Embryonic Stem Cells in Streptozocin-injured Mice J. Histochem. Cytochem., January 1, 2008; 56(1): 33 - 44. [Abstract] [Full Text] [PDF]

				I. Manfroid, F. Delporte, A. Baudhuin, P. Motte, C. J. Neumann, M. L. Voz, J. A. Martial, and B. Peers Reciprocal endoderm-mesoderm interactions mediated by fgf24 and fgf10 govern pancreas development Development, November 15, 2007; 134(22): 4011 - 4021. [Abstract] [Full Text] [PDF]

				M. C. Jorgensen, J. Ahnfelt-Ronne, J. Hald, O. D. Madsen, P. Serup, and J. Hecksher-Sorensen An Illustrated Review of Early Pancreas Development in the Mouse Endocr. Rev., October 1, 2007; 28(6): 685 - 705. [Abstract] [Full Text] [PDF]

				G. R. van den Brink Hedgehog Signaling in Development and Homeostasis of the Gastrointestinal Tract Physiol Rev, October 1, 2007; 87(4): 1343 - 1375. [Abstract] [Full Text] [PDF]

				J. Jiang, M. Au, K. Lu, A. Eshpeter, G. Korbutt, G. Fisk, and A. S. Majumdar Generation of Insulin-Producing Islet-Like Clusters from Human Embryonic Stem Cells Stem Cells, August 1, 2007; 25(8): 1940 - 1953. [Abstract] [Full Text] [PDF]

				T. Wendl, D. Adzic, J. J. Schoenebeck, S. Scholpp, M. Brand, D. Yelon, and K. B. Rohr Early developmental specification of the thyroid gland depends on han-expressing surrounding tissue and on FGF signals Development, August 1, 2007; 134(15): 2871 - 2879. [Abstract] [Full Text] [PDF]

				G. Guillemain, G. Filhoulaud, G. Da Silva-Xavier, G. A. Rutter, and R. Scharfmann Glucose Is Necessary for Embryonic Pancreatic Endocrine Cell Differentiation J. Biol. Chem., May 18, 2007; 282(20): 15228 - 15237. [Abstract] [Full Text] [PDF]

				M. Attali, V. Stetsyuk, A. Basmaciogullari, V. Aiello, M. A. Zanta-Boussif, B. Duvillie, and R. Scharfmann Control of {beta}-Cell Differentiation by the Pancreatic Mesenchyme Diabetes, May 1, 2007; 56(5): 1248 - 1258. [Abstract] [Full Text] [PDF]

				J. K. Mfopou, V. De Groote, X. Xu, H. Heimberg, and L. Bouwens Sonic Hedgehog and Other Soluble Factors from Differentiating Embryoid Bodies Inhibit Pancreas Development Stem Cells, May 1, 2007; 25(5): 1156 - 1165. [Abstract] [Full Text] [PDF]

				J. Gromada, I. Franklin, and C. B. Wollheim {alpha}-Cells of the Endocrine Pancreas: 35 Years of Research but the Enigma Remains Endocr. Rev., February 1, 2007; 28(1): 84 - 116. [Abstract] [Full Text] [PDF]

				L. C. Murtaugh Pancreas and beta-cell development: from the actual to the possible Development, February 1, 2007; 134(3): 427 - 438. [Abstract] [Full Text] [PDF]

				B. Duvillie, M. Attali, A. Bounacer, P. Ravassard, A. Basmaciogullari, and R. Scharfmann The Mesenchyme Controls the Timing of Pancreatic {beta}-Cell Differentiation Diabetes, March 1, 2006; 55(3): 582 - 589. [Abstract] [Full Text] [PDF]

				D. Stafford, R. J. White, M. D. Kinkel, A. Linville, T. F. Schilling, and V. E. Prince Retinoids signal directly to zebrafish endoderm to specify insulin-expressing {beta}-cells Development, March 1, 2006; 133(5): 949 - 956. [Abstract] [Full Text] [PDF]

				Y. Fujitani, S. Fujitani, D. F. Boyer, M. Gannon, Y. Kawaguchi, M. Ray, M. Shiota, R. W. Stein, M. A. Magnuson, and C. V.E. Wright Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation Genes & Dev., January 15, 2006; 20(2): 253 - 266. [Abstract] [Full Text] [PDF]

