Visceral endoderm-restricted translation of Otx1 mediates recovery of Otx2 requirements for specification of anterior neural plate and normal gastrulation

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Acampora, D., Mazan, S., Lallemand, Y., Avantaggiato, V., Maury, M., Simeone, A. and Br\236let, P (1995). Forebrain and midbrain regions are deleted Otx2/ mutants due to a defective anterior neuroectoderm specification during gastrulation. Development 121, 3279-3290.[Abstract]

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				S. T. Waters and M. Lewandoski A threshold requirement for Gbx2 levels in hindbrain development. Development, May 1, 2006; 133(10): 1991 - 2000. [Abstract] [Full Text] [PDF]

				J. Y. H. Li, Z. Lao, and A. L. Joyner New regulatory interactions and cellular responses in the isthmic organizer region revealed by altering Gbx2 expression Development, April 15, 2005; 132(8): 1971 - 1981. [Abstract] [Full Text] [PDF]

				M. Rhinn, K. Lun, M. Luz, M. Werner, and M. Brand Positioning of the midbrain-hindbrain boundary organizer through global posteriorization of the neuroectoderm mediated by Wnt8 signaling Development, March 15, 2005; 132(6): 1261 - 1272. [Abstract] [Full Text] [PDF]

				D. Kurokawa, N. Takasaki, H. Kiyonari, R. Nakayama, C. Kimura-Yoshida, I. Matsuo, and S. Aizawa Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm Development, July 15, 2004; 131(14): 3307 - 3317. [Abstract] [Full Text] [PDF]

				E. Puelles, A. Annino, F. Tuorto, A. Usiello, D. Acampora, T. Czerny, C. Brodski, S.-L. Ang, W. Wurst, and A. Simeone Otx2 regulates the extent, identity and fate of neuronal progenitor domains in the ventral midbrain Development, May 1, 2004; 131(9): 2037 - 2048. [Abstract] [Full Text] [PDF]

				K. Shimozaki, K. Nakashima, H. Niwa, and T. Taga Involvement of Oct3/4 in the enhancement of neuronal differentiation of ES cells in neurogenesis-inducing cultures Development, June 1, 2003; 130(11): 2505 - 2512. [Abstract] [Full Text] [PDF]

				A. S. Viczian, R. Vignali, M. E. Zuber, G. Barsacchi, and W. A. Harris XOtx5b and XOtx2 regulate photoreceptor and bipolar fates in the Xenopus retina Development, April 1, 2003; 130(7): 1281 - 1294. [Abstract] [Full Text] [PDF]

				W. Chen, Y. Liang, W. Deng, K. Shimizu, A. M. Ashique, E. Li, and Y.-P. Li The zinc-finger protein CNBP is required for forebrain formation in the mouse Development, April 1, 2003; 130(7): 1367 - 1379. [Abstract] [Full Text] [PDF]

				T. Hide, J. Hatakeyama, C. Kimura-Yoshida, E Tian, N. Takeda, Y. Ushio, T. Shiroishi, S. Aizawa, and I. Matsuo Genetic modifiers of otocephalic phenotypes in Otx2 heterozygous mutant mice Development, March 11, 2003; 129(18): 4347 - 4357. [Abstract] [Full Text] [PDF]

				P. L. Pfeffer, B. Payer, G. Reim, M. P. di Magliano, and M. Busslinger The activation and maintenance of Pax2 expression at the mid-hindbrain boundary is controlled by separate enhancers Development, March 3, 2003; 129(2): 307 - 318. [Abstract] [Full Text] [PDF]

				M. Mukhopadhyay, A. Teufel, T. Yamashita, A. D. Agulnick, L. Chen, K. M. Downs, A. Schindler, A. Grinberg, S.-P. Huang, D. Dorward, et al. Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation Development, February 1, 2003; 130(3): 495 - 505. [Abstract] [Full Text] [PDF]

				A. Glavic, J. L. Gomez-Skarmeta, and R. Mayor The homeoprotein Xiro1 is required for midbrain-hindbrain boundary formation Development, January 4, 2002; 129(7): 1609 - 1621. [Abstract] [Full Text] [PDF]

				J. Y. H. Li and A. L. Joyner Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression Development, December 15, 2001; 128(24): 4979 - 4991. [Abstract] [Full Text] [PDF]

