The Drosophila Medea gene is required downstream of dpp and encodes a functional homolog of human Smad4

QUICK SEARCH:

[advanced]

	Author:		Keyword(s):

Home Help Feedback Subscriptions Archive Search Table of Contents

This Article

	Summary
	Full Text (PDF)
	Alert me when this article is cited
	Alert me if a correction is posted

Services

	Email this article to a friend
	Similar articles in this journal
	Similar articles in PubMed
	Alert me to new issues of the journal
	Download to citation manager


Citing Articles

	Citing Articles via HighWire
	Citing Articles via Google Scholar

Google Scholar

	Articles by Hudson, J. B.
	Articles by Ferguson, E. L.
	Search for Related Content

PubMed

	PubMed Citation
	Articles by Hudson, J. B.
	Articles by Ferguson, E. L.


Social Bookmarking

	What's this?

Affolter, M., Nellen, D., Nussbaumer, U. and Basler, K (1994). Multiple requirements for the receptor serine/threonine kinase thick veins reveal novel functions of TGF beta homologs during Drosophila embryogenesis. Development 120, 3105-3117.[Abstract]

Arora, K., Dai, H., Kazuko, S. G., Jamal, J., O'Connor, M. B., Letsou, A. and Warrior, R (1995). The Drosophila schnurri gene acts in the Dpp/TGF beta signaling pathway and encodes a transcription factor homologous to the human MBP family. Cell 81, 781-790.[Medline]

Arora, K. and Nusslein-Volhard, C (1992). Altered mitotic domains reveal fate map changes in Drosophila embryos mutant for zygotic dorsoventral patterning genes. Development 114, 1003-1024.[Abstract]

Baker, J. and Harland, R (1996). A novel mesoderm inducer, Madr2 functions in the activin signal transduction pathway. Genes Dev 10, 1880-1889.[Abstract/Free Full Text]

Brown, N. H. and Kafatos, F. C (1988). Functional cDNA libraries from Drosophila embryos. J. Mol. Biol 203, 425-437.[Medline]

Brummel, T. J., Twombly, V., Marques, G., Wrana, J. L., Newfeld, S. J., Attisano, L., Massague, J., O'Connor, M. B. and Gelbart, W. M (1994). Characterization and relationship of Dpp receptors encoded by the saxophone and thick veins genes in Drosophila. Cell 78, 251-261.[Medline]

Cavener, D. and Ray, S (1991). Eukaryotic start and stop translation sites. Nucl. Acids Res 19, 3185-3192.[Abstract/Free Full Text]

Chen, X., Rubock, M. and Whitman, M (1996). A transcriptional partner for MAD proteins in TGF-beta signalling. Nature 383, 691-696.[Medline]

Chen, X., Weisberg, E., Fridmacher, V., Watanabe, M., Naco, G. and Whitman, M (1997). Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature 389, 85-89.[Medline]

Chou, T. B. and Perrimon, N (1996). The autosomal FLP-DFS technique for generating germline mosaics in Drosophila melanogaster. Genetics 144, 1673-1679.[Abstract]

Dale, L., Howes, G., Price, B. M. and Smith, J. C (1992). Bone morphogenetic protein 4: a ventralizing factor in early Xenopus development. Development 115, 573-585.[Abstract]

Dearolf, C. R., Tripoulas, N., Biggs, J. and Shearn, A (1988). Molecular consequences of awdb3, a cell-autonomous lethal mutation of Drosophila induced by hybrid dysgenesis. Dev. Biol 129, 169-178.

Dosch, R., Gawantka, V., Delius, H., Blumenstock, C. and Niehrs, C (1997). Bmp-4 acts as a morphogen in dorsoventral mesoderm patterning in Xenopus. Development 124, 2325-2334.[Abstract]

Eppert, K., Scherer, S., Ozcelik, H., Pirone, R., Hoodless, P., Kim, H., Tsui, L., Bapat, B., Gallinger, S., Andrulis, I., Thomsen, G., Wrana, J. and Attisano, L (1996). MADR2 maps to 18q21 and encodes a TGF beta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86, 543-552.[Medline]

Ferguson, E. L. and Anderson, K. V (1992). Decapentaplegic acts as a morphogen to organize dorsal-ventral pattern in the Drosophila embryo. Cell 71, 451-461.[Medline]

Ferguson, E. L. and Anderson, K. V (1992). Localized enhancement and repression of the activity of the TGF-beta family member, decapentaplegic, is necessary for dorsal-ventral pattern formation in the Drosophila embryo. Development 114, 583-597.[Abstract]

