Atm deficiency results in severe meiotic disruption as early as leptonema of prophase I

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Artuso, M., Esteve, A., Bresil, H., Vuillaume, M. and Hall, J (1995). The role of the Ataxia telangiectasia gene in the p53, WAF1/CIP1(p21)-and GADD45-mediated response to DNA damage produced by ionising radiation. Oncogene 11, 1427-1435.[Medline]

Baker, B. S. and Carpenter, A. T. C (1972). Genetic analysis of sex chromosomal meiotic mutants in Drosophila melanogaster. Genetics 90, 255-286.

Barlow, C., Hirotsune, S., Paylor, R., Liyanage, M., Eckhaus, M., Collins, F., Shiloh, Y., Crawley, J. N., Ried, T., Tagle, D. and Wynshaw-Boris, A (1996). Atm-deficient mice: a paradigm of ataxia telangiectasia. Cell 86, 159-171.[Medline]

Barlow, C., Liyanage, M., Moens, P. B., Deng, C.-X., Ried, T. and Wynshaw-Boris, A (1997). Partial rescue of the severe prophase I defects of Atm -deficient mice by p53 and p21 null alleles. Nature Genet 17, 462-466.[Medline]

Barlow, C., Brown, K. D., Deng, C.-X., Tagle, D. A. and Wynshaw-Boris, A (1997). Atm selectively regulates distinct p53-dependent cell cycle checkpoint and apoptotic pathways. Nature Genet 17, 453-456.[Medline]

Bellve, A. R (1993). Purification, culture and fractionation of spermatogenic cells. Meth. Enzymol 225, 84-113.[Medline]

Bishop, D., K,, Park, D., Xu, L. and Kleckner, N (1992). DMC1: a meiosis-specific yeast homolog of E.coli recA required for recombination, synaptonemal complex formation, and cell cycle progression. Cell 69, 439-456.[Medline]

Bishop, D. K (1994). RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis. Cell 79, 1081-1092.[Medline]

Boder, E (1975). Ataxia-telangiectasia: some historic, clinical and pathologic observations. Birth Defects 11, 255-270.

Carpenter, A. T. C (1979). Recombination nodules and synaptonemal complex in recombination-defective females of Drosophila melanogaster. Chromosoma 75, 259-292.[Medline]

Chen, G. and Lee, E. Y. H.-P (1996). The product of the ATM gene is a 370-kDa nuclear phosphoprotein. J. Biol. Chem 271, 33693-7.[Abstract/Free Full Text]

Dobson, M. J., Pearlman, R. E., Karaiskakis, A., Spyropoulos, B. and Moens, P. B (1994). Synaptonemal complex proteins: occurrence, epitope mapping and chromosome disjunction. J. Cell Sci 107, 2749-2760.[Abstract]

Dresser, M. E. and Moses, M. J (1979). Silver staining of synaptonemal complexes in surface spreads for light and electron microscopy. Exp. Cell Res 121, 416-419.[Medline]

Hari, K. L., Santerre, A., Sekelsky, J. J., McKim, K., Boyd, J. B. and Hawley, R. S (1995). The mei-41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell 82, 815-821.[Medline]

Kastan, M. B., Zhan, Q., el-Deiry, W. S., Carrier, F., Jacks, T., Walsh, W. V., Plunkett, B. S., Vogelstein, B. and Fornace, A. J., Jr (1992). A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell 71, 587-97.[Medline]

Kato, R. and Ogawa, H (1994). An essential gene, ESR1 , is required for mitotic growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae. Nucl. Acids Res 22, 3104-3112.[Abstract/Free Full Text]

Keegan, K. S., Holtzman, D. A., Plug, A. W., Christenson, E. R., Brainerd, E. E., Flaggs, G., Bentley, N. J., Taylor, E. M., Meyn, M. S., Moss, S. B., Carr, A. M., Ashley, T. and Hoekstra, M. F (1996). The Atr and Atm protein kinases associate with different sites along meiotically pairing chromosomes. Genes Dev 10, 2423-2437.[Abstract/Free Full Text]

Koehler, K. E., Hawley, R. S., Sherman, S. and Hassold, T (1996). Recombination and non-disjunction in humans and flies. Human Mol. Genet 5, 1495-1504.[Abstract]

