Novel regulatory interactions revealed by studies of murine limb pattern in Wnt-7a and En-1 mutants

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Bhanot, P., Brink, M., Samos, C. H., Hsieh, J. C., Wang, Y., Macke, J. P., Andrew, D., Nathans, J. and Nusse, R (1996). A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382, 225-230.[Medline]

Chiang, C., Litingtung, Y., Lee, E., Young, K. E., Corden, J. L., Westphal, H. and Beachy, P. A (1996). Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383, 407-413.[Medline]

Cohen, B., McGuffin, M. E., Pfeifle, C., Segal, D. and Cohen, S. M (1992). apterous , a gene required for imaginal disc development in Drosophila encodes a member of the LIM family of developmental regulatory proteins. Genes Dev 6, 715-729.[Abstract/Free Full Text]

Crossley, P. H. and Martin, G. R (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.[Abstract]

Danielian, P. S. and McMahon, A. P (1996). Engrailed-1 as a target of the Wnt-1 signalling pathway in vertebrate midbrain development. Nature 383, 332-334.[Medline]

Dealy, C. N., Roth, A., Ferrari, D., Brown, A. M. C. and Kosher, R. A (1993). Wnt-5a and Wnt-7a are expressed in the developing chick limb bud in a manner suggesting roles in pattern formation along the proximodistal and dorsoventral axes. Mech. Dev 43, 175-186.[Medline]

Diaz-Benjumea, F. J. and Cohen, S. M (1993). Interaction between dorsal and ventral cells in the imaginal disc directs wing development in Drosophila. Cell 75, 741-752.[Medline]

Echelard, Y., Epstein, D. J., St-Jacques, B., Shen, L., Mohler, J., McMahon, J. A. and McMahon, A. P (1993). Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell 75, 1417-1430.[Medline]

Gavin, B., McMahon, J. and McMahon, A. P (1990). Expression of multiple novel int-1 / wnt-1 -related genes suggests a major role for the wnt-1 family of putative signaling molecules during fetal mouse development. Genes Dev 4, 2319-2332.[Abstract/Free Full Text]

Geduspan, J. S. and MacCabe, J. A (1987). The ectodermal control ofmesodermal patterns of differentiation in the developing chick wing. Dev. Biol 124, 398-408.[Medline]

Irvine, K. D. and Wieschaus, E (1994). fringe , a boundary-specific signaling molecule, mediates interactions between dorsal and ventral cells during Drosophila wing development. Cell 79, 595-606.[Medline]

Johnson, R. L., Riddle, R. D. and Tabin, C. J (1994). Mechanisms of limb patterning. Curr. Opin. Gen. Dev 4, 535-542.[Medline]

Johnston, S. H., Rauskolb, C., Wilson, R., Prabhakaran, B., Irvine, K. D. and Vogt, T. F (1997). A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. Development 124, 2245-2254.[Abstract]

Kim, J., Irvine, K. D. and Carroll, S. B (1995). Cell recognition, signal induction, and symmetrical gene activation at the D-V boundary of the developing Drosophila wing. Cell 82, 795-802.[Medline]

Knecht, A. K., Good, P. J., Dawid, I. B. and Harland, R. M (1995). D-V patterning and differentiation of noggin-induced neural tissue in the absence of mesoderm. Development 121, 1927-1936.[Abstract]

Laufer, E., Dahn, R., Orozco, O. E., Yeo, C.-Y., Pisenti, J., Henrique, D., Abbott, U. K., Fallon, J. F. and Tabin, C (1997). Expression of Radical fringe in limb-bud ectoderm regulates apical ectodermal ridge formation. Nature 386, 366-373.[Medline]

Laufer, E., Nelson, C. E., Johnson, R. L., Morgan, B. A. and Tabin, C (1994). Sonic hedgehog and Fgf-4 act through a signaling cascade and feedback loop to integrate growth and patterning of the developing limb bud. Cell 79, 993-1003.[Medline]

