Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors

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Artavanis-Tsakonas, S. Matsuno, K. and Fortini, M. E (1995). Notch signaling. Science 268, 225-232.[Abstract/Free Full Text]

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				M. Dorsett, B. Westlund, and T. Schedl METT-10, A Putative Methyltransferase, Inhibits Germ Cell Proliferative Fate in Caenorhabditis elegans Genetics, September 1, 2009; 183(1): 233 - 247. [Abstract] [Full Text] [PDF]

				M. McGovern, R. Voutev, J. Maciejowski, A. K. Corsi, and E. J. A. Hubbard A "latent niche" mechanism for tumor initiation PNAS, July 14, 2009; 106(28): 11617 - 11622. [Abstract] [Full Text] [PDF]

				A.-C. Tien, A. Rajan, K. L. Schulze, H. D. Ryoo, M. Acar, H. Steller, and H. J. Bellen Ero1L, a thiol oxidase, is required for Notch signaling through cysteine bridge formation of the Lin12-Notch repeats in Drosophila melanogaster J. Cell Biol., September 22, 2008; 182(6): 1113 - 1125. [Abstract] [Full Text] [PDF]

				J. Ouellet, S. Li, and R. Roy Notch signalling is required for both dauer maintenance and recovery in C. elegans Development, August 1, 2008; 135(15): 2583 - 2592. [Abstract] [Full Text] [PDF]

				H. Kagoshima, R. Nimmo, N. Saad, J. Tanaka, Y. Miwa, S. Mitani, Y. Kohara, and A. Woollard The C. elegans CBF{beta} homologue BRO-1 interacts with the Runx factor, RNT-1, to promote stem cell proliferation and self-renewal Development, November 1, 2007; 134(21): 3905 - 3915. [Abstract] [Full Text] [PDF]

				Y. Liu and E. M. Maine The Bro1-Domain Protein, EGO-2, Promotes Notch Signaling in Caenorhabditis elegans Genetics, August 1, 2007; 176(4): 2265 - 2277. [Abstract] [Full Text] [PDF]

				A. P. Weng, J. M. Millholland, Y. Yashiro-Ohtani, M. L. Arcangeli, A. Lau, C. Wai, C. del Bianco, C. G. Rodriguez, H. Sai, J. Tobias, et al. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma Genes & Dev., August 1, 2006; 20(15): 2096 - 2109. [Abstract] [Full Text] [PDF]

				P. Narbonne and R. Roy Inhibition of germline proliferation during C. elegans dauer development requires PTEN, LKB1 and AMPK signalling Development, February 15, 2006; 133(4): 611 - 619. [Abstract] [Full Text] [PDF]

				R. Ciosk, M. DePalma, and J. R. Priess Translational Regulators Maintain Totipotency in the Caenorhabditis elegans Germline Science, February 10, 2006; 311(5762): 851 - 853. [Abstract] [Full Text] [PDF]

				B. E. Thompson, D. S. Bernstein, J. L. Bachorik, A. G. Petcherski, M. Wickens, and J. Kimble Dose-dependent control of proliferation and sperm specification by FOG-1/CPEB Development, August 1, 2005; 132(15): 3471 - 3481. [Abstract] [Full Text] [PDF]

				V. E. Vought, M. Ohmachi, M.-H. Lee, and E. M. Maine EGO-1, a Putative RNA-Directed RNA Polymerase, Promotes Germline Proliferation in Parallel With GLP-1/Notch Signaling and Regulates the Spatial Organization of Nuclear Pore Complexes and Germline P Granules in Caenorhabditis elegans Genetics, July 1, 2005; 170(3): 1121 - 1132. [Abstract] [Full Text] [PDF]

				M. Vooijs, E. H. Schroeter, Y. Pan, M. Blandford, and R. Kopan Ectodomain Shedding and Intramembrane Cleavage of Mammalian Notch Proteins Are Not Regulated through Oligomerization J. Biol. Chem., December 3, 2004; 279(49): 50864 - 50873. [Abstract] [Full Text] [PDF]

				X. Tian, D. Hansen, T. Schedl, and J. B. Skeath Epsin potentiates Notch pathway activity in Drosophila and C. elegans Development, December 1, 2004; 131(23): 5807 - 5815. [Abstract] [Full Text] [PDF]

				C. Sanchez-Irizarry, A. C. Carpenter, A. P. Weng, W. S. Pear, J. C. Aster, and S. C. Blacklow Notch Subunit Heterodimerization and Prevention of Ligand-Independent Proteolytic Activation Depend, Respectively, on a Novel Domain and the LNR Repeats Mol. Cell. Biol., November 1, 2004; 24(21): 9265 - 9273. [Abstract] [Full Text] [PDF]

