Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli

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Abboud, H. E., Grandaliano, G., Pinzani, M., Knauss, T., Pierce, G. F. and Jaffer, F (1994). Actions of platelet-derived growth factor isoforms in mesangial cells. J. Cell Physiol 158, 140-50.[Medline]

Abrahamson, D. R (1994). Glomerulogenesis in the developing kidney. Semin. Nephrol 11, 375-389.

Alpers, C. E., Seifert, R. A., Hudkins, K. L., Johnson, R. J. and Bowen-Pope, D. F (1992). Developmental patterns of PDGF B-chain, PDGF receptor and a-actin expression in human glomerulogenesis. Kidney Int 42, 390-399.[Medline]

Alpers, C. E., Seifert, R. A., Hudkins, K. L., Johnson, R. J. and Bowen-Pope, D. F (1993). PDGF-receptor localizes to mesangial, parietal epithelial and interstitial cells in human and primate kidneys. Kidney Int 43, 286-294.[Medline]

Barnes, J. L. and Hevey, K. A (1990). Glomerular mesangial cell migration in response to platelet-derived growth factor. Lab. Invest 62, 379-382.[Medline]

Betsholtz, C. and Raines, E (1997). Platelet-derived growth factor: A key regulator of connective tissue cells in embryogenesis and pathogenesis. Kidney Int 51, 1361-1369.[Medline]

H., Pekna, M., Hellstr\232m, M., Gebre-Medhin, S., Schalling, M., Nilsson, M., Kurland, S., T\232rnell, J., Heath, J. K. and Betsholtz, C (1996). PDGF-A signaling is a critical event in lung alveolar myofibroblast development and alveogenesis. Cell 85, 863-873.[Medline]

Breier, G., Albrecht, U., Sterrer, S. and Risau, W (1992). Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development 114, 521-532.[Abstract]

Doi, T., Vlassara, H., Kirstein, M., Yamada, Y., Striker, G. E. and Striker, L. J (1992). Receptor-specific increase in extracellular matrix production in mouse mesangial cells by advanced glycosylation end products is mediated via platelet-derived growth factor. Proc. Nat. Acad. Sci. USA 89, 2873-2877.[Abstract/Free Full Text]

Dudley, A. T., Lyons, K. M. and Robertson, E. J (1995). A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev 9, 2795-2807.[Abstract/Free Full Text]

Ekblom, P (1981). Formation of basement membranes in the embryonic kidney: An immunohistochemical study. J. Cell. Biol 91, 1-10.[Abstract/Free Full Text]

Fellstr\232m, B., Klareskog, L., Heldin, C.-H., Larsson, E., R\232nnstrand, L., Terracio, L., Tufveson, G., Wahlberg, J. and Rubin, K (1989). Platelet-derived growth factor receptors in the kidney \320 upregulated expression in inflammation. Kidney Int 36, 1099-1102.[Medline]

Floege, J., Topley, N., Hoppe, J., Barrett, T. B. and Resch, K (1991). Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: Modulation and/or suppression by inflammatory cytokines. Clin. Exp. Immunol 86, 334-341.[Medline]

Floege, J., Burns, M. W., Alpers, C. E., Yoshimura, A., Pritzl, P., Gordon, K., Seifert, R. A., Bowen, P. D., Couser, W. G. and Johnson, R. J (1992). Glomerular cell proliferation and PDGF expression precede glomerulosclerosis in the remnant kidney model. Kidney Int 41, 297-309.[Medline]

Grobstein, C (1955). Induction interaction in the development of the mouse metanephros. J. Exp. Zool 130, 319-340.

Hugo, C., Shankland, S. J., Bowen-Pope, D. F., Couser, W. G. and Johnson, R. J (1997). Extraglomerular origin of the mesangial cells after injury. A new role of the juxtaglomerular apparatus. J. Clin. Invest 100, 786-794.[Medline]

Hyink, D. P., Tucker, D. C., St John, P. L., Leardkamolkarn, V., Accavitti, M. A., Abrass, C. K. and Abrahamson, D. R (1996). Endogenous origin of glomerular endothelial and mesangial cells in grafts of embryonic kidneys. Am. J. Phys 270, 886-99.