				R. H. Hruban, N. V. Adsay, J. Albores-Saavedra, M. R. Anver, A. V. Biankin, G. P. Boivin, E. E. Furth, T. Furukawa, A. Klein, D. S. Klimstra, et al. Pathology of Genetically Engineered Mouse Models of Pancreatic Exocrine Cancer: Consensus Report and Recommendations Cancer Res., January 1, 2006; 66(1): 95 - 106. [Abstract] [Full Text] [PDF]

				H. J. Kim, S. Sumanas, S. Palencia-Desai, Y. Dong, J.-N. Chen, and S. Lin Genetic Analysis of Early Endocrine Pancreas Formation in Zebrafish Mol. Endocrinol., January 1, 2006; 20(1): 194 - 203. [Abstract] [Full Text] [PDF]

				G. K.C. Brolen, N. Heins, J. Edsbagge, and H. Semb Signals From the Embryonic Mouse Pancreas Induce Differentiation of Human Embryonic Stem Cells Into Insulin-Producing {beta}-Cell-Like Cells Diabetes, October 1, 2005; 54(10): 2867 - 2874. [Abstract] [Full Text] [PDF]

				D. L. Stemple Structure and function of the notochord: an essential organ for chordate development Development, June 1, 2005; 132(11): 2503 - 2512. [Abstract] [Full Text] [PDF]

				N. Shiraki, C.-J. Lai, Y. Hishikari, and S. Kume TGF-{beta} signaling potentiates differentiation of embryonic stem cells to Pdx-1 expressing endodermal cells Genes Cells, June 1, 2005; 10(6): 503 - 516. [Abstract] [Full Text] [PDF]

				J. F. Habener, D. M. Kemp, and M. K. Thomas Minireview: Transcriptional Regulation in Pancreatic Development Endocrinology, March 1, 2005; 146(3): 1025 - 1034. [Abstract] [Full Text] [PDF]

				C. Haumaitre, E. Barbacci, M. Jenny, M. O. Ott, G. Gradwohl, and S. Cereghini Lack of TCF2/vHNF1 in mice leads to pancreas agenesis PNAS, February 1, 2005; 102(5): 1490 - 1495. [Abstract] [Full Text] [PDF]

				H. T. Ku, N. Zhang, A. Kubo, R. O'Connor, M. Mao, G. Keller, and J. S. Bromberg Committing Embryonic Stem Cells to Early Endocrine Pancreas In Vitro Stem Cells, December 1, 2004; 22(7): 1205 - 1217. [Abstract] [Full Text] [PDF]

				Y. Choi, M. Ta, F. Atouf, and N. Lumelsky Adult Pancreas Generates Multipotent Stem Cells and Pancreatic and Nonpancreatic Progeny Stem Cells, November 1, 2004; 22(6): 1070 - 1084. [Abstract] [Full Text] [PDF]

				K. Gerrish, J. C. Van Velkinburgh, and R. Stein Conserved Transcriptional Regulatory Domains of the pdx-1 Gene Mol. Endocrinol., March 1, 2004; 18(3): 533 - 548. [Abstract] [Full Text] [PDF]

				H. Yoshitomi and K. S. Zaret Endothelial cell interactions initiate dorsal pancreas development by selectively inducing the transcription factor Ptf1a Development, February 15, 2004; 131(4): 807 - 817. [Abstract] [Full Text] [PDF]

				S. S. Tulachan, R. Doi, Y. Kawaguchi, S. Tsuji, S. Nakajima, T. Masui, M. Koizumi, E. Toyoda, T. Mori, D. Ito, et al. All-Trans Retinoic Acid Induces Differentiation of Ducts and Endocrine Cells by Mesenchymal/Epithelial Interactions in Embryonic Pancreas Diabetes, January 1, 2003; 52(1): 76 - 84. [Abstract] [Full Text] [PDF]

				C. S. Lee, N. J. Sund, M. Z. Vatamaniuk, F. M. Matschinsky, D. A. Stoffers, and K. H. Kaestner Foxa2 Controls Pdx1 Gene Expression in Pancreatic {beta}-Cells In Vivo Diabetes, August 1, 2002; 51(8): 2546 - 2551. [Abstract] [Full Text] [PDF]

				A. Bhushan, N. Itoh, S. Kato, J. P. Thiery, P. Czernichow, S. Bellusci, and R. Scharfmann Fgf10 is essential for maintaining the proliferative capacity of epithelial progenitor cells during early pancreatic organogenesis Development, December 15, 2001; 128(24): 5109 - 5117. [Abstract] [Full Text] [PDF]