Lakin, N. D., Weber, P., Stankovic, T., Rottinghaus, S. T., Taylor, A. M. and Jackson, S. P (1996). Analysis of the ATM protein in wild-type and ataxia telangiectasia cells. Oncogene 13, 2707-16.[Medline]

Lin, W.-C. and Desiderio, S (1995). V(D)J recombination and the cell cycle. Immunol. Today 16, 279-289.[Medline]

Lydall, D., Nikolsky, Y., Bishop, D. K. and Weinert, T (1996). A meiotic recombination checkpoint controlled by mitotic checkpoint genes. Nature 383, 840-843.[Medline]

Meyn, M. S (1995). Ataxia-telangiectasia and cellular responses to DNA damage. Cancer Res 55, 5991-6001.[Abstract/Free Full Text]

Moens, P. B., Chen, D. J., Shen, Z., Kolas, N., Tarsounas, M., Heng, H. H. Q. and Spyropoulos, B (1997). Rad51 immunocytology in rat and mouse spermatocytes and oocytes. Chromosoma 105, 207-215.

Pittman, D. L., Cobb, J., Schimenti, K. J., Wilson, L. A., Cooper, D. M., Brignull, E., Handel, M. A. and Schimenti, J. C (1998). Meiotic prophase arrest with failure of chromosome synapsis in mice deficient for Dmc1, a germline-specific RecA homolog. Mol. Cell 1, 697-705.

Plug, A. W., Peters, A., Xu., Y., Keegan, K. S., Hoekstra, M. F., Baltimore, D., deBoer, P. and Ashley, T (1997). ATM and RPA in meiotic chromosome synapsis and recombination. Nat. Genet 17, 457-461.[Medline]

Roeder, G. S (1997). Meiotic chromosomes: it takes two to tango. Genes Dev 92, 10450-10456.

Shiloh, Y (1995). Ataxia-telangiectasia: closer to unraveling the mystery. Eur. J. Hum. Genet 3, 116-38.[Medline]

Weinert, T. A., Kiser, G. L. and Hartwell, L. H (1994). Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 8, 652-665.[Abstract/Free Full Text]

Xu, Y., Ashley, T., Brainerd, E. E., Bronson, R. T., Meyn, M. S. and Baltimore, D (1996). Targeted disruption of ATM leads to growth retardation, chromosomal fragmentation during meiosis, immune defects, and thymic lymphoma. Genes Dev 10, 2411-2422.[Abstract/Free Full Text]

Xu, Y. and Baltimore, D (1996). Dual roles of ATM in the cellular response to irradiation and in cell growth. Genes Dev 10, 2401-2410.[Abstract/Free Full Text]

Yoshida, K., Kondoh, G., Matsuda, Y., Habu, T., Nishimune, Y. and Morita, T (1998). The mouse RecA-like gene Dmc1 is required for homologous chromosome synapsis during meiosis. Mol. Cell 1, 707-718.

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				Y. Choi, D. J. Ballow, Y. Xin, and A. Rajkovic Lim Homeobox Gene, Lhx8, Is Essential for Mouse Oocyte Differentiation and Survival Biol Reprod, September 1, 2008; 79(3): 442 - 449. [Abstract] [Full Text] [PDF]

				H. Cartagena-Lirola, I. Guerini, N. Manfrini, G. Lucchini, and M. P. Longhese Role of the Saccharomyces cerevisiae Rad53 Checkpoint Kinase in Signaling Double-Strand Breaks during the Meiotic Cell Cycle Mol. Cell. Biol., July 15, 2008; 28(14): 4480 - 4493. [Abstract] [Full Text] [PDF]

				S. S. Palii, B. O. Van Emburgh, U. T. Sankpal, K. D. Brown, and K. D. Robertson DNA Methylation Inhibitor 5-Aza-2'-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B Mol. Cell. Biol., January 15, 2008; 28(2): 752 - 771. [Abstract] [Full Text] [PDF]

				A M Lobascio, F G Klinger, M L Scaldaferri, D Farini, and M De Felici Analysis of programmed cell death in mouse fetal oocytes Reproduction, August 1, 2007; 134(2): 241 - 252. [Abstract] [Full Text] [PDF]

				I. R. Matei, R. A. Gladdy, L. M. J. Nutter, A. Canty, C. J. Guidos, and J. S. Danska ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes Blood, March 1, 2007; 109(5): 1887 - 1896. [Abstract] [Full Text] [PDF]