Logan, C., Hornbruch, A., Campbell, I. and Lumsden, A (1997). The role of Engrailed in establishing the dorsoventral axis of the chick limb. Development 124, 2317-2324.[Abstract]

Loomis, C. A., Harris, E., Michaud, J., Wurst, W., Hanks, M. and Joyner, A. L (1996). The mouse Engrailed-1 gene and ventral limb patterning. Nature 382, 360-363.[Medline]

Lyons, K. M., Pelton, R. W. and Hogan, B. L (1990). Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development 109, 833-844.[Abstract/Free Full Text]

MacCabe, J. A., Errick, J. and Saunders, Jr., J. W (1974). Ectodermal control of the dorsoventral axis in the leg bud of the chick embryo. Dev. Biol 39, 69-82.[Medline]

Michaud, J. L., Lapointe, F. and Le Douarin, N. M (1997). The dorsoventral polarity of the presumptive limb is determined by signals produced by the somites and by the lateral somatopleure. Development 124, 1453-1463.[Abstract]

Niswander, L., Jeffrey, S., Martin, G. R. and Tickle, C (1994). A positive feedback loop coordinates growth and patterning in the vertebrate limb. Nature 371, 609-612.[Medline]

Parr, B. A. and McMahon, A. P (1995). Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374, 631-640.

Parr, B. A., Shea, M. J., Vassileva, G. and McMahon, A. P (1993). Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119, 247-261.[Abstract]

Riddle, R. D., Ensini, M., Nelson, C., Tsuchida, T., Jessell, T. M. and Tabin, C (1995). Induction ofthe LIM homeobox gene Lmx1 by WNT7a establishes dorsoventral pattern in the vertebrate limb. Cell 83, 631-640.[Medline]

Riddle, R. D., Johnson, R. L., Laufer, E. and Tabin, C (1993). Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75, 1401-1416.[Medline]

Rodriguez-Esteban, C., Schwabe, J. W. R., De La Pena, J., Foys, B., Eshelman, B. and Izipsua Belmonte, J. C (1997). Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb. Nature 386, 360-366.[Medline]

Saunders Jr., J. W (1948). The proximo-distal sequence of origin of the parts of the chick wing and the role of the ectoderm. J. Exp. Zool 108, 363-403.[Medline]

Saunders Jr., J. W., Cairns, J. M. and Gasseling, M. T (1957). The role of the apical ectodermal ridge of ectoderm in the differentiation of the morphological structure of and inductive specificity of limb parts of the chick. J. Morphol 101, 57-88.

Summerbell, D (1974). A quantitative analysis of the effect of excision of the AER from the chick limb-bud. J. Embryol. Exp. Morphol 32, 651-660.[Medline]

Tickle, C (1995). Vertebrate limb development. Curr. Opin. Gen. Dev 5, 478-484.[Medline]

Tickle, C., Summerbell, D. and Wolpert, L (1975). Positional signaling and specification of digits in chick limb morphogenesis. Nature 254, 199-202.[Medline]

Travis, A., Amsterdam, A., Belanger, C. and Grosschedl, R (1991). LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function. Genes Dev 5, 880-894.[Abstract/Free Full Text]

Vogel, A., Rodriguez, C., Warnken, W. and Izpisua Belmonte, J. C (1995). Dorsal cell fate specified by chick Lmx1 during vertebrate limb development. Nature 378, 716-720.[Medline]

Vogel, A. and Tickle, C (1993). FGF-4 maintains polarizing activity of posterior limb bud cells in vivo and in vitro. Development 119, 199-206.[Abstract]

Wang, J. and Shackleford, G. M (1996). Murine Wnt10a and Wnt10b : cloning and expression in developing limbs, face and skin of embryos and in adults. Oncogene 13, 1537-1544.[Medline]

Wang, Y., Macke, J. P., Abella, B. S., Andreasson, K., Worley, P., Gilbert, D. J., Copeland, N. G., Jenkins, N. A. and Nathans, J (1996). A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. J. Biol. Chem 271, 4468-4476.[Abstract/Free Full Text]