Graff, J., Bansal, A. and Melton, D (1996). Xenopus Mad proteins transduce distinct subsets of signals for the TGF beta superfamily. Cell 85, 479-487.[Medline]

Grieder, N. C., Nellen, D., Burke, R., Basler, K. and Affolter, M (1995). Schnurri is required for Drosophila Dpp signaling and encodes a zinc finger protein similar to the mammalian transcription factor PRDII-BF1. Cell 81, 791-800.[Medline]

Hahn, S., Schutte, M., Hoque, A., Moskaluk, C., da, C., LT, Rozenblum, E., Weinstein, C., Fischer, A., Yeo, C., Hruban, R. and Kern, S (1996). DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271, 350-353.[Abstract]

Hammerschmidt, M., Serbedzija, G. N. and McMahon, A. P (1996). Genetic analysis of dorsoventral pattern formation in the zebrafish:requirement of a BMP-like ventralizing activity and its dorsal repressor. Genes Dev 10, 2452-2461.[Abstract/Free Full Text]

Hayashi, H., Abdollah, S., Qiu, Y., Cai, J., Xu, Y. Y., Grinnell, B. W., Richardson, M. A., Topper, J. N., Gimbrone, M., Jr., Wrana, J. L. and Falb, D (1997). The MAD-related protein Smad7 associates with the TGF-beta receptor and functions as an antagonist of TGFbeta signaling. Cell 89, 1165-1173.[Medline]

Heldin, C. H., Miyazono, K. and ten Dijke, P (1997). TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature 390, 465-471.[Medline]

Holley, S. A., Neul, J. L., Attisano, L., Wrana, J. L., Sasai, Y., O'Connor, M. B., De Robertis, E. M. and Ferguson, E. L (1996). The Xenopus dorsalizing factor noggin ventralizes Drosophila embryos by preventing DPP from activating its receptor. Cell 86, 607-617.[Medline]

Hoodless, P., Haerry, T., Abdollah, S., Stapleton, M., O'Connor, M., Attisano, L. and Wrana, J (1996). MADR1, a MAD-related protein that functions in BMP2 signaling pathways. Cell 85, 489-500.[Medline]

Imamura, T., Takase, M., Nishihara, A., Oeda, E., Hanai, J., Kawabata, M. and Miyazono, K (1997). Smad6 inhibits signalling by the TGF-beta superfamily. Nature 389, 622-626.[Medline]

Irish, V. F. and Gelbart, W. M (1987). The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo. Genes Dev 1, 868-879.[Abstract/Free Full Text]

Jones, C. M., Lyons, K. M., Lapan, P. M., Wright, C. V. and Hogan, B. L (1992). DVR-4 (bone morphogenetic protein-4) as a posterior-ventralizing factor in Xenopus mesoderm induction. Development 115, 639-647.[Abstract]

Kim, J., Johnson, K., Chen, H., Carroll, S. and Laughon, A (1997). Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic. Nature 388, 304-308.[Medline]

Lagna, G., Hata, A., Hemmati-Brivanlou, A. and Massague, J (1996). Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways. Nature 383, 832-836.[Medline]

Letsou, A., Arora, K., Wrana, J. L., Simin, K., Twombly, V., Jamal, J., Staehling-Hampton, K., Hoffmann, F. M., Gelbart, W. M., Massague, J. and O'Connor, M. B (1995). Drosophila Dpp signaling is mediated by the punt gene product: a dual ligand-binding type II receptor of the TGF beta receptor family. Cell 80, 899-908.[Medline]

Liu, F., Hata, A., Baker, J., Doody, J., Carcamo, J., Harland, R. and Massague, J (1996). A human Mad protein acting as a BMP-regulated transcriptional activator. Nature 381, 620-623.[Medline]

Liu, X., Sun, Y., Constantinescu, S., Karam, E., Weinberg, R. and Lodish, H (1997). Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells. Proc. Natl. Acad. Sci. USA 94, 10669-10674.[Abstract/Free Full Text]

Locke, J., Kotarski, M. A. and Tartof, K. D (1988). Dosage-dependent modifiers of position effect variegation in Drosophila and a mass action model that explains their effect. Genetics 120, 181-198.[Abstract/Free Full Text]

Macias-Silva, M., Abdollah, S., Hoodless, P., Pirone, R., Attisano, L. and Wrana, J (1996). MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling. Cell 87, 1215-1224.[Medline]

Massague, J (1996). TGF-beta signaling: receptors, transducers, and Mad proteins. Cell 85, 947-950.[Medline]