				F. Dantzer, M. Mark, D. Quenet, H. Scherthan, A. Huber, B. Liebe, L. Monaco, A. Chicheportiche, P. Sassone-Corsi, G. de Murcia, et al. Poly(ADP-ribose) polymerase-2 contributes to the fidelity of male meiosis I and spermiogenesis PNAS, October 3, 2006; 103(40): 14854 - 14859. [Abstract] [Full Text] [PDF]

				K.R. Barnett, C. Schilling, C.R. Greenfeld, D. Tomic, and J.A. Flaws Ovarian follicle development and transgenic mouse models Hum. Reprod. Update, September 1, 2006; 12(5): 537 - 555. [Abstract] [Full Text] [PDF]

				N. Rasheed, X. Wang, Q.-T. Niu, J. Yeh, and B. Li Atm-deficient mice: an osteoporosis model with defective osteoblast differentiation and increased osteoclastogenesis Hum. Mol. Genet., June 15, 2006; 15(12): 1938 - 1948. [Abstract] [Full Text] [PDF]

				P. E. Cohen, S. E. Pollack, and J. W. Pollard Genetic Analysis of Chromosome Pairing, Recombination, and Cell Cycle Control during First Meiotic Prophase in Mammals Endocr. Rev., June 1, 2006; 27(4): 398 - 426. [Abstract] [Full Text] [PDF]

				M. A Morelli and P. E Cohen Not all germ cells are created equal: Aspects of sexual dimorphism in mammalian meiosis Reproduction, December 1, 2005; 130(6): 761 - 781. [Abstract] [Full Text] [PDF]

				S. Lu, K. C. Shen, Y. Wang, S.C. Brooks, and Y. A. Wang Impaired hepatocyte survival and liver regeneration in Atm-deficient mice Hum. Mol. Genet., October 15, 2005; 14(20): 3019 - 3025. [Abstract] [Full Text] [PDF]

				M. Barchi, S. Mahadevaiah, M. Di Giacomo, F. Baudat, D. G. de Rooij, P. S. Burgoyne, M. Jasin, and S. Keeney Surveillance of Different Recombination Defects in Mouse Spermatocytes Yields Distinct Responses despite Elimination at an Identical Developmental Stage Mol. Cell. Biol., August 15, 2005; 25(16): 7203 - 7215. [Abstract] [Full Text] [PDF]

				M. A. Bellani, P. J. Romanienko, D. A. Cairatti, and R. D. Camerini-Otero SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes J. Cell Sci., August 1, 2005; 118(15): 3233 - 3245. [Abstract] [Full Text] [PDF]

				A. Aguilar-Mahecha, B. F. Hales, and B. Robaire Effects of Acute and Chronic Cyclophosphamide Treatment on Meiotic Progression and the Induction of DNA Double-Strand Breaks in Rat Spermatocytes Biol Reprod, June 1, 2005; 72(6): 1297 - 1304. [Abstract] [Full Text] [PDF]

				D. G. Pankratz and S. L. Forsburg Meiotic S-Phase Damage Activates Recombination without Checkpoint Arrest Mol. Biol. Cell, April 1, 2005; 16(4): 1651 - 1660. [Abstract] [Full Text] [PDF]

				M. Di Giacomo, M. Barchi, F. Baudat, W. Edelmann, S. Keeney, and M. Jasin Distinct DNA-damage-dependent and -independent responses drive the loss of oocytes in recombination-defective mouse mutants PNAS, January 18, 2005; 102(3): 737 - 742. [Abstract] [Full Text] [PDF]

				G. Hamer, H. B. Kal, C. H. Westphal, T. Ashley, and D. G. de Rooij Ataxia Telangiectasia Mutated Expression and Activation in the Testis Biol Reprod, April 1, 2004; 70(4): 1206 - 1212. [Abstract] [Full Text] [PDF]

				D. Perera, L. Perez-Hidalgo, P. B. Moens, K. Reini, N. Lakin, J. E. Syvaoja, P. A. San-Segundo, and R. Freire TopBP1 and ATR Colocalization at Meiotic Chromosomes: Role of TopBP1/Cut5 in the Meiotic Recombination Checkpoint Mol. Biol. Cell, April 1, 2004; 15(4): 1568 - 1579. [Abstract] [Full Text] [PDF]