				J. P. Martinez-Barbera, M. Signore, P. P. Boyl, E. Puelles, D. Acampora, R. Gogoi, F. Schubert, A. Lumsden, and A. Simeone Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2 Development, December 1, 2001; 128(23): 4789 - 4800. [Abstract] [Full Text] [PDF]

				D. Acampora, P. P. Boyl, M. Signore, J. P. Martinez-Barbera, C. Ilengo, E. Puelles, A. Annino, H. Reichert, G. Corte, and A. Simeone OTD/OTX2 functional equivalence depends on 5' and 3' UTR-mediated control of Otx2 mRNA for nucleo-cytoplasmic export and epiblast-restricted translation Development, December 1, 2001; 128(23): 4801 - 4813. [Abstract] [Full Text] [PDF]

				A. Tallafu{beta}, T. P. Wilm, M. Crozatier, P. Pfeffer, M. Wassef, and L. Bally-Cuif The zebrafish buttonhead-like factor Bts1 is an early regulator of pax2.1 expression during mid-hindbrain development Development, October 15, 2001; 128(20): 4021 - 4034. [Abstract] [Full Text] [PDF]

				P. P. Boyl, M. Signore, D. Acampora, J. P. Martinez-Barbera, C. Ilengo, A. Annino, G. Corte, and A. Simeone Forebrain and midbrain development requires epiblast-restricted Otx2 translational control mediated by its 3' UTR Development, August 1, 2001; 128(15): 2989 - 3000. [Abstract] [Full Text] [PDF]

				A Perea-Gomez, K. Lawson, M Rhinn, L Zakin, P Brulet, S Mazan, and S. Ang Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo Development, January 3, 2001; 128(5): 753 - 765. [Abstract] [PDF]

				A Liu and A. Joyner EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region Development, January 1, 2001; 128(2): 181 - 191. [Abstract] [PDF]

				R. Cantos, L. K. Cole, D. Acampora, A. Simeone, and D. K. Wu Patterning of the mammalian cochlea PNAS, October 24, 2000; 97(22): 11707 - 11713. [Abstract] [Full Text] [PDF]

				J. Huelsken, R. Vogel, V. Brinkmann, B. Erdmann, C. Birchmeier, and W. Birchmeier Requirement for {beta}-Catenin in Anterior-Posterior Axis Formation in Mice J. Cell Biol., February 7, 2000; 148(3): 567 - 578. [Abstract] [Full Text] [PDF]

				A. Foley, I Skromne, and C. Stern Reconciling different models of forebrain induction and patterning: a dual role for the hypoblast Development, January 9, 2000; 127(17): 3839 - 3854. [Abstract] [PDF]

				J. Martinez Barbera, M Clements, P Thomas, T Rodriguez, D Meloy, D Kioussis, and R. Beddington The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation Development, January 6, 2000; 127(11): 2433 - 2445. [Abstract] [PDF]

				A Liu, K Losos, and A. Joyner FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate Development, January 11, 1999; 126(21): 4827 - 4838. [Abstract] [PDF]

				U Borello, M Coletta, S Tajbakhsh, L Leyns, E. De Robertis, M Buckingham, and G Cossu Transplacental delivery of the Wnt antagonist Frzb1 inhibits development of caudal paraxial mesoderm and skeletal myogenesis in mouse embryos Development, January 10, 1999; 126(19): 4247 - 4255. [Abstract] [PDF]

				H Morsli, F Tuorto, D Choo, M. Postiglione, A Simeone, and D. Wu Otx1 and Otx2 activities are required for the normal development of the mouse inner ear Development, January 6, 1999; 126(11): 2335 - 2343. [Abstract] [PDF]

				M Hidalgo-Sanchez, A Simeone, and R. Alvarado-Mallart Fgf8 and Gbx2 induction concomitant with Otx2 repression is correlated with midbrain-hindbrain fate of caudal prosencephalon Development, January 6, 1999; 126(14): 3191 - 3203. [Abstract] [PDF]

				D Acampora, V Avantaggiato, F Tuorto, P Barone, M Perera, D Choo, D Wu, G Corte, and A Simeone Differential transcriptional control as the major molecular event in generating Otx1-/- and Otx2-/- divergent phenotypes Development, January 4, 1999; 126(7): 1417 - 1426. [Abstract] [PDF]