Mullins, M. C., Hammerschmidt, M., Kane, D. A., Odenthal, J., Brand, M., van Eeden, F. J., Furutani-Seiki, M., Granato, M., Haffter, P., Heisenberg, C. P., Jiang, Y. J., Kelsh, R. N. and Nusslein-Volhard, C (1996). Genes establishing dorsoventral pattern formation in the zebrafish embryo: the ventral specifying genes. Development 123, 81-93.[Abstract]

Nakao, A., Afrakhte, M., Moren, A., Nakayama, T., Christian, J., Heuchel, R., Itoh, S., Kawabata, N., Heldin, N., Heldin, C. and tenDijke, P (1997). Identification of Smad7, a TGF beta-inducible antagonist of TGF-beta signalling. Nature 389, 631-635.[Medline]

Nellen, D., Affolter, M. and Basler, K (1994). Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic. Cell 78, 225-237.[Medline]

Newfeld, S., Chartoff, E., Graff, J., Melton, D. and Gelbart, W (1996). Mothers against dpp encodes a conserved cytoplasmic protein required in DPP/TGF-beta responsive cells. Development 122, 2099-2108.[Abstract]

Newfeld, S., Mehra, A., Singer, M., Wrana, J., Attisano, L. and Gelbart, W (1997). Mothers against dpp participates in a DPP/TGF-beta responsive serine-threonine kinase signal transduction cascade. Development 124, 3167-3176.[Abstract]

Penton, A., Chen, Y., Staehling-Hampton, K., Wrana, J. L., Attisano, L., Szidonya, J., Cassill, J. A., Massague, J. and Hoffmann, F. M (1994). Identification of two bone morphogenetic protein type I receptors in Drosophila and evidence that Brk25D is a decapentaplegic receptor. Cell 78, 239-250.[Medline]

Raftery, L. A., Twombly, V., Wharton, K. and Gelbart, W. M (1995). Genetic screens to identify elements of the decapentaplegic signaling pathway in Drosophila. Genetics 139, 241-254.[Abstract]

Ruberte, E., Marty, T., Nellen, D., Affolter, M. and Basler, K (1995). An absolute requirement for both the type II and type I receptors, punt and thick veins, for dpp signaling in vivo. Cell 80, 889-897.[Medline]

Rushlow, C., Frasch, M., Doyle, H. and Levine, M (1987). Maternal regulation of zerknullt: a homoeobox gene controlling differentiation of dorsal tissues in Drosophila. Nature 330, 583-586.[Medline]

Rushlow, C. and Levine, M (1990). Role of the zerknullt gene in dorsal-ventral pattern formation in Drosophila. Adv. Genet 27, 277-307.[Medline]

Savage, C., Das, P., Finelli, A., Townsend, S., Sun, C., Baird, S. and Padgett, R (1996). Caenorhabditis elegans genes sma-2, sma-3, and sma-4 define a conserved family of transforming growth factor beta pathway components. Proc. Natl. Acad. Sci. USA 93, 790-794.[Abstract/Free Full Text]

Schmucker, D., Taubert, H. and Jackle, H (1992). Formation of the Drosophila larval photoreceptor organ and its neuronal differentiation require continuous Kruppel gene activity. Neuron 9, 1025-1039.[Medline]

Schutte, M., Hruban, R. H., Hedrick, L., Cho, K. R., Nadasdy, G. M., Weinstein, C. L., Bova, G. S., Isaacs, W. B., Cairns, P., Nawroz, H., Sidransky, D., Casero, R., Jr., Meltzer, P. S., Hahn, S. A. and Kern, S. E (1996). DPC4 gene in various tumor types. Cancer Res 56, 2527-2530.[Abstract/Free Full Text]

Sekelsky, J. J., Newfeld, S. J., Raftery, L. A., Chartoff, E. H. and Gelbart, W. M (1995). Genetic characterization and cloning of mothers against dpp, a gene required for decapentaplegic function in Drosophila melanogaster. Genetics 139, 1347-1358.[Abstract]

Shi, Y., Hata, A., Lo, R., Massague, J. and Pavletich, N (1997). A structural basis for mutational inactivation of the tumour suppressor Smad4. Nature 388, 87-93.[Medline]

Spencer, F. A., Hoffmann, F. M. and Gelbart, W. M (1982). Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster. Cell 28, 451-461.[Medline]

St. Johnston, R. D. and Gelbart, W. M (1987). Decapentaplegic transcripts are localized along the dorsal-ventral axis of the Drosophila embryo. EMBO J 6, 2785-2791.[Medline]

Suzuki, A., Chang, C., Yingling, J., Wang, X. and Hemmati-Brivanlou, A (1997). Smad5 induces ventral fates in Xenopus embryo. Dev. Biol 184, 402-405.[Medline]