				L. Qi, M. A. Strong, B. O. Karim, M. Armanios, D. L. Huso, and C. W. Greider Short Telomeres and Ataxia-Telangiectasia Mutated Deficiency Cooperatively Increase Telomere Dysfunction and Suppress Tumorigenesis Cancer Res., December 1, 2003; 63(23): 8188 - 8196. [Abstract] [Full Text] [PDF]

				K. M. Hopkins, X. Wang, A. Berlin, H. Hang, H. M. Thaker, and H. B. Lieberman Expression of Mammalian Paralogues of HRAD9 and Mrad9 Checkpoint Control Genes in Normal and Cancerous Testicular Tissue Cancer Res., September 1, 2003; 63(17): 5291 - 5298. [Abstract] [Full Text] [PDF]

				X. Xu, O. Aprelikova, P. Moens, C.-X. Deng, and P. A. Furth Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice Development, May 1, 2003; 130(9): 2001 - 2012. [Abstract] [Full Text] [PDF]

				C. H. Spruck, M. P. de Miguel, A. P. L. Smith, A. Ryan, P. Stein, R. M. Schultz, A. J. Lincoln, P. J. Donovan, and S. I. Reed Requirement of Cks2 for the First Metaphase/Anaphase Transition of Mammalian Meiosis Science, April 25, 2003; 300(5619): 647 - 650. [Abstract] [Full Text] [PDF]

				G. Hamer, H. L. Roepers-Gajadien, A. van Duyn-Goedhart, I. S. Gademan, H. B. Kal, P. P.W. van Buul, T. Ashley, and D. G. de Rooij Function of DNA-Protein Kinase Catalytic Subunit During the Early Meiotic Prophase Without Ku70 and Ku86 Biol Reprod, March 1, 2003; 68(3): 717 - 721. [Abstract] [Full Text] [PDF]

				N. A. Eckardt ATM to the Rescue: Repairing DNA Damage PLANT CELL, January 1, 2003; 15(1): 1 - 3. [Full Text] [PDF]

				V. Garcia, H. Bruchet, D. Camescasse, F. Granier, D. Bouchez, and A. Tissier AtATM Is Essential for Meiosis and the Somatic Response to DNA Damage in Plants PLANT CELL, January 1, 2003; 15(1): 119 - 132. [Abstract] [Full Text] [PDF]

				D. Escalier, L. Eloy, and H.-J. Garchon Sex-Specific Gene Expression During Meiotic Prophase I: Xlr (X Linked, Lymphocyte Regulated), Not Its Male Homologue Xmr (Xlr Related, Meiosis Regulated), Is Expressed in Mouse Oocytes Biol Reprod, November 1, 2002; 67(5): 1646 - 1652. [Abstract] [Full Text] [PDF]

				T. M. Matikainen, T. Moriyama, Y. Morita, G. I. Perez, S. J. Korsmeyer, D. H. Sherr, and J. L. Tilly Ligand Activation of the Aromatic Hydrocarbon Receptor Transcription Factor Drives Bax-Dependent Apoptosis in Developing Fetal Ovarian Germ Cells Endocrinology, February 1, 2002; 143(2): 615 - 620. [Abstract] [Full Text] [PDF]

				H. Scherthan, M. Jerratsch, S. Dhar, Y. A. Wang, S. P. Goff, and T. K. Pandita Meiotic Telomere Distribution and Sertoli Cell Nuclear Architecture Are Altered in Atm- and Atm-p53-Deficient Mice Mol. Cell. Biol., October 15, 2000; 20(20): 7773 - 7783. [Abstract] [Full Text]

				M. Liyanage, Z. Weaver, C. Barlow, A. Coleman, D. G. Pankratz, S. Anderson, A. Wynshaw-Boris, and T. Ried Abnormal rearrangement within the alpha /delta T-cell receptor locus in lymphomas from Atm-deficient mice Blood, September 1, 2000; 96(5): 1940 - 1946. [Abstract] [Full Text] [PDF]

				M. Wilda, I. Demuth, P. Concannon, K. Sperling, and H. Hameister Expression pattern of the Nijmegen breakage syndrome gene, Nbs1, during murine development Hum. Mol. Genet., July 22, 2000; 9(12): 1739 - 1744. [Abstract] [Full Text] [PDF]