Iida, H., Seifert, R., Alpers, C. E., Gronwald, R. G. K., Phillips, P. E., Pritlz, P., Gordon, K., Gown, A. M., Ross, R., Bowen-Pope, D. F. and Johnson, R. J (1991). Platelet-derived growth factor (PDGF) and PDGF receptors are induced in mesangial proliferative nephritis in the rat. Proc. Nat. Acad. Sci. USA 88, 6560-6564.[Abstract/Free Full Text]

Kispert, A., Vainio, S., Shen, L., Rowitch, D. R. and MacMahon, A. P (1996). Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development 122, 3627-3637.[Abstract]

Korhonen, J., Lahtinen, I., Halmekyt\232, M., Alhonen, L., J\212nne, J., Dumont, D. and Alitalo, K (1995). Endothelial-specific gene expression directed by the tie gene promoter in vivo. Blood 5, 1828-1835.

Leveen, P., Pekny, M., Gebre-Medhin, S., Swolin, B., Larsson, E. and Betsholtz, C (1994). Mice deficient for PDGF B show renal, cardiovascular and hematological abnormalities. Genes Dev 8, 1875-1887.[Abstract/Free Full Text]

Lindahl, P., Johansson, B., Leveen, P. and Betsholtz, C (1997). Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 277, 242-245.[Abstract/Free Full Text]

Lindahl, P., Karlsson, L., Hellstr\232m, M., Gebre-Medhin, S., Willetts, K., Heath, J. K. and Betsholtz, C (1997). Alveogenesis failure in PDGF-A deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development 124, 3943-3953.[Abstract]

Luo, G., Hofmann, C., Bronckers, A. L. J. J., Sohocki, M., Bradley, A. and Karsenty, G (1995). BMP-7 is an inducer of nephrogenesis and is also required for eye development and skeletal patterning. Genes Dev 9, 2808-2820.[Abstract/Free Full Text]

MacGregor, G. R., Zambrowicz, B. Z. and Soriano, P (1995). Tissue non-specific alkaline phosphatase is expressed in both embryonic and extraembryonic lineages during mouse embryognesis but is not required for migration of primordial germ cells. Development 121, 1487-1496.[Abstract]

Madri, J. A. and Marx, M (1992). Matrix composition, organization and soluble factors: Modulators of microvascular cell differentiation in vitro. Kidney Int 41, 560-565.[Medline]

Martinez-Hernandez, A. and Amenta, P. S (1983). The basement membrane in pathology. Lab. Invest 48, 656-677.[Medline]

Mene, P., Abboud, H. E., Dubyak, G. R., Scarpa, A. and Dunn, M. J (1987). Effects of PDGF on inositol phosphates, Ca2+and contraction of mesangial cells. Am. J. Physiol 253, 458-.

Michael, A. F., Keane, W. F., Raij, L., Vernier, R. L. and Mauer, S. M (1980). The glomerular mesangium. Kidney Int 17, 141-154.[Medline]

Michelakis, A. M., Yoshida, H., Menzie, J., Murakami, K. and Inagami, T (1974). A radioimmunoassay for the direct measurement of renin in mice and its application to submaxillary gland and kidney studies. Endocrinology 94, 1101-1105.[Medline]

Moore, M. W., Klein, R. D., Farinas, I., Sauer, H., Armanini, M., Phillips, H., Reichardt, L. F., Ryan, A. M.-J., Carver-Moore, K. and Rosenthal, A (1996). Renal and neuronal abnormalities in mice lacking GDNF. Nature 382, 76-79.[Medline]

Mortensen, R. M., Conner, D. A., Chao, S., Geisterfer-Lowrance, A. A. and Seidman, J. G (1992). Production of homozygous mutant ES cells with a single targeting construct. Mol. Cell. Biol 12, 2391-2395.[Abstract/Free Full Text]

Perantoni, A. O., Dove, L. F. and Karavanova, I (1995). Basic fibroblast growth factor can mediate the early inductive events in renal development. Proc. Nat. Acad. Sci. USA 92, 4696-4700.[Abstract/Free Full Text]