Tamkun, J. W., Deuring, R., Scott, M. P., Kissinger, M., Pattatucci, A. M., Kaufman, T. C. and Kennison, J. A (1992). brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 68, 561-572.[Medline]

Terracol, R. and Lengyel, J. A (1994). The thick veins gene of Drosophila is required for dorsoventral polarity of the embryo. Genetics 138, 165-178.[Abstract]

Thiagalingam, S., Lengauer, C., Leach, F. S., Schutte, M., Hahn, S. A., Overhauser, J., Willson, J. K., Markowitz, S., Hamilton, S. R., Kern, S. E., Kinzler, K. W. and Vogelstein, B (1996). Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers. Nature Genetics 13, 343-346.[Medline]

Thomsen, G (1996). Xenopus mothers against decapentaplegic is an embryonic ventralizing agent that acts downstream of the BMP-2/4 receptor. Development 122, 2359-2366.[Abstract]

Tsuneizumi, K., Nakayama, T., Kamoshida, Y., Kornberg, T., Christian, J. and Tabata, T (1997). Daughters against dpp modulates dpp organizing activity in Drosophila wing development. Nature 389, 627-631.[Medline]

Twombly, V., Blackman, R. K., Jin, H., Graff, J. M., Padgett, R. W. and Gelbart, W. M (1996). The TGF-signaling pathway is essential for Drosophila oogenesis. Development 122, 1555-1565.[Abstract]

Wakimoto, B. T., Turner, F. R. and Kaufman, T. C (1984). Defects in embryogenesis in mutants associated with the antennapedia gene complex of Drosophila melanogaster. Dev. Biol 102, 147-172.[Medline]

Wharton, K. A., Ray, R. P. and Gelbart, W. M (1993). An activity gradient of decapentaplegic is necessary for the specification of dorsal pattern elements in the Drosophila embryo. Development 117, 807-822.[Abstract]

Wilson, P. A., Lagna, G., Suzuki, A. and Hemmati-Brivanlou, A (1997). Concentration-dependent patterning of the Xenopus ectoderm by BMP4 and its signal transducer Smad1. Development 124, 3177-3184.[Abstract]

Wisotzkey, R. G., Mehra, A., Sutherland, D. J., Dobens, L. L., Liu, X., Dohrmann, C., Attisano, L. and Raftery, L. A (1998). Medea is a Drosophila Smad4 homolog that is differentially required to potentiate Dpp responses. Development 125, 1433-1445.[Abstract]

Wrana, J. L., Attisano, L., Wieser, R., Ventura, F. and Massague, J (1994). Mechanism of activation of the TGF-beta receptor. Nature 370, 341-347.[Medline]

Xie, T., Finelli, A. L. and Padgett, R. W (1994). The Drosophila saxophone gene: a serine-threonine kinase receptor of the TGF-beta superfamily. Science 263, 1756-1759.[Abstract/Free Full Text]

Xiong, W. C. and Montell, C (1993). tramtrack is a transcriptional repressor required for cell fate determination in the Drosophila eye. Genes Dev 7, 1085-1096.[Abstract/Free Full Text]

Yingling, J. M., Datto, M. B., Wong, C., Frederick, J. P., Liberati, N. T. and Wang, X. F (1997). Tumor suppressor Smad4 is a transforming growth factor beta-inducible DNA binding protein. Mol. Cell. Biol 17, 7019-7028.[Abstract]

Zhang, Y., Feng, X., We, R. and Derynck, R (1996). Receptor-associated Mad homologues synergize as effectors of the TGF-beta response. Nature 383, 168-172.[Medline]

Zhang, Y., Musci, T. and Derynck, R. ( (1997). The tumor suppressor Smad4/DPC 4 as a central mediator of Smad function. Current Biol 7, 270-276.[Medline]

CiteULike

Complore

Connotea

Del.icio.us Add to Digg

Digg

Technorati

Twitter What's this?

This article has been cited by other articles:

P. Kahlem and S. J. Newfeld
Informatics approaches to understanding TGF{beta} pathway regulation
Development, November 15, 2009; 136(22): 3729 - 3740.
[Abstract] [Full Text] [PDF]

J. Ng
TGF{beta} signals regulate axonal development through distinct Smad-independent mechanisms
Development, December 15, 2008; 135(24): 4025 - 4035.
[Abstract] [Full Text] [PDF]

Y. A. Zeng, M. Rahnama, S. Wang, W. Sosu-Sedzorme, and E. M. Verheyen
Drosophila Nemo antagonizes BMP signaling by phosphorylation of Mad and inhibition of its nuclear accumulation
Development, June 1, 2007; 134(11): 2061 - 2071.
[Abstract] [Full Text] [PDF]

