Medea is a Drosophila Smad4 homolog that is differentially required to potentiate DPP responses

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				P. Martin and S. M. Parkhurst Parallels between tissue repair and embryo morphogenesis Development, July 1, 2004; 131(13): 3021 - 3034. [Abstract] [Full Text] [PDF]

				X. Song, M. D. Wong, E. Kawase, R. Xi, B. C. Ding, J. J. McCarthy, and T. Xie Bmp signals from niche cells directly repress transcription of a differentiation-promoting gene, bag of marbles, in germline stem cells in the Drosophila ovary Development, March 15, 2004; 131(6): 1353 - 1364. [Abstract] [Full Text] [PDF]

				E. Kawase, M. D. Wong, B. C. Ding, and T. Xie Gbb/Bmp signaling is essential for maintaining germline stem cells and for repressing bam transcription in the Drosophila testis Development, March 15, 2004; 131(6): 1365 - 1375. [Abstract] [Full Text] [PDF]

				D. J. Sutherland, M. Li, X.-q. Liu, R. Stefancsik, and L. A. Raftery Stepwise formation of a SMAD activity gradient during dorsal-ventral patterning of the Drosophila embryo Development, December 1, 2003; 130(23): 5705 - 5716. [Abstract] [Full Text] [PDF]

				H. Chang, C. W. Brown, and M. M. Matzuk Genetic Analysis of the Mammalian Transforming Growth Factor-{beta} Superfamily Endocr. Rev., December 1, 2002; 23(6): 787 - 823. [Abstract] [Full Text] [PDF]

				J. L. Vivian, Y. Chen, D. Yee, E. Schneider, and T. Magnuson An allelic series of mutations in Smad2 and Smad4 identified in a genotype-based screen of N-ethyl-N- nitrosourea-mutagenized mouse embryonic stem cells PNAS, November 26, 2002; 99(24): 15542 - 15547. [Abstract] [Full Text] [PDF]

				B. Peng, J. B. Fleming, T. Breslin, A. M. Grau, S. Fojioka, J. L. Abbruzzese, D. B. Evans, D. Ayers, K. Wathen, T. Wu, et al. Suppression of Tumorigenesis and Induction of p15ink4b by Smad4/DPC4 in Human Pancreatic Cancer Cells Clin. Cancer Res., November 1, 2002; 8(11): 3628 - 3638. [Abstract] [Full Text] [PDF]

				S. J. Newfeld and N. T. Takaesu An Analysis Using the hobo Genetic System Reveals That Combinatorial Signaling by the Dpp and Wg Pathways Regulates dpp Expression in Leading Edge Cells of the Dorsal Ectoderm in Drosophila melanogaster Genetics, June 1, 2002; 161(2): 685 - 692. [Abstract] [Full Text] [PDF]

				D. Maurice, C. E. Pierreux, M. Howell, R. E. Wilentz, M. J. Owen, and C. S. Hill Loss of Smad4 Function in Pancreatic Tumors. C-TERMINAL TRUNCATION LEADS TO DECREASED STABILITY J. Biol. Chem., November 9, 2001; 276(46): 43175 - 43181. [Abstract] [Full Text] [PDF]

				E. Decotto and E. L. Ferguson A positive role for Short gastrulation in modulating BMP signaling during dorsoventral patterning in the Drosophila embryo Development, October 1, 2001; 128(19): 3831 - 3841. [Abstract] [Full Text] [PDF]

				M. A. Su, R. G. Wisotzkey, and S. J. Newfeld A Screen for Modifiers of decapentaplegic Mutant Phenotypes Identifies lilliputian, the Only Member of the Fragile-X/Burkitt's Lymphoma Family of Transcription Factors in Drosophila melanogaster Genetics, February 1, 2001; 157(2): 717 - 725. [Abstract] [Full Text]

				J Torres-Vazquez, S Park, R Warrior, and K Arora The transcription factor Schnurri plays a dual role in mediating Dpp signaling during embryogenesis Development, January 5, 2001; 128(9): 1657 - 1670. [Abstract] [PDF]

				C. Sirard, S. Kim, C. Mirtsos, P. Tadich, P. A. Hoodless, A. Itie, R. Maxson, J. L. Wrana, and T. W. Mak Targeted Disruption in Murine Cells Reveals Variable Requirement for Smad4 in Transforming Growth Factor beta -related Signaling J. Biol. Chem., January 21, 2000; 275(3): 2063 - 2070. [Abstract] [Full Text] [PDF]

				E. PIEK, C.-H. HELDIN, and P. TEN DIJKE Specificity, diversity, and regulation in TGF-{beta} superfamily signaling FASEB J, December 1, 1999; 13(15): 2105 - 2124. [Abstract] [Full Text]

				P. J. CHIAO, K. K. HUNT, A. M. GRAU, A. ABRAMIAN, J. FLEMING, W. ZHANG, T. BRESLIN, J. L. ABBRUZZESE, and D. B. EVANS Tumor Suppressor Gene Smad4/DPC4, Its Downstream Target Genes, and Regulation of Cell Cycle Ann. N.Y. Acad. Sci., June 30, 1999; 880(1): 31 - 37. [Abstract] [Full Text] [PDF]

				K. A. Wharton, J. M. Cook, S. Torres-Schumann, K. de Castro, E. Borod, and D. A. Phillips Genetic Analysis of the Bone Morphogenetic Protein-Related Gene, gbb, Identifies Multiple Requirements During Drosophila Development Genetics, June 1, 1999; 152(2): 629 - 640. [Abstract] [Full Text]

				S. J. Newfeld, R. G. Wisotzkey, and S. Kumar Molecular Evolution of a Developmental Pathway: Phylogenetic Analyses of Transforming Growth Factor-� Family Ligands, Receptors and Smad Signal Transducers Genetics, June 1, 1999; 152(2): 783 - 795. [Abstract] [Full Text]

				N. Masuyama, H. Hanafusa, M. Kusakabe, H. Shibuya, and E. Nishida Identification of Two Smad4 Proteins in Xenopus. THEIR COMMON AND DISTINCT PROPERTIES J. Biol. Chem., April 23, 1999; 274(17): 12163 - 12170. [Abstract] [Full Text] [PDF]

				Y.-G. Chen and J. Massague Smad1 Recognition and Activation by the ALK1 Group of Transforming Growth Factor-beta Family Receptors J. Biol. Chem., February 5, 1999; 274(6): 3672 - 3677. [Abstract] [Full Text] [PDF]

				A Jazwinska, C Rushlow, and S Roth The role of brinker in mediating the graded response to Dpp in early Drosophila embryos Development, January 8, 1999; 126(15): 3323 - 3334. [Abstract] [PDF]

				M Hild, A Dick, G. Rauch, A Meier, T Bouwmeester, P Haffter, and M Hammerschmidt The smad5 mutation somitabun blocks Bmp2b signaling during early dorsoventral patterning of the zebrafish embryo Development, January 5, 1999; 126(10): 2149 - 2159. [Abstract] [PDF]

				J. Thatcher, C Haun, and P. Okkema The DAF-3 Smad binds DNA and represses gene expression in the Caenorhabditis elegans pharynx Development, January 1, 1999; 126(1): 97 - 107. [Abstract] [PDF]