				A. P. Weng, A. A. Ferrando, W. Lee, J. P. Morris IV, L. B. Silverman, C. Sanchez-Irizarry, S. C. Blacklow, A. T. Look, and J. C. Aster Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia Science, October 8, 2004; 306(5694): 269 - 271. [Abstract] [Full Text] [PDF]

				E. M. Maine, D. Hansen, D. Springer, and V. E. Vought Caenorhabditis elegans atx-2 Promotes Germline Proliferation and the Oocyte Fate Genetics, October 1, 2004; 168(2): 817 - 830. [Abstract] [Full Text] [PDF]

				I. Cheung, M. Schertzer, A. Baross, A. M. Rose, P. M. Lansdorp, and D. M. Baird Strain-specific telomere length revealed by single telomere length analysis in Caenorhabditis elegans Nucleic Acids Res., June 24, 2004; 32(11): 3383 - 3391. [Abstract] [Full Text] [PDF]

				E. C. Lai Notch signaling: control of cell communication and cell fate Development, March 1, 2004; 131(5): 965 - 973. [Abstract] [Full Text] [PDF]

				D. Hansen, L. Wilson-Berry, T. Dang, and T. Schedl Control of the proliferation versus meiotic development decision in the C. elegans germline through regulation of GLD-1 protein accumulation Development, January 1, 2004; 131(1): 93 - 104. [Abstract] [Full Text] [PDF]

				G. F. Hoyne Notch signaling in the immune system J. Leukoc. Biol., December 1, 2003; 74(6): 971 - 981. [Abstract] [Full Text]

				B. Roberts, C. Clucas, and I. L. Johnstone Loss of SEC-23 in Caenorhabditis elegans Causes Defects in Oogenesis, Morphogenesis, and Extracellular Matrix Secretion Mol. Biol. Cell, November 1, 2003; 14(11): 4414 - 4426. [Abstract] [Full Text] [PDF]

				V. A. Marin and T. C. Evans Translational repression of a C. elegans Notch mRNA by the STAR/KH domain protein GLD-1 Development, June 15, 2003; 130(12): 2623 - 2632. [Abstract] [Full Text] [PDF]

				R. Gross-Hardt and T. Laux Stem cell regulation in the shoot meristem J. Cell Sci., May 1, 2003; 116(9): 1659 - 1666. [Abstract] [Full Text] [PDF]

				S. I. Tazuke, C. Schulz, L. Gilboa, M. Fogarty, A. P. Mahowald, A. Guichet, A. Ephrussi, C. G. Wood, R. Lehmann, and M. T. Fuller A germline-specific gap junction protein required for survival of differentiating early germ cells Development, March 7, 2003; 129(10): 2529 - 2539. [Abstract] [Full Text] [PDF]

				A. P. Weng, Y. Nam, M. S. Wolfe, W. S. Pear, J. D. Griffin, S. C. Blacklow, and J. C. Aster Growth Suppression of Pre-T Acute Lymphoblastic Leukemia Cells by Inhibition of Notch Signaling Mol. Cell. Biol., January 15, 2003; 23(2): 655 - 664. [Abstract] [Full Text] [PDF]

				M. P. Colaiacovo, G. M. Stanfield, K. C. Reddy, V. Reinke, S. K. Kim, and A. M. Villeneuve A Targeted RNAi Screen for Genes Involved in Chromosome Morphogenesis and Nuclear Organization in the Caenorhabditis elegans Germline Genetics, September 1, 2002; 162(1): 113 - 128. [Abstract] [Full Text] [PDF]

				J. J. Chern and K.-W. Choi Lobe mediates Notch signaling to control domain-specific growth in the Drosophila eye disc Development, September 1, 2002; 129(17): 4005 - 4013. [Abstract] [Full Text] [PDF]

				A. Lukaszewicz, P. Savatier, V. Cortay, H. Kennedy, and C. Dehay Contrasting Effects of Basic Fibroblast Growth Factor and Neurotrophin 3 on Cell Cycle Kinetics of Mouse Cortical Stem Cells J. Neurosci., August 1, 2002; 22(15): 6610 - 6622. [Abstract] [Full Text] [PDF]

				N. Arantes-Oliveira, J. Apfeld, A. Dillin, and C. Kenyon Regulation of Life-Span by Germ-Line Stem Cells in Caenorhabditis elegans Science, January 18, 2002; 295(5554): 502 - 505. [Abstract] [Full Text] [PDF]

				C. Schulz, C. G. Wood, D. L. Jones, S. I. Tazuke, and M. T. Fuller Signaling from germ cells mediated by the rhomboid homolog stet organizes encapsulation by somatic support cells Development, January 10, 2002; 129(19): 4523 - 4534. [Abstract] [Full Text] [PDF]