N. T. Takaesu, E. Herbig, D. Zhitomersky, M. B. O'Connor, and S. J. Newfeld
DNA-binding domain mutations in SMAD genes yield dominant-negative proteins or a neomorphic protein that can activate WG target genes in Drosophila
Development, November 1, 2005; 132(21): 4883 - 4894.
[Abstract] [Full Text] [PDF]

S. Yoshida, L. Soustelle, A. Giangrande, D. Umetsu, S. Murakami, T. Yasugi, T. Awasaki, K. Ito, M. Sato, and T. Tabata
DPP signaling controls development of the lamina glia required for retinal axon targeting in the visual system of Drosophila
Development, October 15, 2005; 132(20): 4587 - 4598.
[Abstract] [Full Text] [PDF]

J. D. Zirin and R. S. Mann
Differing strategies for the establishment and maintenance of teashirt and homothorax repression in the Drosophila wing
Development, November 15, 2004; 131(22): 5683 - 5693.
[Abstract] [Full Text] [PDF]

G. C. Chu, N. R. Dunn, D. C. Anderson, L. Oxburgh, and E. J. Robertson
Differential requirements for Smad4 in TGF{beta}-dependent patterning of the early mouse embryo
Development, August 1, 2004; 131(15): 3501 - 3512.
[Abstract] [Full Text] [PDF]

P. Martin and S. M. Parkhurst
Parallels between tissue repair and embryo morphogenesis
Development, July 1, 2004; 131(13): 3021 - 3034.
[Abstract] [Full Text] [PDF]

D. J. Sutherland, M. Li, X.-q. Liu, R. Stefancsik, and L. A. Raftery
Stepwise formation of a SMAD activity gradient during dorsal-ventral patterning of the Drosophila embryo
Development, December 1, 2003; 130(23): 5705 - 5716.
[Abstract] [Full Text] [PDF]

N. Dumont, A. V. Bakin, and C. L. Arteaga
Autocrine Transforming Growth Factor-beta Signaling Mediates Smad-independent Motility in Human Cancer Cells
J. Biol. Chem., January 24, 2003; 278(5): 3275 - 3285.
[Abstract] [Full Text] [PDF]

H. Chang, C. W. Brown, and M. M. Matzuk
Genetic Analysis of the Mammalian Transforming Growth Factor-{beta} Superfamily
Endocr. Rev., December 1, 2002; 23(6): 787 - 823.
[Abstract] [Full Text] [PDF]

A. Baonza and M. Freeman
Notch signalling and the initiation of neural development in the Drosophila eye
Development, October 15, 2001; 128(20): 3889 - 3898.
[Abstract] [Full Text] [PDF]

E. Decotto and E. L. Ferguson
A positive role for Short gastrulation in modulating BMP signaling during dorsoventral patterning in the Drosophila embryo
Development, October 1, 2001; 128(19): 3831 - 3841.
[Abstract] [Full Text] [PDF]

R. M. Marquez, M. A. Singer, N. T. Takaesu, W. R. Waldrip, Y. Kraytsberg, and S. J. Newfeld
Transgenic Analysis of the Smad Family of TGF-{beta} Signal Transducers in Drosophila melanogaster Suggests New Roles and New Interactions Between Family Members
Genetics, April 1, 2001; 157(4): 1639 - 1648.
[Abstract] [Full Text]

J Torres-Vazquez, S Park, R Warrior, and K Arora
The transcription factor Schnurri plays a dual role in mediating Dpp signaling during embryogenesis
Development, January 5, 2001; 128(9): 1657 - 1670.
[Abstract] [PDF]

R. T. Cox, D. G. McEwen, D. L. Myster, R. J. Duronio, J. Loureiro, and M. Peifer
A Screen for Mutations That Suppress the Phenotype of Drosophila armadillo, the {beta}-Catenin Homolog
Genetics, August 1, 2000; 155(4): 1725 - 1740.
[Abstract] [Full Text]

E. Martin-Blanco, J. C. Pastor-Pareja, and A. Garcia-Bellido
From the Cover: JNK and decapentaplegic signaling control adhesiveness and cytoskeleton dynamics during thorax closure in Drosophila
PNAS, July 5, 2000; 97(14): 7888 - 7893.
[Abstract] [Full Text] [PDF]

R. Fernandez, F. Takahashi, Z. Liu, R. Steward, D. Stein, and E. R. Stanley
The Drosophila Shark tyrosine kinase is required for embryonic dorsal closure
Genes & Dev., March 1, 2000; 14(5): 604 - 614.
[Abstract] [Full Text]