Pichel, J. G., Shen, L., Sheng, H. Z., Granholm, A. C., Drago, J., Grinberg, A., Lee, E. J., Huang, S. P., Saarma, M., Hoffer, B. J., Sariola, H. and Westphal, H (1996). Defects in enteric innervation and kidney development in mice lacking GDNF. Nature 382, 73-76.[Medline]

Puri, M. C., Rossant, J., Alitalo, K., Bernstein, A. and Partanen, J (1995). The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells. EMBO J 14, 5884-5891.[Medline]

S\207nchez, M. P., Silos-Santiago, I., Frisen, J., He, B., Lira, S. A. and Barbacid, M (1996). Renal agenesis and the absence of enteric neurons in mice lacking GDNF. Nature 382, 70-73.[Medline]

Santos, O. F. P., Baras, E. J. G., Yang, X.-M., Matsumoto, K., Nakamura, T., Park, M. and Nigam, S. K (1994). Involvement of hepatocyte growth factor in kidney development. Dev. Biol 163, 525-529.[Medline]

Sariola, H., Timpl, R., von der Mark, K., Mayne, R., Fitch, J. M., Linsenmayer, T. F. and Ekblom, P (1984). Dual origin of glomerular basement membrane. Dev. Biol 101, 86-96.[Medline]

Savill, J., Smith, J., Sarraf, C., Ren, Y., Abbott, F. and Rees, A (1992). Glomerular mesangial cells and inflammatory macrophages ingest neutrophils undergoing apoptosis. Kidney Int 42, 924-936.[Medline]

Schlondorff, D. and Mori, T (1990). Contributions of mesangial cells to glomerular immune functions. Klin. Wochenschr 68, 1138-1144.[Medline]

Schuchardt, A., D'Agati, V., Pachnis, V. and Costantini, F (1996). Renal agenesis and hypodysplasia in ret-k-mutant mice result from defects in ureteric bud development. Development 122, 1919-1929.[Abstract]

Shultz, P. J., DiCorleto, P. E., Silver, B. J. and Abboud, H. E (1988). Mesangial cells express PDGF mRNAs and proliferate in response to PDGF. Am. J. Physiol 255, 674-.

Silver, B. J., Jaffer, F. E. and Abboud, H. E (1989). Platelet-derived growth factor synthesis in mesangial cells: induction by multiple peptide mitogens. Proc. Nat. Acad. Sci. USA 86, 1056-1060.[Abstract/Free Full Text]

Soriano, P (1994). Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice. Genes Dev 8, 1888-1896.[Abstract/Free Full Text]

Stark, K., Vainio, S., Vassileva, G. and McMahon, A. P (1994). Epithelial transformation of the metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372, 679-683.[Medline]

Taugner, R., Hackenthal, E., Rix, E., Nobiling, R. and Poulsen, K (1982). Immunocytochemistry of the renin-angiotensin system: Renin, angiotensinogen, angiotensin I, angiotensin II and converting enzyme in the kidneys of mice, rats and tree shrews. Kidney Int 22, 33-.

Toyabe, S. and Iwanaga, T (1992). An ultrastructural study of proliferative nephritis induced experimentally by a monoclonal antibody against mesangial cells: replacement of mesangial cells by cells of the monocyte-macrophage system. Virchows Arch. B Cell Pathol. Incl. Mol. Pathol 61, 397-407.[Medline]

Woolf, A. S., Kolatsi-Joannou, M., Hardman, P. andermarcher, E., Moorby, C., Fine, L. G., Jat, P. S., Noble, M. D. and Gherardi, E (1995). Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephros. J. Cell Biol 128, 171-184.[Abstract/Free Full Text]

Zambrowicz, B. P., Imamoto, A., Fiering, S., Herzenberg, L. A., Kerr, W. G. and Soriano, P (1997). Disruption of overlapping transcripts in the ROSAgeo 26 gene trap strain leads to widespread expression of -galactosidase in mouse embryos and hematopoietic cells. Proc. Nat. Acad. Sci. USA 94, 3789-3794.[Abstract/Free Full Text]

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J. M. Ricono, M. Arar, G. G. Choudhury, and H. E. Abboud
Effect of platelet-derived growth factor isoforms in rat metanephric mesenchymal cells
Am J Physiol Renal Physiol, February 1, 2002; 282(2): F211 - F219.
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