Williams, J. A., Paddock, S. W. and Carroll, S. B (1993). Pattern formation in a secondary field: a hierarchy of regulatory genes subdivides thedeveloping Drosophila wing disc into discrete subregions. Development 117, 571-584.[Abstract]

Williams, J. A., Paddock, S. W., Vorwerk, K. and Carroll, S. B (1994). Organization of wing formation and induction of a wing-patterning gene at the dorsal/ventral compartment boundary. Nature 368, 299-305.[Medline]

Wurst, W., Auerbach, A. B. and Joyner, A. L (1994). Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum. Development 120, 2065-2075.[Abstract]

Yang, Y. and Niswander, L (1995). Interaction between the signaling molecules WNT-7A and SHH during vertebrate limb development: dorsal signals regulate anteroposterior patterning. Cell 80, 939-947.[Medline]

Zhou, P., Byrne, C., Jacobs, J. and Fuchs, E (1995). Lymphoid enhancer factor 1 directs hair follicle patterning and epithelial cell fate. Genes Dev 9, 700-713.[Abstract/Free Full Text]

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				R. A. Kimmel, D. H. Turnbull, V. Blanquet, W. Wurst, C. A. Loomis, and A. L. Joyner Two lineage boundaries coordinate vertebrate apical ectodermal ridge formation Genes & Dev., June 1, 2000; 14(11): 1377 - 1389. [Abstract] [Full Text]

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				S. D. Dreyer, R. Morello, M. S. German, B. Zabel, A. Winterpacht, G. P. Lunstrum, W. A. Horton, K. C. Oberg, and B. Lee LMX1B transactivation and expression in nail-patella syndrome Hum. Mol. Genet., April 12, 2000; 9(7): 1067 - 1074. [Abstract] [Full Text] [PDF]

				J. Galceran, I. Fariñas, M. J. Depew, H. Clevers, and R. Grosschedl Wnt3a-/--like phenotype and limb deficiency in Lef1-/-Tcf1-/- mice Genes & Dev., March 15, 1999; 13(6): 709 - 717. [Abstract] [Full Text]

				A. Tucker, A Al Khamis, C. Ferguson, I Bach, M. Rosenfeld, and P. Sharpe Conserved regulation of mesenchymal gene expression by Fgf-8 in face and limb development Development, January 1, 1999; 126(2): 221 - 228. [Abstract] [PDF]

				G. R. Martin The roles of FGFs in the early development of vertebrate�limbs Genes & Dev., June 1, 1998; 12(11): 1571 - 1586. [Full Text]

				M. Hanks, C. Loomis, E Harris, C. Tong, L Anson-Cartwright, A Auerbach, and A Joyner Drosophila engrailed can substitute for mouse Engrailed1 function in mid-hindbrain, but not limb development Development, January 11, 1998; 125(22): 4521 - 4530. [Abstract] [PDF]

				C Rodriguez-Esteban, J. Schwabe, J. Pena, D. Rincon-Limas, J Magallon, J Botas, and J. Belmonte Lhx2, a vertebrate homologue of apterous, regulates vertebrate limb outgrowth Development, January 10, 1998; 125(20): 3925 - 3934. [Abstract] [PDF]

				Y Yang, P Guillot, Y Boyd, M. Lyon, and A. McMahon Evidence that preaxial polydactyly in the Doublefoot mutant is due to ectopic Indian Hedgehog signaling Development, January 8, 1998; 125(16): 3123 - 3132. [Abstract] [PDF]

				C Miller and D. Sassoon Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract Development, January 8, 1998; 125(16): 3201 - 3211. [Abstract] [PDF]

				C. Loomis, R. Kimmel, C. Tong, J Michaud, and A. Joyner Analysis of the genetic pathway leading to formation of ectopic apical ectodermal ridges in mouse Engrailed-1 mutant limbs Development, January 3, 1998; 125(6): 1137 - 1148. [Abstract] [PDF]