M. P. de Caestecker, T. Yahata, D. Wang, W. T. Parks, S. Huang, C. S. Hill, T. Shioda, A. B. Roberts, and R. J. Lechleider
The Smad4 Activation Domain (SAD) Is a Proline-rich, p300-dependent Transcriptional Activation Domain
J. Biol. Chem., January 21, 2000; 275(3): 2115 - 2122.
[Abstract] [Full Text] [PDF]

K. A. Wharton, J. M. Cook, S. Torres-Schumann, K. de Castro, E. Borod, and D. A. Phillips
Genetic Analysis of the Bone Morphogenetic Protein-Related Gene, gbb, Identifies Multiple Requirements During Drosophila Development
Genetics, June 1, 1999; 152(2): 629 - 640.
[Abstract] [Full Text]

Y.-G. Chen and J. Massague
Smad1 Recognition and Activation by the ALK1 Group of Transforming Growth Factor-beta Family Receptors
J. Biol. Chem., February 5, 1999; 274(6): 3672 - 3677.
[Abstract] [Full Text] [PDF]

F Agnes, M Suzanne, and S Noselli
The Drosophila JNK pathway controls the morphogenesis of imaginal discs during metamorphosis
Development, January 12, 1999; 126(23): 5453 - 5462.
[Abstract] [PDF]

J Zeitlinger and D Bohmann
Thorax closure in Drosophila: involvement of Fos and the JNK pathway
Development, January 9, 1999; 126(17): 3947 - 3956.
[Abstract] [PDF]

A Jazwinska, C Rushlow, and S Roth
The role of brinker in mediating the graded response to Dpp in early Drosophila embryos
Development, January 8, 1999; 126(15): 3323 - 3334.
[Abstract] [PDF]

M Hild, A Dick, G. Rauch, A Meier, T Bouwmeester, P Haffter, and M Hammerschmidt
The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo
Development, January 5, 1999; 126(10): 2149 - 2159.
[Abstract] [PDF]

M. Ricos, N Harden, K. Sem, L Lim, and W Chia
Dcdc42 acts in TGF-beta signaling during Drosophila morphogenesis: distinct roles for the Drac1/JNK and Dcdc42/TGF-beta cascades in cytoskeletal regulation
J. Cell Sci., January 4, 1999; 112(8): 1225 - 1235.
[Abstract] [PDF]

T. Brummel, S. Abdollah, T. E. Haerry, M. J. Shimell, J. Merriam, L. Raftery, J. L. Wrana, and M. B. O'Connor
The Drosophila Activin receptor Baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development
Genes & Dev., January 1, 1999; 13(1): 98 - 111.
[Abstract] [Full Text]

C. Pouponnot, L. Jayaraman, and J. Massague
Physical and Functional Interaction of SMADs and p300/CBP
J. Biol. Chem., September 4, 1998; 273(36): 22865 - 22868.
[Abstract] [Full Text] [PDF]

H. Inoue, T. Imamura, Y. Ishidou, M. Takase, Y. Udagawa, Y. Oka, K. Tsuneizumi, T. Tabata, K. Miyazono, and M. Kawabata
Interplay of Signal Mediators of Decapentaplegic (Dpp): Molecular Characterization of Mothers against dpp, Medea, and Daughters against dpp
Mol. Biol. Cell, August 1, 1998; 9(8): 2145 - 2156.
[Abstract] [Full Text]

K. A. Guss, C. E. Nelson, A. Hudson, M. E. Kraus, and S. B. Carroll
Control of a Genetic Regulatory Network by a Selector Gene
Science, May 11, 2001; 292(5519): 1164 - 1167.
[Abstract] [Full Text]

H. Kirkpatrick, K. Johnson, and A. Laughon
Repression of Dpp Targets by Binding of Brinker to Mad Sites
J. Biol. Chem., May 18, 2001; 276(21): 18216 - 18222.
[Abstract] [Full Text] [PDF]

K. Raymond, E. Bergeret, M.-C. Dagher, R. Breton, R. Griffin-Shea, and M.-O. Fauvarque
The Rac GTPase-activating Protein RotundRacGAP Interferes with Drac1 and Dcdc42 Signalling in Drosophila melanogaster
J. Biol. Chem., September 14, 2001; 276(38): 35909 - 35916.
[Abstract] [Full Text] [PDF]

This Article

Summary

Full Text (PDF)

Alert me when this article is cited

Alert me if a correction is posted

Services

Email this article to a friend

Similar articles in this journal

Similar articles in PubMed

Alert me to new issues of the journal

Download to citation manager

Citing Articles

Citing Articles via HighWire

Citing Articles via Google Scholar

Google Scholar

Articles by Hudson, J. B.

Articles by Ferguson, E. L.

Search for Related Content

PubMed

PubMed Citation

Articles by Hudson, J. B.

Articles by Ferguson, E. L.

Social Bookmarking

What's this?

				J. Ng TGF{beta} signals regulate axonal development through distinct Smad-independent mechanisms Development, December 15, 2008; 135(24): 4025 - 4035. [Abstract] [Full Text] [PDF]

				Y. A. Zeng, M. Rahnama, S. Wang, W. Sosu-Sedzorme, and E. M. Verheyen Drosophila Nemo antagonizes BMP signaling by phosphorylation of Mad and inhibition of its nuclear accumulation Development, June 1, 2007; 134(11): 2061 - 2071. [Abstract] [Full Text] [PDF]

				N. T. Takaesu, E. Herbig, D. Zhitomersky, M. B. O'Connor, and S. J. Newfeld DNA-binding domain mutations in SMAD genes yield dominant-negative proteins or a neomorphic protein that can activate WG target genes in Drosophila Development, November 1, 2005; 132(21): 4883 - 4894. [Abstract] [Full Text] [PDF]

				S. Yoshida, L. Soustelle, A. Giangrande, D. Umetsu, S. Murakami, T. Yasugi, T. Awasaki, K. Ito, M. Sato, and T. Tabata DPP signaling controls development of the lamina glia required for retinal axon targeting in the visual system of Drosophila Development, October 15, 2005; 132(20): 4587 - 4598. [Abstract] [Full Text] [PDF]

				J. D. Zirin and R. S. Mann Differing strategies for the establishment and maintenance of teashirt and homothorax repression in the Drosophila wing Development, November 15, 2004; 131(22): 5683 - 5693. [Abstract] [Full Text] [PDF]

				G. C. Chu, N. R. Dunn, D. C. Anderson, L. Oxburgh, and E. J. Robertson Differential requirements for Smad4 in TGF{beta}-dependent patterning of the early mouse embryo Development, August 1, 2004; 131(15): 3501 - 3512. [Abstract] [Full Text] [PDF]

				P. Martin and S. M. Parkhurst Parallels between tissue repair and embryo morphogenesis Development, July 1, 2004; 131(13): 3021 - 3034. [Abstract] [Full Text] [PDF]

				D. J. Sutherland, M. Li, X.-q. Liu, R. Stefancsik, and L. A. Raftery Stepwise formation of a SMAD activity gradient during dorsal-ventral patterning of the Drosophila embryo Development, December 1, 2003; 130(23): 5705 - 5716. [Abstract] [Full Text] [PDF]

				N. Dumont, A. V. Bakin, and C. L. Arteaga Autocrine Transforming Growth Factor-beta Signaling Mediates Smad-independent Motility in Human Cancer Cells J. Biol. Chem., January 24, 2003; 278(5): 3275 - 3285. [Abstract] [Full Text] [PDF]

				H. Chang, C. W. Brown, and M. M. Matzuk Genetic Analysis of the Mammalian Transforming Growth Factor-{beta} Superfamily Endocr. Rev., December 1, 2002; 23(6): 787 - 823. [Abstract] [Full Text] [PDF]

				A. Baonza and M. Freeman Notch signalling and the initiation of neural development in the Drosophila eye Development, October 15, 2001; 128(20): 3889 - 3898. [Abstract] [Full Text] [PDF]

				E. Decotto and E. L. Ferguson A positive role for Short gastrulation in modulating BMP signaling during dorsoventral patterning in the Drosophila embryo Development, October 1, 2001; 128(19): 3831 - 3841. [Abstract] [Full Text] [PDF]

				R. M. Marquez, M. A. Singer, N. T. Takaesu, W. R. Waldrip, Y. Kraytsberg, and S. J. Newfeld Transgenic Analysis of the Smad Family of TGF-{beta} Signal Transducers in Drosophila melanogaster Suggests New Roles and New Interactions Between Family Members Genetics, April 1, 2001; 157(4): 1639 - 1648. [Abstract] [Full Text]

				J Torres-Vazquez, S Park, R Warrior, and K Arora The transcription factor Schnurri plays a dual role in mediating Dpp signaling during embryogenesis Development, January 5, 2001; 128(9): 1657 - 1670. [Abstract] [PDF]

				R. T. Cox, D. G. McEwen, D. L. Myster, R. J. Duronio, J. Loureiro, and M. Peifer A Screen for Mutations That Suppress the Phenotype of Drosophila armadillo, the {beta}-Catenin Homolog Genetics, August 1, 2000; 155(4): 1725 - 1740. [Abstract] [Full Text]

				E. Martin-Blanco, J. C. Pastor-Pareja, and A. Garcia-Bellido From the Cover: JNK and decapentaplegic signaling control adhesiveness and cytoskeleton dynamics during thorax closure in Drosophila PNAS, July 5, 2000; 97(14): 7888 - 7893. [Abstract] [Full Text] [PDF]

				R. Fernandez, F. Takahashi, Z. Liu, R. Steward, D. Stein, and E. R. Stanley The Drosophila Shark tyrosine kinase is required for embryonic dorsal closure Genes & Dev., March 1, 2000; 14(5): 604 - 614. [Abstract] [Full Text]

				M. P. de Caestecker, T. Yahata, D. Wang, W. T. Parks, S. Huang, C. S. Hill, T. Shioda, A. B. Roberts, and R. J. Lechleider The Smad4 Activation Domain (SAD) Is a Proline-rich, p300-dependent Transcriptional Activation Domain J. Biol. Chem., January 21, 2000; 275(3): 2115 - 2122. [Abstract] [Full Text] [PDF]

				K. A. Wharton, J. M. Cook, S. Torres-Schumann, K. de Castro, E. Borod, and D. A. Phillips Genetic Analysis of the Bone Morphogenetic Protein-Related Gene, gbb, Identifies Multiple Requirements During Drosophila Development Genetics, June 1, 1999; 152(2): 629 - 640. [Abstract] [Full Text]

				Y.-G. Chen and J. Massague Smad1 Recognition and Activation by the ALK1 Group of Transforming Growth Factor-beta Family Receptors J. Biol. Chem., February 5, 1999; 274(6): 3672 - 3677. [Abstract] [Full Text] [PDF]

				F Agnes, M Suzanne, and S Noselli The Drosophila JNK pathway controls the morphogenesis of imaginal discs during metamorphosis Development, January 12, 1999; 126(23): 5453 - 5462. [Abstract] [PDF]

				J Zeitlinger and D Bohmann Thorax closure in Drosophila: involvement of Fos and the JNK pathway Development, January 9, 1999; 126(17): 3947 - 3956. [Abstract] [PDF]

				A Jazwinska, C Rushlow, and S Roth The role of brinker in mediating the graded response to Dpp in early Drosophila embryos Development, January 8, 1999; 126(15): 3323 - 3334. [Abstract] [PDF]

				M Hild, A Dick, G. Rauch, A Meier, T Bouwmeester, P Haffter, and M Hammerschmidt The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo Development, January 5, 1999; 126(10): 2149 - 2159. [Abstract] [PDF]

				M. Ricos, N Harden, K. Sem, L Lim, and W Chia Dcdc42 acts in TGF-beta signaling during Drosophila morphogenesis: distinct roles for the Drac1/JNK and Dcdc42/TGF-beta cascades in cytoskeletal regulation J. Cell Sci., January 4, 1999; 112(8): 1225 - 1235. [Abstract] [PDF]

				T. Brummel, S. Abdollah, T. E. Haerry, M. J. Shimell, J. Merriam, L. Raftery, J. L. Wrana, and M. B. O'Connor The Drosophila Activin receptor Baboon signals through dSmad2 and controls cell proliferation but not patterning during larval development Genes & Dev., January 1, 1999; 13(1): 98 - 111. [Abstract] [Full Text]

				C. Pouponnot, L. Jayaraman, and J. Massague Physical and Functional Interaction of SMADs and p300/CBP J. Biol. Chem., September 4, 1998; 273(36): 22865 - 22868. [Abstract] [Full Text] [PDF]

				H. Inoue, T. Imamura, Y. Ishidou, M. Takase, Y. Udagawa, Y. Oka, K. Tsuneizumi, T. Tabata, K. Miyazono, and M. Kawabata Interplay of Signal Mediators of Decapentaplegic (Dpp): Molecular Characterization of Mothers against dpp, Medea, and Daughters against dpp Mol. Biol. Cell, August 1, 1998; 9(8): 2145 - 2156. [Abstract] [Full Text]

				K. A. Guss, C. E. Nelson, A. Hudson, M. E. Kraus, and S. B. Carroll Control of a Genetic Regulatory Network by a Selector Gene Science, May 11, 2001; 292(5519): 1164 - 1167. [Abstract] [Full Text]

				H. Kirkpatrick, K. Johnson, and A. Laughon Repression of Dpp Targets by Binding of Brinker to Mad Sites J. Biol. Chem., May 18, 2001; 276(21): 18216 - 18222. [Abstract] [Full Text] [PDF]